Clinical trials: Functional Neurological Disorder
Healthy Aging, Cognitive Function 1, Social
Understanding Cerebral Blood Flow Dynamics for Alzheimer's Disease Prevention Through Exercise
Dementia is one of the leading causes of disability worldwide. Underlying biological mechanisms are crucial in preclinical stages of Alzheimer's disease (AD).
- Conditions
- Healthy Aging, Cognitive Function 1, Social, Cerebrovascular Circulation, Blood Flow
- Trial name
- flADex (NCT06584656)
- Testing
- Aerobic exercise condition, Resistance exercise condition
- Where
- 2 sites in Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Functional Movement Disorders, Reproducibility of Results
Aspects of Validity of the Single Leg Squat Test: A Cohort Study of Female Soccer Players.
Movement screening tests to identify deficits or poor movement quality is commonly used in soccer and other sports to assess injury, to evaluate rehabilitation goals and return to sport after injury.
- Conditions
- Functional Movement Disorders, Reproducibility of Results, Sports Medicine
- Trial name
- NCT05289284
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Abdominal Pain
Heart Rate Variability in Children With a Functional Gastrointestinal Disorder
The current study is designed to assess relationships between anxiety/stress, autonomic nervous system balance, and electrical activity in the stomach before and after eating/drinking in children with abdominal pain.
- Trial name
- NCT00195975
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Cerebral Palsy
Does Botulinum Toxin Injections Improve Outdoor Activity in Children With Cerebral Palsy?- a Pilot Study
Background: Motor impairment limits social and recreational activities in children with cerebral palsy (CP), compromising participation and impacting on quality of life.
- Trial name
- NCT01335100
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Cerebral Microvascular Dysfunction, Cerebral Small Vessel Diseases
PRospective Observation on CErebral microvaScular Structure and Function
This is a population-based prospective cohort study, aiming to assess the prevalence, distributional characteristics, and dynamic change of cerebral small vessel dysfunction in a Chinese community population using advanced…
- Conditions
- Cerebral Microvascular Dysfunction, Cerebral Small Vessel Diseases, Cognitive Dysfunction, Cerebrovascular Disorders
- Trial name
- PROCESS (NCT06579677)
- Testing
- Without any intervention
- Where
- 2 sites in China
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Concussion, Mild, Post-Concussion Symptoms
Effects of Bright Light Therapy in Mild Traumatic Brain Injury
Mild traumatic brain injuries (mTBI) or "concussions" are an increasingly prevalent injury in our society. Patients with post-concussion syndrome have been shown to have deficits on tests of short term memory, divided attention…
- Conditions
- Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
- Trial name
- NCT01747811
- Testing
- wavelength-1 bright light, wavelength-2 bright light
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Multiple Sclerosis
Body Awareness, Trunk Stability, and Arm Function in MS
The aim of this study is to investigate the relationship between body awareness, trunk stabilization, and upper extremity functionality in patients with Multiple Sclerosis (MS).
- Trial name
- NCT07151534
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Joint Pain, Joint Stiffness
Effects of Maine Oils on Joint Stiffness and Pain
Joint pain has a negative effect on quality of life by limiting daily physical activity, and can lead to reduced work capacity, chronic stress, sleep problems, fatigue and reduced social life.
- Conditions
- Joint Pain, Joint Stiffness, Joint Function
- Trial name
- MAR-LEDD (NCT07786181)
- Testing
- Herring oil, Omega-11 concentrate produced from herring oi, Control oil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Physical Therapy, Upper Extremity Function
Upper Extremity Function, Shoulder Position Sense and Disability Level İn Patients With Multiple Sclerosis
The purposes of this study is to investigate the relationship between upper extremity muscle function and shoulder position sense in patients with Multiple Sclerosis (MS) and which best projects the disability status.
- Conditions
- Physical Therapy, Upper Extremity Function, Position Sense
- Trial name
- NCT03846336
- Testing
- Upper extremity function, Shoulder position sense
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Sarcopenia
Understanding Loss of Muscle Mass and Function
Sarcopenia is a loss of muscle mass and function that develops during aging. But sarcopenia is also observed in several other conditions: chronic diseases, cancers, viral infections, renal / respiratory insufficiency, immobility…
- Trial name
- SAMANTHA (NCT04004039)
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cognitive Change
Impact of Challenging Engagement on Cognition in Older Adults
The study will enroll 90 participants in the "Impact of Challenging Engagement" study and assign them to one of three groups: high-demand photography, moderate-demand photography, and active placebo.
