Clinical trials: Laser Therapy
Peri-Implantitis
Peri-implantitis Treatment: Clinical Results of Conventional Treatment vs. the Addition of Biolase
The purpose of the study is to observe the effects of two commonly utilized treatment modalities to treat peri-implantitis and to compare the results.
- Trial name
- NCT03544515
- Testing
- Er,Cr:YSGG laser, Scaling, Inactive Er,Cr:YSGG
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Columbia University
Solar Lentigines
Side Effects of Q-Switched Ruby Laser for the Treatment of Lentigines in Light and Dark Skin Types
The purpose of this study is a comparison of efficacy and side effects of Q-switched Ruby laser treatment for solar lentigines in two different skin types II and IV.
- Trial name
- NCT00386204
- Testing
- Q-switched Ruby Laser
- Where
- Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Skin Thickness, Skin Stiffness
Effects of Vibration Therapy on Plantar Skin Properties
The goal of this clinical trial is to learn if there are changes in plantar skin surface in the first metatarsal head (M1) after getting local vibration treatments.
- Conditions
- Skin Thickness, Skin Stiffness, Microcirculation
- Trial name
- NCT07863843
- Testing
- Local vibration
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asia University
Implant, Peri-Implantitis
Efficacy of Diode Laser in Peri-implantitis
The aim of this study was to compare the efficacy of a diode laser (DL) as an adjunct to conventional scaling in the treatment of mild-to-moderate peri-implantitis.
- Conditions
- Implant, Peri-Implantitis, Alveolar Bone Loss, Complications
- Trial name
- NCT02362854
- Testing
- Conventional peri-implantitis treatment, DL application in peri-implantitis
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Open Angle Glaucoma, Ocular Hypertension
PSLT Compared to Prostaglandin Analogue Eye Drops
This study aims to compare the efficacy of PSLT and the topical use of prostaglandin-like hypotensive eye drops in the treatment of ocular hypertensive or glaucomatous patients in decreasing intraocular pressure and measuring…
- Trial name
- NCT05241938
- Testing
- PSLT, Prostaglandin analogue eye drops
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Periodontitis, Periodontitis Stage III
Diode Laser-Assisted Periodontal Therapy Enhances Clinical Outcomes for Deep Periodontal Pockets in Smokers
This study investigated the adjunctive effects of diode laser therapy in smokers with severe periodontitis. Thirty-three patients were randomized to non-surgical periodontal therapy (SRP) with or without diode laser.
- Conditions
- Periodontitis, Periodontitis Stage III, Periodontal Disease, Diode Laser Therapy
- Trial name
- NCT07213752
- Testing
- Diode Laser Application in Deep Periodontal Pockets, Professional Mechanical Plaque Removal, Scaling and Root Planing
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Wound Heal
Effect of Combined Red and Near Infrared Light-emitting Diode (LED) Therapy on Tissue Regeneration Post Laser Treatment
The purpose of this study is to evaluate the effect of light therapy on wound healing after laser treatment.
- Trial name
- NCT04834817
- Testing
- Celluma POD
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Vulvovaginal Atrophy
Clinical Investigation to Assess the Safety and Efficacy of the Laser for the Treatment of Vulvovaginal Atrophy
The purpose of this study is to assess the safety and the efficacy of a laser in the treatment of vulvovaginal atrophy (VVA), that is to assess the change in the severity of the vaginal dryness symptom, by means of a visual…
- Trial name
- NCT02085980
- Testing
- Laser treatment
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- El. En. SpA
Cicatrix
Pulsed-dye Laser Treatment Prior to Surgical Excision
This prospective pilot study will investigate whether use of a pulsed dye laser (PDL) prior to surgical excision can improve the appearance and symptoms of scars.
- Trial name
- NCT02458976
- Testing
- PDL
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Postmenopausal Period, Vaginal Atrophy
Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser
The aim of study is characteristic of changes in the vaginal wall after treatment of neodymium laser radiation with a wavelength of 1064 nm.
- Conditions
- Postmenopausal Period, Vaginal Atrophy, Vaginal Prolapse
- Trial name
- NCT05335317
- Testing
- Laser Treatment, Topical hormone estriol, Сlinical blood analysis
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MeLSyTech, Ltd
Periodontitis, Periodontitis, Adult
Clinical and Microbiological Evaluation of Laser Therapy in the Treatment of Periodontal Disease in Stages III and IV
The aim of this clinical trial is to evaluate photodynamic therapy and photobiomodulation in the periodontitis treatment. To evaluate the clinical and microbiological response of conventional periodontal treatment associated with…
- Trial name
- NCT06426550
- Testing
- Antimicrobial photodynamic therapy and 0.005% methylene blue (PDT), Photobiomodulation with a red laser (PBM-RL), Saline solution
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Erythematotelangiectatic Rosacea
Pulsed Dye Laser Treatment and Oxymetazoline Hydrochloride (HCL) 1% Cream for Erythematotelangiectatic Rosacea
This study will compare treatment outcome with pulsed dye laser, when used used as an adjunctive treatment to oxymetazoline HCl 1% cream, compared to oxymetazoline HCL 1% cream alone, for patients with moderate or severe…
- Trial name
- NCT04153188
- Testing
- The Vbeam® Prima System, Oxymetazoline HCL 1% Cream
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Periodontitis
Low Laser Therapy and Hyaluronic Acid as an Adjunct to Non-surgical Periodontal Therapy
Periodontal disease is an oral disease characterized by microbially associated, host-mediated inflammation of the periodontium. In the treatment of periodontal disease, conventional periodontal therapy includes both surgical and…
- Trial name
- NCT05907161
- Testing
- SRP+LASER (Dentsply Sirona - SIROLaser Blue), SRP+HA, SRP
- Where
- Slovenia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Lentigines, Post Inflammatory Hyperpigmentation
Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser
To investigate the benefit of the application of topical high potency steroid on the incidence of post inflammatory hyperpigmentation after laser treatment.
- Trial name
- NCT02492373
- Testing
- topical 0.05% Clobetasol propionate ointment, Q switched Nd:YAG laser 532 nm
- Where
- Thailand
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Muscle Tightness
Laser Therapy on Hamstring Muscle Among Young Adults
A total of 154 healthy young individuals will be recruited by purposive sampling method to participate in a randomized, single-blinded, sham-controlled study.
- Trial name
- NCT05077761
- Testing
- Active High-intensity laser therapy
- Where
- India
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Malocclusion
OrthoPulse 2.0 and 2.1 Feasibility Evaluation
OrthoPulse is a device that uses near-infrared light therapy in order to decrease orthodontic treatment time. The aim of this study is to evaluate OrthoPulse products modified with extended arrays, OrthoPulse 2.0 and OrthoPulse…
- Trial name
- BX13 (NCT03683017)
- Testing
- OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear
- Where
- 7 sites in United States, Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Vagus Nerve Stimulation
Multi-device Testing for Autonomic Nervous System Stimulation
The Vagus nerve (VN) serve as an "unconscious inner brain" that integrates messages from the body and provides metabolic homeostatic regulation to various organs.In this study the investigators want to compare different ways to…
- Trial name
- NCT04341649
- Testing
- Manual Head Massage, BREO Helmet Massager, Low Laser Therapy (LLT)
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Skin Stiffness, Skin Thickness
Evaluation Skin Stiffness Gradient on Skin After LLLT
This study evaluates the effects of Low-Level Laser Therapy (LLLT) on skin elasticity by measuring a 3x3 stiffness gradient across 9 points spaced 1 cm apart.
- Conditions
- Skin Stiffness, Skin Thickness, DFU, Wound and Injuries
- Trial name
- NCT07680309
- Testing
- LLLT intervention on skin biomechanical properties in different duration and wavelength, LLLT intervention on skin biomechanical properties in different duty cycle and applied frequency
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asia University
Low Level Laser Therapy, Photobiomodulation
Influence of PBM on Anaerobic Capacity Under Normoxia and Hypoxia
The photobiomodulation (PBM) shows positive results in muscle performance, fatigue reduction, management of blood lactate production, analgesia and in the increase of VO2 maximal, favoring the increase of ATP production and thus…
- Conditions
- Low Level Laser Therapy, Photobiomodulation, Performance, Sport
- Trial name
- NCT05595564
- Testing
- Photobiomodulation therapy
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Knee Arthritis Osteoarthritis
Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities
This study aims to compare the effectiveness and safety of High-Intensity Laser Therapy (HILT) with conventional physical therapy treatments in patients with knee osteoarthritis.
- Trial name
- HILT-CM (KOA) (NCT07551245)
- Testing
- High-Intensity Laser Therapy (HILT), Conventional Physical Therapy Modalities
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Erbil Polytechnic University