Clinical trials: Joint Arthrodesis
Single-level Lumbar Arthrodesis
Intravenous Lidocaine Versus Erector Spinae Plane Block After Lumbar Arthrodesis (LIBERA)
The hypothesis of this study is that intraoperative intravenous lidocaine infusion provides postoperative analgesia and opioid-sparing effects that are at least equivalent to those achieved with a bilateral erector spinae plane…
- Trial name
- LIBERA (NCT07895368)
- Testing
- Single-level posterior lumbar arthrodesis
- Where
- France
- Volunteers
- 90 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Sacroiliac Joint Pain
iFuse Implant System® Minimally Invasive Arthrodesis
The purpose of this study is to compare outcomes when patients with chronic sacroiliac joint pain undergo either SI joint fusion with the iFuse Implant System or undergo conservative management of the SI joint
- Trial name
- iMIA (NCT01741025)
- Testing
- iFuse Implant System, Conservative Management
- Where
- 9 sites in Belgium, Germany and 2 more
- Volunteers
- 103 people
- Sponsor
- SI-BONE, Inc.
Hallux Limitus, Hallux Rigidus
Surgical Treatment for Hallux Rigidus
The purpose of this study is to examine the long-term outcomes for the surgical treatment of end stage degeneration in the big toe joint.
- Trial name
- NCT01048450
- Testing
- Joint Resection- Keller Procedure, Joint Fusion, Hemi-metallic Joint Implant
- Where
- 6 sites in United States
- Volunteers
- 158 people
- Sponsor
- American College of Foot and Ankle Surgeons
Sacroiliitis, Sacroiliac; Fusion
Evaluation of the iFuse Bedrock Technique in Association With Posterior Lumbosacral Fusion With Iliac Fixation.
The purpose of this study is to describe the impact of the iFuse Bedrock technique to decrease post-operative pains in patients who underwent multilevel posterior lumbosacral fusion.
- Conditions
- Sacroiliitis, Sacroiliac; Fusion, Lumbosacral; Fusion, Spine Deformity
- Trial name
- NCT05276024
- Testing
- iFuse Bedrock technique
- Where
- 2 sites in France
- Volunteers
- 48 people
- Sponsor
- Polyclinique Bordeaux Nord Aquitaine
Ankle Deformity, Ankle Arthritis
ViviGen Cellular Bone Matrix for Hindfoot or Ankle Arthrodesis
To evaluate the fusion status of the hindfoot bones after receiving the ViviGen graft, an FDA approved cellular bone matrix. This is used in a population indicated for hindfoot arthrodesis as an alternative to an autograft.
- Trial name
- ViviGen (NCT04138017)
- Testing
- ViviGen
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Virginia
Ankle Injuries
3D Printed Guide in Ankle Arthrodesis
This study applies 3D-printed customized guide plate in assisting the accurate drilling of Kirschner wire in ankle arthrodesis. This technique can shorten the operation time, reduce the intra-operative radiation, and do not…
- Trial name
- NCT03626935
- Testing
- 3D-printed customized guide plate
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Southwest Hospital, China
Osteoarthritis
Arthroscopic Ankle Arthrodesis: Measuring Post-operative Pain to Assess the Potential for Outpatient Surgery.
Post-operative pain will be measured using a pain diary for one week post-surgery. The purpose is to test the assumption that the arthroscopic technique leads to less post-operative pain and results in shorter hospital stays when…
- Trial name
- NCT01370252
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Hammond, Allan, M.D.
Cervical Arthrodesis
rhBMP-2 in Cervical Arthrodesis
This prospective study will investigate the use of recombinant human bone morphogenetic protein (rhBMP-2) in the current surgical standard of care for cervical spine pathology.
- Trial name
- NCT02178605
- Testing
- Cervical arthrodesis with rhBMP-2
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Virginia Spine Institute
Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis
Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages
The purpose of this randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo combined interbody/posterolateral lumbar fusion procedures, supplemented with pedicle…
- Conditions
- Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Lumbar Spinal Deformity
- Trial name
- NCT03647501
- Testing
- Interbody cage (titanium), Interbody cage (PEEK)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Ohio State University
Wrist Arthritis, Wrist Osteoarthritis
Study of Wrist Fusions With the Medartis Aptus Arthrodesis Plate
The primary working hypothesis of this study is whether wrist arthrodesis leads to an improvement in functional status in both rheumatoid arthritis and post-traumatic osteoarthritis.
