Clinical trials: Genetic Counselling
Genetic Counseling Profession
Me-GC: A Randomized Controlled Trial of Meditation for Genetic Counselors
This study is designed to determine whether meditation is beneficial for genetic counselors and genetic counseling students. The main goal is to see if meditation can help with professional well-being (burnout for genetic…
- Trial name
- NCT03723018
- Testing
- Meditation
- Where
- United States
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Weight Loss
Telenutrition Weight Loss Study for Men
This study is a 12-week pilot randomized controlled trial to test the feasibility and effectiveness of a home telenutrition weight loss program in men in West Virginia.
- Conditions
- Obesity, Weight Loss, Men
- Trial name
- NCT02938897
- Testing
- Registered Dietitian Nutritionist (RDN) Support, Diet-related educational materials, Self-monitoring tools
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Congenital Adrenal Hyperplasia
Qualitative Research on Women With Congenital Adrenal Hyperplasia
This qualitative interview-based study will investigate the impact that living with congenital adrenal hyperplasia has for women in the following areas: health-related quality of life (HRQL), psychological health, and…
- Trial name
- CAH (NCT00559078)
- Testing
- Interview
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lehigh University
Genetic Disease, CNV
Reinterpretation of CNV With Unknown Significance: a 5-year Retrospective Analysis
We aim to assess the usefulness of systematic reinterpretation of CNV of unknown significance. To investigate this question we will study all CNV of unknown significance detected between 2010 and 2017.
- Conditions
- Genetic Disease, CNV, Genetic Counseling, Array CGH
- Trial name
- ReAC (NCT04575350)
- Testing
- reinterpretation of CNV
- Where
- France
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Anxiety, Attitude
The Effect of Prenatal Genetic Counseling Service
The research is planned as a randomized controlled experimental study in order to determine the effect of prenatal genetic counseling service on the anxiety levels and attitudes of pregnant women towards prenatal diagnostic tests…
- Trial name
- NCT05508854
- Testing
- prenatal genetic counselling
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Mersin University
Schizophrenia
Schizophrenia and Genetic Counseling
This research is designed to investigate the perceptions and opinions of individuals who either have schizophrenia or who have a family member with schizophrenia, in relation to genetic counseling.
- Trial name
- NCT00111202
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Lawrence College
Decision Making, Chromosome Abnormality
Efficacy of Counseling for Prenatal Screening and Diagnostic Tests on Pregnant Women: Randomised Controlled Study
The aim of this study was to evaluate the effect of counseling for prenatal screening and diagnostic tests on pregnant women's decisional conflict, being sure of the decision, anxiety levels, and attitudes towards the tests.
- Conditions
- Decision Making, Chromosome Abnormality, Anxiety, Knowledge, Attitudes, Practice
- Trial name
- NCT03825978
- Testing
- Prenatal Genetic Counseling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Hereditary Cancer Syndromes
Feasibility Study of a Chatbot AI-Driven Preliminary Screening System for Hereditary Cancer Syndromes
This study aims to assess the feasibility of implementing an AI-based hereditary cancer preliminary screening system that has already been developed.
- Trial name
- NCT07901543
- Testing
- Hereditary cancer preliminary screening chatbot
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Breast Cancer, Hereditary Breast Cancer
Testing a Culturally Adapted Telephone Genetic Counseling Intervention
Participating in genetic cancer risk assessments (GCRA) for hereditary breast and ovarian cancer (HBOC) can inform treatment and risk management decisions and improve breast cancer outcomes.
- Trial name
- NCT03959267
- Testing
- Telephone Genetic Counseling
- Where
- 4 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Education
Transition From Research to Disclosure in Human Genetics
The goal of this study is to design a means of providing research families, from diverse geographical locations, the chance to receive genetic testing after having been educated by video, and meetings or telephone conversations…
- Trial name
- NCT00505466
- Testing
- Genetic Counseling
- Where
- United States
- Volunteers
- 577 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Hereditary Breast and Ovarian Cancer Syndrome, Lynch Syndrome
Telemedicine vs. Face-to-Face Cancer Genetic Counseling
Cancer genetic counseling (CGC) has been found to have "substantial" benefits for individuals with breast cancer and their family members; it has been deemed by multiple organizations as "standard of care" for women with breast…
- Trial name
- NCT00609505
- Testing
- Telemedicine, Face-to-Face
- Where
- 4 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Duke University
Patient Education
Preimplantation Genetic Testing for Aneuploidy Counseling
Purpose: To evaluate preimplantation genetic testing counseling interventions on patients undergoing in vitro fertilization treatment.
