Clinical trials: Osteoarthritis Arthritis
Knee Osteoarthritis
Staged Versus Simultaneous Bilateral Knee Arthroplasty
The purpose of this study is to assist surgeons and patients in answering the question "Should I have both knees replaced at the same time, or should I just do one and wait to do the second one?"
- Trial name
- NCT03564730
- Testing
- Simultaneous Knee Arthroplasty (UKA), Staged Knee Arthroplasty (UKA)
- Where
- 8 sites in Canada
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Innovation Centre
Osteo Arthritis Knee, Pain, Chronic
Study of the Effects of Photobiomodulation in Patients With Osteoarthritis
PhotoBioModulation (PBM) is a mature science with therapeutic efficacy in humans and animals, and with excellent results in different medical specialties without side effects.
- Conditions
- Osteo Arthritis Knee, Pain, Chronic, Inflammation
- Trial name
- NCT03924128
- Testing
- Photobiomodulation
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Knee Osteoarthritis
Autologous Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis
Knee osteoarthritis (OA) is characterized by loss of cartilage leading to instability, reduced range of motion, and functional limitations.
- Trial name
- NCT03788265
- Testing
- Lipogems
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hip Osteoarthritis, Knee Osteoarthritis
Golf After Orthopaedic Surgery: A Longitudinal Follow-up (GOLF) Study
Aims The primary aim of this prospective, multi-centre study is to describe the rates of returning to golf following hip, knee and shoulder arthroplasty in an active golfing population.
- Conditions
- Hip Osteoarthritis, Knee Osteoarthritis, Shoulder Osteoarthritis
- Trial name
- NCT05676567
- Where
- United Kingdom
- Volunteers
- 124 people
- Sponsor
- University of Edinburgh
Osteo Arthritis Knee, Knee Osteoarthritis
Knee Arthritis Treatment With Autologous Fragmented Adipose Tissue and PRP - Comparison of Two Treatment Methods
This is a prospective, randomized, controlled study. The purpose of this study is to assess functional and clinical changes among patients with symptomatic knee OA treated with intra-articular injections of autologous adipose…
- Conditions
- Osteo Arthritis Knee, Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT04321629
- Testing
- autologous adipose tissue transfer, PRP injections
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Rehasport Clinic
Osteoarthritis, Rheumatoid Arthritis
6 Week Open-label Trial With Lumiracoxib 200mg o.d. in Primary Knee Osteoarthritis or Rheumatoid Arthritis
This study tested the safety, tolerability and efficacy of lumiracoxib - a COX-2 inhibitor- in patients with primary knee osteoarthritis or rheumatoid arthritis.
- Trial name
- NCT00170872
- Testing
- Lumiracoxib
- Volunteers
- 135 people
- Sponsor
- Novartis
Osteoarthritis, Pain
Evaluation of the Effectiveness, Compliance of Ibuprofen in a Sustained Release Form in the Treatment of Egyptian Osteoarthritic Patients
This is a prospective, multi-center, post-marketing observational study to evaluate the effectiveness and compliance of ibuprofen in a sustained release form in the treatment of Egyptian osteoarthritic patients.
- Conditions
- Osteoarthritis, Pain, Morning Stiffness
- Trial name
- NCT01226095
- Where
- 15 sites in Egypt
- Volunteers
- 519 people
- Sponsor
- Abbott
Knee Osteoarthritis, Gonarthrosis
Knee Joint Position Sense in Knee Osteoarthritis
The aim of this study was to compare knee joint position sense between sitting with visual input and prone without visual input in individuals with knee osteoarthritis.
- Trial name
- NCT07386977
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Lokman Hekim University
Knee Osteoarthritis
Early Outcomes of MAKO Medial Unicompartmental Knee Arthroplasty
To determine if robotically-assisted UKA results in more consistent and improved component positioning and better patient reported outcome scores compared to manual TKA and MAKO TKA.
- Trial name
- NCT05736601
- Testing
- focus motion knee brace
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Washington University School of Medicine
Osteoarthritis
Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
There are two cartilage structures, called menisci, in each knee joint. A torn meniscus can be caused by a traumatic injury or aging-related degeneration.
- Trial name
- NCT00597012
- Testing
- Arthroscopic partial menisectomy, Standard physical therapy, Postoperative rehabilitative physical therapy
- Where
- 7 sites in United States
- Volunteers
- 351 people
- Sponsor
- Brigham and Women's Hospital
Assessment of the Trophic and Anti-inflammatory Effect of SVF Added With HPL
Evaluation of Enhanced Therapeutic Effect of Adipose Stromal Vascular Fraction Added With Human Platelet Lysate in Treatment of Osteoarthritis
Osteoarthritis (OA) is a highly progressive and debilitating joint disease. Recently, it was demonstrated the existence of an important link between OA inflammation and progression of structural changes.
