Clinical trials: Neuropathy (Disorder)
Carpal Tunnel Syndrome, Pain
Effect of Out of Plane and In Plane Injection Techniques in Patients With Carpal Tunnel Syndrome
The aim of this study, using two different injection techniques, 1. To evaluate the patients in terms of the pain they feel during the application of carpal tunnel syndrome (CTS) injection, 2.
- Conditions
- Carpal Tunnel Syndrome, Pain, Carpal Tunnel
- Trial name
- NCT05343351
- Testing
- Technique of injection method
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Leber's Hereditary Optic Neuropathy
A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy
This is a Phase 2, prospective, randomized, double-masked, vehicle controlled, single-center study in approximately 12 subjects with LHON to evaluate safety, tolerability and efficacy of elamipretide (MTP-131) topical ophthalmic…
- Trial name
- NCT02693119
- Testing
- elamipretide (MTP-131) 1% topical ophthalmic solution, Vehicle topical ophthalmic solution
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stealth BioTherapeutics Inc.
Diabetic Neuropathy
Less Neuropathy After Yoga- Managing Diabetic Neuropathy With Yoga
The long-term goal is to identify and establish effective mind-body interventions (as an aspect of complementary and alternative medicine) to improve health and Quality of Life (QoL) for people with disabilities.
- Trial name
- LeNY (NCT02659007)
- Testing
- yoga
- Volunteers
- 15 people
- Sponsor
- Colorado State University
Ischemic Stroke
Effect of EA Combined With NGF on Limb Function in Convalescent Patients With Ischemic Stroke
Most ischemic stroke patients are in recovery phase, often accompanied by motor impairment, but they lack effective treatment. The appearance of nerve growth factor (NGF) promotes the development of neuroprotective therapy, but…
- Trial name
- NCT05652751
- Testing
- nerve growth factor, physiological saline, EA
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Foot Ulcer, Diabetic
Reliability of a Diabetic Foot Ulcer Risk Stratification and Referral Algorithm
The main objective of this research study is to validate the St Joseph's Health Care Harmonized Foot Ulcer Assessment and Stratification tool using inter-rater reliability technique to determine if the score would consistently be…
- Trial name
- NCT03370237
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Diabetic Foot Ulcer, Venous Leg Ulcer
Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs
This is a multicenter, prospective, randomized controlled modified multi-platform (matriarch) trial evaluating several cellular, acellular, and matrix-like products (CAMPs) and standard of care versus standard of care alone in…
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Ulcer Foot, Leg Ulcer
- Trial name
- NCT06560502
- Testing
- Standard of Care-DFU, AmnioCore - DFU, Amnio Quad-Core - DFU
- Where
- United States
- Volunteers
- 324 people
- Sponsor
- Stability Biologics
Carpal Tunnel Syndrome
Efficacy of Hyalase Hydro-dissection in Treatment of Carpal Tunnel: Randomized Double Blind Controlled Clinical Trial
Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy, this study aims to investigate if, and to what extent hydro-dissection hyalase and saline of the median nerve could offer symptoms and clinical improvement
- Trial name
- NCT03675295
- Testing
- Hyalase, Saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM), Amyloidosis
Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis
The study aims to evaluate the effect of acoramidis on cardiac functional and structural improvement in participants with ATTR-CM.
- Conditions
- Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM), Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis
- Trial name
- ASCEND-ATTR (NCT07695701)
- Testing
- Acoramidis (AG10) oral tablet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Eidos Therapeutics, a BridgeBio company
To Prevent Scar Formation for Patients Underwent Surgery
The Effect of Centella Asiatica Cream on Scar Tenderness Who Underwent Open Carpal Tunnel Release Surgery
The centella asiatica cream applied to the wrist after the CTR surgery was found to be beneficial in preventing the scar tenderness in the thenar and hypothenar regions of the hand.
- Trial name
- NCT05017467
- Testing
- undefinedCentella Asiatica Extract
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Mustafa Balevi,MD
Chronic Pain, Chronic Lower Back Pain
Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Effective control of chronic pain is a top priority in the United States, as approximately 10% of adults have severe chronic pain most of which is chronic lower back pain (CLBP).
