Clinical trials: Heat Effect
Tetraplegia, Hypothermia
Effect of Heat Exposure on Cognition in Persons With Tetraplegia
The ability to maintain normal body temperature (Tcore) is impaired in persons with tetraplegia: subnormal Tcore and vulnerability to hypothermia (<95 F) have been documented in this population after exposure to even mild…
- Conditions
- Tetraplegia, Hypothermia, Mild Cognitive Impairment
- Trial name
- NCT02488824
- Testing
- Warm Temperature
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Muscle Disorder
Stretching Exercises Versus Thermotherapy on Restless Legs Syndrome Symptoms
To compare the effects of stretching exercises versus thermotherapy on RLS symptoms and sleep quality among pregnant women. Research hypotheses: Pregnant women who perform leg stretching exercises exhibit lower RLS symptoms…
- Trial name
- Exersize (NCT05261035)
- Testing
- stretching exercises, thermotherapy
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Central Sensitisation
Differences in Pain Processing Between Men and Women
Many chronic pain conditions show clear differences between between men and women, such as reported pain intensities or treatment effects, with chronic pain conditions being generally more frequent in women.
- Trial name
- NCT05031286
- Testing
- Cutaneous thermal stimuli
- Where
- Switzerland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Capsaicin Evoked Pain, Heat Sensitivity
Study to Investigate the Effects Single Oral Dose of AZD1386 (Capsaicin)
A double-blind, randomized, single-centre, placebo-controlled, crossover study to investigate the effects of a single oral dose of AZD1386 on intradermal capsaicin evoked pain symptoms and heat sensitivity in healthy volunteers
- Trial name
- NCT00692146
- Testing
- AZD1386
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Effects of Heat, Tolerability
Evaluation of Experimental Heat Patch
A disposable, air-activated, adhesive backed heat patch is being developed to provide temporary relief from minor muscular ache and joint pains associated with overexertion strains and sprains as well as minor pain associated…
- Conditions
- Effects of Heat, Tolerability, Adhesiveness, Dermal Irritation
- Trial name
- NCT01841788
- Testing
- Thermal Adhesion Patch, Marketed Thermal Adhesion Patch
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chattem, Inc.
Heat Stress, Heat Strain
Effects of Solar Radiation on Human Function and Cognition
Solar radiation is a physical phenomenon which interacts with any human being throughout its life on earth. This interaction is associated with numerous physiological functions, as well as a broad spectrum of deleterious effects…
- Trial name
- NCT04160741
- Testing
- Radiation and warm environment, Warm environment, Neutral environment with radiation
- Where
- Greece
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Petros Dinas
Sleep Quality
Mitigation of Health Effects in Pregnant Women by Reducing Exposure to Heat and Air Pollution
The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health…
- Trial name
- ISMED CLIM PW (NCT07609433)
- Testing
- Heat intervention, Heat and air pollution mitigation intervention
- Where
- 3 sites in Cyprus, Italy
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Metabolism Changes, Vitamin D
Does Vitamin C Increase the Body Heat Generated By The Nervous System?
The goals of this clinical trial are to determine whether or not vitamin C is able to: (1) increase the body heat generated by the sympathetic nervous system; and, (2) increase circulating vitamin D concentration during…
- Trial name
- NCT07341308
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Psoriasis
Chinese Herbal Medicine for Psoriasis Vulgaris: a Real World Study
The purpose of this study is to establish a multi-center clinical registration platform, to form the real world evidence of New Blood Syndrome Theory intervention in psoriasis, and to evaluate the therapeutic advantages of New…
- Trial name
- NCT03942185
- Testing
- Oral Chinese Herbal Medicine of Clearing heat and Cooling blood therapy, Oral Chinese Herbal Medicine according with syndrome differentiation therapy, Oral Chinese Herbal Medicine of Promoting blood circulation and Removing blood stasis therapy
- Where
- 20 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Wound Heal, Pain, Postoperative
Dry Heat Versus Sitz Bath On Episiotomy Wound Heating And Pelvic Pain
Objective: To compare the effect of dry heat versus moist heat application on episiotomy wound healing and pain among postnatal mothers.
- Trial name
- Dry_Heat (NCT05186532)
- Testing
- Dry Heat Application, Moist Heat Application
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Secondary Hyperalgesia, Inflammation
The Effect of Hyperbaric Oxygen Therapy on Inflammatory Parameters Induced by a Heat Injury Model
Hyperbaric oxygen may reduce neurophatic pain and promote wound healing. Established anti inflammatory effects of HBO may contribute to this effect.
