Clinical trials: Microbiological Study
Microbial Colonization
The Influence of Endurance Sports Activity on the Oral Microbiota of Young Adults.
The oral cavity is an easily accessible anatomical site that accurately reflects the health of the individual. The mouth is considered an early indicator of biological aging, leading to the identification of oral biomarkers…
- Trial name
- ORAMICAP (NCT05765422)
- Testing
- salivar and gum sampling
- Where
- France
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Gingivitis and Periodontal Diseases, Tooth Loss
Cement Excess at Single Implant Crowns Malmö/Lund
Abstract Aim: The primary aim of this study is to test whether or not cement residues in the submucosal environment of implants lead to a change in the microbiota and induce inflammation of the periimplant tissues.
- Trial name
- NCT04015427
- Testing
- implant crown
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Bacterial Contamination
Bacterial Mask Contamination in Operating Room
The primary objective of this study is to determine whether surgical mask configuration policy-compliant (up or off ) versus mask dangling is associated with differences in bacterial contamination among unscrubbed operating room…
- Trial name
- NCT07900958
- Testing
- Mask up or off, Mask dangling
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Chronic Periodontitis
Effect of the Diode Laser on Bacteremia Associated With Periodontal Flap Surgery: A Clinico-Microbiological Study
The objective of the present study is 1. To study the incidence and magnitude of bacteremia after periodontal flap surgery . 2. To compare and evaluate the effect of diode laser on frequency of bacteremia associated with…
- Trial name
- NCT04207034
- Testing
- flap surgery with diode laser, flap surgery
- Where
- India
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Chronic Periodontitis
Decontaminant Agent in the Treatment of Chronic Periodontitis
In light of the controversy that are already approved but that however still exists regarding the efficacy and influence of the decontaminant tools for the management of Chronic Periodontitis (cp), the aim of this study was to…
- Trial name
- NCT02657096
- Testing
- Hybenx treatment (device), Scaling and Root Planing (SRP)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Messina
Periodontal Disease
Study on Biomarkers of Periodontitis and Type 2 Diabetes Mellitus in Males and Females 30 - 70 Years of Age
The purpose of this study is to learn about the interactions of markers of type 2 diabetes (T2DM) and periodontitis (PD). Study VPE00001 is a multi-center cross-sectional study.
- Trial name
- NCT06582056
- Testing
- Investigational Procedure
- Where
- 4 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Peri-implant Mucositis, Peri-Implantitis
The Effect of Different Dental Implant Surface Characteristics on Immunological and Microbiological Parameters
Objectives: To assess the levels of TNF-α, PGE2, RANKL, RANK, OPG, which are immunological markers of peri-implant disease and F. nucleatum, P. gingivalis, T. denticola, T. forsythia, P. intermedia, S.
- Trial name
- NCT03693196
- Testing
- PICF, Perio-paper®, Subgingival Plaque, Hu-Friedy®, Williams probe, PCPNU-15 Hu-Friedy®
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Chronic Periodontitis
Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis
This study was carried out in the Department of Periodontology and source of patient was be from the outpatient section of Tatyasaheb Kore Dental College \& Research Centre, New Pargaon.
- Trial name
- NCT03516370
- Testing
- Saccharomyces Boulardii 250 MG
- Where
- India
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Periodontitis, Adult
Locally Delivered Minocycline in Advanced Periodontitis
Local drug delivery provides higher concentrations in the availability of the drug at the specific infected sites with the advantage of sustained release.
- Trial name
- NCT04076098
- Testing
- Minocycline Hydrochloride
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahsa University
Candidiasis, Vulvovaginal
Epidemiological Study About the Evolution of Patients Treated for an Acute Episode of Vulvovaginal Candidiasis
To determine proportion of women achieving clinical and mycological cure or have recurrences / reinfection after being treated for an acute episode of vulvovaginal candidiasis.
- Trial name
- NCT02248506
- Testing
- Clotrimazole
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Instituto Palacios
Nervous System Lyme Borreliosis
Study on Early Lyme Neuroborreliosis
The purpose of this study is to determine clinical course and the sequelae of early Lyme neuroborreliosis after treatment with ceftriaxone.
- Trial name
- NCT00910533
- Testing
- ceftriaxone
- Where
- Slovenia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Peri-implant Mucositis
A Topical Desiccant Agent in Association With Manual Debridement in the Treatment of Peri-implant Mucositis
In patients presenting peri-implant mucositis, effective sub-mucosal debridement is crucial to prevent peri-implantitis. The aim of this pilot study was to assess the 3-month clinical and microbiological effects of a locally…
- Trial name
- NCT03858959
- Testing
- topical agent
- Where
- Italy
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Periodontitis, Alzheimer Disease
Oral Bacterial and Viral Mapping by Dental Plaque in Elderly Patients With and Without Alzheimer's Disease(ORal MICrobiology in Alzheimer's Patients)
The neurological disorders that accompany aging represent a major public health problem. The management of these diseases is a major medical and social priority.
- Trial name
- ORAMICAL (NCT04869904)
- Testing
- dental and plaque sampling
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chronic Periodontitis
Perio. Maint. With Diode LBR
The primary aim of this pilot study is to determine whether the test methods described feasibly achieve the goal defined for a future clinical study.
- Trial name
- NCT05276817
- Testing
- Epic Diode, HP
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Biolase Inc
Dental Implant Failed
Clinical, Prospective, Non-profit, Non-pharmacological Study on Geass Healing Abutment: Microbiological, Histological, and Immuno-histochemical Evaluation.
The health of peri-implant soft tissues is important for the long-term success rate of dental implants and the surface topography is pivotal in influencing it.
- Trial name
- NCT05754970
- Testing
- laser treated
- Where
- Italy
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Periodontal Pocket
Ozonized Olive Oil in the Treatment of Periodontal Pockets
A randomized controlled clinical trial was conducted on 16 patients (8 males and 8 women) who were diagnosed chronic periodontitis.
- Trial name
- NCT06980675
- Testing
- Activated Ozonized Olive Oil Gel
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari
Severe Pneumonia, Bacterial Infections
Diagnostic Application of AI-ROSE in Severe Pneumonia
AI-ROSE is an innovative immunofluorescence staining combined with artificial intelligence image analysis technology that uses a fully automated fluorescence microscope to image pathogens in real time.
- Trial name
- NCT07113951
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Peridontal Disease
Efficacy of Injectable Platelet-rich Fibrin Versus Platelet-Rich Plasma As Adjunctive to Scaling and Root Planning in Non-surgical Periodontal Therapy of Periodontitis Patients
The study aims to evaluate the Efficacy of Injectable Platelet-rich Fibrin versus Platelet-Rich Plasma as adjunctive to scaling and root planning in non-surgical periodontal therapy of Periodontitis patients (Randomized…
- Trial name
- PRP-IPRF (NCT06685393)
- Testing
- Platelet rich plasma (PRP), INJECTABLE PLATELET RICH FIBRIN(I-PRF)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ELsabbahy Ahmed Mohamed Youssef
Dental Caries
Phase 2, Safety & Microbiology Study of C16G2 in Multiple Oral Gel &/or Mouth Rinse Doses to Healthy Adults
The focus of the study is to evaluate the safety of multiple study drug administrations and the study drug selectively reducing or eliminating a specific bacteria in the mouth.
- Trial name
- NCT02044081
- Testing
- C16G2 Rinse, C16G2 Gel
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Armata Pharmaceuticals, Inc.
Dental Caries
A Phase 2 Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Varnish and Strip in Adolescent and Adult Subjects
An open-label and single-blind phase 2 study to evaluate the oral microbiology, safety and tolerability of multiple C16G2 Varnish and Strip applications in male and female dental subjects 12-75 years of age.
- Trial name
- C3J17-206-00 (NCT03196219)
- Testing
- C16G2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Armata Pharmaceuticals, Inc.