Clinical trials: Geriatric Individuals
Aging, Endothelial Dysfunction
COMP-4 Supplementation and Brachial Artery FMD
In a young and healthy person, the production of nitric oxide (NO) by the endothelium, the inner lining of the blood vessel, is responsible for a) the ability of the blood vessel to dilate so it can increase its blood flow and b)…
- Conditions
- Aging, Endothelial Dysfunction, Senescence
- Trial name
- NCT05595915
- Testing
- COMP-4
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Active Aging Individuals Aged 60 and Over, Existential Distress
Existential and Solution-Focused Group Intervention for Older Adults
This study aims to evaluate the effectiveness of an integrated existential and solution-focused group intervention enriched with narrative therapy techniques in promoting active aging among older adults.
- Trial name
- NCT07740005
- Testing
- Existential and Solution-Focused Group Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Sinop University
Aging, Parkinson's Disease (PD)
Impact of Force Control of Hip Abductor Muscles in Healthy Adults and Individuals With Parkinson's Disease
Both aging and Parkinson's disease (PD) negatively affect postural control and increase the risk of falls, with frontal plane balance being particularly challenging for these populations.
- Trial name
- NCT07568951
- Testing
- Age, Parkinson's disease (PD)
- Where
- 2 sites in Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Active Aging Individuals Aged 60 and Over
Effects of Exergame and Gross Motor-Cognitive Training in Older Adults: An RCT
Background: Aging leads to a progressive decline in gross-motor skills and executive functions, significantly increasing fall risks.
- Trial name
- NCT07701317
- Testing
- allenamento tramite Exergame, Gross motor-cognitive training
- Where
- Italy
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Muscle Mass, Protein Intake
Distribution of Nutrient Derived Amino Acids
The project examines over several days how the distribution pattern of dietary protein stimulate and affect the protein turnover of important proteins in the aging perspective, such as skeletal muscle proteins.
- Conditions
- Muscle Mass, Protein Intake, Diet Modification, Protein Synthesis
- Trial name
- NCT03870425
- Testing
- Distribution pattern of dietary proteins (minced meat)
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Vaccines, Pneumococcal Conjugate Vaccine
Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Elderly Subjects
This is a follow-up study to the core study NCT00269672 (6115A1-500). This study will further evaluate the safety, tolerability, and immunogenicity of 13-valent pneumococcal conjugate vaccine (13vPnC) when administered to…
- Trial name
- NCT00500357
- Testing
- 13-valent Pneumococcal Conjugate Vaccine
- Where
- 16 sites in South Africa
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Healthy
Effect of OPC Factor on Energy Levels
In this study the food supplement OPC Factor will be tested to determine its effectiveness for increasing energy levels in healthy people aged 45-65 when compared to a placebo.
- Trial name
- NCT00318019
- Testing
- OPC Factor(TM)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Healthy Aging, Healthy
Investigating the Effects of Daily Consumption of Blueberry (Poly)Phenols on Vascular Function and Cognitive Performance
Foods rich in certain (poly)phenols, particularly flavonoids, such as berries and cocoa, have been shown to improve measures of vascular function as well as cognitive performance in human intervention studies.
- Trial name
- BluFlow (NCT04084457)
- Testing
- Wild Blueberry powder
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- King's College London
Tetanus, Diphtheria and Acellular Pertussis Vaccination, Tetanus
Phase I/II Clinical Trial of Diphtheria-Tetanus-Pertussis (Reduced Dose) Vaccine
This is a randomized, double-blinded, parallel-controlled phase I/II clinical trial to evaluate the safety and preliminary immunogenicity of the Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (reduced…
- Conditions
- Tetanus, Diphtheria and Acellular Pertussis Vaccination, Tetanus, Diphtheria, Pertussis
- Trial name
- NCT07418372
- Testing
- low-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content), high-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content), Tetanus, Diphtheria and Acellular Pertussis Vaccine
- Where
- China
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Laser and LED Therapy on Elderly Individuals With Temporomandibular Disorder
Effects of Laser Therapy and LED Therapy on Elderly Individuals With Temporomandibular Disorder
Temporomandibular disorder (TMD) is described as a subgroup of orofacial pain with a set of signs and symptoms that involve the temporomandibular joint, masticatory muscles, ears and neck.
- Trial name
- NCT03257748
- Testing
- Laser Therapy, LED therapy
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Geriatric
Body Awareness Therapy in Geriatric Individuals: Role of Biopsychosocial Dynamics
Population aging is one of the most significant global health trends of the 21st century. As life expectancy increases, so do the physical and psychological challenges faced by older adults.
