Clinical trials: Neglected Diseases
Impostor Phenomenon, Cognitive Complaints
Impostor Phenomenon and Cognitive Complaints in Anesthesiologists
This prospective observational cross-sectional survey study aims to investigate the relationship between impostor phenomenon and cognitive complaints in anesthesiologists, and to evaluate the role of potential confounding factors…
- Conditions
- Impostor Phenomenon, Cognitive Complaints, Burnout, Professional
- Trial name
- NCT07648576
- Testing
- Self-Administered Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Fusun Gozen
Stroke, Hemispatial Neglect
mCIMT and Eye Patching for Neglect Rehabilitation Post Stroke: A Longitudinal Study of Separate and Combined Effects
The purpose of the current study is to evaluate relative efficacy of (1)modified constraint-induced movement therapy (mCIMT) combined with eye patching, (2)mCIMT, and (3) traditional rehabilitation on motor, attentional, and…
- Trial name
- NCT00253825
- Testing
- mCIMT combined with or without eye patching
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Cognition Disorders, Cognitive Deficits
Smart Autonomous Neuro-Rehabilitation System
Cognitive rehabilitation is defined as a systematic functionally oriented intervention of therapeutic cognitive activities based on the assessment and understanding of patient's brain behavior deficits.
- Trial name
- SANaR (NCT02816008)
- Testing
- Cognitive rehabilitation training with RGS in the clinic, Passive/conventional cognitive training at home.
- Volunteers
- 59 people
- Sponsor
- Universitat Pompeu Fabra
Hookworm Infection, Hookworm Disease
Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults
Na-GST-1 and Na-APR-1 are proteins expressed during the adult stage of the Necator americanus hookworm life cycle that are thought to play a role in the parasite's degradation of host hemoglobin for use as an energy source.
- Trial name
- NCT02126462
- Testing
- Na-APR-1 (M74)/Alhydrogel®, Na-GST-1/Alhydrogel®, Hepatitis B vaccine
- Where
- Gabon
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Hypertension, Diabetes Mellitus
Implementation of the COmmunity HEalth System InnovatiON Project in Low- and Middle- Income Countries
The COHESION-I project will evaluate the effects of the co-creation intervention (2016 to 2019) and the co-design intervention (2023 to 2024) on improving (a) health system responsiveness, and (b) patient satisfaction, at the…
- Conditions
- Hypertension, Diabetes Mellitus, Neglected Tropical Diseases
- Trial name
- COHESION-I (NCT06989502)
- Testing
- Co-creation (2016 to 2019) + Co-design (2023 to 2024), Co-design only (2023 to 2024)
- Where
- 3 sites in Mozambique, Nepal and 1 more
- Volunteers
- 2,094 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Stroke
Fluoxetine for Motor, Aphasia, and Neglect Recovery After Ischemic Stroke
This pilot study will recruit 25 subjects to assess the feasibility of replicating the FLAME study (Chollet, et al. Lancet 2011), a randomized controlled trial (RCT) that assessed the effect of fluoxetine vs placebo on motor…
- Trial name
- FLAN (NCT01674868)
- Testing
- fluoxetine
- Where
- United States
- Sponsor
- Spaulding Rehabilitation Hospital
Neglect, Sensory, Neglect, Hemispatial
Mixed-Reality Visual Attention Task for Neglect Diagnosis and Rehabilitation
Neglect, a common and disabling neurological deficit post-CNS injury, profoundly hinders recovery and escalates healthcare costs.
- Conditions
- Neglect, Sensory, Neglect, Hemispatial, Neglect, Hemisensory
- Trial name
- Neglex01 (NCT07227844)
- Testing
- VR Neglect Training
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Markey Olson
Stroke Sequelae, Neglect, Hemispatial
Virtual Reliability System for Visual Spatial Attention Evaluation in Stroke Patients
The researchers designed a software based on a head-mounted displays for virtual reality (HMD-VR) to evaluate the reaction time to stimuli presented at right or left visual field.
- Trial name
- NCT05332964
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke, Spatial Neglect
Development of a Virtual Reality Spatial Retraining Therapy to Improve Neglect in Stroke Survivors
Participants in this study will help test and develop a virtual reality (VR) system that is being designed to help people with spatial neglect after stroke.
