Clinical trials: Language
Brain Injury, Vascular, Aphasia
Treatment of Grammatical Time Marking in Post-Stroke Aphasia
The study aims to assess an individual or self-administered computer therapy's effectiveness in grammatical time marking. The main objective is to examine whether the therapy improves grammatical time marking of inflected verbs…
- Conditions
- Brain Injury, Vascular, Aphasia, Stroke
- Trial name
- NCT05656638
- Testing
- Speech and language therapy
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- University of Neuchatel
Dyslexia, Adolescent
Usefulness of an Assistive Technology Training Program for Adolscents With Dyslexia
Specific Written Language Disorders (SWLD) are severe and lasting impairments in the development of written language that affect approximately 10% of the school-age population.Concerned patients don't have any intellectual…
- Trial name
- FormONC (NCT05636813)
- Testing
- Training
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Caen
Glioma
Awake Intraoperative Language Mapping and Chinese Probabilistic Map Construction
The study aims at constructing a Chinese language probabilistic map by awake intraoperative direct electrical stimulation (DES) language mapping.
- Trial name
- NCT03641391
- Testing
- Intraoperative direct cortical electrical stimulation, Intraoperative direct subcortical electrical stimulation
- Where
- 3 sites in China
- Volunteers
- 300 people
- Sponsor
- Huashan Hospital
Chronic Low-back Pain, Neck Pain
Turkish Version of Revised Neurophysiology of Pain Questionnaire
The Neurophysiology of Pain Questionnaire was first developed in English to test whether healthcare staff and patients could exactly understand pain neurophysiology.
- Trial name
- NCT04099160
- Testing
- Evaluation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 182 people
- Sponsor
- Akdeniz University
Aphasia, Malignant Brain Tumor
Listen Aphasia Pilot Study
This is a feasibility and pilot study to refine and test LISTEN, an AI-based augmentative and alternative communication (AAC) smartphone app, integrated into the patient's personal electronic device, to augment and facilitate…
- Trial name
- LISTEN (NCT07732140)
- Testing
- LISTEN (AI-based AAC smartphone app)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Dana-Farber Cancer Institute
Aphasia, Broca
Effects of MTS-r on Speech Production in Non-fluent Aphasia Post-ischemic Stroke Patients
Aphasia is one of the most disabling complications in language production in patients with left hemisphere stroke. About 19% of patients who experience aphasia may have a spontaneously recovery after several weeks or months.
- Trial name
- Aphasia-ACV (NCT02241213)
- Testing
- Transcranial Magnetic Stimulation (TMS-r)
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Fundación Cardiovascular de Colombia
Aphasia
Modulating Intensity and Dosage of Aphasia Scripts
The purpose of this study is to evaluate how changing conditions of speech-language treatment (namely, amount of repetition and distribution of practice schedule) affects the language outcome of participants with aphasia…
- Trial name
- MIDAS (NCT04138940)
- Testing
- Script Training
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Shirley Ryan AbilityLab
Primary Progressive Nonfluent Aphasia
Transcranial Magnetic Stimulation in Nonfluent/Agrammatic Variant Primary Progressive Aphasia
Nonfluent/agrammatic variant primary progressive aphasia (nf/avPPA) is a fatal neurodegenerative disease that begins with isolated language deficits. There is currently no cure or treatment for this disease.
- Trial name
- NCT03153540
- Testing
- Active iTBS
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of British Columbia
Oculopharyngeal Muscular Dystrophy
Screening in Oculopharyngeal Muscular Dystrophy
Oculopharyngeal muscular dystrophy (OPMD) is a rare myopathic disease that results in progressive degeneration of the oral and pharyngeal muscular, resulting in severe dysphagia and dysarthria.
- Trial name
- NCT02877784
- Testing
- Videofluoroscopic swallowing study, Functional Oral Intake Scale, Eating Assessment Tool-10
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
Aphasia
Learning to Communicate Successfully Approach for Urdu Speaking Patients With Chronic Aphasia
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA), a culturally sensitive communication intervention manual for Urdu-speaking adults with chronic aphasia.
