Clinical trials: Heat
Physiological Stress
Evaluating the Physiological Strain Induced by a BC Protective Undergarment Under Exercise-heat Stress
Israel ministry of defense is examining a new protective undergarment of GORE company (chempark fabric) for the police forces. The goal of this research is to perform a comparative experiment in order to evaluate the…
- Trial name
- NCT02463058
- Testing
- exercise under hot and humid conditions protocol
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Enteral Nutrition, Gastrointestinal System--Abnormalities
Heat Application on Gastrointestinal System Functions
Complications related to the gastrointestinal system can occur in patients receiving enteral nutrition. These complications may include nausea, vomiting, diarrhea, constipation, decreased bowel sounds, abdominal distension…
- Trial name
- NCT06225687
- Testing
- Heat Application
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Physical Activity Attitude, Health Behavior
Trust in Institutions, Environment, and Physical Activity
Trust is the willingness of people to cooperate. Although much research has been conducted on physical activity, little research has explored trust in institutions regarding environmental and physical activity recommendations.
- Conditions
- Physical Activity Attitude, Health Behavior, Trust
- Trial name
- TrustAndMove (NCT07472569)
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Polio
Evaluation of Safety, Reactogenicity and Immunogenicity of Fractional-dose Inactivated Polio Vaccine (fIPV) Given Intradermally With Double Mutant Enterotoxigenic Escherichia Coli Heat Labile Toxin (dmLT) Adjuvant
Polio is a serious disease that can cause paralysis and death. It is caused by a virus and can be prevented by vaccine. The World Health Organization's (WHO) Global Polio Eradication Initiative is trying to get rid of all polio…
- Trial name
- NCT03922061
- Testing
- dmLT, fIPV
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Exertional Heat Illness
Comparing Exertional Heat Illness Risk Factors Between Patients and Controls
The arduous nature of military training and operations require personnel to encounter high heat load, e.g., during intense physical exertion, particularly in the heat.
- Trial name
- NCT05303142
- Testing
- Heat Tolerance Assessment
- Where
- United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Hyperthermia
Semiconductor Heat Extraction Cooling
Heat-related injuries and other physiological stresses continue to be a significant threat to the health and operational effectiveness of the US Armed Forces (Armed Forces Health Surveillance 2011).
- Trial name
- SHE-Cool (NCT04915859)
- Testing
- Hand Cooling at 12-15 degrees celsius, Hand Cooling at 16-20 degrees celsius, hand and back cooling at 12-15 or 16-20 degrees celsius
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Heart Rate, All-day Steps
Assessing the Effect of Cool Roofs on Health Using Smartwatches
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate…
- Conditions
- Heart Rate, All-day Steps, Distance Walked, Active Minutes
- Trial name
- REFLECT (NCT06579963)
- Testing
- Cool roof
- Where
- 4 sites in Burkina Faso, India and 2 more
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Menopause, Menopause Related Conditions
Hot Water Therapy for the Treatment of Menopause-related Hot Flashes
The purpose of this research is to determine whether hot water therapy (i.e. taking prolonged hot baths on multiple consecutive days) decreases hot flash symptoms and improves mood in women who are undergoing or who have…
- Conditions
- Menopause, Menopause Related Conditions, Menopause Syndrome
- Trial name
- NCT06192329
- Testing
- Hot water therapy, Warm water immersion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Muscle Damage
Heat Therapy to Accelerate Muscle Recovery
The use of cold on muscle (Ice, Cold Water Immersion - CWI or cryotherapy) is a widespread practice used by health professionals, athletes or non-athletic population in the treatment of muscle soreness and soft tissue injuries.
- Trial name
- NCT05506514
- Testing
- Water immersion
- Where
- Qatar
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Aspetar
Peer Review, Research
Transdermal Patch CVD 2000: The Effect of Heat on Fentanyl Release From Fentanyl TDSs in Healthy Adults
This is an Open-label, Non-Randomized, 3-way Crossover Bioequivalence Study to compare fentanyl release after heating of a brand name (Duragesic) and generic (Apotex and Mylan) fentanyl (transdermal delivery system)TDSs in…
- Trial name
- NCT02486016
- Testing
- Duragesic reference fentanyl TDS, Apotex generic fentanyl TDS, Mylan generic fentanyl TDS
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Heat Transfer by Clinical Warming Devices
Heat Loss in Humans Covered With Full-Body Blankets Connected to Different Warming Devices
The investigators propose a single-center multiple crossover randomized trial to determine the efficacy of four warming devices and five warming blankets.
