Clinical trials: Gingival Condition
Periodontal Disease
Endocan, VEGF and TNF-alpha Levels in Periodontal Disease and After Treatment
The primer aim of the study was to determine serum and gingival crevicular fluid (GCF) endocan levels in periodontal diseases pathogenesis supported with vascular endothelial growth factor (VEGF) and tumor necrosis factor alpha…
- Trial name
- NCT02750956
- Testing
- Non-surgical periodontal treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Cross-linked Hyaluronic Acid
Treatment of Buccal Ginvigal Recessions With the Tunnel Technique in Conjunction With Cross-linked Hyaluronic Acid and Subepithelial Connective Tissue Graft. A Randomized Clinical Trial
To evaluate the outcomes of buccal gengival recession type 1 (RT1) treated with the tunnel technique in conjunction with a cross-linked hyaluronic acid and subepithelial palatal connective tissue grafts.
- Trial name
- NCT05436002
- Testing
- With Cross-linked Hyaluronic Acid
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Pericoronitis
Effect of Oxyflower® Gel as a Coadjuvant in Pericoronitis Treatment
The objective of this study is to evaluate the clinical effect and the impact on the quality of life of the coadjuvant treatment with Oxyflower® gel in cases of pericoronitis in lower third molar, compared to chlorhexidine gel…
- Trial name
- NCT03919942
- Testing
- OxyFlower gel, Chlorhexidine gel
- Where
- Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Periodontitis, Gingivitis
Evaluation of PTHrP, RANKL, and OPG Levels in Periodontal Health and Diseases
This observational study aims to evaluate the levels of specific biological markers-Parathyroid Hormone-Related Protein (PTHrP), RANKL, and Osteoprotegerin (OPG)-in the gingival crevicular fluid of individuals with different gum…
- Conditions
- Periodontitis, Gingivitis, Periodontal Disease
- Trial name
- NCT07793370
- Testing
- Routine periodontal clinical examination and GCF collection
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Periodontal Disease, Postmenopausal Osteoporosis (PMO)
Relationship Between Periodontal Disease and Postmenopausal Osteoporosis
Elevated sclerostin levels in serum and alveolar bone of osteoporotic patients may exert deleterious effects on the periodontium, thereby contributing to the progression and increased severity of periodontal disease.
- Trial name
- NCT07294105
- Testing
- clinical assessment, Radiographic Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Gingival Recession
Comparison of Two Techniques in Gingival Recession Treatment. One-year Clinical Follow-up Study
42 patients were treated either with E-CTG (N=20) or SCAF (N=22). The recordings included clinician-based (recession depth, recession width, probing depth, clinical attachment level, keratinized tissue width, tissue thickness…
- Trial name
- NCT04109794
- Testing
- E-CTG
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Gingival Displacement
Evaluation of Gingival Displacement Methods
This clinical study is being conducted to compare four different methods used to temporarily push the gums away from the teeth during dental procedures.
- Trial name
- NCT07122297
- Testing
- Retraction cord, Retraction paste in capsule form, Retraction paste in injector form
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Habituation
The Effects of Chewing Gum on a Computer Task and Liking Ratings of Ice Cream
The purpose of this study is to examine if chewing gum before an eating bout will increase the rate of habituation and subsequently reduce energy intake within the eating bout.
- Trial name
- NCT02198911
- Testing
- NO GUM, MCC (Mint Chocolate Chip gum), C (Cinnamon gum)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Postoperative Pain, Postoperative Complications
Patient Morbidity After Palatal Free Gingival Grafts With or Without PRF Membranes Coverage
This study evaluates postoperative morbidity of patients that undergo free gingival graft harvesting from palate with or without use of autogenous PRF (Platelet Rich Fibrin) membranes to cover the donor site.In the Test Group…
- Conditions
- Postoperative Pain, Postoperative Complications, Gingival Recession
- Trial name
- NCT03685396
- Testing
- Platelet rich fibrin ( PRF), hemostatic agents with oxidized and regenerated cellulosa
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera San Paolo
Gingivitis
A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods
Subjects who have shown evidence of gingivitis and plaque will be enrolled in this study. Each subject will be randomly assigned to one of two treatment products.
