Clinical trials: Noninvasive
Healthy Volunteers
The Effect of Home and Hospital Mask Designs on Respiratory Variables in Healthy Volunteers
The goal of this randomized cross-over study is to investigate whether the design of non-invasive ventilation (NIV) mask impacts respiratory variables in healthy volunteers on NIV therapy.
- Trial name
- NCT07463716
- Testing
- Non-invasive ventilation (NIV)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fisher and Paykel Healthcare
Pulmonary Nodules
A Prospective Cohort Study of Chinese Patients With Pulmonary Nodules: Prediction of Lung Cancer Using Noninvasive Biomarkers
The broad goals of this study is to identify changes in genomic landscape during transition from stage 0 to stage 1 lung cancer.
- Trial name
- NCT04462185
- Testing
- A genomic and transcriptomic landscape analysis
- Where
- 6 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- AnchorDx Medical Co., Ltd.
Noninvasive Mucinous Cystadenocarcinoma of Ovary
Non Ivasive Prenatal Diagnosis (NIPD) of Cystic Fibrosis
The purprose of this study is to develop and validate an analytical and clinical NIPD test for cystic fibrosis from maternal blood by analysis circulating free fetal DNA (cff-DNA), searching for the paternal mutation in families…
- Trial name
- NCT02130648
- Testing
- A sampling of blood
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Glaucoma
Analysis of Translaminar Pressure Gradient Using Noninvasive Cerebrospinal Fluid Pressure Monitoring
This is a single center, prospective study to calculate cerebrospinal fluid pressure (CSFp) using a non-invasive device and assess its role in the development of optic neuropathy due to glaucoma or idiopathic intracranial…
- Trial name
- NCT02828891
- Testing
- Two-Dimensional Transcranial Doppler
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Skin Lesion, Mucosal Lesion
A Study of Noninvasive Methods to Evaluate Skin and Mucosal Conditions
The purpose of this study is to find out whether using noninvasive methods to study the appearance of lesions can improve diagnostic accuracy before a biopsy is required and help guide treatment planning.
- Trial name
- NCT04743362
- Testing
- Dermoscopic imaging, 3-dimensional total body photography, Confocal microscopy
- Where
- United States
- Volunteers
- 5,010 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Normal Aging
Noninvasive Brain Stimulation to Enhance Cognitive Training in Older Adults
This research study explores the feasibility of pairing computer-based cognitive training (CBCT) with transcranial direct current stimulation (tDCS), a form of non-invasive brain stimulation, in order to enhance and preserve…
- Trial name
- MINDS (NCT04050046)
- Testing
- Transcranial Direct Current Stimulation, Computer-based cognitive therapy (CBCT)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
STEMI - ST Elevation Myocardial Infarction
Noninvasive Artificial Venous Stasis for Reperfusion in STEMI
This prospective, randomized study was designed to evaluate whether the noninvasive artificial venous stasis / RE-START procedure, administered prior to primary percutaneous coronary intervention, increases the frequency of…
- Trial name
- RE-START (NCT07689591)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Firat University
Hepatic Steatosis, Obesity, Childhood
Attenuation Imaging in Hepatic Steatosis
For obese and normal-weight children, the investigators assess the diagnostic performance of attenuation imaging (ATI) in the detection of hepatic steatosis in children.
- Conditions
- Hepatic Steatosis, Obesity, Childhood, Ultrasonography
- Trial name
- NCT05302258
- Testing
- Attenuation imaging in ultrasonography
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Facial Aging, Skin Laxity
Quantified Evaluation of Noninvasive System Delivering Microwave Energy for Unwanted Fat Reduction and Skin Tightening in Asians.
The goal of this observational study is to evaluate the effectiveness and safety of microwave-assisted heating technology in facial fat reduction and skin tightening in Asians. The main questions it aims to answer are: 1.
