Clinical trials: Malignant Neoplasm of Abdomen
Abdominal Tumor, Abdominal Infection
Evaluation of Pcv-aCO2 in the Fluid Treatment of Abdominal Tumor Patients After Surgery
This research will confirm that Pcv-aCO2 is suitable for the guidance of early fluid therapy and the evaluation of the prognosis of patients with abnormal hemodynamics after abdominal tumor surgery, and is expected to be a new…
- Trial name
- NCT02977429
- Testing
- standardized fluid therapy, conventional fluid therapy
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Advanced Breast Carcinoma, Advanced Endometrial Carcinoma
Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax
This phase Ib trial tests the safety, side effects, and best dose of tumor treating fields therapy in combination with either cabozantinib or nab-paclitaxel and atezolizumab in treating patients with solid tumors involving the…
- Conditions
- Advanced Breast Carcinoma, Advanced Endometrial Carcinoma, Advanced Fallopian Tube Carcinoma, Advanced Hepatocellular Carcinoma
- Trial name
- NCT05092373
- Testing
- Atezolizumab, Cabozantinib S-malate, Nab-paclitaxel
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- M.D. Anderson Cancer Center
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Digital Meditation for Postoperative Pain Control After Abdominal Surgery for Cancer
This phase I trial tests a digital meditation for postoperative pain control after abdominal surgery for cancer. Mindfulness interventions such as guided meditation may improve pain control and decrease stress.
- Trial name
- NCT05346692
- Testing
- Survey Administration, Interview, Text Message-Based Navigation Intervention
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Emory University
Intrathecal Dexmedetomidine, Pediatric Cancer Surgery
Intrathecal Dexmedetomidine Versus Fentanyl With Bupivacaine in Children Undergoing Major Abdominal Cancer Surgery
In this study the investigators aim to determine the analgesic effect and side effects of intrathecal fentanyl and dexmedetomidine as adjuvant to local anesthetics in pediatric patients undergoing major abdominal cancer surgeries.
- Trial name
- NCT02861716
- Testing
- Bupivacaine, Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Peritoneum Cancer, Peritoneum Neoplasm
International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)
Multicentric, international, web-based prospective documentation of the indications and results of Pressurized Aerosol Chemotherapy (so-called PIPAC or PITAC) for treating malignant pleural and peritoneal diseases.
- Conditions
- Peritoneum Cancer, Peritoneum Neoplasm, Pleural Cancer, Pleural Effusion
- Trial name
- PIPACRegis (NCT03210298)
- Testing
- PIPAC
- Where
- 16 sites in Argentina, Australia and 11 more
- Volunteers
- 1,000 people
- Sponsor
- Sabine Rhode
Head and Neck Cancer, Lung Cancer
Evaluation of a Cone-beam CT Scanner for Image Guided Radiotherapy
This is a feasibility study investigating the image quality of a new, high-performance cone beam CT (CBCT) used for on-couch imaging during radiotherapy treatments.
- Conditions
- Head and Neck Cancer, Lung Cancer, Breast Cancer, Abdominal Cancer
- Trial name
- CONFIGURE (NCT05524454)
- Testing
- Novel CBCT Imaging
- Where
- Netherlands
- Volunteers
- 41 people
- Sponsor
- Varian, a Siemens Healthineers Company
Peritoneal Neoplasms, Ascites
Local mEHT + TCM Versus Intraperitoneal Chemoinfusion in Treatment of Malignant Ascites: Phase II RCT
This trial studies efficacy and safety of combination of modulated electro-hyperthermia (mEHT) with Traditional Chinese Medicine (TCM) in treatment of peritoneal carcinomatosis with malignant ascites versus standard chemoinfusion…
- Conditions
- Peritoneal Neoplasms, Ascites, Yang Deficiency, Yin Deficiency
- Trial name
- OTMA-RII (NCT02638051)
- Testing
- Modulated Electro-Hyperthermia (mEHT), TCM Herbal Decoction (Shi Pi), IPCI (CDDP+5FU)
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Galenic Research Institute Ltd
Malignant Mesothelioma
Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Peritoneal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving the drugs directly into the tumor after surgery and combining them with radiation therapy may kill…
- Trial name
- NCT00024271
- Testing
- recombinant interferon gamma, cisplatin, doxorubicin hydrochloride
- Where
- United States
- Sponsor
- Herbert Irving Comprehensive Cancer Center
Pelvic Cancer, Abdominal Cancer
IV Contrast-Enhanced Cone Beam Computed Tomography (CBCT) in Radiotherapy
The purpose of this study is to find out if giving intravenous (IV) contrast (a liquid that helps with the visibility of organs and blood vessels that is given through the vein with the use of a hollow needle) during a Cone Beam…
- Trial name
- NCT04199754
- Testing
- Omnipaque 300mg/mL Solution for Injection, Cone Beam CT, Radiation Therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Columbia University
Central Thorax Cancer, Liver Cancer
Adaptive MRI-Guided SBRT for Unresectable Primary or Oligometastatic Central Thorax and Abdominal Malignancies
The purpose of this research study is evaluate whether it's feasible to give radiation therapy using an MRI-guided adaptive technique.
- Conditions
- Central Thorax Cancer, Liver Cancer, Non-Liver Abdominal Cancer
- Trial name
- NCT02264886
- Testing
- MRI-guided stereotactive body radiation therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Post Operative Pain
Two Doses of Dexmedetomidine as Adjuvent to Bupivacaine in Tap Block
The aim of this study to determine the optimal dose of dexmedetomidine as an adjuvant to bupivacaine in U.S guided TAP block for preemptive analgesia In patients undergoing lower abdominal cancer surgeries.