- Trial name
- NCT07211061
- Testing
- Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice, electric toothbrush
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Preterm Labor, Periodontitis
Inflammatory Cytokines in GCF and Placental Tissues in Chronic Periodontitis Patients With Preterm Delivery
Investigators have shown the presence of elevated proinflammatory cytokines in amniotic fluid in patients in preterm labor.However, there is limited and mostly negative evidence that the elevation of these mediators in gingival…
- Trial name
- NCT02521688
- Testing
- incisional biopsy from placenta and GCF sample
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gingivitis
Comparisons Of Different Antiplaque Agents On Gingivitis In Orthodontic Patients
Fixed orthodontic treatment affects the periodontium by allowing plaque accumulation on teeth if the oral ecosystem is unfavorable which initially causes gingivitis to progress into periodontitis, and later enamel…
- Trial name
- NCT06305546
- Testing
- Chlorhexidine Gluconate, Metronidazole, combination gel (chlorhexidine and metronidazole)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Anam Sattar
Periodontal Diseases, Gingivitis
Comparative Evaluation of Antiplaque and Antigingivitis Efficacy of Ocimum Sanctum (Tulsi) Extract
Chlorhexidine is considered as gold standard for its antiplaque and antigingivitis efficacy till date but it has got many side effects.
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis
- Trial name
- NCT03474146
- Testing
- Ocimum sanctum, Chlorhexidine Gluconate, Propylene Glycol
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government College of Dentistry, Indore
Gingivitis, Dental Plaque
"Safeguard Your Smile" an Oral Health Literacy Intervention Promoting Positive Oral Hygiene Self-care Behavior
The purpose of the investigators' study is to assess effectiveness of community based oral health literacy intervention promoting positive oral hygiene self-care behavior among Montreal's Punjabi immigrants.
- Trial name
- NCT02521155
- Testing
- Safeguard Your Smile an oral health literacy intervention
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Modified Free Gingival Graft , Connective Tissue Graft
Efficacy of the Modified Free Gingival Graft Technique
Gingival recessions can be defined as the exposure of the root surface after an apical migration of the gingival margin in relation to the cemento-enamel junction. Gingival recessions affect both younger and older populations.
- Trial name
- FGG (NCT06580821)
- Testing
- mucogingigval surgery
- Where
- Ecuador
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Gingival Recession
Xenogeneic Collagen Matrix or Palatal Connective Tissue Graft With a Coronally Advanced Flap in Class III Recessions
The purpose of this multi-center study is to compare the effectiveness of Mucograft versus connective tissue graft in combination with coronal advanced flap for the treatment of Miller class III recessions The connective tissue…
- Trial name
- NCT03344315
- Testing
- experimental: collagen matrix, Active Comparator: autologous connective tissue graft
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Peri-Implantitis, Peri-implant Mucositis
Peri-implant Conditions Mimic Periodontal Conditions
Except for patients with referred clinical bruxism and uncontrolled medical conditions, the study included 123 implants with implanted fixed prostheses that had lasted at least six months after functional prosthetic loading.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Peri-implant Health, Periodontitis
- Trial name
- NCT06128850
- Testing
- disease
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Inflammation, Periodontal Disease
Correlation Between Oral Health and Systemic Inflammation (COHESION)
COHESION is a randomized trial targeting reduction of systemic inflammation through an oral hygiene regimen incorporating a plaque-disclosing toothpaste and a control toothpaste.
- Conditions
- Inflammation, Periodontal Disease, Gingivitis
- Trial name
- COHESION (NCT03641989)
- Testing
- Plaque disclosing toothpaste, Non-plaque disclosing toothpaste
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Marshfield Clinic Research Foundation
Halitosis, Mouth Disease
Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.
The aim of the study: To assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah…
- Conditions
- Halitosis, Mouth Disease, Plaque Induced Gingival Disease, Bleeding Gum
- Trial name
- NCT06882564
- Testing
- resveratrol mouthwash, Chlorhexidine mouthwash (0.2%)
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Gingival Recession
Treatment of Miller Class I and II Gingival Recession Using Non- Pedicled Buccal Fat Pad Graft as Compared to Subepithelial Connective Tissue Graft
This randomized controlled single blinded parallel clinical trial is held to monitor if the use of the non pedicled buccal fat pad graft will result in post operative pain as a primary outcome compared to that occurs with the use…
- Trial name
- NCT03543163
- Testing
- Non- Pedicled Buccal Fat Pad with Coronally Advanced flap, sub-epithelial connective tissue graft
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
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