- Trial name
- HBO-SHA (NCT02397343)
- Testing
- Hyperbaric oxygen
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hyperthermia, Fatigue; Heat
Work Design Interventions for Older Workers During Consecutive Days in the Heat
The goal of this project is to compare different ways to schedule a workday to see if older workers should follow a specific work protocol to reduce strain on the heart and muscles across two consecutive days of work.
- Conditions
- Hyperthermia, Fatigue; Heat, Work-Related Condition
- Trial name
- NCT07046026
- Testing
- Standard work pace, Additional rest breaks
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Sexual Dysfunction, Physiological
Vaginal Heat Wash-out (HWO) in 4 Groups of Women (Pre- and Postmenopausal With and Without Female Sexual Arousal Disorder (FSAD)).
The Pfizer developed Heat Wash-Out (HWO) system is a software controlled electromechanical system designed to measure vaginal wall blood flow. A small vaginal probe is attached to a control unit.
- Trial name
- FSAD HWO VBF (NCT00443248)
- Testing
- Vaginal Heat Wash-Out Device
- Where
- 2 sites in Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pfizer
Neonatal Pain, Non-Pharmacological Pain Management
Effect of Two Non-pharmacological Method on Pain, Stress Procedure Duration in Newborn
This study is planned as a prospective, single-blind, randomized controlled experimental study matched according to gestational age, gender, and birth weight, to determine the effects of local heat application and oral sucrose…
- Trial name
- NCT07125690
- Testing
- local heat application, oral sucrose, mixed group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
DYSMENORRHEA
Heat Application on Depression, Anxiety, Menstrual Attitude and Dysmenorrhea
AIM: Establishing the effects of heat application on depression, anxiety, menstrual attitude and severity of dysmenorrhea. METHODS: This randomized controlled prospective experimental trial was conducted with 43 students who were…
- Trial name
- NCT04572555
- Testing
- Heat Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Heat Stress, Diet Induced Thermogenesis
Carbohydrate or Protein Drinks Before Exercise in the Heat
This project examines whether consuming a high-protein or high-carbohydrate beverage before exercise in the heat impacts metabolism and heat balance during exercise, with the following research questions: 1.
- Conditions
- Heat Stress, Diet Induced Thermogenesis, Protein Consumption
- Trial name
- NCT07646990
- Testing
- Protein shake, Carbohydrate shake
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Providence College
HIV Infections
Feasibility and Pilot Efficacy of Flash-heated Breast Milk to Reduce Maternal-to-Child-Transmission of HIV in Tanzania
This study will investigate the feasibility of HIV positive mothers in Tanzania to correctly use the Flash-heat method to pasteurize their breast milk and for how long they are able to do so.
- Trial name
- Flash-heat (NCT00523510)
- Testing
- Infant feeding counseling that includes Flash-heat
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Eating Habit, Cold Exposure
Assessment of the Effects of a 24-hour Cold and Heat Exposure on the Factors Influencing Food Intake
Military personnel and athletes have a very high energy expenditure which is increased during certain key periods (intense training, competition and mission).
- Conditions
- Eating Habit, Cold Exposure, Heat
- Trial name
- TEMPCA (NCT05584527)
- Testing
- Heat exposure (32°C), Cold exposure (16°C), Thermoneutral exposure (24°C)
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Heat Stress, Heat Exposure
Validity of Humidity Ramp Protocols for Identifying Limits of Survivability in Heat-exposed Persons
The global populace is at growing risk of heat-related illness due to climate change and accompanying increases in the intensity and regularity of extremely hot temperatures.
- Conditions
- Heat Stress, Heat Exposure, Temperature Change, Body, Temperature; Extreme, Exposure
- Trial name
- NCT05963529
- Testing
- Humidity-ramp protocol, Above-inflection fixed-condition exposure, Below-inflection fixed-condition exposure
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Heat Stress, Physiological Stress
Influence of Indoor Humidity on Physiological Strain in Older Adults During a Simulated Heat Wave
Laboratory-based studies show that exposure to high humidity can worsen the effects of heat stress in young and older adults by impeding sweat evaporation - the main mechanism by which the human body cools itself.
- Trial name
- NCT06842953
- Testing
- Simulated indoor overheating
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa