Clinical trials: Modification
Old Age; Debility, Psychological Distress
Mindfulness-based Short Intervention for Seniors - Decentering Effects on Cognitive Functions and Psychological Distress
The present study examined the effect of a short Mindfulness-based intervention emphasizing a 'decentering' component on elderly seniors.
- Conditions
- Old Age; Debility, Psychological Distress, Cognitive Change
- Trial name
- NCT04165005
- Testing
- decentering, guided imagery
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ben-Gurion University of the Negev
Breast Cancer Prevention
MELIORA Data Collection Campaigns
To support the development of the MELIORA digital app for the MELIORA main intervention, an initial pilot study (Data Collection Campaign, DCC) is being conducted with the three target participant groups: healthy women at…
- Trial name
- DCC (NCT07190066)
- Testing
- Data Collection campaign
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Non-Metastatic Breast Cancer
Study of Chemotherapy-Induced Hair Changes and Alopecia, Skin Aging and Nail Changes in Women With Non-Metastatic Breast Cancer
The purpose of this study is to see how many patients develop hair, skin and nail changes due to cancer treatments. The investigators would like to study the clinical factors, genetic markers, and impact on patients'…
- Trial name
- NCT02530177
- Testing
- Clinical Assessments, Questionnaires, Saliva sample
- Where
- United States
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Overweight and Obesity
Could a Time-restricted Diet Compete With a Calorie-restricted 6-meal Diet?
The prevalence of obesity and obesity-related diseases are on the rise worldwide. The widely accepted approach in dietary treatment of obesity is the calorie-restricted three meals-three snacks a day diet; however, alternative…
- Trial name
- NCT06364475
- Testing
- 16:8 Time-Restricted Intermittent Fasting Group, Energy-Restricted Six-Meal Group
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Cardiovascular Disease, Dyslipidemia
The Mediterranean Full-Fat Dairy Study
A Mediterranean dietary pattern emphasizing an abundance of plant-based foods including nuts, moderate intakes of fish, poultry and low-fat dairy products, and use of extra virgin olive oil as the main source of fat has been…
- Conditions
- Cardiovascular Disease, Dyslipidemia, Inflammation
- Trial name
- MFFD (NCT02781675)
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Sleep Disturbance, Cognitive Change
Integrating Systematic Data of Geriatric Medicine to Explore the Solution for Health Aging
This project aims to build up the comprehensive database of geriatric medicine for local Taiwanese.
- Conditions
- Sleep Disturbance, Cognitive Change, Aging
- Trial name
- NCT04207502
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Therapy, Exercise
Changes in Attention Level Due to Isometric Exercises and Level Three Progression Eccentric Movements
Determine the changes in attention level due to isometric exercises and level three progression eccentric movements. The attention level will be measured using a mental speed test (how quickly a subject can process information…
- Trial name
- NCT02600572
- Testing
- Isometric exercises, Eccentric exercises
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Carrick Institute for Graduate Studies
Temperature Change, Body
Remote Biomonitoring (RBM) for Temperature Surveillance of Mothers and Newborns: Pre-clinical and Clinical Evaluation
Based on client needs and technological requirements, a wearable sensor device was designed and developed using principles of 'social innovation' design.
- Trial name
- NCT04608565
- Testing
- Remote biomonitoring sensor device
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- St. John's Research Institute
Adolescent Behavior
Changes in Sagittal Spine Posture and Flexibility on Adolescents
Several research show a high prevalence of spinal misalignments and a lack of stability of the spine in the adolescent population.
- Trial name
- NCT03831867
- Testing
- Pilates
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Posttraumatic Stress Disorder
Attention Bias Modification Treatment for Warzone-Related Posttraumatic Stress Disorder (PTSD)
Veterans with Posttraumatic Stress Disorder (PTSD) will be randomly assigned to either Attention Bias Modification Treatment (ABMT) designed to reduce bias toward threat or a placebo control condition not designed to change…
- Trial name
- NCT01564667
- Testing
- Attention Bias Modification Training Protocol
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Creighton University
Pregnancy, Retinal Nerve Fiber Layer Thickness
Retinal Nerve Fiber Layer and Macular Thickness Changes During Pregnancy
Purpose: Primary: to prospectively measure Retinal Nerve Fiber Layer (RNFL) and macular thickness changes during pregnancy by Optical coherence tomography Secondary: The effect of pregnancy abnormalities on RNFL and macular…
- Conditions
- Pregnancy, Retinal Nerve Fiber Layer Thickness, Macular Thickness
- Trial name
- NCT02154945
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Anesthesia
Modified Paramedian Versus Conventional Technique in the Residency Training: An Observational Study
Residency training includes positive and negative aspects. Well-trained doctors must be educated, but the process may bring additional risks to patients.