- Conditions
- Facial Aging, Skin Laxity, Cheek Wrinkles
- Trial name
- NCT06925074
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chang Chang Cheng
Chronic Lung Disease
Utility of Lung Clearance Index Score as a Noninvasive Marker of Small Airways Disease
To determine the utility and sensitivity of the lung clearance index (LCI) technique as a marker of small airways disease in adults with chronic lung conditions compared to healthy adults, adjusting for age, sex and smoking…
- Trial name
- NCT03241420
- Testing
- lung clearance index (LCI)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
OCD, Decision-Making
Arbitration Between Habitual and Goal-directed Behavior in Obsessive-compulsive Disorder: Circuit Dynamics and Effects of Noninvasive Neurostimulation
People utilize two behavioral strategies, goal-directed and habitual, when engaging in value-based decision-making that involves rewarding or punishing outcomes.
- Conditions
- OCD, Decision-Making, tDCS, fMRI
- Trial name
- NCT04075890
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Alzheimer Disease
Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation
The investigators will evaluate the theory that Alzheimer's disease-related memory impairment derives from the inefficient orchestration of rhythmic activity at the level of large-scale cortical networks.
- Trial name
- NCT06094192
- Testing
- High definition transcranial electrical current stimulation
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Abdominal Fat
A Pilot Study Testing a Noninvasive Cryolipolysis Device Versus a High Intensity Focused Ultrasound Device for Fat Reduction
The purpose of this study is to compare the safety and effectiveness of the Zeltiq System and LipoSonix System for fat reduction and improving body shape.
- Trial name
- NCT01976247
- Testing
- High Intensity Focused Ultrasound Device, Noninvasive Cryolipolysis Device
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pregnancy Related
Cell- Based Noninvasive Prenatal Testing (NIPT): Single Cell Prenatal Diagnosis (SCPD)
The purpose of the overall study is to develop improved methods for recovery of fetal cells from the mother's blood in order to develop a clinically useful form of cell-based, diagnostic, noninvasive prenatal testing (NIPT).
- Trial name
- NIPT & SCPD (NCT05076734)
- Testing
- Redraw for analysis of blood samples from healthy pregnant women
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Luna Genetics
Isolated Focal Hand Dystonia
Neuromodulation Therapy for Task-Specific Dystonia
This study aims to apply a non-invasive brain stimulation technology called repetitive Transcranial Magnetic Stimulation (rTMS) in patients with focal hand dystonia (FHD).
- Trial name
- NCT06422104
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Duke University
Prediabetic State, Diabetes Mellitus, Type 2
Noninvasive Skin Spectroscopy for Diabetes Screening
The objective of this study is to assess the performance of a noninvasive device for the early screening of Diabetes Mellitus.
- Trial name
- NCT00358254
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- InLight Solutions
COPD
Feasibility of Noninvasive Trigeminal Nerve Stimulation During Exercise
The purpose of this study is to examine 1) effects of cutaneous electrical trigeminal nerve stimulation (eTNS) on respiratory control in healthy volunteers and 2) explore the potential of this approach to mitigate dyspnea in…
- Trial name
- NCT07686302
- Testing
- Active Stimulation, Fan therapy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Thoracic Surgery
Electrical Impedance Tomography in Evaluating the Effects of Noninvasive Ventilation in Post-Operative Cardiac Surgery
NTRODUCTION: cardiac surgery can lead to pulmonary complications such as hypoxemia and atelectasis. Noninvasive ventilation has been used to prevent and treat such complications.
- Trial name
- NCT03371628
- Testing
- Non invasive ventilation
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Healthy
Comparison of Noninvasive Hemoglobin Disposable Sensors
In this study, the concentration of hemoglobin within the subject's blood will be reduced in a controlled manner by administering fluids intravenously.
- Trial name
- NCT03125031
- Testing
- Rainbow adhesive adult/pediatric sensor, Rainbow adhesive adult/neonatal sensor
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Sports Performance
The Effect of Vagus Nerve Stimulation on Sportive Performance.
Performance is defined as the physiological potential required for an individual's physical activity. The sportive activity that he creates with his potential is defined as the sportive performance level of the individual.
- Trial name
- NCT05436821
- Testing
- Auricular vagus nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- İSMAİL CEYLAN