- Trial name
- Body Awareness (NCT07187076)
- Testing
- body awareness
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Muscle Strength
Comparison of the Effects of Peripheral Muscle Training and Inspiratory Muscle Training in Geriatric Individuals
In geriatric individuals, there is a decrease in muscle strength, muscle mass and physical performance with ageing. These physiological changes occurring in geriatric individuals make maintaining the physical activity necessary…
- Trial name
- NCT06321263
- Testing
- Peripheral Muscle Training and step aerobics training, Inspiratory Muscle Training and step aerobics training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biruni University
Healthy
A Study To Look At Safety And Blood Concentrations After Multiple Doses Of PF-03382792 In Healthy Elderly Individuals
This study is designed to look at the safety and blood concentrations of PF-03382792 in healthy elderly subjects after taking multiple doses for 14 days.
- Trial name
- NCT01089738
- Testing
- PF-03382792 0.5mg, PF-03382792 1.5 mg, PF-03382792 5 mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer
Sarcopenia
Sarcopenia and Intervention Physical Therapy
To evaluate and compare the effectiveness of neuromuscular electrical stimulation (NMES) and low-load resistance training with blood flow restriction (BFR) in improving muscle mass, strength, functional performance, and quality…
- Trial name
- NCT07013604
- Testing
- Neuromuscular Electrical Stimulation (NMES) Group,Resistance + BFR Group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Elderly Immune Senescence
Pilot Study to Evaluate Immunopotentiating Effects of Immulina in Elderly Individuals
This will be a small study aimed at determining the effects of oral Immulina consumption on the immune system in elderly individuals.
- Trial name
- NCT01784692
- Testing
- Immulina
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Simulation Training, High Fidelity Simulation Training
Comparison of the Effectiveness of High Fidelity Simulation and Low Fidelity Simulation in Active External Bleeding Control Management of Caregivers of Elderly Individuals
The elderly population is increasing worldwide. Due to the increase in the elderly population, emergencies related to ageing are also encountered more frequently. One of these emergencies is trauma in the elderly.
- Conditions
- Simulation Training, High Fidelity Simulation Training, First Aid, Informal Caregivers
- Trial name
- NCT06820437
- Testing
- Low-fidelity (Visually Enhanced Mental Simulation-VEMS) simulation training, High-fidelity (simulated patient/standard patient) simulation training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Non-sarcopenic Subjects, Possible Sarcopenia
Research on the Possible Relationship Between Sarcopenia and Oral Muscle Function
This study will focus on community-dwelling elderly individuals and will follow the community screening process recommended by AWGS.
- Conditions
- Non-sarcopenic Subjects, Possible Sarcopenia, Sarcopenia (With Low ASM by BIM)
- Trial name
- GSOM (NCT07658612)
- Testing
- Non interventional study
- Where
- Taiwan
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Aging, Cardiovascular Health Status
Effects of Resistance Training and Supplementation in Elderly: Cardiorespiratory and Metabolic Variables
Aging causes losses in strength, lean mass, and cardiovascular health in the elderly due to metabolic changes and alterations in body composition.
- Conditions
- Aging, Cardiovascular Health Status, Physical Training, Nutritional Interventions
- Trial name
- NCT06682221
- Testing
- Whey protein supplementation., Resistance training, Group Control
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Vascular Stiffness, Vasodilation
Effects of Betalains on Cardiovascular Health and Quality of Life
The goal of this randomized, double-blind, placebo-controlled, cross-over trial is to investigate the effects of beetroot-derived betalains on cardiovascular health, sleep and quality of life in healthy middle-aged individuals.
- Conditions
- Vascular Stiffness, Vasodilation, Sleep, Quality of Life
- Trial name
- NCT06117007
- Testing
- Betalains
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- King's College London
Avoidant/Restrictive Food Intake Disorder (ARFID)
Cognitive Behavioural Therapy for Avoidant/Restrictive Food Intake Disorder (CBT-AR)
CBT-AR describes an adaption of cognitive behavioural therapy for use with individuals diagnosed with Avoidant/Restrictive Food Intake Disorder (ARFID).
- Trial name
- CBT-AR (NCT06463470)
- Testing
- Cognitive Behavioural Therapy for Avoidant/Restrictive Food Intake Disorder (CBT-AR)
- Where
- 2 sites in Australia
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Orygen