- Trial name
- VR-SRT (NCT04793516)
- Testing
- VR Therapy Game
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Stroke
Effects of Repetitive Transcranial Magnetic Stimulation Combined With Sensory Cueing on Unilateral Neglect in Subacute Patients With Right Hemispheric Stroke
The objective was to compare the effects of repetitive Transcranial Magnetic Stimulation (rTMS) combined with sensory cueing (SC), rTMS alone, and conventional rehabilitation on reducing unilateral neglect (UN) and improving…
- Trial name
- NCT02645344
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Sensory Cueing (SC), Conventional Rehabilitation
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Scabies; Itch, Scabies
Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age (ITCHY Study)
This is an open label prospective pharmacokinetic single arm study in Laos PDR. This study will be embedded within a cluster-randomized controlled trial of interventions to address childhood undernutrition (SUANHOAM Trial…
- Trial name
- ITCHY (NCT05500326)
- Testing
- Ivermectin Tablets
- Where
- 5 sites in Laos
- Volunteers
- 120 people
- Sponsor
- Murdoch Childrens Research Institute
Cerebrovascular Disorders, Cerebral Stroke
Using Repetitive Transcranial Magnetic Stimulation (rTMS) in the Rehabilitation of Chronic Spatial Neglect After Stroke
Visuospatial neglect is a common neurological symptom which appears following strokes on regions of the right hemisphere of the brain.
- Conditions
- Cerebrovascular Disorders, Cerebral Stroke, VISIO-spatial Neglect, VISUO-spatial Extinction
- Trial name
- NEGLECT (NCT01000103)
- Testing
- Real rTMS
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Complex Regional Pain Syndromes, Fibromyalgia
Virtual Environment Rehabilitation for Patients With Motor Neglect Trial
Motor neglect describes a loss of function without a loss of strength, reflexes or sensation. Motor neglect has been described in patients with traumatic brain injury, stroke and chronic pain conditions, e.g.
- Conditions
- Complex Regional Pain Syndromes, Fibromyalgia, Stroke, Traumatic Brain Injury
- Trial name
- VERMONT (NCT03887962)
- Testing
- Virtual Environment Biofeedback, Treadmill walking with no Virtual Environment Biofeedback
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Neglect, Hemispatial, Neglect, Sensory
OKS for the Treatment of Hemispatial Neglect
Hemispatial neglect is a disorder where the patient has difficulty attending to objects and information in the left side of space, which occurs following strokes to the right side of the brain.
- Conditions
- Neglect, Hemispatial, Neglect, Sensory, Neglect, Hemisensory
- Trial name
- NCT03451708
- Testing
- OKS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Addiction, Substance Abuse Drug Chronic
Stage III Community-based Efficacy Trial for Mothering From the Inside Out
This is a Stage III community-based randomized clinical efficacy trial testing Mothering from the Inside Out (MIO), the first evidence-based parenting intervention designed to be delivered by addiction counselors in addiction…
- Conditions
- Addiction, Substance Abuse Drug Chronic, Child Neglect, Child Neglect Emotional
- Trial name
- NCT02955199
- Testing
- Mothering From the Inside Out (MIO), Parent Education
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Yale University
Neglect, Child, Non-Accidental Trauma
Supervisory Neglect, Non-Accidental Trauma, Brief Intervention, and Treatment Referral
The Supervisory Neglect, Non-Accidental Trauma, Brief Intervention, and Treatment Referral (SunBrite) protocol is a family-empowered, risk mitigation strategy that targets families with young children who present to the ED with…
- Conditions
- Neglect, Child, Non-Accidental Trauma, Non-Accidental Injury to Child, Head Trauma
- Trial name
- SunBrite (NCT03704272)
- Testing
- SunBrite
- Sponsor
- Phoenix Children's Hospital
Chronic Inflammatory Bowel Disease
Methotrexate-associated Anti-TNF Combination Therapy, the Neglected One !
The results of the SONIC trial represented a significant advance in the management of patients with chronic inflammatory bowel disease by demonstrating the superiority of the combination of an alpha TNF anti-TNF with…
- Trial name
- MTX (NCT04196920)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Normal Physiology, Stroke
Effects of Prism Adaption and rTMS on Brain Connectivity and Visual Representation
Background: After a stroke, the balance between the two halves of the brain can be lost. This may cause people to lose the ability to perceive a side of space. This is called neglect.
- Trial name
- NCT02911129
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Hemispatial Neglect
Effectiveness of Mirror Therapy in Stroke Patients With Unilateral Neglect - A Randomized Controlled Trial
Hemi spatial neglect, or the tendency to ignore stimuli originating in a portion of the environment contra lateral to a cerebral lesion, can be a major source of functional handicap after stroke.
- Trial name
- MUST (NCT01735877)
- Testing
- Mirror therapy, Control group
- Where
- India
- Volunteers
- 48 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Hemispatial Neglect
Rehabilitation Glasses for the Treatment of Hemispatial Neglect
This project is designed to test a lightweight, portable, computerized pair of glasses that will help reduce some of the cognitive deficits seen in patients who have suffered damage to their right cerebral hemisphere.
- Trial name
- NCT02695927
- Testing
- Computer rehabilitation glasses
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Chun Lim