- Trial name
- STIF (NCT05875896)
- Testing
- Total wrist fusion
- Where
- Germany
- Volunteers
- 73 people
- Sponsor
- Waldfriede Hospital
Sacroiliac Joint Disruption, Degenerative Sacroiliitis
Post-Market Feasibility Study of the Tenon Medical CATAMARAN™ SI Joint Fusion System
The purpose of this study is to evaluate the outcomes of patients with sacroiliac joint pain treated with the CATAMARAN SI Joint Fusion System.
- Trial name
- NCT05633888
- Testing
- CATAMARAN SI Joint Fusion System
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tenon Medical
Orthopedic Equine Varus Deformity
Talonavicular Arthrodesis and Surgical Treatment of Ankle and Varus Foot
This study should refine our surgical indications and to establish a decision tree of medical and surgical treatment of this common and troublesome strain functionally which is equino-varus.
- Trial name
- talobot (NCT02790346)
- Testing
- arthrodesis talonavicular, tendon gestures
- Where
- France
- Volunteers
- 33 people
- Sponsor
- University Hospital, Montpellier
Ankle and Hindfoot Arthrodesis
Long-term Safety and Effectiveness of AUGMENT® Injectable Bone Graft Compared to Autologous Bone Graft
The objective of this long-term study is to evaluate the long-term effectiveness and safety of AUGMENT® Injectable Bone Graft vs. autologous bone graft.
- Trial name
- NCT03998137
- Testing
- AUGMENT® Injectable Bone Graft, Standard of Care
- Volunteers
- 94 people
- Sponsor
- BioMimetic Therapeutics
Knee Osteoarthritis
Comparison of Proprioception for HTO (High Tibial Osteotomy) and UKA (Unicompartmantal Knee Arthroplasty)
Osteoarthritis of the knee (KOA), a common degenerative joint disease, affects a significant part of the world's population. Although it can hold all the compartments in the knee joint, isolated medial compartment involvement has…
- Trial name
- NCT05993637
- Testing
- Examination of propriception
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Pilon Fracture, Arthritis
Anterior Tibiotalar Arthrodesis With Blade Plate Fixation
The aim of this study is to evaluate the clinical and radiographic outcomes of patients who have previously undergone tibiotalar arthrodesis using an anterior approach with blade-plate fixation for tibiotalar arthritis secondary…
- Trial name
- NCT01818466
- Sponsor
- University of Utah
Ketorolac, Joint Fusion
Effect of Postoperative Ketorolac on Bone Healing After Joint Fusion
In the midst of the opioid crisis, the use of non-narcotic pain medication has garnered increased interest, particularly in the field of orthopaedic surgery, where narcotic medications are routinely prescribed postoperatively.
- Trial name
- NCT04872283
- Testing
- great toe (1st metatarsophalangeal joint) fusion, IV Ketorolac, Ketorolac Pill
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Spinal Fusion, Lumbar Fusion
Lumbar Fusion With Porous Versus Non-Porous Cages
The objective of this single site, randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo lumbar interbody fusion procedures (TLIF), supplemented with pedicle screw…
- Conditions
- Spinal Fusion, Lumbar Fusion, Arthrodesis, Spondylolisthesis
- Trial name
- NCT05583864
- Testing
- CONDUIT Porous Titanium Spinal Cage, PROTI 360 Titanium-Coated PEEK Spinal Cage
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Francis Farhadi
Hammer Toe, Claw Toe
Short Term Follow-up of Patient Implanted With the Proximal Interphalangeal Implant
Hammertoe and ClawToe are ones of the most common foot deformities. The second toe is the most frequently affected, but the other small toes may also be involved. When nonoperative treatment fails, surgery often is recommended.
- Conditions
- Hammer Toe, Claw Toe, Shortening 2nd Toe, Revision of Arthrodesis or Arthroplasty Failure
- Trial name
- NCT01285011
- Where
- 5 sites in Belgium, France and 1 more
- Volunteers
- 156 people
- Sponsor
- Integra LifeSciences Services
Intervertebral Disc Degeneration
Adjacent Segment Mechanics in Cervical Arthrodesis Patients
This study aims to determine to what extent patient-specific factors, iatrogenic factors, and biomechanical factors influence cervical spine mechanics after single-level and two-level arthrodesis.
- Trial name
- NCT03028402
- Testing
- C5-C6 arthrodesis
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Scoliosis
The Idiopathic Scoliosis and Its Treatment (Orthopaedic and Surgery): Effect of the Severity, the Orthosis and the Arthrodesis on the Gait
The purposes of this study were as follows: 1) to compare locomotion parameters (kinematic, EMG, mechanical work and energy cost changes during walking in able-bodied subjects and AIS patients,2) to evaluate the effects of the…
- Trial name
- scoliosis (NCT00842218)
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain