Clinical trials: Minimally Invasive Treatment
Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy
Clinical Study of Double-Endoscopic Combined With Minimally Invasive Treatment for Early Gastric Cancer at Clinical Stage T1b
For patients diagnosed with early gastric cancer involving submucosal invasion, super-ESD indications, or lymph node metastasis, a combination of preoperative endoscopic ultrasound and abdominal contrast-enhanced CT was utilized…
- Trial name
- NCT06934824
- Testing
- Sixty patients with early gastric cancer in stage T1bN0-1M0 were divided into Group A-N0 and Group B-N + according to the presence or absence of lymph node metastasis. When the enrolled patients und
- Volunteers
- 60 people
- Sponsor
- Hebei Medical University
Renal Cancer
Study of Minimally-invasive Ablative Renal Therapies (SMART) Registry
Multi-center prospective cohort study examining curative intent renal cryotherapy and radiofrequency ablation for small renal mass treatment in patients who are poor candidates for surgical resection, We will capture clinical…
- Trial name
- SMART (NCT05210933)
- Where
- 2 sites in Canada
- Volunteers
- 750 people
- Sponsor
- University of Alberta
GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Comparing XEN®-63 Gel Stent and PRESERFLO® MicroShunt
The goal of this randomized controlled clinical trial is to learn whether two minimally invasive bleb-forming glaucoma implants can effectively treat adult patients with open-angle glaucoma who require surgical lowering of…
- Trial name
- MINI-BATTLE (NCT07359547)
- Testing
- XEN®-63 Gel Stent, PRESERFLO™ MicroShunt
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 166 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Clarify the Therapeutic Differences Between Robot Assisted Endoscopic Clearance and Traditional Puncture and External Drainag
Effect of Minimally Invasive Surgical Assisted by Robots on Intraventricular Hemorrhage
Clarify the therapeutic differences between robot assisted endoscopic clearance and traditional puncture and external drainage, and establish a new minimally invasive surgical diagnosis and treatment strategy for intraventricular…
- Trial name
- NCT06486480
- Testing
- Using robot assisted endoscopy to clear intraventricular hemorrhage
- Volunteers
- 143 people
- Sponsor
- Jin Hu
Esophageal Cancer (EsC), Postoperative Pulmonary Complications (PPCs)
Effect of VExUS Score on Postoperative Pulmonary Complications in Elderly Patients
Brief Summary This clinical trial aims to evaluate whether perioperative goal-directed fluid therapy (GDFT) targeting a venous excess ultrasound (VExUS) score of 1 can reduce postoperative pulmonary complications (PPCs) in…
- Trial name
- NCT07691944
- Testing
- VExUS Score-Guided Intraoperative Goal-Directed Fluid Therapy
- Volunteers
- 126 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Epistaxis
Minimally Invasive Control of Epistaxis (MICE)
Epistaxis is a common disorder with 60% of the population suffering from one episode and 10% of these cases requiring medical attention.
- Trial name
- MICE (NCT00666471)
- Testing
- MICE, SPA ligation
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of Calgary
Intervertebral Disc Degeneration
5-Year Global Study on MAST™ Minimally Invasive Fusion Procedures to Treat Degenerative Lumbar Spine (MASTERS-D2)
The purpose of this study is to evaluate the effectiveness of MAST techniques for anterior/lateral and posterior approaches in Degenerative Disc Disease (DDD) patients with spondylolisthesis (≥ grade I).
- Trial name
- MASTERS-D2 (NCT02617563)
- Testing
- Minimally invasive lumbar fusion
- Where
- 27 sites in Argentina, Austria and 15 more
- Volunteers
- 361 people
- Sponsor
- Medtronic Spinal and Biologics
Prostate Cancer
Efficacy,Safety and Quality of Life After TOOKAD® Soluble VTP for Localized Prostate Cancer
The aim of this study is to confirm the Efficacy,the Safety and the Quality of Life after TOOKAD® Soluble VTP in localized prostate cancer patients.
- Trial name
- PCM304 (NCT01875393)
- Testing
- TOOKAD® Soluble
- Where
- 3 sites in Mexico, Panama and 1 more
- Volunteers
- 81 people
- Sponsor
- Steba Biotech S.A.
Periodontal Intrabony Defect
Impact of Minimally Invasive Non-surgical Periodontal Treatment on Infrabony Defects
Fifty-two periodontitis patients (26 per group) were randomly assigned to the test (Minimally invasive non-surgical therapy - MINST) or the control group (Quadrantwise Subgingival Instrumentation - Q-SI) NPT protocols.
- Trial name
- Infra-MINST (NCT06992219)
- Testing
- Non surgical periodontal treatment evaluated through probing pocket depth reduction
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Catania
Functional Mitral Regurgitation
Evaluation of the Minimally Invasive VenTouch™ System in the Treatment of Functional Mitral Valve Regurgitation (FMR)
This is a prospective, multi-center, single-arm study to evaluate the VenTouch System for treatment of moderate to moderate-severe functional mitral valve regurgitation [FMR].
- Trial name
- NCT02671799
- Testing
- VenTouch System Implant
- Where
- 2 sites in Czechia, France
- Volunteers
- 15 people
- Sponsor
- Mardil Medical
Severe Sepsis, Septic Shock
Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock
Early intervention in the treatment of septic shock, including early goal-directed therapy (EGDT) in the first 6 hours of disease presentation, has been shown to significantly decrease mortality.
- Trial name
- MiCHO (NCT00535821)
- Testing
- Esophageal Doppler monitoring - CardioQ, Deltex Inc, Central line with CVP and continuous ScvO2 monitoring
- Where
- 4 sites in United States
- Volunteers
- 5 people
- Sponsor
- Loma Linda University
Esophageal Achalasia, Esophageal Motility Disorders
POEM Versus Laparoscopic Heller Myotomy With Dor Fundoplication for Esophageal Achalasia
Achalasia is a disorder of the esophagus in which the muscular valve between the esophagus and the stomach fails to relax, and the body of the esophagus loses its normal coordinated squeezing movement.
- Conditions
- Esophageal Achalasia, Esophageal Motility Disorders, Gastroesophageal Reflux
- Trial name
- POEM-HD (NCT07814027)
- Testing
- Peroral endoscopic myotomy, Laparoscopic Heller myotomy with Dor fundoplication
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Minia University
Lung Neoplasms, Non-Small Cell Lung Cancer, Postoperative Complications
Smartphone-based Remote Symptom Monitoring to Improve Postoperative Rehabilitation Exercise Adherence After Video-assisted Thoracic Surgery (VATS) for Lung Cancer
Brief Summary: This randomized controlled trial aims to evaluate whether active remote symptom monitoring and management via a smartphone app utilizing electronic patient-reported outcomes (ePRO) can improve adherence to…
- Conditions
- Lung Neoplasms, Non-Small Cell Lung Cancer, Postoperative Complications, Patient Reported Outcome Measures, Telerehabilitation
- Trial name
- NCT05990946
- Testing
- ePRO based Remote Symptom Management provide by a mobile phone app
- Where
- China
- Volunteers
- 736 people
- Sponsor
- Zhongshan People's Hospital, Guangdong, China
Healthy
Technical Development of Interventional Cardiovascular Magnetic Resonance Imaging in Normal Volunteers
This study will test new techniques to image the heart, blood vessels, and legs using magnetic resonance imaging (MRI). The techniques will be used to plan and guide treatments using minimally invasive methods.
- Trial name
- NCT00720460
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Metastatic Cancer
Conventional or Video-Assisted Surgery in Treating Patients With Lung Metastases
RATIONALE: Video-assisted surgery may have fewer side effects than conventional surgery in patients with lung metastases. It is not yet known whether conventional surgery or video-assisted surgery is more effective in treating…
- Trial name
- NCT00003724
- Testing
- surgical procedure
- Where
- 45 sites in United States
- Volunteers
- 530 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Periodontal Diseases, Periodontitis
Inflammation-resolution Therapy in MINST of Periodontal Intrabony Defect: a Pilot Randomised Controlled Trial
The aim of this study is to assess whether and how a mouthwash containing an ingredient that reduces inflammation in combination with a recently developed treatment is more effective at improving advanced gum disease.
- Trial name
- AIRTIM (NCT07203872)
- Testing
- IsoDent Paro Strong (Isodent Ltd. Valtakatu 4 D, 96100 Rovaniemi, Finland) mouthwash
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Benign Prostatic Hyperplasia
Transperineal Irreversible Electroporation for Benign Prostatic Hyperplasia
This clinical trial focuses on men with benign prostatic hyperplasia (BPH), a condition in which an enlarged prostate causes urinary problems.
- Trial name
- NCT06867315
- Testing
- Composite steep-pulse therapeutic device (CNP-III)
- Where
- 10 sites in China
- Volunteers
- 99 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Supracondylar Femoral Fractures, Femoral Fractures
Robot-Assisted Closed Reduction and Internal Fixation for Distal Femoral Fractures
This study aims to evaluate the clinical efficacy and safety of an intelligent robotic system for the closed reduction of extra-articular supracondylar femoral fractures (Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic…
- Trial name
- NCT07738406
- Testing
- Robot-assisted closed reduction, Conventional fracture reduction and internal fixation
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Beijing Jishuitan Hospital
Esophageal Squamous Cell Carcinoma
Study of Neoadjuvant Nivolumab or Placebo Plus Chemotherapy Followed by Surgery and Adjuvant Treatment in Subjects With Resectable ESCC
Esophageal cancer, the 7th most common cancer globally, accounts for more than half a million deaths each year. The incidence of ESCC, the most common histologic type, has been stable, whereas the incidences of esophageal and…
- Trial name
- NCT05213312
- Testing
- Nivolumab, Cisplatin, Paclitaxel
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Zhongshan Hospital
Hysterectomy, Goal Achievement
Goal Achievement and Patient Satisfaction in Benign Hysterectomy
This study evaluates patient goal achievement and satisfaction in benign hysterectomy. Patient's will state their goals prior to undergoing benign hysterectomy, and will receive a follow-up questionnaire 3 months post-operatively…
- Conditions
- Hysterectomy, Goal Achievement, Patient Satisfaction, Minimally Invasive Surgery
- Trial name
- NCT02621710
- Testing
- Questionnaire 3 months post-operatively
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center