Clinical trials: Magnetic Resonance Imaging (MRI)
Tetralogy of Fallot
Effect of Contouring Techniques on CMR Assessment of the Right Ventricle in Repaired Tetraology of Fallot
Patients with repaired tetralogy of Fallot (RTOF) develop chronic pulmonary regurgitation and require monitoring for right ventricular dilatation.
- Trial name
- NCT04359940
- Testing
- Cardiac MRI
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Hepatoblastoma, Hepatic Hemangioendothelioma
Deep Learning Magnetic Resonance Imaging Radiomics for Diagnostic Value of Hepatic Tumors in Infants
Hepatic tumors in the perinatal period are associated with significant morbidity and mortality in affected patients. The conventional diagnostic tool, such as alpha-fetoprotein (AFP) shows limited value in diagnosis of infantile…
- Trial name
- NCT05170282
- Testing
- Radiomic Algorithm
- Where
- China
- Volunteers
- 200 people
- Sponsor
- West China Hospital
Multiple Sclerosis
Magnetic Resonance Imaging (MRI) Follow-up of Macrophagic Infiltration in MS Patients Treated With Tysabri
To evaluate the diagnosis value of MRI and positon emission tomography (PET) scan for studying macrophagic infiltration and other brain modification in multiple sclerosis (MS) patients treated with Natalizumab (Tysabri).
- Trial name
- NCT00752778
- Testing
- pet-scan FDG-F18
- Where
- 3 sites in France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Strasbourg, France
Nonalcoholic Steatohepatitis
Predictable MR Index for Nonalcoholic Steatohepatitis (NASH)
1. To evaluate feasibility of using multiparametric Magnetic resonance(MR) imaging to predict nonalcoholic steatohepatitis(NASH) 2.
- Trial name
- NCT03375008
- Testing
- Imaging diagnostic and biopsy
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Korea University Guro Hospital
Relapsing Remitting Multiple Sclerosis
Advanced MRI Measures of Repair in Alemtuzumab Treated Patients
There are two parts to this investigator sponsored trial (IST): 1. To perform advanced serial MRI studies on patients initiating alemtuzumab therapy. 2.
- Trial name
- iCAMMS-IST (NCT01307332)
- Testing
- MabCampath-1h
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of British Columbia
Primary Central Nervous System Lymphoma
[18F]-Fludarabine PET/MRI in Primary Central Nervous System Lymphoma
Primary central nervous system (CNS) lymphomas represent 5% of primary brain tumors. More than 90% of them are diffuse large B-cell lymphomas.
- Trial name
- FLUDALOC (NCT05390814)
- Testing
- PET-MRI
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cholesteatoma
Magnetic Resonance (MR) Imaging in the Post Operative Follow-up of Cholesteatoma in Children
Classical imaging techniques are inaccurate to detect residual cholesteatoma. The aim of our study is to evaluate the value of diffusion-weighted MR imaging and delayed contrast enhanced T1 weighted spin-echo sequences in the…
- Trial name
- NCT00682409
- Testing
- MR Imaging
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Breast Cancer, Lymphoma, Large B-Cell, Diffuse
Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With Anthracyclines
As the cancer-related prognosis improves thanks to recent advances in cancer-targeted therapies, the prognostic burden of chemotherapy-related complications - including cardiotoxicity - is increasingly recognised.
- Conditions
- Breast Cancer, Lymphoma, Large B-Cell, Diffuse, Cardiotoxicity, Left Ventricular Dysfunction
- Trial name
- CONTROL (NCT05728632)
- Testing
- Nebivolol
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Giulio Stefanini
Obstructing Colorectal Cancer
Preoperative Assessment for Synchronous Carcinoma or Polyps With Magnetic Resonance (MR) Colonography
The purpose of this study is to diagnose possible synchronous carcinomas and polyps with magnetic resonance (MR) colonography in patients booked for operation because of carcinoma in the descending or sigmoid colon, where a…
- Trial name
- NCT00300547
- Testing
- MR colonography
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Herlev Hospital
Glioblastoma, Glioma
Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide
The purpose of this study is to learn whether 3 tesla (3T) MRI functional imaging will map a tumor more accurately allowing a more targeted delivery of radiation.
- Trial name
- NCT00250211
- Testing
- Functional MRI imaging and tomotherapy
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- AHS Cancer Control Alberta
Depression
Depression, Adversity, and Stress Hormones (DASH) Study
The stress-related hormone cortisol has been studied in depression for decades. However, relatively little is known about the role of cortisol in psychological features of depression.
