Clinical trials: Image Quality
Aortic Aneurysm, Contrast Induced Nephropathy
Computed Tomography Arteriograms (CTA) Volume Dose Reduction Study
The purpose of the study is to determine if the dose of contrast (Omnipaque) administered for Computed Tomography Arteriograms (CTA) can be reduced without degradation of image quality.
- Conditions
- Aortic Aneurysm, Contrast Induced Nephropathy, Aortic and Arterial Anomalies
- Trial name
- NCT02669784
- Testing
- Low Dose Contrast (Omnipaque) 40mL, Low Dose Contrast (Omnipaque) 50 mL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Milton S. Hershey Medical Center
Brain Imaging, Whole Body Imaging
Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction
The purpose of this study is to assess the effectiveness of new software available on a new PET/CT scanner in the Molecular Imaging Research PET/CT Facility.
- Trial name
- NCT04417998
- Testing
- 18F-FDG, 18F-AV1451, Siemens E7 Reconstruction Tool
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Cancer Stage
Clinical Evaluation of Opto-Acoustic Image Quality With the Gen 2 Imagio System
This study performs the first clinical evaluation of the Gen 2 Imagio System in a clinical setting to assess image quality with both the IUS ultrasound only probe and the OA/US (duplex probe).
- Trial name
- NCT05022602
- Testing
- Imagio
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Seno Medical Instruments Inc.
Capsule Endoscopy
The Second-Generation MCCG for Upper Gastrointestinal Tract.
The aim of this study is to evaluate the clinical application of the second-generation MCCG with higher image resolution and frame rate for upper gastrointestinal tract compared with the first-generation.
- Trial name
- NCT03977935
- Testing
- the second-generation MCCG
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Computed Tomography, Radiation Dosage
Breast Displacement and CT Radiation Dose
The primary hypothesis of this study is that breast displacement out of the direct plane of imaging during computed tomography (CT) of the abdomen will reduce effective radiation dose to the female breast.
- Trial name
- Chrysalis (NCT01261559)
- Testing
- Chrysalis breast displacement device
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Washington
Breast Health
Image Quality Assessment for Screening and Diagnostic Mammography
This study is being conducted to determine the image quality of images using a new investigational medical imaging device.
- Trial name
- NCT02786004
- Testing
- Full Field Digital Mammography, Digital Breast Tomosynthesis
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- GE Healthcare
Healthy
A Healthy Volunteer Trial Investigating MR-enterography Image Quality of Lumentin® 44
A healthy volunteer, open, PoC single center trial investigating a new oral contrast agent for use in combination of MR examination of the abdomen and pelvis.
- Trial name
- NCT05781490
- Testing
- Lumentin® 44 Powder for oral foam
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lument AB
Prostate Cancer, Head and Neck Cancers
A Pilot Study Evaluating the Effect of 2D Antiscatter Grids on CBCT Image Quality
This is Pilot study that investigates the CBCT(Cone beam computed tomography) image quality improvement provided by the 2D antiscatter grid technology.
- Conditions
- Prostate Cancer, Head and Neck Cancers, Upper Abdomen Cancers
- Trial name
- NCT04565457
- Testing
- Research CBCT
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Colorado, Denver
TEE Image Quality
Does Transesophageal Echocardiography Along With an Orogastric Tube Improve the Image Quality Intraoperatively?
Image quality of intraoperative transesophageal echocardiography (TEE) tends to get worse during long hours of operations. An orogastric tube (OGT) is often inserted in the beginning of the case, and left there for intermittent…
- Trial name
- NCT03454399
- Testing
- Suction orogastric tube which is attached to TEE probe
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Henry Ford Health System
Breast Cancer
Patient-Assisted Compression in 3D - Impact on Image Quality and Workflow
Patient-assisted compression (PAC) allows the patient to participate in controlling the amount of compression force during mammography and is a personalized approach that has demonstrated successful reduction in discomfort…
- Trial name
- 3D PAC (NCT03456427)
- Testing
- Patient-Assisted Compression (PAC), Technologist-Controlled (TC) Compression
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Arteriovenous Malformations, Aneurysm
Image Quality and Radiation Dose in Angiography
ClarityIQ is a novel X-ray imaging technology, that combines advanced real-time image noise reduction algorithms, with state-of-the-art hardware to reduce patient entrance dose significantly.