- Trial name
- engAGE (NCT03962439)
- Testing
- High-Demand Photography, Moderate-Demand Photography, At-Home Engagement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Irritable Bowel Syndrome, Abdominal Pain
Bifidobacterium Infantis M-63 Improves Mental Health in Irritable Bowel Syndrome Developed After a Major Flood Disaster
A 3-month study was conducted in flood victims from affected villages in the Tumpat district, Kelantan. Participants were given either probiotic, Bifidobacterium infantis M63 (M-63 group) or no probiotics (control group) for…
- Conditions
- Irritable Bowel Syndrome, Abdominal Pain, Small Intestinal Bacterial Overgrowth
- Trial name
- NCT03318614
- Testing
- Probiotics M-63, Control group
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Spinal Cord Injuries
Autoantibodies on Spinal Cord Injury
The purpose of this study is to determine the autoantibody profiles after spinal cord injury and their role in spontaneous functional recovery.
- Trial name
- NCT02493543
- Testing
- Blood collection
- Where
- 2 sites in Germany, Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Hospital Nacional de Parapléjicos de Toledo
Mild Traumatic Brain Injury, Concussion, Binocular Visual Function
An Early Prospective Study of the Traq™ Device for Characterization of Binocular Ocular Function in Normal Subjects and Subjects With Recent Traumatic Brain Injury
The early prospective study of Traq™ (an investigational binocular ophthalmic neurodiagnostic device) will measure binocular ocular functions (bilateral foveal fixation, foveal binocularity, and fovea-tracked saccadic latency) in…
- Conditions
- Mild Traumatic Brain Injury, Concussion, Binocular Visual Function, Neuro-Ophthalmology, Saccadic Eye Movements
- Trial name
- REB-001 (NCT07742878)
- Testing
- Binocular ophthalmic neurodiagnostic device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Sleep Apnea, Obstructive
Evaluating the Relationship Between Sleep-Disordered Breathing and Daytime Alertness
Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person repeatedly stops breathing, or experiences shallow breathing for short periods of time during sleep.
- Trial name
- NCT00393913
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Spinal Cord Injury
Body Temperature in Persons With Tetraplegia When Exposed to Heat
The deleterious effects of hyperthermia are well appreciated in able-bodied persons. However, the consequences of impaired regulation of normal body temperature on cognitive performance of persons with tetraplegia is not known.
- Trial name
- NCT01890915
- Testing
- Heat Exposure
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Migraine in Children, Complex Regional Pain Syndromes
Supraspinal Processing of Sensory Aspects of Pain
The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients.
- Conditions
- Migraine in Children, Complex Regional Pain Syndromes, Musculoskeletal Pain, Functional Abdominal Pain Syndrome
- Trial name
- SCP (NCT05814497)
- Testing
- Multisensory Task, Graphesthesia, Divided attention
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Parkinson's Disease (PD)
Untreated Parkinson's Disease Work-up Assessing Resident Microbiota and Duodenal Barrier Function
The UPWARD study is a prospective hypothesis-generating study in individuals with untreated Parkinson's disease (PD) and age-matched healthy controls (HCs).
- Trial name
- UPWARD (NCT07418658)
- Testing
- Invasive sampling procedures, Non-invasive sampling procedures
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Parkinson's Disease
Multi-chip Meta-analysis of Parkinson's Disease for Clinical Validation of Small Samples of Key Genes in Disease
The research team used meta-analytical statistical methods to integrate the results of different research groups on Parkinson's disease, using meta-analysis to find key genes related to the pathogenesis and development of…
- Trial name
- NCT03848455
- Testing
- genetic diagnosis
- Where
- China
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Horton's Disease, Infectious Disease
Quantitative and Functional Study of TH17 Lymphocytes in Horton's Disease (HD)
The aim of this open, controlled, multicentre biomedical research study is to identify new markers specifically associated with Horton's disease.
- Conditions
- Horton's Disease, Infectious Disease, Neoplasia, Solid Tumor
- Trial name
- NCT02065297
- Testing
- 1 blood sample, 2 to 3 blood samples (at inclusion, at 3 months and at 6 months in cases of relapse)
- Where
- 3 sites in France
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
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