- Trial name
- DASH (NCT03195933)
- Testing
- Cortisol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Lung Cancer, Prostate Cancer
Soft Tissue Detection on MRI, Cone Beam CT and Fan Beam CT and Integration of Functional MRI
This clinical trial studies magnetic resonance imaging (MRI), cone beam computed tomography (CT), and fan beam CT in detecting soft tissue in patients with prostate and lung cancer undergoing radiation therapy.
- Trial name
- NCT01859338
- Testing
- cone-beam computed tomography, magnetic resonance imaging, computed tomography
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Virginia Commonwealth University
Multiple Sclerosis, Relapsing-Remitting
Cognition and MRI Markers in MS Patients With Aubagio® Treatment
Cognitive impairment is nowadays more and more recognized as an important feature of the multiple sclerosis (MS) disease which contributes largely to disability.
- Trial name
- AUBACOG (NCT03768648)
- Testing
- Clinical assessment, Ecological evaluation, Neuropsychological evaluation
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Locally Advanced Pancreatic Adenocarcinoma
Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
The aim of this study is to demonstrate the efficacy of intensified and sequential chemotherapy (Gabrinox) comprising Gembrax regimen (Gemcitabine-Abraxane) followed by the Folfirinox regimen (5FU, Oxaliplatin and Irinotecan) in…
- Trial name
- GABRINOX-ART (NCT04570943)
- Testing
- Gabrinox, MRI-GUIDED STEREOTACTIC RADIOTHERAPY
- Where
- 9 sites in France
- Volunteers
- 103 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Wrist Internal Derangement, Triangular Fibrocartilage Complex Tears
Added Diagnostic Value of CT Arthrography to MR Arthrography in Wrist Internal Derangement
The wrist is a complex joint made up of small bones, cartilage, and stabilizing ligaments, including the triangular fibrocartilage complex (TFCC) and intrinsic carpal ligaments.
- Conditions
- Wrist Internal Derangement, Triangular Fibrocartilage Complex Tears, Scapholunate Ligament Tears, Lunotriquetral Ligament Tears
- Trial name
- NCT07826208
- Testing
- Combined CT Arthrography and MR Arthrography
- Volunteers
- 60 people
- Sponsor
- Assiut University
Breast Cancer, BRCA1 Mutation
3.0 Tesla Magnetic Resonance Imaging for Breast Cancer Detection in High Risk Women
This study is to find out if 3.0 Tesla (3.0-T) Magnetic Resonance Imaging (MRI) will improve in diagnosing breast cancer in women with high-risk of breast cancer.
- Conditions
- Breast Cancer, BRCA1 Mutation, BRCA2 Mutation
- Trial name
- NCT01409226
- Testing
- 3.0-T MRI, biopsy
- Where
- United States
- Sponsor
- NYU Langone Health
Bipolar Affective Disorder
Bipolar Research Study Using MR Imaging
In this proposal, the investigators will focus on subcortical gray and white matter structures commonly found to be abnormal in schizophrenia.
- Trial name
- NCT02083978
- Testing
- MRI scanning
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Washington University Early Recognition Center
Cocaine-Related Disorders, Opioid-Related Disorders
Phase I Functional Magnetic Resonance Imaging (fMRI) Pharmacodynamic Studies of Compounds for Opioid Use Disorder and Cocaine Use Disorder
The purpose of Project 2 is to execute phase I functional magnetic resonance imaging (fMRI) studies to assess the effects of lorcaserin on brain target engagement (measured by fMRI brain activation and neural connectivity) in…
- Trial name
- NCT03143543
- Testing
- Group A Lorcaserin (10mg), Group A2 Lorcaserin (20 mg)
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Virginia Commonwealth University
Chronic Migraine
Hypothalamus Connectivity in Chronic and Episodic Migraine
The purpose is to compare, using functional magnetic resonance imagery in resting-state, the connectivity of the hypothalamus in 2 groups of migraineurs.
- Trial name
- HYPOTHAMIG (NCT02328976)
- Testing
- functional Magnetic Resonance Imaging (fMRI)
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Toulouse
Muscle Invasive Bladder Cancer
A Novel Pathway to Detect Muscle-invasive Bladder Cancer Based on Integrated Clinical Features and VI-RADS Score on MRI
This study investigates the clinical, pathological, and radiological features, including the Vesical Imaging-Reporting and Data System (VI-RADS) score, that correlate with muscle-invasive bladder cancer (MIBC).
- Trial name
- VI-RADS (NCT06807008)
- Where
- 4 sites in Italy
- Volunteers
- 139 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
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