- Conditions
- Arteriovenous Malformations, Aneurysm, Stenosis, Dural Arteriovenous Malformations
- Trial name
- NCT01381952
- Testing
- Low dose DSA (75% reduction compared to normal dose) with novel X-ray imaging technology., Normal dose DSA with conventional X-ray technology
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska University Hospital
Breast Cancer
Patient-Assisted Compression - Impact on Image Quality and Workflow
This study is being conducted to compare the image quality of breast images obtained using standard (technologist-controlled [TC]) compression and patient-assisted (PA) compression and to evaluate the impact of PA compression on…
- Trial name
- NCT03196635
- Testing
- Patient-Assisted (PA) Breast Compression, Technologist-Controlled (TC) Breast Compression
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- GE Healthcare
Breast Cancer
Evaluating Image Quality and Comfort of an Investigational Curved Paddle Compared to a Standard Paddle
The goal of this study is to evaluate patient comfort during compression with a standard flat mammographic paddle and an investigational curved paddle.
- Trial name
- NCT03611543
- Testing
- Standard of Care Flat Paddle, Investigational Curved Paddle
- Where
- 4 sites in United States
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- Hologic, Inc.
Contrast Enhancement on Cardiac CT
Comparison of Contrast Agents During CT Angiography
The purpose of this study is to compare the effects of a certain contrast agent (iodixanol) to two other commonly used contrast agents called Iopamidol (Isovue) and iohexol (Omnipaque), on heart and kidney safety in patients…
- Trial name
- Visipaque (NCT01534975)
- Testing
- contrast agent
- Where
- United States
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Diet, Healthy
Free Living Food Waste Management and Diet Quality Improvement Using Smart Intervention and Food Image Application
The primary aim of this study is to reduce household food waste and improve individual nutrition. This will be achieved using the FoodImageTM smartphone app 1, a novel method for measuring household food acquisition, food intake…
- Trial name
- FoodImage2 (NCT05061888)
- Testing
- Smart Intervention for Food Waste Management and Replacing current diet with Fruits and Vegetables, Smart Intervention for Stress Management
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Prostate Cancer, Prostatic Neoplasm
Prostate SBRT for Locally Recurrent Prostate Cancer After Prior Radiotherapy
Background: Prostate cancer is the second leading cause of cancer death in United States (U.S.) men. Radiation is an effective treatment for most patients with localized prostate cancer, but sometimes the tumor returns.
- Trial name
- NCT03253744
- Testing
- 18F-DCFPyL, Tumor Irradiation, Prostate + tumor irradiation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Cancer Institute (NCI)
Subjects Referred to CT-examination of the Abdomen
A Randomized, Controlled Trial to Evaluate CT Image Quality Lumentin® 44
Subjects referred for abdominal or thoracoabdominal CT-examination will be randomised to either the three contrast agents Lumentin® 44, Omnipaque® or Movprep.
- Trial name
- NCT03326518
- Testing
- Lumentin® 44, Diluted Omnipaque®, Movprep®
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Lument AB
Image Quality
TEE Image Quality Improvement With Our Devised Probe Cover
With using suction tube attached TEE probe cover, we will assess its pinpoint suction capacity on image quality and surgical decision making.
- Trial name
- NCT03812185
- Testing
- Suctioning orogastric tube which is attached to TEE probe cover
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Henry Ford Health System
Coronary Artery Disease
Effects of Sublingual and Transdermal Administration of Nitroglycerin for Coronary CT Angiography on Image Quality
To evaluate image quality of coronary CT angiography (cCTA) after sublingual and transdermal administration of Nitroglycerin. Aim of this prospective research study is to investigate equivalence on image quality after sublingual…
- Trial name
- NCT02961946
- Testing
- Nitroglycerin
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Massachusetts General Hospital
Contrast Enhanced Computed Tomography (CT) Scanning
Effect of Three Side Hole Infusion Catheter on CT Image Quality Compared to a Standard Infusion Catheter
The purpose of this research study is to compare two types of catheters used for infusing the contrast dye necessary for viewing internal organs during computed tomography (CT) scanning.
- Trial name
- NCT02943226
- Testing
- Becton Dickinson Nexiva Diffusics System, Standard intravenous catheter
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- The University of Texas Health Science Center, Houston