- Trial name
- NCT04225481
- Testing
- isolation of waste material and culturing with different supplement culture media
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Osteoarthritis, Knee, Knee Pain
The Effect of Micro Fragmented Adipose Tissue (MFAT) on Knee Osteoarthritis
This is a non-surgical trial comparing the clinical and functional outcomes of patients with osteoarthritis treated with Intra-articular injection of Micro Fragmented Adipose Tissue versus conventional therapy of intra-articular…
- Trial name
- NCT03467919
- Testing
- Micro Fragmented Adipose Tissue, Corticosteroid injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Unilateral Knee Osteoarthritis
Assessing the Impact of Isokinetic Muscular Strengthening in Eccentric Mode in the Medical Treatment of Knee Osteoarthritis
Knee osteoarthritis (O.A. from now on) is associated to muscular weakness of inferior limbs, especially the quadriceps; leading to disease progression.
- Trial name
- ISOGO (NCT01586130)
- Testing
- Exercise in eccentric or concentric mode
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Knee Osteoarthritis
Treatment of Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells
The purpose of this study is to explore the efficacy and safety of autologous adipose-derived mesenchymal stem cells (AMSCs) plus autologous platelet rich plasma (PRP) in the treatment of severe knee osteoarthritis.
- Trial name
- NCT04212728
- Testing
- Auotologous AMSCs plus autologous PRP, Auotologous PRP
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yantai Yuhuangding Hospital
Knee Osteoarthritis, Osteoarthritis (OA)
Clinical Outcomes of Intraarticular Platelet-Rich Plasma Injection in Knee Osteoarthritis
This prospective single-arm interventional study was designed to assess the short-term clinical outcomes of intra-articular platelet-rich plasma (PRP) injections in patients with Kellgren-Lawrence grade II and III knee…
- Conditions
- Knee Osteoarthritis, Osteoarthritis (OA), Degenerative Joint Disease of Knee, Knee Pain
- Trial name
- NCT07828561
- Testing
- Platelet-Rich Plasma (PRP)
- Where
- Nepal
- Volunteers
- 59 people
- Sponsor
- KIST Medical and Teaching Hospital
Knee Arthritis Osteoarthritis
Laser vs Lontophoresis in KOA
This randomized controlled trial aims to compare the effectiveness of laser therapy and iontophoresis in patients with knee osteoarthritis.
- Trial name
- NCT07666061
- Testing
- Low-Level Laser Therapy, Iontophoresis, Conventional Physical Therapy Only
- Volunteers
- 66 people
- Sponsor
- Kafrelsheikh University
Knee Osteoarthritis
Comparative Effect of Dual Task Training and Rhythmic Stabilization in Knee Osteoarthritis Patients
Knee osteoarthritis (KOA) is a degenerative joint condition that causes pain, stiffness, reduced proprioception, impaired balance, and decreased physical function.
- Trial name
- NCT07913295
- Testing
- Dual task training, Rhythmic stabilization
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- University of Management and Technology Lahore
Hypertension, Diabetes
Exercise Impact in Elderly With Multimorbidity: HbA1c and Blood Pressure
The main objective of the study is to compare the effect of two different types of physical exercise modalities on glycated hemoglobin and blood pressure in elderly individuals with multimorbidity.
- Conditions
- Hypertension, Diabetes, Osteoarthritis, Depression Disorders
- Trial name
- NCT06879639
- Testing
- Exercise, Control
- Where
- Portugal
- Volunteers
- 63 people
- Sponsor
- Universidade do Porto
Knee Osteoarthritis
The Effectiveness of Kinesio Taping Method for Knee Osteoarthritis.
Purpose of our study is to evaluate effectiveness of Kinesio Taping method for knee osteoarthritis. Using simple concealed randomization procedure to form two groups (kinesio taping and control-nonspecific taping) of 100 knee…
- Trial name
- NCT03076177
- Testing
- Taping application
- Where
- Lithuania
- Volunteers
- 187 people
- Sponsor
- Lithuanian University of Health Sciences
Osteoarthritis
A Phase I, Prospective, Randomized, Open-label, Active-Controlled Clinical Trial for Safety Evaluation of Intra-articular Injection of RegenoGel-SP for the Treatment of Moderate to Severe Osteoarthritis
This is a Phase I, prospective, active-controlled, randomized, open-label, clinical trial designed to assess the safety and tolerability of single intra-articular injection of RegenoGel-SP for the treatment of OA.
- Trial name
- NCT02188771
- Testing
- intra-articular administration of RegenoGel-SP or hyaluronic acid (HA)
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- ProCore Ltd.
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