Clinical trials: Patient Ventilator Interactions
Patient Ventilator Interactions
Analysis and Evaluation of Asynchronies Between NIV Patients and Their Prisma VENT or LUISA Ventilator
This study aims to analyze the types, rates, and patterns of disturbances between the breathing of patients receiving non-invasive ventilation and their ventilator (patient-ventilator asynchronies, PVA) during routine therapy…
- Trial name
- NCT07768748
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Löwenstein Medical Technology GmbH & Co. KG
Acute Hypercapnic Respiratory Failure
Sedation During Noninvasive Ventilation (NIV)
In patients undergoing NIV for acute respiratory, lack of tolerance is one of the main reason of failure. This may result in a poor synchrony between the patient and the machine, leading to gross mismatching and potentially to an…
- Trial name
- REMI (NCT02264626)
- Testing
- Remifentanil
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Dyspnea
Patient Dyspnea Under Veno-arterial Extracorporeal Circulation
Rationale: Patients with severe heart failure increasingly benefit from extracorporeal circulatory assistance (Extracorporeal Membrane Oxygenation - ECMO) that completely replaces the function of the heart and is in addition to…
- Trial name
- DYSCO2 (NCT04815330)
- Testing
- increment sweep gas flow, non-invasive ventilation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome
Patient -Ventilator Interaction in Chronic Respiratory Failure
To evaluate a novel advanced physiological monitoring system to improve nocturnal non-invasive ventilation (NIV) in Neuromuscular disease (NMD), Chest wall disease (CWD), Chronic Obstructive Pulmonary Disease (COPD) and Obesity…
- Conditions
- Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome, Neuromuscular Disease, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01371149
- Testing
- Surface parasternal electromyography (EMG) set up
- Where
- 2 sites in United Kingdom
- Volunteers
- 58 people
- Sponsor
- Michelle Ramsay
Chronic Hypercapnic Respiratory Failure
Patients-ventilator Interaction During Sleep: Effect of Humidification System
At present, little data is available in the medical literature regarding the affects of humidification on NIMV efficacy, sleep quality and upper airway symptoms in patients undergoing nocturnal NIMV.
- Trial name
- NCT01038791
- Testing
- heated humidification, heat and moisture exchanger, usual mechanical ventilation without humidification
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Mechanical Ventilation Complication
Automated Detection of Patient Ventilator Asynchrony Using Pes Signal
Rationale: Patient-ventilator asynchrony (PVA) in mechanical ventilation is associated with adverse patient outcome such as a prolonged stay in the ICU and even mortality.
- Trial name
- NCT06186557
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Leiden University Medical Center
Obesity, Non Invasive Ventilation
Patient-ventilator Interactions in Long Term Non-invasive Ventilation: Influence of Back-up Frequency
In patients under bi-level pressure support ventilation for obesity hypoventilation syndrome, this study aims to determine if it is better, in terms of efficacy and patient-ventilator synchronisation to use Spontaneous mode (S)…
- Trial name
- NCT01130090
- Testing
- Adjustment of back-up respiratory rate on bi-level ventilator
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Ligue Pulmonaire Genevoise
ARDS, Human
EIT in Patient Ventilator Asynchrony
Patient-ventilator asynchrony is an important clinical issue in mechanically ventilated patients. For patients with moderate to severe acute respiratory distress syndrome (ARDS), various types of patient ventilator asynchrony may…
- Trial name
- NCT04442815
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Cheng-Kung University Hospital
Chronic Obstructive Pulmonary Disease
Patient-Ventilator Interactions in Chronic Obstructive Pulmonary Diseases (COPD) Under Non-Invasive Ventilation
Non-invasive ventilation (NIV) in severe hypercapnic Chronic Obstructive Pulmonary Diseases (COPD) may be associated - during sleep - with recurrent episodes of patient ventilatory asynchrony, which in turn may affect quality of…
- Trial name
- NCT01180439
- Testing
- Adjustment of ventilator settings (device)
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Ligue Pulmonaire Genevoise
Non Invasive Ventilation, Patient Ventilator Interaction
Neurally Adjusted Ventilatory Assist for Non Invasive Ventilation and Patient-ventilator Interaction
The present study aims to compare various parameters reflecting patient-ventilator synchrony during standard pressure support (PS) and Neurally Adjusted Ventilatory assist (NAVA) in a group of patients receiving non invasive…
- Trial name
- NCT01074866
- Testing
- Neurally Adjusted Ventilatory Assist
- Where
- 4 sites in Belgium, Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Geneva
Acute Respiratory Failure With Hypoxia
NAVA Helmet in Pediatric Respiratory Failure
Neurally Adjusted Ventilatory Assist (NAVA) is a new form of partial support wherein the machine applies positive pressure throughout inspiration in proportion to the electrical activity of the diaphragm (EAdi), Because…
- Trial name
- NCT02050217
- Testing
- Neurally Adjusted Ventilatory Assist
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Distress Respiratory Syndrome, Weaning Failure
Pressure Support Ventilation Versus Neurally Adjusted Ventilatory Assist in Difficult to Wean Pediatric Patients
This study assessed the effects of NAVA versus Pressure Support Ventilation (PSV) on patient-ventilator interaction in pediatric patients with difficult weaning from mechanical ventilation after moderate Pediatric Acute…
- Trial name
- NCT04360590
- Testing
- pressure support ventilation versus neurally adjusted ventilatory assist
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Acute Respiratory Failure, Mechanical Ventilation Complication
New Setting of Neurally Adjusted Ventilatory Assist During Mask Noninvasive Ventilation
Non invasive ventilation (NIV) is generally delivered by pneumatically triggered and cycled-off Pressure Support (PSP) through a facial mask.
- Trial name
- NCT03041402
- Testing
- PSP, NAVA, PSN
- Volunteers
- 14 people
- Sponsor
- Southeast University, China
Respiratory Failure, Mechanical Ventilation Complication
Patient-ventilator Interaction During NIV With Helmet: a Comparison Between PSV and the New NIV NPS Software
The goal of this clinical trial is to evaluate if neural pressure support ventilation is able to improve patient-ventilator synchrony, in ICU patients undergoing non-invasive ventilation (NIV).
- Trial name
- NCT06004206
- Testing
- nPSV and PSV
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- ASL Novara
Patient Ventilator Interactions, Spontaneous Breathing Trial
Entropy Analysis and Complex Patient-ventilator Interactions During Mechanical Ventilation
Complex patterns of patient-ventilator interactions could be miscalculated by visual observation of mechanical ventilator screens or current algorithms based on physiologic waveforms to detect patient-ventilator asynchronies.
- Trial name
- ENTROPY-ICU (NCT04128124)
- Testing
- processing signals of airway pressure and airway flow to calculate entropy
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- Corporacion Parc Tauli
Respiratory Distress Syndrome, Newborn, Infant, Premature
Neural Control of Non-invasive Ventilation in the Preterm
The present study will use a new type of respirator in premature babies who need help with their breathing. This new respirator uses signals from the baby's diaphragm - the most important breathing muscle - to control the timing…
- Trial name
- NCT00368485
- Testing
- Neurally Controlled Mechanical Ventilation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Dyspnea
Impact of Proportional Assisted Ventilation on Dyspnea and Asynchrony in Mechanically Ventilated Patients
Rational. The mismatch between the activity of the respiratory muscles and the assistance delivered by the ventilator results in patient-ventilator disharmony, which is commonly observed in ICU patients and is associated with…
- Trial name
- DYS-PAV (NCT02801994)
- Testing
- PAV, Puritan Bennett 980 ventilator
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Dyspnea
Sensory and Emotional Modulation of Dyspnea Under Artificial Ventilation in the Intensive Care Unit
Rationale: Half of the patients receiving mechanical ventilation in the intensive care unit (ICU) have moderate to severe dyspnea.
- Trial name
- Sensopnée2 (NCT04815317)
- Testing
- Auditive stimulation, Sensitive stimulation, Auditory control
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Respiratory Failure
Comparative Effects of Variable Pressure Support, NAVA and PAV
Experimental animal data suggest that increasing breathing pattern variability in mechanical ventilation could be beneficial. Variable ventilation can be induced through the following modes: Neurally Adjust Ventilatory Assist…
- Trial name
- NCT02499276
- Testing
- PSV, NAVA, PAV, Variable-PSV
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Acute Respiratory Failure
Adjusted Ventilatory Assist (NAVA-NIV) in Infants: Short-term Physiological Study
Neurally Adjusted Ventilatory Assist (NAVA) is a new form of partial support wherein the machine applies positive pressure throughout inspiration in proportion to the electrical activity of the diaphragm (EAdi), as assessed by…
- Trial name
- NCT02043990
- Testing
- Noninvasive NAVA ventilation
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico