Clinical trials: Pain Thresholds
University Students, Health-related Lifestyle Factors
Health-Related Lifestyle Factors, Sex, and Neural Mechanosensitivity in University Students
This observational cross-sectional study aims to investigate the effects of health-related lifestyle factors and sex on neural mechanosensitivity in university students.
- Conditions
- University Students, Health-related Lifestyle Factors, Neural Mechanosensitivity
- Trial name
- NCT07511452
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Neck Pain
Body Composition and Cervical Outcomes in Non-Specific Neck Pain
Non-specific neck pain (NSNP) is a common musculoskeletal condition that significantly affects quality of life, daily activities, and work productivity.
- Trial name
- NCT07388706
- Testing
- Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Basic Physiology, Brain Stimulation
Transcranial Direct Current Stimulation (tDCS) in the Primary Motor Cortex in Healthy Individuals
The main aim of this study is to assess the short-term effects of active-tDCS (a-tDCS) on the M1 regarding sensorimotor variables such as discriminative sensation, pressure pain threshold and electromyographic activity compared…
- Trial name
- NCT04148547
- Testing
- Sooma transcranial direct current stimulation device
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Pain, Acute, Muscle Soreness
Analgesic Induces Similar Upper and Lower Body Pain Pressure Threshold Increases
Background: Both health professionals and consumers use menthol-based topical analgesics extensively for the temporary relief of pain from musculoskeletal ailments or injury.
- Conditions
- Pain, Acute, Muscle Soreness, Tendon Injuries
- Trial name
- NCT04677985
- Testing
- Menthol based topical analgesic
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Neck Pain
Immediate Effects Cervicothoracic Manipulation Versus Passive Upper Trapezius Stretch
The proposed project seeks to evaluate the influence of cervicothoracic (CT) manipulation and passive stretching to the upper trapezius on pressure pain thresholds and range of motion (ROM) in individuals without recent complain…
- Trial name
- NCT02552290
- Testing
- Upper Trapezius Stretch, Cervicothoracic manipulation, No intervention
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Pain, Physical Activity
Influence of Expectations on Change in Pain Perception After a 3 Min Wallsquat Exercise.
The purpose of this study is to investigate how expectations induced by information given prior to exercise influence the magnitude of exercise-induced hypoalgesia after a 3 min wallsquat exercise in healthy subjects.
- Trial name
- NCT03678662
- Testing
- Hypoalgesia expectation, Hyperalgesia expectation, Neutral
- Where
- Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hyperalgesia, Pain Insensitivity, Congenital
The Relationship Between Saliva β-endorphins Levels, Cold Pressor Test and Perception of Pain in Oral Surgery Procedures
The purpose of this study is to evaluate the correlation between β-endorphin levels in blood plasma and saliva in healthy participants with different pain sensitivity and in those with acute pain in oral and maxillofacial region.
- Trial name
- NCT03164161
- Testing
- Cold pressor test, β-endorphins evaluation in saliva, β-endorphins evaluation in blood plasma
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Healthy
The Effects of Hamstring Stretching With and Without Neural Load on Flexibility, Maximum Isometric Strength and Tibial Nerve Pressure Pain Threshold
The study will be carried out at the Faculty of Nursing and Physiotherapy of the University of Alcala. The study has been approved by the Animal Research and Experimentation Ethics Committee of the University of Alcalá.
- Trial name
- NCT05344586
- Testing
- Hamstring stretching program with neural load, Hamstring stretching program without neural load
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Pain Thresholds, Healthy Adult Participants
Evaluation of Psychophysical Responses After Mechanical Stimulation.
This study evaluates the test-retest reliability of psychophysical responses to non-injurious sharp stimuli applied via a robotic system.