- Conditions
- Chronic Pain, Chronic Lower Back Pain, Back Pain, Opioid Use
- Trial name
- NCT04156802
- Testing
- Real TBS to the mPFC, Real TBS to the MC
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Wake Forest University Health Sciences
Wound, Venous Leg Ulcer
Geko™ Cross Therapy Registry - Wound
The geko™ Cross Therapy REGISTRY - Wound is a prospective, observational, anonymised data collection Registry with no experimental treatment that will fulfil an unmet need for an observational Registry to provide long-term…
- Conditions
- Wound, Venous Leg Ulcer, Diabetic Foot Ulcer, Arterial Leg Ulcer
- Trial name
- CTR-Wound (NCT05007301)
- Testing
- geko device
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 2,500 people
- Sponsor
- Firstkind Ltd
Multiple Myeloma
CyBorD vs. PAD in the Treatment of Newly Diagnosed Multiple Myeloma
Bortezomib-based triple-drug combination has greatly improved the response rate of multiple myeloma patients. Bortezomib,doxorubicin,and dexamethasone (PAD) is commonly used in clinical practice.Recent studies have found that…
- Trial name
- NCT02362165
- Testing
- Cyclophosphamide, Bortezomib, Dexamethasone
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Sun Yat-sen University
Diabetic Neuropathy, Painful
An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropathic Pain
To test the non-inferiority of duloxetine monotherapy as a treatment for the management of diabetic peripheral neuropathic pain as compared to pregabalin treatment among patients who have not had an adequate response to…
- Trial name
- NCT00385671
- Testing
- duloxetine hydrochloride, pregabalin, gabapentin
- Where
- 9 sites in United States, Germany
- Volunteers
- 407 people
- Sponsor
- Eli Lilly and Company
Piriformis Syndrome
Ultrasound-guided vs. Blinded Dry Needling for Piriformis Syndrome
This randomized controlled trial aims to compare the effectiveness of ultrasound-guided versus blinded dry needling for the treatment of piriformis syndrome.
- Trial name
- NCT05882799
- Testing
- Ultrasound-guided dry needling, Blinded dry needling
- Volunteers
- 60 people
- Sponsor
- Uskudar State Hospital
Low Back Pain, Sciatica
Magnets in the Treatment of Sciatica
Despite much popularity among the public, magnetic devices used for the treatment of various musculoskeletal and neuropathic pain syndromes have been the subject of few randomized controlled trials.
- Trial name
- NCT00044109
- Testing
- Magnets
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Carpal Tunnel Syndrome, Pregnancy Related
Effects of High Intensity Laser on Mechanical and Physiological Findings in Pregnant Women With Carpal Tunnel Syndrome
This study will propose a novel approach to treat pregnant women with mild to moderate carpal tunnel syndrome (CTS) using the recently introduced High intensity laser therapy with its deep penetration and high-power…
- Trial name
- NCT04969393
- Testing
- High intensity laser therapy, Conventional Physical Therapy
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- October 6 University
Carpal Tunnel Syndrome
Median Nerve Strain and Applied Pressure Measurement in the Carpal Tunnel Syndrome Patients
The aim of this study is to investigate diagnostic accuracy of median nerve strain and applied pressure measurement . Idiopathic carpal tunnel syndrome patients and healthy controls will be evaluated by ultrasound.
- Trial name
- NCT04027998
- Testing
- strain and applied pressure measurement
- Where
- Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tokyo Medical University
Unilateral Carpal Tunnel Syndrome
Acute Human Study: StimRouter for Peripheral Nerve Stimulation of Discrete Peripheral Nerves
This study is being done to see how well a new investigational medical device, the StimRouter (STR) System, will work to treat the chronic pain in people who have failed previous treatments for Carpal Tunnel Syndrome (CTS) pain…
- Trial name
- StimRouter (NCT00665132)
- Testing
- StimRouter System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Bioness Inc
Compression Neuropathy, Carpal Tunnel Syndrome
4AP for Carpal Tunnel Syndrome (CTS)
The investigators have found recent promising data supporting the use of a currently FDA approved drug, 4-aminopyridine, in the treatment of nerve injury including compression neuropathy.
- Trial name
- CTS (NCT06294821)
- Testing
- 4-Aminopyridine
- Volunteers
- 160 people
- Sponsor
- John Elfar
Breast Cancer, Pain
Long Term Follow-up of Persistent Pain, Sensory Disturbances and Lymphedema After Breast Cancer Treatment
Persistent pain, sensory disturbances, lymphedema and functional impairment are frequently occurring late effects of breast cancer treatment.
- Conditions
- Breast Cancer, Pain, Post Operative Pain, Lymphedema
- Trial name
- NCT01543711
- Where
- Denmark
- Volunteers
- 2,411 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.