- Trial name
- NCT06198959
- Testing
- Adult blanket plus, MA2220 blanket connected to the Mistral Air, Blower MA1200-PM system., Premium adult blanket, 3320 blanket connected to the Mistral Air, Blower MA1200-PM system., Blanket full body, 30000 blanket connected to the 3M, Bair Hugger, Blower 775
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Neonatal Adaptation
Polyethylene Body Bags as an Alternative to Radiant Heat Lamp During the Neonatal Adaptation in Infants Older Than 29 Weeks
INTRODUCTION: Hypothermia in the newborn causes morbid conditions. In developing countries in the basic technology for neonatal adaptation may not be available.
- Trial name
- NCT02250079
- Testing
- polyethylene plastic bag, Conventional treatment
- Where
- Colombia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Frailty, Dementia
HEalthy Aging Team Supported Home-care Services (HEAT-YASAM)
Depending on the YASAM project which was established to home-visit evaluate community-dwelling older adults (80 years of age and over), we aimed to determine the prevalence (prevalence) of geriatric syndromes (dependence…
- Conditions
- Frailty, Dementia, Depression, Malnutrition
- Trial name
- HEAT-YASAM (NCT05993572)
- Testing
- Comprehensive Geriatric Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Dehydration
Post-exercise Rehydration: A Randomised Cross-over Trial Comparing a 100% Fruit Beverage, a Glucose-based Sports Drink, and Water
It is well-established that exercise has many health benefits. During exercise in temperate/hot conditions, sweating is necessary to dissipate heat.
- Trial name
- NCT07468539
- Testing
- Water, Glucose-based sports drink, Fruit beverage
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Body Temperature Regulation
Physiological and Molecular Influences of Astaxanthin Supplementation on Heat Strain in Humans
Exposure to heat stress can compromise the physiological and cognitive function and be life threatening, particularly in a military setting.
- Trial name
- Astaxanthin (NCT02088242)
- Testing
- Astaxanthin
- Where
- Israel
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Radial Artery
Radial Artery Vasodilation Heat Study
The purpose of this study is to collect data about the efficacy of utilizing distal topical heat application for dilatation of the radial artery.
- Trial name
- NCT03620383
- Testing
- Topical Heat
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Diarrhea, Upper Respiratory Infections
Children Immune Functions
The purpose of the planned study is to investigate the effect of heat-treated lactobacilli on diarrhea outcome in healthy children 1-4 years old in a randomized, double-blind, placebo-controlled study.
- Trial name
- NCT01717534
- Where
- 2 sites in Mexico
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Heat Acclimation and Thermotolerance
Effect of Combined Exercise, Heat, and Quercetin Supplementation on Whole Body Stress Response
The purpose of this study is to determine whether dietary quercetin supplementation effects thermotolerance and heat acclimation in human subjects exposed to exercise/heat stress. Specific Aim I.
- Trial name
- NCT01168739
- Testing
- Quercetin
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Dehydration (Physiology), Hyperthermia
Water Bolus Volumes During Continuous Exercise in Heat
Hydration is important to all individuals including occupational workers who complete physical activity in the heat. Current best practice guidelines suggest drinking a cup of water every 15-20 minutes during activity in a hot…
- Trial name
- NCT04613856
- Testing
- Hydration protocol - 237 mL water bolus, Hydration protocol - 500 mL water bolus
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Depression, Selective Serotonin Reuptake Inhibitor
Impact of Depression on Thermoregulation
The purpose of this study is to determine if, compared to non-depressed adults, differences exist in skin blood flow and sweating responses to passive heat stress in adults with clinically diagnosed depression, those with…
- Trial name
- NCT06805851
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Penn State University