- Trial name
- NCT07774429
- Testing
- Robot-controlled non-injurious mechanical stimulation
- Where
- Argentina
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Office Worker, Myofascial Pain Syndrome (Upper Trapezius)
Predictors of Pressure Pain Thresholds
Objective: This cross-sectional study aimed to determine whether office-related strain risk, head and neck working posture, and weekly screen time predict the mean pressure pain threshold (PPT) at latent trigger points (LTrPs) in…
- Conditions
- Office Worker, Myofascial Pain Syndrome (Upper Trapezius), Pain Threshold, Trigger Points, Myofascial
- Trial name
- NCT07874230
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Neuropathy, Diabetic, Neuropathy, Painful
Methods of Early Detection and Grading Of Diabetic Peripheral Neuropathy (MEDON)
MEDON aims to examine new methods for early detection and grading of diabetic peripheral neuropathy focusing on both small- and large nerve fibers.
- Trial name
- MEDON (NCT04078516)
- Testing
- Perception Threshold Tracking (PTT), Axon-flair mediated respons, Heart rate variability
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Myofascial Trigger Point Pain (MTrP)
Percutaneous Microelectrolysis on Myofascial Trigger Points Pain.
The aim of the design is to investigate the value of percutaneous microelectrolysis (MEP) as an analgesic technique in myofascial trigger points.
- Trial name
- MEP (NCT03636386)
- Testing
- Percutaneous microelectrolysis, Ultrasound therapy
- Where
- Chile
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Quiropraxia y Equilibrio
Pain Threshold, Pain Tolerance
Acute Effects of LLLT on Pain Threshold and Pain Tolerance
Pain is defined by the International Association for the Study of Pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage." Low-Level Laser…
- Conditions
- Pain Threshold, Pain Tolerance, Acute Pain, Low-level Laser Therapy
- Trial name
- NCT07422272
- Testing
- Low-Level Laser Therapy (LLLT)
- Where
- Cyprus
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- European University of Lefke
Low Back Pain
Characterizing the Role of Pain Sensitivity in Acute to Persistent Low Back Pain
This research study will examine whether enhanced pain sensitivity increases the risk of persistent low back pain. The study will address the highly prevalent and costly condition of persistent low back pain and a major obstacle…
- Trial name
- NCT01981382
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Low Back Pain
Immediate Effect of Dry Needling of the Lumbar Multifidus on Pain Sensitivity In A Healthy Population
The goal of this interventional study is to test the effects of trigger point dry needling to the low back in a healthy population.
- Trial name
- NCT05845697
- Testing
- Trigger point dry needling
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Hyperalgesia
Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids
This research study explores whether a beta-blocker (propranolol) can prevent a person from becoming more sensitive to pain after administration of an opioid (remifentanil).
- Trial name
- NCT01222091
- Testing
- Propranolol, Remifentanil
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pain
Oxytocin and Pain Sensitivity and Threshold
Oxytocin is neurohypophysial peptide that acts mainly as a neuromodulator in the brain. In addition,oxytocin have an important roles in sexual reproduction , in particular during and after childbirth.
- Trial name
- NCT01988649
- Testing
- Intranasal Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Dyspareunia
What is the Nature of Pelvic Floor Muscle Involvement in Dyspareunia?
Dyspareunia, or pain experienced by women during penetrative sexual activities, affects the psychological and sexual health of more than one in five Canadian women [1], yet its pathophysiology is poorly understood [2-4] and…
- Trial name
- NCT04234555
- Testing
- Corticomotor excitability to the pelvic floor muscles, Pelvic floor muscle response to pressure applied at the vulvar vestibule, Pressure pain threshold (PPS)
- Where
- Canada
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Pain
Evaluating VR Therapy Using Cold Pressor Test
This study is testing whether or not low-cost, virtual reality (VR) headsets for mobile phones can be used as a potential distractor from pain and thus would have clinical applications as a low-cost, non-pharmaceutical method to…
- Trial name
- NCT03268863
- Testing
- Virtual Reality, Cold Pressor
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Janet Vittone
Pain, Anxiety
The Effect of State and Trait Anxiety on Pain-pressure Threshold
The purpose of this research is to find out if different types of anxiety impact the sensation of how sensitive various muscles are to the application of pressure.
- Conditions
- Pain, Anxiety, Musculoskeletal Pain, Sensitisation
- Trial name
- NCT06047704
- Testing
- No intervention
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Philadelphia College of Osteopathic Medicine