Clinical trials: Genicular Nerves Block
Tibial Plateau Fractures
Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the…
- Trial name
- NCT06639503
- Testing
- Bupivacain
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Chicago
Transcutaneous, Pulsed Radiofrequency
Transcutaneous Pulsed Radiofrequency Application Plus Genicular Nerve Block Versus Intraarticular Hyaluronic Acid Injection for Management of Chronic Pain in Knee Osteoarthritis.
The aim of the present study is to compare the analgesic efficacy of combined transcutaneous pulsed radiofrequency plus genicular nerve block with bupivacaine plus corticosteroid versus intraarticular Hyaluronic acid injections…
- Conditions
- Transcutaneous, Pulsed Radiofrequency, Genicular Nerve Block, Intraarticular
- Trial name
- NCT06710782
- Testing
- Hyaluronic acid, Transcutaneous pulsed radiofrequency
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Pain, Patient Satisfaction
Effect of VR on Pain and Patient Satisfaction in Adults Receiving GNRFA
The study team aims to investigate whether implementing virtual reality therapy (VRT) during Genicular nerve radiofrequency ablation (GNRFA) procedure will provide better alleviation of procedural pain and augmented satisfaction…
- Trial name
- NCT05468398
- Testing
- Soothe VR
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Knee Osteoarthritis
High Frequency Intensive Autologous PRP Injection and Genicular Nerve Blocks in Treating Knee Osteoarthritis
Osteoarthritis (OA) of the knees is the most common degenerative disorder seen in a rehabilitation outpatient clinic. It is characterized by structural changes in the articular cartilage and the surrounding tissues.
- Trial name
- NCT04088045
- Testing
- Autologous platelet rich plasma and 5% dextrose solution injections.
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Knee Osteoarthritis
Comparison of the Efficacy of Phenol Block and Corticosteroid-Local Anesthetic Block Applied to the Genicular Nerve
There are different neurolysis methods. Aim of this study is to compare two different methods, phenol block and corticosteroid local anesthetic block.
- Trial name
- NCT06265675
- Testing
- Phenol, Celestone, Lidocain
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Osteoarthritis, Knee, Pain
Diagnostic Genicular Nerve Block Prior to Radiofrequency Ablation for Knee Osteoarthritis Pain
Chronic painful knee OA is a major cause of disability in older adults. In patients whose symptoms are refractory to conservative management but who do not wish to undergo TKA or, alternatively, are not operative candidates…
- Conditions
- Osteoarthritis, Knee, Pain, Nerve; Lesion
- Trial name
- NCT02578108
- Testing
- genicular nerve diagnostic block with lidocaine (local anesthetic), genicular nerve radiofrequency ablation
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Northwestern University
Total Knee Arthroplasty
Analgesic Effect of Adductor Canal Block, IPACK Block, and Genicular Nerve Block
Patients with total knee arthroplasty (TKA) experience severe postoperative pain. This reduces patient satisfaction, delays mobility, and prolongs hospital stay.
- Trial name
- NCT06686095
- Testing
- Group Adductor canal block, Group Genicular Nerve Block, Group IPACK Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hitit University
Juvenile Idiopathic Arthritis, Persistent Knee Arthritis
Genicular Nerve Block in Juvenile Idiopathic Arthritis
N=104 juvenile idiopathic arthritis patients diagnosed after ILAR criteria with unilateral persistent knee arthritis. They will be randomly assigned into two groups; group 1 will receive genicular nerve block, group 2…
- Conditions
- Juvenile Idiopathic Arthritis, Persistent Knee Arthritis, no Intra-articular Injection in the Last 3 Months, no Other Cause for Chronic Kneearthritis
- Trial name
- NCT04687930
- Testing
- genicular nerve block, intra-articular steroid injection
- Where
- Egypt
- Volunteers
- 104 people
- Sponsor
- Sohag University
Chronic Knee Osteoarthritis
Ultrasound-guided Radiofrequency Ablation of the Genicular Nerve Versus Physical Therapy for Chronic Knee Osteoarthritis
The aim of this study is to compare the effects of conventional physiotherapy methods with ultrasound-guided radiofrequency ablation of the genicular nerve on pain and functional status in patients with stage 2-3 chronic knee…
- Trial name
- NCT06173830
- Testing
- radiofrequency ablation, physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara City Hospital Bilkent
Knee Pain
Genicular Nerve Block for Knee Pain in the ED
Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.
- Trial name
- NCT07158736
- Testing
- Genicular nerve block with bupivacaine and corticosteroids, Standard of Care
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- University of Pennsylvania
Post Operative Pain
Comparison Between (GNB) Combined With (IPACK) Block Versus ACB in TKA
The patients will be randomized into 2 groups, named group A, B. Group A: The patients will receive Ultrasound guided Genicular nerves block combined with Ultrasound guided IPACK block.