- Trial name
- Dexmed/tap (NCT06624319)
- Testing
- Dexmedetomidine as adjuvent to bupvacaine in tap block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Subcostal, Lateral
Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery
This study aims to evaluate the safety and efficacy of combined subcostal and lateral transversus abdominis plane (TAP) for postoperative analgesia versus thoracic epidural anesthesia (TEA) in patients undergoing major abdominal…
- Conditions
- Subcostal, Lateral, Transversus Abdominis Plane Block, Postoperative Analgesia
- Trial name
- NCT07273136
- Testing
- Subcostal and lateral transversus abdominis plane block, Thoracic epidural anesthesia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Age Problem, Abdominal Cancer
Dosage of Epidural Morphine in Elderly Patients
This a clinical trial that evaluates the efficacy and safety of three different doses of morphine, namely 1.5 mg, 3 mg and 4.5 mg, via the epidural route regarding reducing pain in elderly patients after a cancer surgery in the…
- Trial name
- NCT04316871
- Testing
- 1.5 mg of Morphine Sulfate, Normal saline, 3 mg of Morphine Sulfate
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Assiut University
Thyroid Neoplasm, Thyroid Carcinoma
Clinical Evaluation of 18F-DOPA Positron Emission Tomography in Medullary Thyroid Cancer
Medullary thyroid carcinoma (MTC) is a rare tumor arising from C cells of the thyroid gland and belonging to the endocrine tumors.
- Conditions
- Thyroid Neoplasm, Thyroid Carcinoma, Medullary Carcinoma
- Trial name
- DOPMET (NCT00647140)
- Testing
- 18F-L-DOPA PET
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Peritoneal Cancer, Peritoneal Metastases
The PIPAC-OPC7 Study: The Use of PET/CT Scans as a Method of Evaluation in Patients Treated With PIPAC, a Pilot Study.
The pilot study will investigate the use of repeated FDG-PET/CT scans in 16 patients with peritoneal metastasis originating from abdominal cancers treated with Pressurized Intraperitoneal Aerosol Chemotherapy.
- Conditions
- Peritoneal Cancer, Peritoneal Metastases, Peritoneal Carcinomatosis, Abdominal Cancer
- Trial name
- NCT06144853
- Testing
- scan
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- Odense University Hospital
Peritoneal Mesothelioma, Peritoneal Carcinomatosis
Treatment of Malignant Peritoneal Mesothelioma (MESOTIP)
MESOTIP is a randomized trial evaluating the association of PIPAC and systemic chemotherapy versus systemic chemotherapy alone as 1st-line treatment of Malignant Peritoneal Mesothelioma In this study, patients in the experimental…
- Trial name
- MESOTIP (NCT03875144)
- Testing
- PIPAC, Cisplatin, Pemetrexed
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Cancer, Malignant Tumors, Abdominal Cancer
Neurolytic Block Techniques In Abdominal Visceral Cancer Pain
The neurolytic blocks of sympathetic chains are commonly used for the treatment of cancer-related pain. This study aims to compare celiac plexus neurolysis and splanchnic nerve neurolysis for the treatment of abdominal visceral…
- Conditions
- Cancer, Malignant Tumors, Abdominal Cancer, Cancer Pain, Visceral Pain
- Trial name
- CONCERN (NCT06978673)
- Testing
- Splanchnic nerve neurolysis - 5 ml of absolute alcohol (100%), Celiac Plexus Neurolysis - 5 ml of absolute alcohol (100%)
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Surgery, Perioperative Care
Restricted Intravenous Fluid Regime Effects on Immunological Indicators of Elderly Patients Operated for Abdominal Cancer
The purpose of this study is to find out whether perioperative fluid restriction influence on postoperative immunological function. And discuss the probable mechanism that fluid restriction regime effect on clinical data.
- Conditions
- Surgery, Perioperative Care, Immunization, Abdominal Neoplasms
- Trial name
- NCT01399814
- Testing
- perioperative fluid management, perioperative fluid treatment
- Volunteers
- 179 people
- Sponsor
- Nanjing PLA General Hospital
Abdominal Cancer
Trial of Perioperative Tadalafil and Influenza Vaccination in Cancer Patients Undergoing Major Surgical Resection of a Primary Abdominal Malignancy
The purpose of this study is to determine if giving Cialis for 5 days prior to surgery, on the day of surgery along with the influenza vaccine and Cialis 10 days after surgery will have an affect at the cell level for decreasing…
- Trial name
- PERIOP-04 (NCT02998736)
- Testing
- Cialis, Influenza vaccine
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Ottawa Hospital Research Institute
Quality of Life, Surgery
Quality of Life and High-Risk Abdominal Cancer Surgery
The investigators plan to measure the changes of health-related quality of life (HRQoL) at 6 months and 12 months after the following high-risk oncological abdominal surgery: gastrectomy, esophagectomy, pancreatectomy and…
- Conditions
- Quality of Life, Surgery, Cancer, Frailty
- Trial name
- ChangeQoL (NCT04444544)
- Testing
- High Risk Abdominal Surgery
- Where
- Switzerland
- Volunteers
- 295 people
- Sponsor
- University Hospital, Geneva