Clinical trials: Modification
GERD, Obesity
Impact of Weight Loss on Gastroesophageal Reflux Disease in Overweight and Obese Subjects: a Prospective Study
By affecting the gastroesophageal pressure gradient, obesity predisposes to reflux of gastric contents. The investigators hypothesized that the loss of weight will decrease this gradient and as a result decrease the severity and…
- Trial name
- NCT01574573
- Testing
- Self support, group sessions
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Midwest Biomedical Research
Infertility, Female
Progesterone Levels During Ovulation and Luteal Phase
Natural cycles are evaluated during fertility treatments for different therapeutic options, like insemination (IUI), time intercourse (TI) or frozen-thawed embryo transfers (FET).
- Trial name
- NCT05076981
- Testing
- human chorionic gonadotropin
- Where
- United Arab Emirates
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Obesity, Diabetes
Effect of Pomegranate Extract Intake on Body Composition and Blood Pressure.
Pomegranate has gained widespread popularity since the health effects of the whole fruit, as well as its juices and extracts, have been studied in relation to a variety of chronic conditions such as hypertension, diabetes…
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- NCT02017132
- Testing
- Pomegranate extract
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Self-Assessment, Self-Perception
E4D Compare Adapted to Preclinical Endodontics
Based on pilot study's promising results, we decided to further investigate the impact of adapting Planmeca Romexis Compare software to evaluate pulpal access preparations on second-year dental students' technical performance…
- Trial name
- NCT06567236
- Testing
- 3D software
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Medication Adherence
A BCT Intervention for Medication Adherence Among Individuals on Statins
The purpose of this project is to identify the minimum effective dose (MED) of a multi-component behavioral change intervention required to increase levels of medication adherence among participants on primary prevention statin…
- Trial name
- NCT05273736
- Testing
- 5 Behavioral Change Techniques
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Obesity
Preventing Excessive Gestational Weight Gain in Obese Women
The purpose of this study is to study the effects of a multicomponent lifestyle intervention that includes partial meal replacements as a means to prevent excessive gestational weight gain in obese women.
- Trial name
- NCT01545934
- Testing
- Lifestyle intervention
- Where
- 2 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Menopause
Menopausal Sleep Fragmentation and Body Fat Gain
This study aims to investigate the impact of menopause-related sleep fragmentation on metabolic biomarkers of body fat gain. The investigators hypothesize that experimental sleep fragmentation will result in an adverse leptin…
- Trial name
- NCT03047330
- Testing
- Estradiol withdrawal, Fragmented sleep
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Dental Caries, Dental Plaque
Orthodontic Varnish Microbiology Study
Orthodontic treatment is common in teenagers, which typically involve the attachment of metal brackets to the teeth. These brackets often impede proper oral hygiene, leading to plaque accumulation and the development of white…
- Conditions
- Dental Caries, Dental Plaque, Dental White Spot
- Trial name
- NCT04528134
- Testing
- Extended Contact RMGI (Resin-modified Glass Ionomer) Varnish, 5% Sodium Fluoride Varnish
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gestational Weight Gain, Postpartum Weight Retention
eMOMS of Rochester
The project aims to develop, implement and evaluate electronically-mediated behavioral intervention programs for pregnant and postpartum women in order to prevent excessive weight gain during pregnancy and postpartum weight…
- Trial name
- eMOMS (NCT01331564)
- Testing
- electronic intervention during pregnancy and postpartum, electronic intervention during pregnancy, Control
- Where
- United States
- Volunteers
- 1,641 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Healthcare Professionals, Sustainability
Climate Change Awareness: a Randomized Controlled Trial
Background: Climate change awareness among nurse managers is crucial for enhancing healthcare efficiency and mitigating environmental and societal impacts.
- Conditions
- Healthcare Professionals, Sustainability, Climate Change
- Trial name
- NCT06905548
- Testing
- climate change awareness training
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Obesity and Type 2 Diabetes, Diet Modification
Mobile Regulation of Craving Training (mROC-T) to Improve Dietary Intake in Rural Adolescent Girls
The goal of this clinical trial is to test if a regulation of craving training intervention in the form of a mobile phone app can increase fruit and vegetable intake in adolescent girls ages 14-18 years of age.
- Trial name
- ROC Teens! (NCT06723028)
- Testing
- Regulation of craving training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Sacroiliac Dysfunction
Sacroiliac Joint Dysfunction Consequences and Its Reversal by Manipulation
Sacroiliac joint dysfunction (ASI) is an alteration in the normal biomechanics of the joint, which leads to hypomobility or hypermobility of that joint.
- Trial name
- LOUIS (NCT06710535)
- Testing
- Manual Manipulation
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Breast Neoplasm Female
mHealth Behavioural Intervention to Increase Breast Cancer Screening Rates Among Members of the Public
Late-stage presentation of breast cancer cases are on the rise in Malaysia. Encouraging breast screening practices can assist in early breast cancer detection.
- Trial name
- mBLISS-B (NCT06293508)
- Testing
- Standard Health Communication Intervention, Behavioural Change Health Communication Intervention
- Where
- Malaysia
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- Clinical Research Centre, Malaysia
Obesity, Extreme Obesity
Course of Obesity and Extreme Obesity in Adolescents
The rate of adolescent extreme obesity is rapidly rising, and impacting quality of life, psychosocial situation, and health of the affected youth.
- Trial name
- YES (NCT01662271)
- Where
- 5 sites in Germany
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Martin Wabitsch
Diabetes, Heart Diseases
Personalized Responses to Dietary Composition Trial 3
The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT04735835
- Testing
- Dietary Intervention
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Caries, Cervical
Evaluation of Low-shrinkage Giomer Versus Resin-Modified Glass Ionomer in Cervical Caries Lesions: A Clinical Trial
Management of cervical lesions presents serious problems with any restorative material. The two most common reasons for restoration failure are secondary caries at the tooth-restoration interface and loss of retention.
- Trial name
- NCT05930548
- Testing
- Low Shrinkage Giomer
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
LLIN, PBO LLIN, IRS, Larviciding
Adaptive Interventions for Optimizing Malaria Control: a Cluster-Randomized SMART Trial
In the past decade, massive scale-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) have led to significant reductions in malaria mortality and morbidity.
- Trial name
- NCT04182126
- Testing
- Regular long-lasting insecticidal nets, LLIN plus Piperonyl butoxide-treated LLIN, Long-lasting microbial larvicide
- Where
- 2 sites in United States, Kenya
- Volunteers
- 122,872 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Benign Paroxysmal Positional Vertigo
Paroxysmal Positional Vertigo & Repositioning Maneuvers
: Benign Paroxysmal Positional Vertigo is a condition related to vestibular system accompanied by dizziness, tinnitus and balance problems leading to increased fall risk and potential disability.
- Trial name
- NCT05309538
- Testing
- Modified eply & Semont maneuver, betahistine & Modified eply & Semont maneuver
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Muscle Atrophy
Brain and Muscle Plasticity During Immobilization
Patients in rehabilitation may undergo periods of prolonged limb immobilization in response to injury, surgery, or illness. Due to disuse, the size and strength of muscles controlling the affected limb can decrease significantly…
- Trial name
- NCT05115643
- Testing
- Immobilization
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- McGill University
Smoking Cessation
Helping Moms Who Smoke
The purpose of this study is to learn how women's smoking changes during their pregnancy and as a new mom, and to assess the help they receive from their health care providers.
- Trial name
- NCT03104452
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
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