Clinical trials: Hemodynamic Responses
Intubation, Anesthesia
The Effect of Video and Traditional Laryngoscopy on Hemodynamic Response in Hypertensive and Normotensive Patients
During endotracheal intubation, it is known that la laryngoscopy has significant effects, such as tachycardia and blood pressure increase, which may be harmful, especially in those with cardiovascular disease.
- Conditions
- Intubation, Anesthesia, Hypertension
- Trial name
- Laryngoscopy (NCT03376828)
- Testing
- Macintosh laryngoscopy, C-Mac Videolaryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Hypertension, Cardiovascular Risk Factor
Central Arterial Hemodynamics and Resistance Training
Resistance exercise training is one of the popular exercise modes that has been drawn the public's attention. However, existing evidence showed high-intensity resistance exercise training-induced negative adaptation on vascular…
- Trial name
- NCT04546308
- Testing
- Resistance exercise training
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Fatigue, Muscle
Feasibility Study of a Neuromuscular Fatigue Test and Associated Hemodynamic Responses: Application in Healthy Volunteers for Use in Patients with Chemotherapy-treated Breast Cancer
This cross-sectional and single-center study aims to progressively induce an increase in peripheral fatigue during successive efforts in healthy subjects.
- Conditions
- Fatigue, Muscle, Heart
- Trial name
- PROTECT-08A (NCT06775119)
- Testing
- Test of neuromuscular fatigue and associated hemodynamic responses
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut de cancérologie Strasbourg Europe
Hemodynamic Response to Laryngoscopy and Orotracheal Intubation
Effect of Nalbuphine on Hemodynamic Response During Laryngoscopy and Intubation
Laryngoscopy and placement of a breathing tube during general anesthesia can cause temporary increases in blood pressure and heart rate. These changes may be harmful in some patients.
- Trial name
- NAL-HRI (NCT07348159)
- Testing
- Normal saline IV, Nalbuphine 0.2 mg/kg
- Where
- Pakistan
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Dr. Waseem Ullah
Obesity Adult Onset
Effects of Chronic Dietary Grape Seed Extract Supplementation on Aortic Stiffness and Hemodynamic Responses to Exercise in Obese Males
It was demonstrated that acute dietary supplementation with GSE reduced arterial blood pressure via reduction in Q in obese individuals.
- Trial name
- NCT04465110
- Testing
- Grape Seed Extract
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- California Baptist University
Hypertension
Hemodynamic Effects of Aliskiren Compared to Captopril on the Kidney in Healthy Volunteers on a Low- and High- Sodium Diet
This study will measure the effects of different doses of aliskiren on kidney blood flow and function in healthy adults and determine how salt intake affects the response to aliskiren.
- Trial name
- NCT00518765
- Testing
- Aliskiren
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novartis
Healthy, Heart Failure
The Hemodynamic Response to Prolonged Dobutamine Infusion
A decrease in the response of beta 1 adrenergic receptors to agonists (desensitization) is thought to play a major role in the pathogenesis of diseases such as congestive heart failure.
- Trial name
- NCT01042873
- Testing
- 3 hours intravenous dobutamine
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Healthy
Hemodynamic Responses During Induction: Comparison of Marsh and Schnider Pharmacokinetic Models
To compare the hemodynamic changes during anesthesia induction between Marsh and Schnider plasma TCI models. We put forward a hypothesis that, if one TCI model is associated with much more prominent vasodilation effect or cardiac…
- Trial name
- TCI (NCT01759160)
- Testing
- Marsh Plasma TCI with high initial target, Schnider Plasma TCI with high initial target
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Autonomic Nervous System Disease
Resonance Breathing and Postural Resonance: Acute Modulation of Autonomic and Hemodynamic Responses Via Arterial Baroreflex Mechanisms
This randomized crossover study compared the acute autonomic and hemodynamic responses to three experimental conditions: control, resonance breathing (RB), and postural resonance (PR), in healthy young adults.
- Trial name
- Autonomic (NCT07536997)
- Testing
- Resonance Breathing, Postural Resonance
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Mild Cognitive Impairment, Mild Dementia
Resistance Training to Individuals for Cognitive Impairment With Dementia
This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function…
- Trial name
- TRAIN4BRAIN (NCT06185010)
- Testing
- One Resistance Training Set (Single Session), Three Resistance Training Sets (Single Session), One Resistance Training Set (8 Weeks)
- Where
- Portugal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Beira Interior
Heart Failure, Congestive
Hemodynamic Response to Exercise in HFpEF Patients After Upregulation of SERCA2a
Heart failure with preserved ejection fraction or HFpEF, represents nearly 50% of all heart failure cases and is particularly common in the elderly. The disease has no current treatment options.
