Clinical trials: Nerve Block; Pain Medication
Pain, Total Knee Replacement
Analysis of Postoperative Analgesic of Different Nerve Blocks for Total Knee Replacement Surgery
This study is a retrospective analysis using the accumulated clinical database from 2017/09-2023/12 to analyze patients who underwent total knee arthroplasty and received nerve blocks.
- Conditions
- Pain, Total Knee Replacement, Motor Function
- Trial name
- NCT06521619
- Testing
- Femoral and sciatic nerve blocks
- Where
- Taiwan
- Volunteers
- 126 people
- Sponsor
- Fu Jen Catholic University Hospital
Lumbar Erector Spinae Plane Block, Pericapsular Nerve Group Block (PENG Block)
Combined Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block in Patients Undergoing Hip Surgeries
The investigators are going to evaluate the postoperative analgesic efficacy of combined LESPB and PENG block after hip surgeries.
- Trial name
- NCT05930171
- Testing
- Ultrasound guided L-ESPB and PENG block using Bupivacaine, Postoperative conventional analgesia in form of Acetaminophen
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Breast Cancer, Postoperative Pain
Comparison of Postoperative Analgesic Efficacy of Two Different Blocks in Modified Radical Mastectomy Surgery
Postoperative pain following modified radical mastectomy remains a significant clinical challenge and may delay recovery, impair patient comfort, and increase opioid consumption.
- Trial name
- mastectomy (NCT07737132)
- Testing
- Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Ultrasound-Guided Serratus Anterior Plane Block (SAPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Opioid Use, Postoperative Pain
Comparing Intrathecal Morphine With Modified Thoracoabdominal Nerve Block Through Perichondral Approach in Major Abdominal Surgery
Abdominal surgery causes severe postoperative pain due to retraction of the abdominal wall and direct manipulation of visceral organs. It leads to delayed postoperative recovery, increased postoperative morbidity and mortality.
- Trial name
- NCT06346860
- Testing
- Regional Block Comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Marmara University
PENG Block, Hip Arthroplasty, Total
PENG vs PHPB for Hip Arthroplasty Analgesia
Total hip arthroplasty (THA) is a commonly performed surgical procedure, and its incidence continues to rise with the aging population. Effective postoperative analgesia facilitates early mobilization and accelerates recovery.
- Conditions
- PENG Block, Hip Arthroplasty, Total, QoR-15, Numeric Rating Scale
- Trial name
- NCT07263932
- Testing
- PENG Block and Posterior Hip Pericapsular Block, PENG Block
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Ankara City Hospital Bilkent
Opioid Consumption, Postoperative, Pain, Postoperative
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over…
- Conditions
- Opioid Consumption, Postoperative, Pain, Postoperative, Nerve Block, PENG Block
- Trial name
- NCT06821516
- Testing
- Evaluation of the postoperative analgesic effectiveness of PENG block in participants undergoing total hip arthroplasty under spinal anesthesia, Evaluation of the postoperative analgesic effectiveness of lumbar erector spinae block in participants undergoing total hip arthroplasty under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Shoulder Pain
Dexmedetomidine as an Adjuvant to Bupivacaine in Ultrasound-guided Pericapsular Nerve Group Block( PENG)
Patients are greatly concerned about pain that occurs shortly after shoulder surgeries. Most patients experience significant pain after shoulder surgery, with almost half reporting severe pain immediately after.
- Trial name
- NCT07626346
- Testing
- nerve block
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Postoperative Pain, Acute
Anterior Suprascapular Versus Interscalene Block for Postoperative Analgesia After Arthroscopic Shoulder Surgery in the Outpatient Setting
Shoulder surgery performed in the outpatient setting can be associated with moderate to severe postoperative pain, especially during the first hours after surgery.
- Trial name
- NCT07831096
- Testing
- Interscalene Nerve Block, Anterior suprascapular nerve block, Ropivacaine
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Sette Laghi
Hip Osteoarthritis
PENG Block vs Suprainguinal FICB vs Lumbar ESPB for Analgesia After Hip Surgery
This randomized, double-blinded, controlled clinical trial compares three motor-sparing regional anesthesia techniques used for postoperative analgesia in patients undergoing hip arthroplasty: the Pericapsular Nerve Group (PENG)…
- Trial name
- NCT07288983
- Testing
- Pericapsular Nerve Group (PENG) Block, Suprainguinal Fascia Iliaca Compartment Block (S-FICB), Lumbar Erector Spinae Plane Block (L-ESPB)
- Where
- Poland
- Volunteers
- 93 people
- Sponsor
- Poznan University of Medical Sciences
Fracture of Ankle
Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block
Patients scheduled to have foot and ankle surgery will typically receive a single shot sciatic nerve block to serve as the primary anesthetic and as part of a multi-modal post-operative analgesic plan.