- Trial name
- NCT06423339
- Testing
- Ultrasound guided Genicular nerve block, Interspace between the popliteal artery and the capsule of the popliteal artery and the capsule of the posterior knee, Adductor canal block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Post-operative Pain
Genicular Nerve Block for Total Knee Arthroplasty
This study seeks to examine the analgesic efficacy of genicular nerve blocks for pain after total knee replacement.
- Trial name
- NCT03706313
- Testing
- 15mL 0.25% bupivacaine, Genicular nerve block, Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Post Operative Pain Control
Evaluation of the Role of Genicular Nerve Block When Combined With Adductor Canal Block for Pain Control Following Knee Arthroscopy
The intervention tests the efficacy of Genicular nerve block when combined with Adductor canal block in comparison with Adductor canal block alone to control post operative pain in knee arthroscopy
- Trial name
- NCT06951204
- Testing
- Adductor Canal Block (ACB) Only, Adductor canal block (ACB) combined with Genicular nerve block (GNB)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Nerve Block, Regional Anaesthesia
A Comparative Study of Combined Adductor Canal and Interspace Between Popliteal Artery and Knee Capsule Versus Combined Adductor Canal and Genicular Nerve in Total Knee Arthroplasty
The aim of this study is to investigate the effectiveness of combined adductor canal block (ACB) with interspace between popliteal artery and the knee capsule (IPACK) versus combined ACB with genicular nerve block (GNB) for…
- Trial name
- NCT06864663
- Testing
- nerve block with bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Pain, Joint Function Disorder
Genicular Nerve Block in Rheuamtoid Arthritis
N=64 RA patients either early or established disease diagnosed after ACR/EULAR criteria 2010 with unilateral persistent knee arthritis.
- Conditions
- Pain, Joint Function Disorder, Inflammation
- Trial name
- NCT04361513
- Testing
- Bupivacaine hydrochloride 0.5% (Marcaine, Pfizer), triamcinolone 40 milligrams (Kenacort, Bristol Myers Squip)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Sohag University
Rupture of Anterior Cruciate Ligament
Analgesic Benefits of Genicular Nerve Blocks of the Posterior Knee for Patients Undergoing ACL Reconstruction
Outpatients scheduled to have ACL surgery typically receive a femoral nerve block to provide analgesia for the front of the knee. Postoperatively, these patients will often report pain in the back of the knee.
- Trial name
- NCT02008617
- Testing
- Bupivacaine, Preservative free normal saline
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northwestern University
Knee Osteoarthritis, Genicular Nerve Block
Phenol Neurolysis Versus Local Anesthetic Plus Steroid Genicular Nerve Block in Knee Osteoarthritis
This study aims to evaluate two different ultrasound-guided procedures for patients with knee osteoarthritis (gonarthrosis) who did not benefit from conservative treatments.
- Trial name
- NCT07267039
- Testing
- Phenol Injection, Bupivacaine + Triamcinolone Acetonide Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Salim Sencar
Postoperative Analgesia
Adductor Canal Block With IPACK Versus Genicular Nerves Block With IPACK for Post-operative Analgesia
In our study, we will find out the efficacy of those peripheral nerve blocks on postoperative pain in knee arthroscopy. The aim is to evaluate the efficacy of combined ultrasound-guided IPACK with adductor canal nerve block…
- Trial name
- IPACK (NCT07258277)
- Testing
- IPACK with adductor canal block, IPACK with Genicular nerves block, Spinal Block
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Minia University
Postoperative Pain, Knee Surgery
Comparison of Nerve Blocks for Pain Relief After Knee Surgery
This retrospective observational study compares the postoperative analgesic effectiveness of ultrasound-guided fascia iliaca compartment block (FICB) with combined IPACK and genicular nerve block (GNB) in patients undergoing knee…
- Trial name
- NCT07845591
- Testing
- Ultrasound-Guided Fascia Iliaca Compartment Block, Ultrasound-Guided Combined IPACK and Genicular Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- University of Gaziantep
Knee Osteoarthritis
Comparison of the Effect of Genicular Nerve Block and Physical Therapy in Patients With Knee Osteoarthritis
Knee arthritis is a chronic joint disease that causes pain, disability and impaired quality of life, leading to significant social and health problems worldwide.
- Trial name
- NCT06903936
- Testing
- Group 1: GNB (GENICULAR NERVOUS NERVOUS BLOCK) group:, Group 2: PT (PHYSICAL THERAPY) group, Group 3: Exercise group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ahi Evran University Education and Research Hospital