Clinical trials: Periodontal Pocket, open to volunteers
Peri-Implantitis
Management of Peri-implantitis: Non-surgical Treatment of Peri-implantitis.
The goal of this clinical trial is to compare non-surgical treatment by mechanical debridement with air-polishing in peri-implantitis.
- Trial name
- NCT05683405
- Testing
- Non-surgical treatment of peri-implantitis with mechanical debridement, Non-surgical treatment of peri-implantitis with air polishing
- Where
- Norway
- Volunteers
- 88 people
- Sponsor
- Tannhelsetjenestens Kompetansesenter for Nord-Norge
Periodontitis, Periodontal Diseases
NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration
Three techniques for periodontal reconstruction will be compared, in which marginal access versus apical access will be carried out.
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket
- Trial name
- NCT03997552
- Testing
- Non-incised papillae surgical approach (NIPSA), marginal approach by palatal incision, Minimally invasive surgical technique (MIST)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Murcia
Third Molar Impaction, Surgical Extraction of Impacted Third Molars
The Effect of Platelet Rich Fibrin On Sensitivity and Periodontal Pockets Distal to Second Molar After Surgical Extraction of Impacted Third Molar
Surgical extraction of impacted third molar is the most common surgical procedure performed in oral and maxillofacial surgery. The immediate post operative complications after 3rd molar surgery are pain, swelling and trismus…
- Trial name
- NCT07351279
- Testing
- Platelet rich fibrin
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- University of Health Sciences Lahore
Periodontitis
Non-Surgical Treatment of Periodontitis With Adjunctive Sodium Hypochlorite/Amino Acids and Cross-Linked Hyaluronic Acid
The goal of this clinical trial is to learn if using sodium hypochlorite/amino acid gel, with or without cross-linked hyaluronic acid, as an addition to standard non-surgical periodontal therapy works to treat periodontitis in…
- Trial name
- NCT07474272
- Testing
- Standard Non-Surgical Periodontal Therapy, tandard Therapy + Sodium Hypochlorite/Amino Acid Gel, Standard Therapy + Sodium Hypochlorite/Amino Acid Gel + Cross-Linked Hyaluronic Acid
- Where
- Lebanon
- Volunteers
- 78 people
- Sponsor
- Marwan El Mobadder
Periodontal Diseases, Periodontal Pocket
Occlusal Load Distribution and Periodontal Status
Occlusal forces are unevenly distributed among teeth during mastication, potentially predisposing certain teeth to higher functional loads.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Periimplantitis
- Trial name
- Perio-Occlusio (NCT07199062)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Periodontitis, Periodontitis and Treatment Need
Dental Loupe Versus Dental Operating Microscope for Non-Surgical Periodontal Treatment
Periodontitis is a multifactorial, non-infectious disease that can lead to tooth loss if left untreated. Advanced stages of periodontitis can affect chewing ability, nutritional status, and quality of life.
- Conditions
- Periodontitis, Periodontitis and Treatment Need, Periodontal Disease, Periodontal Pocket
- Trial name
- NCT07822269
- Testing
- Mechanical debridement and dental plaque sample collection with dental loupe, Mechanical debridement and dental plaque sample collection with dental microscope
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Periodontitis
Granulation Tissue From Residual Periodontal Pockets
This observational study aims to describe the histopathological features of granulation tissue (GT) found in residual periodontal pockets at the time of surgical intervention, after completion of the first two steps of…
- Trial name
- GTRP (NCT07587606)
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- University of Roma La Sapienza
Infra-bony Periodontal Defect
Effect of Gingival Mesenchymal Stem Cell-Derived Small Extracellular Vesicles in Management of Infra-bony Periodontal Defect
The goal of the study to evaluate whether the adjunctive use of gingival mesenchymal stem cell-derived extracellular vesicles (GMSC-derived EVs) combined with β-tricalcium phosphate (β-TCP) and a collagen membrane results in…
- Trial name
- NCT07867067
- Testing
- Gingival mesenchymal stem cell derived small extracellular vesicles, β-calcium triphosphate (β-TCP) + collagen membrane
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Ain Shams University
Periodontal Diseases, Periodontal Pocket
Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization
This study is being performed to compare different methods of visualization during routine gum surgery. The gum surgery is standard of care.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Periodontal Inflammation
- Trial name
- NCT05932017
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Bone Loss, Pocket, Periodontal
Influence of Acetal Resin Versus Nylon Elastic Cap on Crestal Bone Loss in Mandibular Implant-Supported Overdenture
Objective: To evaluate and compare the effect of two different attachment housing materials-Acetal Resin (Polyoxymethylene) versus conventional Nylon elastic caps-on marginal crestal bone loss around dental implants supporting a…
- Trial name
- AcetalResin (NCT07666763)
- Testing
- Acetal Resin, nylon
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Periodontal Diseases, Gingival Diseases
Novel Dental Gel as an Adjunct to Scaling and Root Planing
This study will evaluate the use of Livionex Dental Gel (LDG) as a home care product in reducing probing pocket depth (PD) beyond the effect achieved by the current standard of care with SRP in periodontitis patients.
- Conditions
- Periodontal Diseases, Gingival Diseases, Gingival Pocket, Gum Bleed
- Trial name
- NCT05384132
- Testing
- SRP + Livfresh Dental Gel, SRP + standard flouride dentifrice
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Periodontitis
Diode Laser 635 nm and 810 nm Photodynamic Therapy as Adjuncts to Non-Surgical Periodontal Treatment
This study aims to evaluate and compare the clinical effectiveness of antimicrobial photodynamic therapy (aPDT) using toluidine blue O (TBO) activated by two different diode laser wavelengths as an adjunct to non-surgical…
- Trial name
- NCT07849647
- Testing
- 635 nm Diode Laser-Mediated aPDT + Non-Surgical Periodontal Treatment, 810 nm Diode Laser-Mediated aPDT + Non-Surgical Periodontal Treatment, Non-Surgical Periodontal Treatment Alone (Control)
- Where
- Syria
- Volunteers
- 12 people
- Sponsor
- Damascus University
Periodontal Diseases, Periodontal Attachment Loss
Clinical Effectiveness of Biologic Agents as an Adjunct to Non-surgical Periodontal Therapy of Intrabony Defects
The aim of the present study is to clinically and radiographically compare the efficacy of recombinant human platelet-derived growth factor (rhPDGF), Leukocyte-Platelet Rich Fibrin (L-PRF) and Enamel Matrix Derivatives (EMD) in…
- Conditions
- Periodontal Diseases, Periodontal Attachment Loss, Pocket, Periodontal, Intrabony Periodontal Defect
- Trial name
- NCT05858411
- Testing
- SRP+rhPDGF, SRP+L-PRF, MINST alone
- Where
- Albania
- Volunteers
- 88 people
- Sponsor
- G. d'Annunzio University
Gingival Health, Metal Ceramic Restorations
The Effect of Fixed Dentures on Periodontal Tissues in Long-term.
The goal of this observational study is to to evaluate the periodontal condition around metal-ceramic crown. The main question to be answered is: whether the metal-ceramic crown is the cause of gum changes? The study offers to…
- Trial name
- NCT07611461
- Where
- Latvia
- Volunteers
- 75 people
- Sponsor
- Riga Stradins University
Periodontal Disease, Periodontal Pockets
Adjunctive Diode Laser Therapy in Non-Surgical Periodontal Therapy
The goal of this clinical trial is to evaluate the efficacy of adjunctive application of diode laser to mechanical, non-surgical root surface debridement in patients attending periodontal office.
- Conditions
- Periodontal Disease, Periodontal Pockets, Periodontal Attachment Loss
- Trial name
- NCT07446127
- Testing
- LASER assisted SRP, RsD
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Tel Aviv University
Periodontitis, Periodontitis (Stage 3)
Periodontal Dressings in Non-Surgical Therapy
This study aims to evaluate and compare the efficacy of two different eugenol-free periodontal dressing materials-Ora-Aid (a hydrophilic polymer) and Coe-Pak (a zinc oxide-based paste)-following non-surgical periodontal treatment…
- Conditions
- Periodontitis, Periodontitis (Stage 3), Periodontal Pocket
- Trial name
- NCT07472218
- Testing
- Ora Aid application, Coe-Pack application
- Volunteers
- 25 people
- Sponsor
- Saglik Bilimleri Universitesi
Periodontal Pocket
Ozonized Olive Oil in the Treatment of Periodontal Pockets
A randomized controlled clinical trial was conducted on 16 patients (8 males and 8 women) who were diagnosed chronic periodontitis.
- Trial name
- NCT06980675
- Testing
- Activated Ozonized Olive Oil Gel
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari
Periodontitis, Pocket, Periodontal
Adjunctive Effect of Erythritol on Pocket Closure Rates
This clinical trial is studying whether using erythritol powder during non-surgical periodontal treatment (deep cleaning) helps improve gum health in people with severe periodontitis.
- Conditions
- Periodontitis, Pocket, Periodontal, Pocket, Gingival
- Trial name
- NCT06958874
- Testing
- Non-surgical periodontal therapy + sub-gingival air polishing, Non-surgical periodontal therapy alone
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- University of L'Aquila
Periodontitis, Periodontal Pocket
Modified Widman Flap vs Fibre Retention Osseous Resective Surgery
The treatment of periodontitis should be carried out in an incremental manner, first by achieving adequate patient's oral hygiene practices and risk factor control during the first step of therapy and then, during the second step…
- Conditions
- Periodontitis, Periodontal Pocket, Periodontal Attachment Loss
- Trial name
- NCT06123000
- Testing
- Modified Widman Flap (MWF), Fiber Retention Osseous Resective Surgery (FibReORS)
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Florence
Chronic Periodontitis
Clinical and Radiographic Evaluation of Doxycycline and Atorvastatin Loaded Chitosan Nanoparticles as an Adjunctive to Scaling and Root Planning in the Management of Chronic Periodontitis. A Randomized Controlled Clinical Trial.
Chronic periodontitis is one of the most prevalent inflammatory diseases affecting the tooth-supporting structures and is characterized by progressive clinical attachment loss and alveolar bone resorption resulting from a complex…
- Trial name
- NCT07634341
- Testing
- Doxycycline and Atorvastatin loaded Chitosan nanoparticles local drug
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Fayoum University