- Trial name
- NCT03389672
- Testing
- spinal anesthesia, epidural anesthesia, combined spinal-epidural anesthesia
- Volunteers
- 518 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Aging Well, Walking, Difficulty
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
To test the hypothesis that home-based leg heat therapy improves functional capacity, vascular function, and exercise hyperemia in older adults.
- Conditions
- Aging Well, Walking, Difficulty, Hyperemia
- Trial name
- NCT05706181
- Testing
- Home-based leg heat therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Cognitive Change
Effectiveness of Cognitive Training in Older and Younger Adults
The proposed study will enroll 1600 participants to examine the effectiveness of cognitive training. Participants will be randomized into different experimental groups and can expect to participate for up to 15 hours of research…
- Trial name
- NCT06375681
- Testing
- Visual and / or Auditory Cognitive Tasks (1), Visual and / or Auditory Cognitive Tasks (2)
- Where
- 3 sites in United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Obstetric Anesthesia, Cardiac Monitoring
Cardiac Output Changes With Uterine Displacement
There is currently little information regarding the hemodynamic differences in uterine displacement techniques. Previous studies examining the hemodynamic effects of uterine displacement maneuvers have focused on incidence of…
- Trial name
- LUDCO (NCT02283931)
- Testing
- TTE / NICOM
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Tuberculosis
A Phase I Study of the Safety and Immunogenicity of MVA85A in Healthy Gambian Volunteers
A Phase I study of the Safety and immunogenicity of MVA85A in healthy Gambian volunteers
- Trial name
- NCT00423839
- Testing
- MVA85A (Tuberculosis vaccine)
- Where
- The Gambia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Oxford
PreDiabetes
Small Steps for Big Changes - Healthy Cities Implementation Science
Small Steps for Big Changes (SSBC) is a diet and exercise counselling program that significantly reduces the risk of developing Type 2 Diabetes (T2D).
- Trial name
- HCIS (NCT06440395)
- Testing
- Behavioural: Small Steps for Big Changes Diabetes Prevention Program
- Where
- 12 sites in Canada
- Volunteers
- 4,400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Rheumatoid Arthritis (RA) and Osteoarthritis (OA)
Serum IL-17 Correlated With Inflammatory Changes in Osteoarthritis and Rheumatoid Arthritis
The total number of the included subjects was 120 in 3 equal groups (RA, OA and control). All subject was subjected to serum IL17 level measurement.
- Trial name
- NCT04474912
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Behavior Change Interventions, Work Environment Adverse Effects
From Yearly Checks to Daily Progress: Evaluating Goal Attainment Scaling (GAS) in Systematic Work Environment Management (SAM) Within the Municipal Sector
The goal of this project is to evaluate a practical method for improving systematic work environment management (SAM) by focusing on health-promoting factors rather than identifying risk-factors, and deficiencies.
- Conditions
- Behavior Change Interventions, Work Environment Adverse Effects, Health Factors, Goal Attainment Scaling
- Trial name
- GAS for SAM (NCT06893471)
- Testing
- GAS for SAM
- Where
- Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
PCOS, Diet Modification
Low Starch Dietary Education Program vs. Traditional Treatment for PCOS
Compare weight loss and metabolic parameters in patients using a low starch dietary education program vs. traditional treatment (i.e., prescribing metformin, low calorie diet and exercise) for health improvement in women with…
- Conditions
- PCOS, Diet Modification, Metabolism, Nutrition Disorders
- Trial name
- NCT03916263
- Testing
- Metformin, One-On-One Dietary Instruction, Video Dietary Instruction
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
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