Clinical trials: Liver Percutaneous Biopsy
Liver Cirrhosis
EUS-guided Versus Percutaneous Ultrasound-guided Biopsy for Parenchymal Liver Disease
Liver biopsy may be indicated in various clinical scenarios to help diagnose and manage liver diseases. Endoscopic ultrasound (EUS) liver biopsy and percutaneous USG guided liver biopsy are two methods used to obtain liver tissue…
- Trial name
- NCT06047327
- Testing
- EUS guided liver biopsy, Percutaneous Liver Biopsy
- Where
- India
- Volunteers
- 90 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Liver Diseases, Liver Fibrosis
Prospective Single Centre Observational Study to Compare the Diagnostic Yield of Different Modalities of Liver Biopsy
The goal of this study is to learn about endoscopic ultrasound(EUS) guided liver biopsy and how this compares to traditional methods of obtaining liver biopsy samples, in patients with liver disease.
- Trial name
- NCT05912179
- Testing
- Liver biopsy - percutaneous, Liver biopsy - transjugular, liver biopsy - EUS guided
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Brain Death, Liver Disease
Pre-recovery Bedside Liver Biopsy in Brain Death Organ Donors
This study's objective is to obtain preliminary data to test the hypotheses that percutaneous liver biopsy in brain death donors is safe and provides reliable histological information.
- Trial name
- PPB (NCT01810640)
- Testing
- Percutaneous Liver Biopsy
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Rutgers, The State University of New Jersey
Bleeding Disorder, Spleen Lesion
Operator and Patient Acceptance of Radiofrequency Cautery of the Biopsy Track During Percutaneous Liver, Kidney or Spleen Biopsy Procedures.
The goal of this study is to assess the physician and patient experience of radio frequency (RF) track cautery in patients undergoing needle biopsy of the liver, kidney, or spleen who have one or more risk factors for…
- Conditions
- Bleeding Disorder, Spleen Lesion, Liver Diseases, Kidney Diseases
- Trial name
- NCT05790109
- Testing
- RF track cautery during percutaneous organ biopsy
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Hepatocellular Carcinoma
A Pilot Study of Optical Molecular Imaging for Percutaneous Biopsy of Hepatocellular Carcinoma Using Indocyanine Green
This research study is evaluating an imaging contrast agent called indocyanine green, also known as ICG, in combination with image guided liver biopsies.
- Trial name
- NCT01962649
- Testing
- ICG, Optical molecular imaging
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Fibrosis
Comparison of EUS-Guided Liver Biopsy With Percutaneous Liver Biopsy
There are several ways to perform liver biopsies, including the percutaneous route (historical gold standard) and via endoscopic ultrasound (EUS) guidance.
- Trial name
- NCT02947516
- Testing
- Endoscopic ultrasound-guided liver biopsy, Percutaneous liver biopsy
- Sponsor
- Brigham and Women's Hospital
Chronic Liver Disease
Comparison and Outcomes of Endoscopic Ultrasound Liver Biopsies Versus Percutaneous Liver Biopsies
Histopathological examination of liver tissue is used to determine the etiology and extent of liver disease. In order for a clinician to make a better-informed decision regarding a patient with liver disease, the liver biopsy…
- Trial name
- NCT04751045
- Testing
- EUS liver biopsy
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Missouri-Columbia
Liver Disease
Comparing Pain in Patients Undergoing Percutaneous Versus Transjugular Techniques of Liver Biopsy
Background: In a liver biopsy, a small piece of liver is removed. A percutaneous liver biopsy (PLB) is done through a needle on the right side of your belly.
- Trial name
- NCT02311348
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Oncology, Interventional Radiology
Clinical Evaluation of an Augmented Reality Intraprocedural Needle Guidance Platform for Soft Tissue Biopsy
This clinical feasibility evaluation is intended to further characterize and quantify the potential benefits of the FDA-cleared XR90 Augmented Reality (AR )imaging and guidance platform utilization in percutaneous soft tissue…
- Conditions
- Oncology, Interventional Radiology, Liver Carcinoma, Renal Carcinoma
- Trial name
- NCT07046832
- Testing
- Augmented Reality Guided Biopsy, Ultrasound Guided Biopsy
- Where
- 3 sites in United States
- Volunteers
- 104 people
- Sponsor
- MediView XR, Inc.
Pulmonary Coin Lesion, Colon Cancer Liver Metastasis
Optical Detection of Malignancy During Percutaneous Interventions
Investigation of application possibilities of optical spectroscopy within the field of oncology. Optical spectroscopy enables the possibility to specifically differentiate between different (human) tissues.
- Conditions
- Pulmonary Coin Lesion, Colon Cancer Liver Metastasis, Breast Cancer
- Trial name
- NCT01730365
- Testing
- Core biopsy procedure
- Where
- Netherlands
- Volunteers
- 104 people
- Sponsor
- Philips Healthcare
Percutaneous Liver Biopsy
Percutaneos Liver Biopsy in Pediatric Patient : Diagnostic Significance and Pattern of Liver Diseases
In this study, we aim to evaluate the spectrum and pattern of liver diseases diagnosed by percutaneous tru-cut needle liver biopsy.
- Trial name
- NCT06773390
- Testing
- Percutaneous liver biposy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Liver Biopsy
Endoscopic Ultrasound vs Percutaneous Route for Liver Biopsy
This study is to evaluate and directly compare the technical success, tissue quality, diagnostic efficacy and safety profile of Percutaneous and Endoscopic Ultrasound-guided Liver Biopsy.
- Trial name
- NCT04003766
- Testing
- biopsy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AdventHealth
Liver Cirrhosis, Liver Disease Chronic
Assessing EUS and Percutaneous Untargeted Liver Biopsy Quality
This prospective, single-center study evaluates and compares the tissue sample quality and patient comfort of different liver biopsy methods.
- Conditions
- Liver Cirrhosis, Liver Disease Chronic, Liver Transplant
- Trial name
- EUS-PERC (NCT07701031)
- Testing
- EUS Liver biopsy 19G FNA, EUS LB 19G FNB, EUS LB 22G FNB
- Where
- Germany
- Volunteers
- 146 people
- Sponsor
- University Hospital Muenster
Chronic Liver Disease (CLD), Liver Transplantation
Patient Reported Outcomes In Liver Biopsy (EUS vs. Percutaneous)
Patient Experience in Endohepatology Liver biopsy is a crucial procedure for the diagnosis and/or staging of liver diseases. Common indications for non-targeted biopsies include unexplained elevated liver function tests (LFTs)…
- Conditions
- Chronic Liver Disease (CLD), Liver Transplantation, Cirrhosis
- Trial name
- PRO-LIVER (NCT07506642)
- Testing
- EUS Liver Biopsy, Percutaneous Liver Biopsy
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- University Hospital Muenster
Liver Mass, Liver Fibroses
Pre-procedure Planning for Liver Biopsy or Radiofrequency Ablation Using CT or MR/US Fusing Imaging
The purpose of this study is to determine whether fusion technique of preradiofrequency ablation (RFA) or percutaneous liver biopsy cross-sectional imaging (CT or MR) and real-time ultrasonography would improve feasibility of RFA…
- Trial name
- NCT02967198
- Testing
- CT/US fusion, ultrasound shear wave elastography
- Where
- South Korea
- Volunteers
- 185 people
- Sponsor
- Seoul National University Hospital
Chronic Hepatitis C, Chronic Hepatitis B
Safety Profiles of Liver Biopsy in Hemodialysis Patients With Chronic Viral Hepatitis Pre-treated With Vasopressin
Percutaneous liver biopsy (PLB) is the gold standard for grading necroinflammation and staging fibrosis in patients with chronic viral hepatitis.
- Conditions
- Chronic Hepatitis C, Chronic Hepatitis B, Biopsy, Hemodialysis
- Trial name
- NCT00635310
- Testing
- Percutaneous liver biopsy
- Where
- 5 sites in Taiwan
- Volunteers
- 3,520 people
- Sponsor
- National Taiwan University Hospital
Image-guided Biopsy, Liver Biopsy
Efficacy and Safety of Percutaneous Liver Biopsy With Needle Tract Plugging on Outpatient Basis
A prospective, randomized, two-arm, single-center study to compare efficacy and safety of percutaneous ultrasound-guided liver biopsy of conventional method (multiple liver punctures) versus coaxial method followed by needle…
- Trial name
- COGEL (NCT05614973)
- Testing
- Conventional method, Coaxial method with needle-track plugging
- Where
- South Korea
- Volunteers
- 122 people
- Sponsor
- Yonsei University
Lung Percutaneous Biopsy, Liver Percutaneous Biopsy
Needle-based Confocal Laser Endomicroscopy in Fluoroscopy-guided Procedures
This study is a prospective study in order to demonstrate the technical feasibility and safety of doing endomicroscopic imaging during interventional radiology procedure in two main indications: lung and liver.
- Trial name
- NCT02224885
- Testing
- CT-guided percutaneous biopsy or ablation
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Mauna Kea Technologies
Liver Percutaneous Biopsy or Ablation, Kidney Percutaneous Biopsy or Ablation
Needle-based Confocal Laser Endomicroscopy in CT-guided Percutaneous Procedures
This study is a prospective study in order to demonstrate the technical feasibility and safety of doing endomicroscopic imaging during interventional radiology procedure in two main indications: Kidneys and liver.
- Trial name
- NCT02288104
- Testing
- needle based confocal endomicroscopy
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Mauna Kea Technologies
Liver Neoplasms
A Trial on Contrast-enhanced Ultrasound Versus Conventional Ultrasound Guided Biopsy of Liver Neoplasms
The purpose of this study is to estimate the clinical value of contrast-enhanced ultrasound in percutaneous biopsy for liver occupied lesion.
- Trial name
- NCT02413437
- Testing
- CEUS guided biopsy, US guided biopsy, Ultrasound
- Where
- China
- Volunteers
- 2,088 people
- Sponsor
- Peking University Cancer Hospital & Institute