Clinical trials: Intraoperative Injury
Intraoperative Hypotension, Jugular Veins
Internal Jugular Vein Ultrasound and Acute Kidney Injury After Abdominal Surgery
This observational study aims to learn whether changes in the internal jugular vein during anesthesia induction can help predict low blood pressure and kidney injury after surgery. The main questions it aims to answer are: 1.
- Conditions
- Intraoperative Hypotension, Jugular Veins, Hypotension on Induction, General Anesthesia With Propofol
- Trial name
- PRO-JUGULAR (NCT07638306)
- Testing
- Internal Jugular Vein Ultrasound Assesment
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tîrgu Mureș Emergency Clinical County Hospital, Romania
Wound Complications
Effect of Intra-operative Glove-changing During Cesarean Section on Post-op Complications: A Randomized Controlled Trial
A randomized controlled trial to determine whether changing of gloves by the surgical team during cesarean section may decrease post-operative infectious morbidity and wound complications
- Trial name
- NCT02907892
- Testing
- Glove change
- Where
- United States
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Hemodynamic Instability, Opioid Use
Effects of US-guided SAPB During Breast Surgery
The serratus anterior plan (SAP) block is a technique that has recently gained popularity in the context of breast surgery. SAP block resulted in better hemodynamic stability, early ambulation and shorter hospital stay, as well…
- Conditions
- Hemodynamic Instability, Opioid Use, Block, Breast Cancer
- Trial name
- NCT04824833
- Testing
- Serratus anterior plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Ureteral Injury
Evaluation of Sodium Fluorescein Use During Intraoperative Cystoscopy After Total Laparoscopic Hysterectomy
The primary objective is to describe the safety and efficacy of intravenous sodium fluorescein to visualize ureteral efflux during intraoperative cystoscopy after total laparoscopic hysterectomy.
- Trial name
- NCT02971800
- Testing
- sodium fluorescein injection 10%
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Femoral Neck Fractures
the Effects of Perioperative Goal Directed and Conventional Fluid Management on the IVC Collapsibility Index
The investigators aimed to compare the effects of targeted fluid management and traditional fluid management on the inferior vena cava collapsibility index in participants who will undergo proximal femoral surgery.
- Trial name
- NCT05154435
- Testing
- mostcare hemodynamic monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Rotator Cuff Tears, Hemorrhage, Surgical
Effect of Intravenous Tranexamic Acid on Visual Clarity During Shoulder Arthroscopy in the Beach Chair Position
Shoulder arthroscopy offers numerous advantages and has led to a continuous increase in procedural complexity. Adequate intraoperative visual clarity is essential for successful performance of the procedure and is primarily…
- Conditions
- Rotator Cuff Tears, Hemorrhage, Surgical, Shoulder Injuries
- Trial name
- NCT05397652
- Testing
- Tranexamic Acid Injectable Product
- Where
- Croatia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Nikola Matejcic
Post-operative Infections
Reduction in IV Associated Contamination
The purpose of this study is to investigate whether implementing a novel syringe and IV stopcock cap system impregnated with alcohol will reduce IV catheter bacterial contamination and infections in patients.
- Trial name
- NCT01426217
- Testing
- Passive Bundle PSI (Problem Solving Innovations) Medical HubScrub, PSI Medical DocIt
- Where
- United States
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Burns, Hand Injuries
Range of Motion Following Intraoperative Coban Dressing Application in Hand Burns
Participants of this study will include burns requiring skin graft to hand(s). After informed consent, an occupational therapy evaluation will be performed.
- Trial name
- NCT01027520
- Testing
- application of coban dressing
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Malignant Hyperthermia
Malignant Hyperthermia Registry and Genetic Testing
The purpose of this study is to to determine the penetrance of known and probable pathogenic variants in genes and the factors that contribute to penetrance in a population of children and adults in the United States exposed to…
- Trial name
- NCT02964481
- Testing
- Whole exome sequencing
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Wound Heal
Dermabrasion in Mohs: Split-Scar Trial
The purpose of this study is to determine the potential influence of intraoperative dermabrasion on scars following Mohs Micrographic Surgery (MMS).
- Trial name
- NCT07213921
- Testing
- Dermabrasion
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Chylothorax, Esophageal Cancer
FLOTOR Pilot Study
This is a non-randomised study assessing the technique of using indocyanine green as a fluorescent dye to highlight the thoracic duct during oesophectomy.