- Trial name
- LCSA (NCT07889778)
- Testing
- Learning to Communicate Successfully Approach (LCSA)
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Language, Executive Dysfunction
Effect of Stimulation of Dorsolateral Prefrontal Cortex on Language Control
This study aims to evaluate the effect of stimulation of prefrontal regions on language performance (e.g. word translation and picture naming).
- Trial name
- NCT02289521
- Testing
- Transcranial Direct Current Stimulation
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Aphasia, Acquired, Stroke, Acute
Neolexon® Aphasia-App in Acute Aphasia After Stroke
Up to now there is proven evidence of traditional logopedic therapy in aphasia, but recent computer-based algorithms also showed their evidence so far.
- Trial name
- Lexi (NCT04080817)
- Testing
- Neolexon, Speech therapy, Self training
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Presbyopia, Low Vision
Development and Validation of a Digital Optotype for Near Vision in Greek Language.
Primary objective of our study is to develop and validate a computer-based digital near-vision optotype based on the Greek version of the print MNREAD.
- Conditions
- Presbyopia, Low Vision, Near Vision
- Trial name
- DeDART (NCT04242836)
- Testing
- MNREAD testing
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Aphasia
TMS in Aphasia Recovery
Stroke often causes substantial problems in speaking or understanding speech. Treatments for these problems are currently very limited.
- Trial name
- NCT04777214
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pennsylvania
Inactivity
Pasos Hacia La Salud - Physical Activity Intervention for Latinas
In this study, investigators are specifically targeting Latina women as they are more likely to be inactive and, therefore, are at higher risk for developing chronic conditions such as obesity, diabetes, or cardiovascular…
- Trial name
- NCT01834287
- Testing
- Physical Activity Intervention, Wellness Control
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Genetic Syndrome, Language Development
Study of an Early Parenting Intervention for Children With Genetic Abnormalities and Mental Health Problems
The GAP study is a randomized controlled trial that aims to determine the feasibility and efficacy of the "Incredible Years Autism Spectrum and Language Delays" (IY-ASLD®) intervention for families of children with developmental…
- Conditions
- Genetic Syndrome, Language Development, Autism or Autistic Traits, Parenting
- Trial name
- The GAP (NCT06125093)
- Testing
- Incredible Years Autism Spectrum and Language Delays Parent Program (IY-ASLD®)
- Where
- 3 sites in Spain
- Volunteers
- 53 people
- Sponsor
- Fundació Sant Joan de Déu
Brain (Nervous System) Cancers, Brain Arterial Disease
A Vision-Language Foundation Model for Brain Disease Diagnosis From Multimodal Data
The goal of this observational study is to develop an innovative, comprehensive, and explainable AI vision-language foundation model (VLM) to advance the diagnosis and interpretation of brain diseases using multi-modal data.
- Conditions
- Brain (Nervous System) Cancers, Brain Arterial Disease, Neuro-Degenerative Disease, Brain Tumors
- Trial name
- NCT07126821
- Testing
- No Interventions
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Stuttering, Fluency Disorders
Enhancing Speech Fluency With Non-invasive Brain Stimulation in Developmental Stuttering
This study aims to test whether the addition of transcranial direct current stimulation (TDCS) to speech fluency training results in improvements in speech fluency in adults with developmental stuttering.
- Conditions
- Stuttering, Fluency Disorders, Speech Disorders
- Trial name
- NCT02288598
- Testing
- Anodal TDCS, Fluency Training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Oxford
Preoperative Care
ChatGPT v.s. Human in Writing a Preoperative Visit Sheet
The goal of this study is to evaluate the performance of large language models i.e. ChatGPT, in making preoperative visit sheets using clinical records.
- Trial name
- NCT05945004
- Testing
- ChatGPT-4, Clinician
- Volunteers
- 120 people
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Aphasia
Speeded Anomia Treatment in Chronic Post-stroke Aphasia
The main aim of the study is to investigate the effect of a novel, speeded anomia therapy (Conroy et al., 2018) in a large population of patients with chronic post-stroke aphasia.
- Trial name
- NCT05512884
- Testing
- Speeded anomia therapy
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Cambridge