- Trial name
- PGT-A (NCT06018454)
- Testing
- Handout on PGT-A, Handout on PGT-A and genetic counseling
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Eyup Hakan Duran
Whole Genome Sequencing
South-seq: Deoxyribonucleic Acid (DNA) Sequencing for Newborn Nurseries in the South
2,000 infants with signs suggestive of a genetic disorder being treated at a neonatal intensive care unit (NICU) in which African-American and rural populations are highly represented will be enrolled.
- Trial name
- NCT03842995
- Testing
- Genetic Counselor, Trained Healthcare Provider
- Where
- 3 sites in United States
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Alzheimer's Disease
Risk Evaluation and Education for Alzheimer's Disease
The purpose of this study is to determine the characteristics of those who obtain genetic susceptibility testing for Alzheimer's disease with APOE disclosure and to study the psychological and behavioral consequences of providing…
- Trial name
- REVEAL I (NCT00571025)
- Testing
- APOE Disclosure
- Where
- 3 sites in United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Cerebellar Ataxias, Spastic Paraplegias
SPATAX: Clinical and Genetic Analysis of Cerebellar Ataxias and Spastic Paraplegias
Cerebellar ataxias (CA) and spastic paraplegias (SP) are genetically and clinically very heterogeneous. More than 40 loci are already known but the number of phenotypes is even greater suggesting further genetic heterogeneity.
- Trial name
- Spatax (NCT00140829)
- Where
- 27 sites in Algeria, Belgium and 13 more
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Aneuploidy, Birth Defect
Use of Videos to Improve Patient Knowledge on Prenatal Genetics
This is a randomized controlled trial of a low income and low health literacy population of pregnant women from a diverse racial and ethnic background to assess the effectiveness of a pre-visit educational video on prenatal…
- Trial name
- VPE (NCT03816423)
- Testing
- video
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Healthy Volunteers
Are Genetic Counselors Screening for Adolescent Suicide Risk?
Background: Suicide is one of the main causes of death for adolescents in the U.S. The most effective way to decrease suicide is by training doctors to recognize the risk factors in their clients.
- Trial name
- NCT02486120
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Hereditary Breast and Ovarian Cancer
Identification and Referral of Women at Risk for Hereditary Breast/Ovarian Cancer
The purpose of this study is to identify the most effective means of follow-up for women who screen positive on B-RST (Breast Cancer Genetics Referral Screening Tool) applied in the standard clinical setting of mammography, to…
- Trial name
- NCT02786147
- Testing
- Breast Cancer Genetics Referral Screening Tool 3.0, Standard Handout, Physician Notification
- Where
- 2 sites in United States
- Volunteers
- 665 people, healthy volunteers welcome
- Sponsor
- Emory University
Prostate Cancer, Prostate Biopsy
The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and Treatment
Prostate cancer is now the most common cancer in men in the Western world. In the United Kingdom (UK), there were over 52,000 new cases diagnosed in 2016-2018 and a lifetime risk of 1 in 8.
- Conditions
- Prostate Cancer, Prostate Biopsy, Genetic Counselling, Genetic Markers
- Trial name
- PROFILE (NCT02543905)
- Testing
- Prostate MRI and Biopsy
- Where
- United Kingdom
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Institute of Cancer Research, United Kingdom
Smoking Cessation
Genetically Informed Smoking Cessation Trial
The investigators' goal is to identify the most appropriate smoking cessation treatments for smokers based on genetic information. Smokers try to quit smoking but relapses are common.
- Trial name
- GISC (NCT02351167)
- Testing
- Combination NRT (Nicotine patch, Nicotine lozenge), Varenicline, Intensive smoking counseling
- Where
- United States
- Volunteers
- 822 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine