Clinical trials: Muscular Hypertrophy
Muscle Hypertrophy, Muscle Strength
Upper Versus Lower Limb Responses to Higher Versus Lower Load Resistance Training in Young Men
Recent research suggests that performing resistance exercise training with relatively light loads is equally as effective at increasing muscle mass and muscle strength as performing resistance exercise training with relatively…
- Trial name
- NCT03993483
- Testing
- Unilateral resistance exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Menstrual Cycle, Resistance Exercise
Menstrual Cycle Phase Based Training
The primary purpose of this study is to employ state-of-the-art methods to fill current knowledge gaps on the effects of the menstrual cycle on resistance exercise training adaptations.
- Trial name
- MCPBT (NCT05936424)
- Testing
- Unilateral Resistance Exercise Leg, Non-Exercise Control Leg
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McMaster University
Type 2 Diabetes
RESIST! Blood-flow Restriction Resistance Training for Improving Insulin Sensitivity in Type 2 Diabetes
The study aims to investigate the metabolic and cardiovascular effects of classical resistance training with high loads and blood-flow restricted training (BFRT) with low loads in individuals with type 2 diabetes over 12 weeks.
- Trial name
- RESIST (NCT04222231)
- Testing
- Blood-flow restriction resistance training, Classical resistance training
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Muscle Hypertrophy
The Load-velocity Relationship: Neuromuscular Adaptations to Resistance Training
Adaptations to resistance training are highly specific and depend on the combination of external loading and the level of individual adaptability.
- Trial name
- NCT06760663
- Testing
- The load-velocity relationship: Neuromuscular adaptations to resistance training
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Sarcopenia in Elderly, Muscle Atrophy
Effects of Cyclical Blood Flow Restriction Exercise on Muscle Hypertrophy and Capillaries in Older Adults
The purpose of this study was to learn if low-load resistance exercise combined with cyclical blood flow restriction (BFR) could improve small blood vessel structure and muscle size in older adults.
- Conditions
- Sarcopenia in Elderly, Muscle Atrophy, Aging
- Trial name
- NCT07689487
- Testing
- Blood Flow Restriction (BFR), Conventional Low-Load Resistance Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Skeletal Muscle Hypertrophy
Effects of a Multi-ingredient Supplement Study: a Randomized Controlled Trial in Men and Women
Resistance exercise training is a known stimulant for muscle protein synthesis (MPS) to occur, however the consumption of protein is also necessary to induce a shift towards a positive net protein balance.
- Trial name
- SRCT (NCT03525197)
- Testing
- Whey protein-based supplement, Collagen protein-based supplement
- Where
- 2 sites in Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- McMaster University
Athletic Performance, Muscle Strength
Comparison of Velocity-Based and Traditional Strength Training in Youth Soccer Players
This study compared the effects of velocity-based strength training and traditional strength training on physical performance and muscle adaptations in youth soccer players.
- Conditions
- Athletic Performance, Muscle Strength, Resistance Training
- Trial name
- NCT07447258
- Testing
- Velocity-Based Training (10% Velocity Loss), Velocity-Based Training (20% Velocity Loss), Traditional Strength Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Engin Güneş Atabaş
Hypertrophy, Body Weight Changes
Examining Changes in Muscle Size and Body Composition Between Two Hypertrophy Resistance Training Programs in Males
This study aims to investigate if a less physically and psychologically taxing approach to resistance training can generate equal or greater outcomes when compared to a more physically and psychologically taxing approach.
- Conditions
- Hypertrophy, Body Weight Changes, Muscle Size
- Trial name
- NCT05667233
- Testing
- Resistance Training Program
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Dalhousie University
Healthy Volunteers, Muscle Hypertrophy
Glycolytic Phenotype (vLapeak) and Magnitude of Skeletal Muscle Hypertrophy After Resistance Training
The HyperLa study investigates whether a person's "glycolyticness"-the efficiency with which their body uses glycolysis for energy-can predict how much their muscles will grow (hypertrophy) in response to resistance training.
- Conditions
- Healthy Volunteers, Muscle Hypertrophy, Glycolysis, Moderately Trainend
- Trial name
- HyperLa (NCT07721766)
- Testing
- Hypertrophy-focused Resistance Training
- Where
- 8 sites in Finland, Germany and 2 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Muscle Hypertrophy, Bone Mineral Density Loss
Combined Whey Protein and Collagen Supplementation in Resistance-Trained Men
This study tested whether taking whey protein together with collagen peptides would provide greater benefits for muscle and bone health compared to whey protein alone, collagen alone, or a placebo.
- Conditions
- Muscle Hypertrophy, Bone Mineral Density Loss, Resistance Training Adaptation
- Trial name
- NCT07171411
- Testing
- Whey Protein + Collagen, Whey Protein, Collagen Peptides
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Muscle Hypertrophy, Muscular Strength
Determining the Effect of Shoulder Flexion Angle on Latissimus Dorsi and Forearm Flexor Hypertrophy
The goal of this clinical trial is to learn the effect of training a muscle at a longer or shorter muscle length during resistance exercise in young and healthy adults.
- Trial name
- LPDLR (NCT07360236)
- Testing
- LAT PULLDOWN and LAT ROW training sessions, Maximal isotonic strength testing (1RM), Isokinetic strength testing (1080 Quantum)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Muscle Atrophy, Disuse Atrophy (Muscle) of Lower Leg
The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation
It is well known that periods of weight training lead to increases in skeletal muscle size and strength. In contrast, periods of inactivity such as bed rest or immobilization result in losses of skeletal muscle size and strength.
- Trial name
- HYPAT (NCT03046095)
- Testing
- Unilateral Resistance Exercise, Immobilization
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- McMaster University
Skeletal Muscle Hypertrophy, Muscle Weakness
The Effects of Lifting Light or Heavy Weights on Muscle Growth and Strength in Trained Young Men
When practicing weightlifting regularly the body makes new proteins within the muscle. These new proteins can increase the size of the cells within the muscle to make them larger, a process called hypertrophy.
- Trial name
- NCT02139865
- Testing
- 30% 1RM, 80% 1RM
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Healthy, Skeletal Muscle Atrophy
Evaluating Changes in Skeletal Muscle Proteins Following Resistance Exercise and Single-Leg Disuse
Skeletal muscle plays a critical role in supporting human health. Beyond its role in providing the force to move, skeletal muscle accounts for a large proportion of metabolic rate, glucose disposal, and amino acid storage.
- Conditions
- Healthy, Skeletal Muscle Atrophy, Skeletal Muscle Hypertrophy
- Trial name
- NCT06350591
- Testing
- Immobilization, Resistance training
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Queen's University
Healthy
The Effects of Lower Extremity Blood Flow Restriction Training on Power, and Muscle Size.
Blood-flow restriction training (BFR) is a technique utilized to provide the benefits of high intensity exercise (strength, power, hypertrophy) when applied to exercise intensities that are insufficient to produce these benefits…
- Trial name
- NCT03983070
- Testing
- Seated Rowing Ergometer, Deadlift, Blood flow restriction
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Campbell University, Incorporated
Muscle Hypertrophy in Healthy Young Men
Chronic Beta2-adrenergic Stimulation and Cardiac and Skeletal Muscle Hypertrophy
Studies in animals have shown that beta2-adrenoceptor activation with selective agonists regulates protein metabolism and muscle growth in skeletal and cardiac muscle tissue.
- Trial name
- NCT02551276
- Testing
- Salbutamol, Resistance training
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Strength Training Adaptations
Effects of Traditional and Cluster Set Resistance Training on Muscle Strength, Hypertrophy, and Power
This study aims to compare the effects of traditional resistance training and two different cluster set configurations on muscle strength, muscle hypertrophy, and explosive performance.
- Trial name
- NCT07910188
- Testing
- Traditional Set Resistance Training, Three-Repetition Cluster Set Training, Six-Repetition Cluster Set Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GÜRKAN DİKER
Hypertrophy
Egg Consumption and Muscular Adaptations
Eggs may be a viable alternative to various types of supplemental proteins given its similar ratings on various measures of dietary protein quality.
- Trial name
- NCT04381390
- Testing
- Whole egg and resistance training, Egg whites and resistance training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexei Wong
Muscle Hypertrophy in Healthy Young Men
Effects of Deloading Periods in Resistance Training on Muscular Strength and Hypertrophy
This study investigates the effects of deloading periods (short breaks or reductions in training volume) in a 8-week resistance training program on muscle strength and hypertrophy in young, untrained individuals.
- Trial name
- DPRT (NCT06825052)
- Testing
- Resistance Training with Deloading Periods, Continuous Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Blood Flow Restriction
Eccentric Resistance Training With Blood Flow Restriction on Muscle Function
The study will determine the effects of adding blood flow restriction to eccentric training to assess whether this increases the improvements of muscle strength and size.
- Trial name
- NCT04977804
- Testing
- Exercise, Eccentric plus blood-flow restriction
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Utah State University