- Trial name
- NCT02772068
- Testing
- Istaroxime, Exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Benjamin Levine
Hemodynamic Responses to Propofol
Hemodynamic Changes After Anesthesia With Propofol: Study of Biomarkers
The purpose of this study is to evaluate biomarkers affecting the hemodynamic responses to propofol. Particularly, the investigators will assess the effects of polymorphisms in NOS3 and PRKCA genes on hemodynamic responses to…
- Trial name
- NCT02442232
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
Anxiety, Hypotension
Impact of Music on Satisfaction, Anxiety, and Hemodynamics During Spinal Anesthesia for Cesarean Delivery
The aim of this study is to evaluate the effect of perioperative music on maternal anxiety, hemodynamic response to spinal anesthesia, postoperative pain medication requirement, and overall maternal satisfaction.
- Trial name
- NCT02732964
- Testing
- Pandora Music, Mozart Music
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Analgesic Effects, Systemic Stress Response
Bilateral Ultrasound Guided Pectoralis Nerve Block Induces Hemodynamic Stability With Reducing Systemic Stress Response for Off-pump Coronary Artery Bypass Graft
Opioids used in attenuation of the neuroendocrine stress response in patients undergoing off-pump coronary artery bypass graft (OPCAB) it produces predictable satisfactory analgesia and sedation but with side effects such as…
- Conditions
- Analgesic Effects, Systemic Stress Response, Hemodynamic Stability
- Trial name
- NCT03734848
- Testing
- Bilateral Ultrasound Guided Pectoralis Nerve Block.
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Forward Head Posture, Normal Head Posture
Comparison of Prefrontal Hemodynamic Responses and Balance Control Differences Based on Head Posture and Task Difficulty in Cognitive-Balance Tasks
Recent studies have shown that individuals with forward head posture (FHP) experience not only impaired balance control but also cognitive deficits.
- Trial name
- NCT06850077
- Testing
- Cognitive-Balance dual task
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Sahmyook University
Intracranial Pressure Increase, Supraglottic Airway Device
Effect of Different Supralottic Airway Devicess on Optic Nerve Sheath Diameter
Direct laryngoscopy and tracheal intubation are associated with increases in intraocular pressure (IOP), intracranial pressure (ICP), heart rate (HR), and blood pressure.
- Conditions
- Intracranial Pressure Increase, Supraglottic Airway Device, Optic Nerve Sheath Diameter
- Trial name
- NCT05499754
- Testing
- pLMA: PROSEAL LARYNGEAL MASK, sLMA : SUPREMA LARYNGEAL MASK, I-jel =I-GEL
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Prefrontal Hemodynamics, Muscle Strength
Lower Limb Strength and Power as Predictors of Brain Blood Flow During Exercise
This study aims to investigate the predictive value of lower limb muscle strength and explosive power on exercise-induced prefrontal hemodynamic responses.
- Conditions
- Prefrontal Hemodynamics, Muscle Strength, Physical Performance
- Trial name
- LLSPP (NCT07575802)
- Testing
- Standardized Lower-Limb Physical Performance Assessment and Aerobic Exercise Task
- Where
- Russia
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Hemodynamic Instability
Comparision Between Hemodynamic Response of Dexmedetomidine and Remifentanil on Anesthesia in Endoscopic Sinus Surgery
During endoscopic sinus surgery (ESS), epinephrine local injection and controlled hypotension is essential in order to increase the visibility in the operative field and reduce the risk.
- Trial name
- NCT02464722
- Testing
- Dexmedetomidine, Remifentanil, Epinephrine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Laryngoscopic Stress Response, Video Laryngoscopy
Effect of Video Laryngoscopy Versus Conventional Laryngoscopy Upon Hemodynamics
In general anestheisa airway is secured by passing a tube down the widpipe. This helps the patient to breath via ventilator during anesthesia.
- Conditions
- Laryngoscopic Stress Response, Video Laryngoscopy, Conventional Laryngoscopy
- Trial name
- NCT07300878
- Testing
- C MAC hyperangulated video laryngoscopy, Conventional macintosh laryngoscopy
- Where
- Pakistan
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Erectile Dysfunction
Study to Evaluate Hemodynamic Response to to a Sublingual Dose of Glyceryl Trinitrate in Subjects Receiving TA-1790, Sildenafil Citrate, and Placebo
The objective of this study is to evaluate the hemodynamic response to a sublingual dose of glyceryl trinitrate in subjects receiving oral TA-1790, sildenafil citrate, and placebo.
- Trial name
- NCT01616485
- Testing
- TA-1790, Sildenafil citrate, Nitrostat
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC