Clinical trials: Lower Extremity Function
Hip Fractures (ICD-10 72.01-72.2)
Risk Early Warning Management for Postoperative Hip Fracture Rehabilitation and Delirium Prevention in Elderly Patients
This clinical study aims to evaluate the effectiveness of a perioperative risk early warning management strategy in patients undergoing surgical treatment for hip fractures.
- Trial name
- NCT06966947
- Testing
- Risk Early Warning Management, Standard Perioperative Care
- Where
- China
- Volunteers
- 284 people
- Sponsor
- People's Hospital Affiliated to Hubei University of Medicine
Neuromuscular Disorders
Bidirectional Tuning of the AFO Stiffness
The goal of this pilot study with a pre-post design is to investigate the effects of separate individualization of the AFO stiffness towards plantar- and dorsiflexion in a spring-hinged AFO on walking compared to a spring-like…
- Trial name
- NEUROSWING (NCT06412055)
- Testing
- NEURO SWING AFO (Fior& Gentz, Lüneburg, Germany), WalkOn Reaction® (Ottobock, Duderstadt), Matrix Max2® (TruLife, Dublin, Ireland)
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Amputation, Diabetes
Thermoregulation in Individuals With a Leg Amputation
The goal of this project is to understand the factors that affect skin temperature (e.g., tissue above amputation site, and opposite foot) in people with amputation and diabetes.
- Trial name
- NCT06458426
- Testing
- shock-absorbing prosthesis
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Utah
ACL Injuries
Plyometric Training With or Without Hamstring Strengthening for Preventing ACL Injuries in Female Amateur Athletes
This randomized controlled trial explored the effect of plyometric training with or without hamstring strengthening in preventing anterior cruciate ligament (ACL) injuries among female amateur athletes aged 18 to 30.
- Trial name
- NCT07047833
- Testing
- Plyometric Training with Hamstring Strengthening, Plyometric Training Only
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Stroke
Comparative Effects of PNF and mCIMT on Lower Limb Function in Patient With Stroke
Stroke, which is frequently characterized by weakness, poor balance, and decreased mobility that impede independence in everyday activities, has been identified as a major cause of long-term impairment globally.
- Trial name
- NCT07331714
- Testing
- PNF, mCIMT
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Ankle Injuries
Operative Versus Non Operative Treatment for Unstable Ankle Fractures
The purpose of the study is to compare functional outcomes and recovery following surgical and non surgical treatment of potentially unstable , isolated fibula fractures.
- Trial name
- NCT00336752
- Testing
- non operative treatment, operative treatment of ankle fractures
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lumbar Radiculopathy
Mulligan BLR Versus Mulligan TSLR Versus Neural Mobilization n Patient With Lumber Radiculopathy
The goal of this study is to compare the effectiveness of mulligan traction Straight Leg Raise and mulligan's bent leg rise and neural mobilization to conventional therapies in order to assess which treatment is more successful…
- Trial name
- NCT05258214
- Testing
- Mulligan Bent Leg Raise, Mulligan Traction Straight Leg Raise, Neural Mobilization
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Athletic Performance, Functional Movement
Functional Movement, Balance, and Strength in Professional and Amateur Soccer Players
This observational comparative study aims to evaluate differences in functional movement quality, dynamic balance, lower extremity muscle strength, and jumping performance between professional and amateur male soccer players.
- Conditions
- Athletic Performance, Functional Movement, Muscle Strength
- Trial name
- NCT07702370
- Testing
- Physical Performance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Spastic Cerebral Palsy, Physical Therapy Modalities
Effectiveness of Whole-Body Vibration
Cerebral Palsy is the most common cause of severe physical disability in childhood and may present difficulties and limitations that will have an impact on their independence and integration in all social areas.
- Conditions
- Spastic Cerebral Palsy, Physical Therapy Modalities, Vibration; Exposure, Lower Extremity Weakness, Spastic
- Trial name
- WBVibration (NCT06330311)
- Testing
- Physiotherapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Muscle Atrophy, Cachexia
Vitamin K2 Supplements for Muscle Recovery
Ankle injury is one of the most common injuries which can have long term consequences. Ankle immobilization is often applied for up to six weeks to ensure healing of the soft tissue and fractured bones after such an injury.
- Trial name
- Recovery (NCT05161975)
- Testing
- Vitamin K2
- Where
- 2 sites in Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Groin Pain
Comparing the Effects of Holmich Protocol Exercise Therapy and Joint Mobilization Training on Pain, Balance, Function of the Lower Limb, and Muscle Activity in Soccer Players with Athletic Groin Pain.
The goal of this clinical trial is comparison the Holmich protocol exercise therapy and joint mobilization training, investigating their respective effects on muscle activity in soccer players with athletic groin pain.
- Trial name
- NCT06831630
- Testing
- Holmich protocol exercise, Joint Mobilization
- Volunteers
- 30 people
- Sponsor
- Yeditepe University
Spinal Cord Injuries, Paraplegia
Multimodal Exercises to Improve Leg Function After Spinal Cord Injury
Many people with spinal cord injury (SCI) retain at least some movement below their injury, but their muscles often have a 'mind of their own'.
- Conditions
- Spinal Cord Injuries, Paraplegia, Paraparesis
- Trial name
- NCT01740128
- Testing
- Robotic body weight supported treadmill training, Harness-supported multimodal balance training
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- VA Office of Research and Development
Anterior Cruciate Ligament Injuries
Perturbation Training vs Functional Activities on Pain, ROM, Balance, and Function Post-ACL
Anterior cruciate ligament (ACL) injuries are among the most common and functionally disabling knee injuries, particularly in physically active individuals.
- Trial name
- NCT07642752
- Testing
- Perturbation Training Group, Task-Oriented Functional Activities Group, Control Group (Standard Rehabilitation Protocol)
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Function, Pain
Comparative Study on Surgical Approaches for Elderly Femoral Neck Fractures
A prospective controlled study was conducted to include patients who received hip replacement surgery for femoral neck fractures at the National Regional Trauma Center in Fujian Province from February 2023 to August 2024.
- Trial name
- NCT06760949
- Testing
- Direct anterior approach hemiarthroplasty, Posterior lateral approach hemiarthroplasty
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Fujian Provincial Hospital
Hemophilia
The Effects of Core Stabilization Exercises in Addition to Balance Exercises in Adult Hemophilia Patients on Balance, Quality of Life, Lower Limb Muscle Strength and Functional Level
The aim of this study is to investigate the effects of core stabilization exercises in addition to balance exercises on balance, quality of life, lower extremity muscle strength and functional level in adult hemophilic patients.
- Trial name
- NCT03574922
- Testing
- Balance exercises, Core Stabilization exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Hacettepe University
Hip Fracture, Disability
Efficacy of a Post-Rehabilitation Exercise Intervention
Background: Many people who have suffered a hip fracture are discharged from rehabilitation services with significant residual functional limitations and disability.
- Trial name
- NCT00592813
- Testing
- Enhanced Strong for Life, cardiovascular nutrition education
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Boston University
Haemodynamic Physiology
Electrical Stimulation of the Muscle Pumps of the Leg
The most efficient way of electrically stimulating the calf muscles has not been identified. The investigators aim to investigate this using a matrix of electrical parameters, and measuring the outcome with vascular ultrasound of…
- Trial name
- Muscle Pump (NCT02532556)
- Testing
- Electrical stimulation (Digitimer)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Patellofemoral Osteoarthritis
Proximal and Distal Therapeutic Approach in Pain and Lower Limb Kinematic in People With Patellofemoral Osteoarthritis
This is a crossover study that will investigate the immediate effects of a proximal therapeutic approach (SERF strap) and a distal one (foot orthoses) on knee pain intensity, global change, symptoms, ease of performance and…
- Trial name
- NCT04332900
- Testing
- Elastic hip strap, Insole
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Sao Carlos
Unilateral Hip Fracture
Improving Functional Recovery After Hip Fracture
This project will assess the effectiveness of a novel approach involving patient education and strength training to improve functional recovery after a hip fracture.
- Trial name
- NCT00000436
- Testing
- Self-efficacy and muscle strength training, High-intensity strength training
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Pes Planus, Diaphragm Issues
The Relationship Between Pes Planus, Diaphragm, Postural Control, and Plantar Pressure
Our primary aim is to compare diaphragm function (resting thickness, activity/resting thickness ratio indicating contractility), postural control, and plantar pressure between individuals with pes planus and healthy controls…
- Conditions
- Pes Planus, Diaphragm Issues, Plantar Pressure, Postural Control
- Trial name
- NCT06491212
- Testing
- Determination of Foot Deformity Level, Foot Function Index, UFAA-International Physical Activity Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University