- Conditions
- Chylothorax, Esophageal Cancer, Thoracic Duct Intra-Operative Injury
- Trial name
- FLOTOR (NCT03292757)
- Testing
- Indocyanine Green
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Intraoperative Complications, Postoperative Complications
Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.
The goal of this study is to investigate the effect of depth of neuromuscular block (NMB) on global and regional (dependent versus nondependent) respiratory mechanics during laparoscopic surgery.
- Conditions
- Intraoperative Complications, Postoperative Complications, Laparoscopy, Surgical Complications From General Anesthesia
- Trial name
- NCT02025075
- Testing
- Rocuronium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Rotator Cuff Tear
Influence of Intraoperative Repair Tension on Postoperative Healing of Full-thickness Rotator Cuff Tears
Relevant problems of rotator cuff repair: High retear rate after rotator cuff repair of 13%, despite regard of the criteria for "reparability" of a tear.
- Trial name
- TENS-RCT (NCT03318627)
- Testing
- Sterile Spring Scale
- Volunteers
- healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Wound Heal, Scar
Scar Tissue Analysis After Intraoperative Application of Stromal Vascular Fraction Cells Into Suture Line
The study will evaluate the effect of intradermal injection of stromal vascular fraction into suture line on wound healing and scarring.
- Conditions
- Wound Heal, Scar, Hypertrophic Scar, Delayed Wound Healing
- Trial name
- NCT04238468
- Testing
- Intradermal stromal vascular fraction injection
- Where
- Slovenia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Katarina Zivec
Blood Loss, Surgical, Transfusion Rate
Effect of Electrosurgery on Blood Loss and Intraoperative Transfusions in Musculoskeletal Tumor Surgery
Resection of malign musculoskeletal tumors and reconstruction with large tumor prostheses often results in relevant blood loss requiring hemodynamic stabilization and transfusion.
- Conditions
- Blood Loss, Surgical, Transfusion Rate, Electrosurgery, Tumororthopaedics
- Trial name
- NCT05164809
- Testing
- Application of novel electrodes
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Tourniquets, Knee Arthroplasty, Total
Tourniquet Pressure in Primary Total Knee Arthroplasty
This proposed novel randomized control trial (RCT) seeks to address this gap in TKA protocol by gaining a better understanding of the relationship between tourniquet pressure and time, and intraoperative performance and…
- Conditions
- Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
- Trial name
- NCT02830087
- Testing
- Tourniquet Cuff Pressure
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Scars
The Effects of Fractional Carbon Dioxide (CO2) Laser Treatment Prior to Wound Closure
The purpose of this study is to determine if fractional carbon dioxide laser treatment of a fresh wound at the time of surgery, decreases scar formation. Scar revision is commonly done at 6-10 weeks following surgery.
- Trial name
- NCT00969475
- Testing
- Lumenis fractional carbon dioxide laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Moy-Fincher Medical Group
Distal Radius Fracture
Randomized Controlled Trial Assessing the Effect of Dexamethasone on Postoperative Function After Distal Radius Fixation
The study is designed to assess the use of intraoperative dexamethasone on postoperative analgesia and stiffness after open reduction and internal fixation of distal radius fractures.
- Trial name
- NCT04889547
- Testing
- Dexamethasone, No dexamethasone
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Surgical Blood Loss, Burns
Measurement of Blood Volume Loss During Burn Surgery
Burn surgery is associated with significant reductions in hematocrit. However, it is unclear whether these reductions are the result of hemodilution from non-red cell containing intraoperative transfusions or from loss of red…
- Trial name
- NCT03340116
- Testing
- Burn surgery, Measurement of RBC volume, plasma volume, and total blood volume using Daxor BVA-100
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Brain Damage, Postoperative
Evaluation of Neuronal Damage in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy With Biomarkers
Robotic assisted laparoscopic surgery has become an alternative to open or laparoscopic technique in various surgical fields. Robot assisted laparoscopic surgery is preferred by surgeons and patients due to easy accessibility…
- Conditions
- Brain Damage, Postoperative, Surgery-Complications
- Trial name
- NCT05692804
- Testing
- Mini Mental State Examination(MMSE),Montreal Cognitive Assessment ( MoCA),S100B ( protein S100 subunit beta) ,GFAP ( glial fibrillary acidic protein ),NSE ( neuron-specific enolase )
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Akdeniz University