Clinical trials: Muscle Disorders
Polymyalgia Rheumatica, Rheumatoid Arthritis
Protocol For The Quantitation Of Pain In The Diagnosis Of Polymyalgia Rheumatica
The aim of this study is to evaluate a simple and rapid method in order to better define and treat Polymyalgia Rheumatica by measuring levels of muscle achiness and pain with a blood pressure cuff.
- Conditions
- Polymyalgia Rheumatica, Rheumatoid Arthritis, Rheumatic Disease
- Trial name
- NCT00847236
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Lahey Clinic
Epicondylitis, Lateral
Epicondylar Muscle Activation in Tennis Players
Epicondylitis is one of the most common pathologies in tennis players. The search for an effective treatment is necessary for the relief of symptoms and the return to sports practice.
- Trial name
- NCT06160011
- Testing
- Electrical dry needling + Conventional physiotherapy, Dry needling + Conventional physiotherapy, Conventional physiotherapy
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Obesity, Skeletal Muscle
Anti-Inflammatory Milk Matrix
Obesity is pro-inflammatory, impairs metabolism, and physically limiting. Specifically, muscle in obese persons does not synthesize proteins normally. This further increases metabolic and physical dysfunction.
- Conditions
- Obesity, Skeletal Muscle, Inflammation
- Trial name
- AIMM (NCT04216004)
- Testing
- Controlled-Feeding Intervention, Non-dairy beverage, Full-fat milk
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Sleep Apnea, Obstructive
Effect of Dalfampridine (4-AP) on Genioglossus Muscle Activity in Healthy Adults
In this protocol the investigators will test the effect of dalfampridine (a potassium channel blocker) on genioglossus muscle activity (EMG GG) during wakefulness and sleep in healthy control subjects.
- Trial name
- APIGLOSS (NCT02656160)
- Testing
- Dalfampridine
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hip Joint, Muscle Weakness
The Effect High Velocity Low Amplitude Hip Mobilization on Strength in Subjects With Lower Extremity Pathology
Introduction: Lower extremity weakness associated with musculoskeletal pathology can cause activity limitations. Physical therapy intervention in the form of exercise is commonly directed at improving muscular performance…
- Trial name
- NCT03115879
- Testing
- Hip mobilization, Hip manipulation simulation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Sarcopenia, Chronic Lung Disease
Feasibility of Proteomics in Chronic Lung Disease With Sarcopenia
Sarcopenia, the loss of muscle mass and strength with ageing, is a prevalent condition in older adults, particularly those with chronic lung diseases like COPD and interstitial lung disease.
- Trial name
- NCT06312774
- Testing
- This is observational study
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University College, London
Obesity, Type 2 Diabetes
Changes of Biomarkers in Response to Training and Antioxidant Treatment
The aim of the study is to compare the effects of an intensive 4 weeks exercise training program with or without additional treatment with antioxidants.
- Trial name
- NCT00638560
- Testing
- Vitamin C, Vitamin E, Antioxidant treatment
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Myofascial Pain Syndrome
Ultrasonographic Muscles and Fascia Measurement With Myofascial Pain Syndrome
Pathologies in the trapezius muscle and rhomboid muscle are important in the course and treatment of the disease in patients with myofascial pain syndrome.
- Trial name
- NCT05359523
- Testing
- Ultrasonographic measurements of the trapezius and rhomboid muscle and fascia, fascia injection
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Healthy
Capsaicin-induced Muscle Pain in Humans
There is currently no specific diagnostic test for primary muscular pain. The present study investigates whether selective blockade of the suprascapular nerve can effectively abolish experimental pain arising from the…
- Trial name
- NCT02377180
- Testing
- Intramuscular capsaicin injection, Suprascapular nerve block, Local anesthetic infiltration
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lax Skin
Treatment for Lifting Upper Arm Lax Skin
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT05358327
- Testing
- Sofwave
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Symptomatic Lumbar Spinal Stenosis, Lumbar Spinal Stenosis
Muscle Function and Pelvic Stability While Walking in Patients With Symptomatic Lumbar Spinal Stenosis
This study is to quantify changes in muscle activity and pelvic stability during prolonged walking in patients with symptomatic lumbar spinal stenosis (sLSS) and healthy control subjects and to determine their association with…
- Trial name
- WALK-LSS (NCT03951935)
- Testing
- Oswestry Disability Index (ODI) questionnaire, self-paced walking test (SPWT)
- Where
- Switzerland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Signs and Symptoms, Fever
Biomedical Signal Extraction From Symptom Descriptions: An Observational Registry Using the OpenGenome Platform
This registry prospectively collects anonymized free-text symptom descriptions submitted voluntarily by adults through the OpenGenome platform at opengenome.bio.
- Conditions
- Signs and Symptoms, Fever, Myalgia, Skin Diseases
- Trial name
- OGNOME-REG (NCT07578610)
- Testing
- OpenGenome AI Platform
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- OpenGenome
Metabolic Dysfunction-associated Steatotic Liver Disease
Targeting the Skeletal Muscle to Treat Metabolic Dysfunction-associated Steatotic Liver Disease
Muscle changes including myosteatosis are reported as highly prevalent in metabolic dysfunction-associated steatotic liver disease (MASLD). Recent studies highlighted a link between muscle fat content and liver disease severity.
- Trial name
- MYO-MASLD (NCT06506513)
- Testing
- High-intensity interval training, Moderate intensity exercise training, Low intensity exercise training
- Where
- 2 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Multiple Sclerosis
Effects of Torso Weighting on Muscle Activation During Balance Tests in Individuals With and Without Multiple Sclerosis
Rationale: The Balance-Based Torso-Weighting (BBTW) is a patented evaluation system that uses strategic placement of small or lightweight weights on the trunk to improve balance and stability.
- Trial name
- BBTW-MS (NCT06981013)
- Testing
- balance based torso weighting
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of St. Augustine for Health Sciences
Heart Failure
Oral Nitrite for Older Heart Failure Patients
Studies have demonstrated nitrite therapy increases adenosine triphosphate (ATP) synthesis in skeletal muscle mitochondria concomitant with reduced whole-body oxygen cost during steady state exercise.
- Trial name
- ONTx+HF (NCT02457260)
- Testing
- 14 N Sodium Nitrite
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Gladwin, Mark, MD
Fibromyalgia
Study of Fibromyalgia Treated With Milnacipran
The purpose of this study is to examine the characteristics of the nerves and the small veins in the skin of people with fibromyalgia.
- Trial name
- NCT01125423
- Testing
- Milnacipran, Skin biopsy
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Temporomandibular Joint Disorders
Evaluation of the Effect of Dextrose Prolotherapy Versus Dry Needling Therapy
The hypertonic dextrose injection; Prolotherapy is a proliferation injection therapy that aims to trigger a low-grade inflammatory response inside the (TMJ), with the resultant captivation of abundant fibroblasts that regenerate…
- Trial name
- NCT05821985
- Testing
- The study group, The Control group
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Aging, Sarcopenia
Krill Oil and Muscle in Older Adults
The aim of this study is to determine the effects of krill oil supplementation on muscle mass in function in older adults. Half of the participants will receive krill oil supplements and the other half a placebo.
- Trial name
- NCT04048096
- Testing
- Krill Oil
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Muscle Soreness
Effect of Acheta Domesticus Supplementation on Post-Exercise Muscle Recovery in Recreationally Active Male
The goal of this clinical trial is to test the effect of house cricket (Acheta domesticus) supplementation for strength recovery in recreationally active males.
- Trial name
- NCT06096389
- Testing
- 100 Drop Jumps, Whey supplementation, Carbohydrate supplementation
- Where
- Malaysia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Asymptomatic Condition
Muscle Energy Techniques and Trigger Point Therapy in Asymptomatic Persons With Latent Trigger Point
The main objective of this study is to evaluate the effectiveness of therapy which will be a combination of Muscle Energy Technique (MET) and Trigger Point Therapy (TPT), performed bilaterally on the upper trapezius muscle in the…
- Trial name
- NCT04360668
- Testing
- Muscle Energy Technique (MET), Trigger Point Therapy (TPT), Muscle Energy Technique (MET) combined with Trigger Point Therapy (TPT)
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education