Clinical trials: Movement Abnormalities
Accidental Fall, Postural Balance
The Relation Between Movement Patterns, Balance Performance, Function of the Inner Ear and Falls
Falls are one of the most common reasons for immobilisation and death in elderly population. This study aims at studying falls among a group of older people.
- Conditions
- Accidental Fall, Postural Balance, Movement Disorders in Old Age
- Trial name
- NCT03503916
- Where
- Sweden
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Lund University
Neonatal Disease, Parenting
Neonatal Neurobehavioral And Motor Behavior In Ultra Early Physical Therapy Intervention
Investigation of the combination of neonatal neurobehaviourism and motor behavior in the assessment and ultra-early physical therapy intervention of premature neonates and parental support.
- Conditions
- Neonatal Disease, Parenting, Premature Birth
- Trial name
- NCT05565287
- Testing
- ultra early physiotherapy intervention
- Where
- 3 sites in Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Parkinson Disease
Neural Control of Breathing in Parkinson's Disease
Breathing is a complex process, which can be controlled through voluntary command or neural control. Parkinson's disease (PD) is a progressive neurological disorder.
- Trial name
- NEURON-PD (NCT06074614)
- Testing
- Hypercapnic ventilatory response, Respiratory related evoked potential, Transcranial magnetic stimulation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Parkinson Disease
Virtual-reality for Upper Limb Rehabilitation in People With Parkinson's Disease
The aim of this study is to assess the effect of 8-week physiotherapy training using immersive virtual reality (VR-training) compared to a physiotherapy training performed in a real setting (RS-training) on handwriting and touch…
- Trial name
- NCT04876352
- Testing
- Upper limb/handwriting exercises in an immersive virtual reality setting (VR-training), Upper limb/handwriting exercises in a real setting (RS-training), No intervention
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Prof. Massimo Filippi
Parkinson Disease, LRRK2
LRRK2, GBA and Other Genetic Biomarkers in Eastern European (Ashkenazi) Jews With and Without Parkinson's Disease
Single site observational study focused on elucidating the genes and biochemical pathways involved in causing Parkinson disease.
- Conditions
- Parkinson Disease, LRRK2, GBA Gene Mutation
- Trial name
- BioPD (NCT04668898)
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Wilson Disease, D-Penicillamine
Wilson's Disease Treated With D-Penicillamine: Characterization of Skin Damage Secondary to Treatment by Measuring Skin Elasticity
Wilson's disease is a genetic disorder, resulting from an anomaly present on the ATP7B gene located on chromosome 13, causing a progressive accumulation of copper in various organs such as the liver, nervous system and cornea…
- Conditions
- Wilson Disease, D-Penicillamine, Effect of D-penicilline on Cutaneous Elastity of Wilson's Patient
- Trial name
- WILDERME (NCT06945081)
- Testing
- Preparation of forearm molds with SILFLO® silicone
- Where
- 2 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Parkinson's Disease, Multiple System Atrophy
PET Imaging Evaluation of [11C]SY08
The overall goal of the proposed research is to evaluate the use of [11C]SY08 as a PET radiotracer for aggregated alpha synuclein (αS) in individuals with Parkinson's disease (PD), Multiple system atrophy (MSA), Dementia with…
- Conditions
- Parkinson's Disease, Multiple System Atrophy, Dementia With Lewy Bodies, Healthy Controls
- Trial name
- NCT06098612
- Testing
- C11-SY08
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism, Autism Spectrum Disorder
Comparing Imitation and Stereotyped Behaviors in Autistic Children: Robots vs. Human Operators
Virtual QT is a social robot designed to interact with humans in social and educational contexts. Equipped with visual and vocal interfaces, the robot can recognize and respond to various human inputs, providing emotional support…
- Trial name
- NCT06144528
- Testing
- QT robot
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Movement Disorders (Incl Parkinsonism), Tremor Familial Essential, 1
MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder.
This proposal is focused on developing a reliable, valid, and reproducible imaging techniques and statistical methodology for segregation of various forms of Parkinsonism from healthy adults without Parkinsonism.
- Conditions
- Movement Disorders (Incl Parkinsonism), Tremor Familial Essential, 1, REM Sleep Behavior Disorder
- Trial name
- NCT01547481
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Movement Disorders, Muscle Tone
Massage and Cold Water Immersion on Movement Variability After Fatigue in Swimmers
The goal of this clinical trial is to investigate the effectiveness of post-exercise massage and cold-water immersion compared to control in young elite swimmers.
- Conditions
- Movement Disorders, Muscle Tone, Perceived Exertion
- Trial name
- NCT04541901
- Testing
- Massage, Cold water immersion
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Flávia Carvalho
Parkinson Disease
Synaptic Density and Progression of Parkinson's Disease.
AIM: To assess synaptic density and to investigate the potential relationship of regional synaptic loss with motor and non-motor symptoms and with disease progression in the human brain in vivo in patients with PD.
- Trial name
- NCT04243304
- Testing
- 11C-UCB-J PET-CT, 18F-PE2I PET-MR
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Parkinson Disease (PD), Paralysis; Supranuclear
Progression of Striatal and Extrastriatal Degeneration in PD and PSP Patients
This longitudinal study aims to research cognitive and gait phenotypes of Parkinson's disease and Supranuclear Palsy as well as to provide markers to track diseases progression using a multi-modality approach based on 3D-gait…
- Trial name
- PARKONTHEWAY (NCT03840252)
- Testing
- 3D gait analysis, rsfMRI, Montreal Cognitive assesment (MoCA)
- Where
- Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Functional Movement Disorders, Reproducibility of Results
Aspects of Validity of the Single Leg Squat Test: A Cohort Study of Female Soccer Players.
Movement screening tests to identify deficits or poor movement quality is commonly used in soccer and other sports to assess injury, to evaluate rehabilitation goals and return to sport after injury.
- Conditions
- Functional Movement Disorders, Reproducibility of Results, Sports Medicine
- Trial name
- NCT05289284
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Parkinson Disease
Study of Motor Inhibition in Parkinson's Disease and Focal Hand Dystonia
The current research protocol aims at studying preparatory inhibition in two populations of patients suffering from movement disorders.
- Trial name
- PD-INHIB (NCT05209516)
- Testing
- Behavioral data, Single-pulse transcranial magnetic stimulation (TMS), Questionnaires
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders
Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resilience and Neurodegeneration in Neurological Diseases and Healthy Aging
The MESO7 study is a prospective observational research project designed to investigate the mechanisms of resilience and neurodegeneration in neurological diseases and healthy aging.
- Conditions
- Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD), Alzheimer Disease
- Trial name
- MESO7 (NCT07202494)
- Testing
- Imaging Techniques (MRI 3T & 7T, Functional, Structural, and Metabolic Imaging)
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Postural Kyphosis, Postural Lordosis
Investigating Association Between Spine, Scapular, Shoulder and Core in Swimmers
The aim of this observational study is to investigate relationship between cervical, thoracic, lumbar and thoracolumbar spine posture, spine movement, isometric and eccentric shoulder strength, scapular dyskinesis and core muscle…
- Conditions
- Postural Kyphosis, Postural Lordosis, Movement, Abnormal, Spine Injury
- Trial name
- NCT06326177
- Testing
- Spine Posture Assessment, Spine Movement Assessment, Core Muscle Endurance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Brain Diseases, Central Nervous System Diseases
Digital Diagnostics and Intervention Services for Parkinson's Disease
People with Parkinson's have infrequent clinical consultation (once every 12-18 months) and limited rehabilitation. Assessment play an important role in these consultations to help clinicians understand patients' health status…
- Conditions
- Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Joint Diseases
- Trial name
- NCT06534177
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Parkinson's Disease (PD)
Untreated Parkinson's Disease Work-up Assessing Resident Microbiota and Duodenal Barrier Function
The UPWARD study is a prospective hypothesis-generating study in individuals with untreated Parkinson's disease (PD) and age-matched healthy controls (HCs).
- Trial name
- UPWARD (NCT07418658)
- Testing
- Invasive sampling procedures, Non-invasive sampling procedures
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Parkinson Disease
EEG Recordings and Analysis in Parkinson's Patients: Towards Adaptive Deep Brain Stimulation by Machine Learning
The objective of this protocol is to obtain on Parkinson's disease more accessible therapeutic targets than deep brain stimulation (HFS-STN), the neurosurgical treatment for this pathology.
- Trial name
- ElectroPARK (NCT05284526)
- Testing
- electroencephalogram (EEG) of control and parkinsonian subjects during the preparation and execution of movements
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinson Disease
Study of Sexuality in Parkinson Disease
The aim of this study is to evaluate the different aspects of sexual function among adults with Parkinson Disease to develop a treatment and address sexual problems as a routine part of diagnostic workup and therapeutic planning.
- Trial name
- Sex-PD (NCT01878409)
- Where
- Italy
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
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