- Trial name
- NCT01616173
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Postoperative Pain Management, Postoperative Pain
Postoperative Analgesic Efficacy of Modified TAPA and QL Blocks in Laparoscopic Cholecystectomies
Comparison of Postoperative Analgesic Effects of M-TAPA and Anterior Quadratus Lumborum Blocks in Laparoscopic Cholecystectomies.
- Conditions
- Postoperative Pain Management, Postoperative Pain, Analgesia, Nerve Blocks
- Trial name
- NCT06540586
- Testing
- anterior Quadratus lumborum block, M-TAPA BLOCK
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Thoracoscopic Surgery, Nerve Block
Comparison of Analgesic Effect and Postoperative Recovery of SAPB Combined With ESPB and TPB After Thoracoscopic Surgery
After thoracoscopic surgery, patients still face moderate to severe pain. How to effectively control pain and promote postoperative recovery of patients is a challenging problem.
- Trial name
- NCT05538429
- Testing
- erector spinal plane combined with serratus anterior plane block
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Zhangyi
Anesthesia, Radical Mastectomy
Analgesic Efficacy of Ultrasound Guided Serratus Anterior Plane Block and Pectoral Nerve Block II
Modified Radical Mastectomy accounts for 31% of all breast surgeries and considered the fundamental surgical management for breast cancer. Nearly 40-60% of patients experience severe acute postoperative pain.
- Trial name
- NCT06188156
- Testing
- Anethesia
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Al-Azhar University
Inguinal Hernia
Ultrasound-guided Inguinal Field Block (Genitofemoral, Iliohypogastric and Ilioinguinal Nerve Block) for Inguinal Hernia Surgery
The purpose of this study is to investigate the analgesic efficacy of an ultrasound-guided inguinal field block (block of the genitofemoral, iliohypogastric and ilioinguinal nerve).
- Trial name
- U-IFB (NCT01521481)
- Testing
- Triple inguinal nerve block., Unilateral subarachnoid anesthesia
- Where
- Italy
- Volunteers
- 87 people
- Sponsor
- Azienda Ospedaliera San Gerardo di Monza
Pain
Effectiveness of Analgesia in Total Knee Arthroplasty
The purpose of this study is to compare the analgesic effectiveness of three techniques: the femoral nerve block, intraarticular infiltration or a combination of both in the control of pain in total knee arthroplasty (KA).
- Trial name
- ATR-2011 (NCT01304212)
- Testing
- several drugs: morphine chloride,ropivacaine,epinephrine,ketorolac, ropivacaine,morphine chloride,epinephrine,ketorolac, ropivacaine
- Where
- Spain
- Volunteers
- 137 people
- Sponsor
- Jose Antonio Bernia Gil
Prospective, Randomized
The Analgesic Efficacy of Pericapsular Nerve Group (PENG) Block in Patients Undergoing Primary Total Hip Arthoplasty:
The aim of this study is to investigate the analgesic efficacy of the pericapsular nerve group (PENG) block during the implantation of hip endoprostheses.
- Conditions
- Prospective, Randomized, Double-blind
- Trial name
- PENG (NCT06557044)
- Testing
- Ropivacaine, Physiological saline
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Postoperative Pain, Arthroscopic Shoulder Surgery
Comparative Analgesia and Respiratory Effects of Shoulder Blocks
Interscalene block is widely accepted as the gold-standard regional analgesic technique for pain control after arthroscopic shoulder surgery.
- Trial name
- NCT07429669
- Testing
- Interscalene block, Anterior suprascapular block, Pericapsular nerve group (PENG) block
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Upper Limb Surgery, Iliac Crest Bone Harvest
Transversalis Fascial Plane Nerve Block in Iliac Crest Bone Graft
Hand or wrist surgery often requires the use of bony material in order to accomplish any associated reconstructive aspects required for the surgery.
- Trial name
- NCT01133730
- Testing
- Active treatment
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University Health Network, Toronto
Pain, Postoperative, Osteoarthritis, Knee / Osteoarthritis, Hip
iPACK Block vs. Periarticular Infiltration for TKA Pain Control
This study aims to retrospectively compare two different multimodal analgesic techniques for pain management after total knee arthroplasty (TKA).
- Trial name
- NCT07267650
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Turgutlu State Hospital
Block, Analgesia
Comparison of Perioperative Analgesic Efficacy of Femoral Nerve Block, Adductor Canal Block and 4in1 Block
Central neuraxial and regional anesthesia and analgesia techniques significantly reduce perioperative morbidity and mortality in the knee and below-knee surgeries.Nerve blocks appear to have better analgesic efficacy compared to…
- Trial name
- NCT05643040
- Testing
- femoral nerve block, adductor canal block, 4in1 block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital