Clinical trials: Insulin Pump Therapy
Insulin Pump Therapy in Treating Diabetic Nephropathy
Effect Insulin Pump Therapy to Patients With Diabetic Nephropathy
The recent study suggested that oxidative stress resulting from increased production of reactive oxygen species (ROS) plays a crucial role in the development of diabetic complications.
- Trial name
- NCT03174821
- Testing
- Insulin pump
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Diabetes Mellitus
Inflammatory Response to CSII Catheters in a Tummy Tuck Model
In insulin pump therapy, insulin is continuously infused into the subcutaneous adipose tissue via a continuous subcutaneous insulin infusion (CSII) catheter using a basal/bolus pattern.
- Trial name
- IRCATT (NCT03298295)
- Testing
- Continous Subcutaneous Insulin Infusion Catheter
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Diabetes Mellitus, Type 1
Postprandial Blood Glucose Control and Gastric Emptying in Type 1 Diabetes: Pathogenetic Factors and Therapeutic Options
This study evaluates the prevalence of gastric emptying (GE) in type 1 diabetic patients (DM1) free of chronic complications in comparison with a group of healthy control subjects.
- Trial name
- NCT02365740
- Testing
- gastric emptying test, gut hormones determination, Continuous Glucose Monitoring
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federico II University
Type 1 Diabetes
Prospective Study of the Impact of Insulin Pump Therapy in Young Children With Type 1 Diabetes
The purpose of the study is to examine glycemic and neuropsychological outcomes in very young children with Type I diabetes who are being started on insulin pumps and to compare their outcomes to children who are not utilizing…
- Trial name
- NCT00727220
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Indiana University
Type 1 Diabetes Mellitus
Mixed Meal Test in Type 1 Diabetes on Insulin Pump Therapy: Optimization of Artificial Pancreas
BACKGROUND. Optimal glucose control can prevent/relent tissue damage in patients with type 1 diabetes mellitus (T1DM). Ongoing efforts aim at developing closed loop control (CLC) algorithms linking subcutaneous continuous glucose…
- Trial name
- NCT02003274
- Testing
- Clamp-Mixed Meal, IVGTT-Mixed Meal Arm
- Where
- 2 sites in Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Type 2 Diabetes, Type 1 Diabetes
European, Open-label, Prospective, Multinational, Multicenter Study in Adult Subjects With Type 1 or Type 2 Diabetes Previously on MDI or CSII Therapy. Subjects Home Setting is Considered Routine Practice.
Accu-Chek® Insight Insulin Pump EU Study is a Multicenter Study to evaluate the Accu-Chek® Insight Insulin Pump in routine practice.
- Trial name
- NCT02105103
- Testing
- Accu-Chek® Insight Insulin Pump
- Where
- 8 sites in Austria, United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Type 1 Diabetes
Closed-Loop Glucagon Administration For Hypoglycemia Treatment
This study will test the hypothesis that a wearable automated bionic pancreas system that automatically delivers glucagon only can prevent or treat hypoglycemia vs. usual care for people with type 1 diabetes > 21 years old.
- Trial name
- NCT02181127
- Testing
- Glucagon-only Bionic Pancreas
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Type 1 Diabetes
Energy Balance Following Islet Transplantation
Islet transplantation may be appropriate in up to 10% of adults with Type 1 diabetes who suffer repeated episodes of hypoglycaemia with severely impaired awareness of hypoglycaemia (IAH) (1).
- Trial name
- EBFIT (NCT03063229)
- Testing
- Accelerometer, Anthropomentry, Blood tests
- Where
- United Kingdom
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Diabetes Technology, Continuous Glucose Monitoring System
Healthcare Practitioners Knowledge on Diabetes Technology
Assessment of knowledge of healthcare professionals of diabetes mellitus technology (continuous glucose monitoring systems and insulin pump therapy).
- Conditions
- Diabetes Technology, Continuous Glucose Monitoring System, Continuous Insulin Infusion System, Insulin Pump Therapy
- Trial name
- NCT07822945
- Testing
- Questionnaire assessing knowledge on diabetes technology
- Where
- Greece
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Type 1 Diabetes Mellitus
The Role of FTO Gene Polymorphism and Insulin Preparation in Obesity in Children With Type 1 Diabetes Mellitus
The project aims at assessment of the effect of the FTO gene polymorphism and the type of treatment on the development of overweight/obesity and features of metabolic syndrome in children with type 1 diabetes.
- Trial name
- FTO_T1DM (NCT01279161)
- Where
- 6 sites in Poland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Bialystok
Diabetes Mellitus, Type 1
SWITCH - Sensing With Insulin Pump Therapy to Control HbA1c
The primary objective of this study is to evaluate whether the patients with Type 1 diabetes mellitus in sub-optimal glycemic control can achieve better glycemic control by using the Medtronic MiniMed Paradigm® REAL-Time Pump…
- Trial name
- SWITCH (NCT00598663)
- Testing
- insulin pump with continuous glucose sensing (Paradigm Real-Time Insulin Pump System), insulin pump and blinded continuous glucose sensing (Paradigm Real-Time insulin pump)
- Where
- 8 sites in Austria, Denmark and 5 more
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Medtronic MiniMed, Inc.
Diabetes
Changes of the Infusion Rate in Insulin Pump Treatment
A pharmacokinetic study of insulin pump treatment using Insulin Aspart. The study consist of three different periods A, B and C where a constant the insulin infusion rate is given during the periods.
- Trial name
- NCT00449839
- Testing
- Insulin Aspart
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Type 1 Diabetes Mellitus
Managing Insulin Pumps for Exercise - Study 1
People with Type 1 Diabetes Mellitus (T1DM) like to take part in sport and exercise, but problems with metabolism and blood glucose control can make this difficult.
- Trial name
- NCT01401127
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Buckinghamshire Healthcare NHS Trust
Diabetes
Monitoring the Infusion Pressure in Insulin Infusion Sets in Healthy Adults
The purpose of this study is to compare the in-line fluid pressure (pressure of the fluid going through the tubing) and leakage (observation of fluid on and around the device) during and after subcutaneous infusion using two…
- Trial name
- NCT02382536
- Testing
- BD Scarlett Infusion set, Medtronic QuickSet Infusion Set
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Becton, Dickinson and Company
Type 2 Diabetes
Pilot Study Assessing Insulin Pump Therapy in Type 2 Diabetes
16-week, open-label, multi-center pilot study. Insulin pump naïve subjects with type 2 diabetes who are not achieving glycemic targets (screening A1C ≥ 7.0%) on an established regimen of either: 1) ≥ 2 OAs (Cohort A), 2) basal…
- Trial name
- NCT00922649
- Testing
- Insulin Pump therapy
- Where
- 6 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Animas Corporation