Clinical trials: Periodontal Pocket, active
Peri-Implantitis
Management of Peri-implantitis: Non-surgical Treatment of Peri-implantitis.
The goal of this clinical trial is to compare non-surgical treatment by mechanical debridement with air-polishing in peri-implantitis.
- Trial name
- NCT05683405
- Testing
- Non-surgical treatment of peri-implantitis with mechanical debridement, Non-surgical treatment of peri-implantitis with air polishing
- Where
- Norway
- Volunteers
- 88 people
- Sponsor
- Tannhelsetjenestens Kompetansesenter for Nord-Norge
Periodontitis, Pocket, Periodontal
Diode Laser as an Adjunct to Professional Mechanical Plaque Removal
This study will utilize diode laser to determine its effects on improving periodontal parameters and inflammatory biomarkers, comparing with conventional treatment alone, and evaluate its effectiveness in improving periodontal…
- Trial name
- NCT06719674
- Testing
- Professional mechanical plaque removal and Laser, Professional mechanical plaque removal
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- University of Sulaimani
Periodontitis, Periodontal Diseases
NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration
Three techniques for periodontal reconstruction will be compared, in which marginal access versus apical access will be carried out.
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket
- Trial name
- NCT03997552
- Testing
- Non-incised papillae surgical approach (NIPSA), marginal approach by palatal incision, Minimally invasive surgical technique (MIST)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Murcia
Third Molar Impaction, Surgical Extraction of Impacted Third Molars
The Effect of Platelet Rich Fibrin On Sensitivity and Periodontal Pockets Distal to Second Molar After Surgical Extraction of Impacted Third Molar
Surgical extraction of impacted third molar is the most common surgical procedure performed in oral and maxillofacial surgery. The immediate post operative complications after 3rd molar surgery are pain, swelling and trismus…
- Trial name
- NCT07351279
- Testing
- Platelet rich fibrin
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- University of Health Sciences Lahore
Periodontitis
Injectable Platelet Rich Fibrin in Periodontal Treatment
The aim of this randomized controlled parallel clinical trial is to investigate the efficacy of injectable Platelet Rich Fibrin (iPRF) as an adjunctive to non-surgical periodontal therapy (STEP 1 \& 2 of periodontal treatment).
- Trial name
- I-PRF (NCT06814418)
- Testing
- Non-surgical periodontal treatment, Injectable Platelet Rich Fibrin (I-PRF)
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- Aristotle University Of Thessaloniki
Periodontitis
Non-Surgical Treatment of Periodontitis With Adjunctive Sodium Hypochlorite/Amino Acids and Cross-Linked Hyaluronic Acid
The goal of this clinical trial is to learn if using sodium hypochlorite/amino acid gel, with or without cross-linked hyaluronic acid, as an addition to standard non-surgical periodontal therapy works to treat periodontitis in…
- Trial name
- NCT07474272
- Testing
- Standard Non-Surgical Periodontal Therapy, tandard Therapy + Sodium Hypochlorite/Amino Acid Gel, Standard Therapy + Sodium Hypochlorite/Amino Acid Gel + Cross-Linked Hyaluronic Acid
- Where
- Lebanon
- Volunteers
- 78 people
- Sponsor
- Marwan El Mobadder
Periodontal Diseases, Periodontal Pocket
Occlusal Load Distribution and Periodontal Status
Occlusal forces are unevenly distributed among teeth during mastication, potentially predisposing certain teeth to higher functional loads.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Periimplantitis
- Trial name
- Perio-Occlusio (NCT07199062)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Periodontitis, Periodontitis and Treatment Need
Dental Loupe Versus Dental Operating Microscope for Non-Surgical Periodontal Treatment
Periodontitis is a multifactorial, non-infectious disease that can lead to tooth loss if left untreated. Advanced stages of periodontitis can affect chewing ability, nutritional status, and quality of life.
- Conditions
- Periodontitis, Periodontitis and Treatment Need, Periodontal Disease, Periodontal Pocket
- Trial name
- NCT07822269
- Testing
- Mechanical debridement and dental plaque sample collection with dental loupe, Mechanical debridement and dental plaque sample collection with dental microscope
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Periodontitis
Granulation Tissue From Residual Periodontal Pockets
This observational study aims to describe the histopathological features of granulation tissue (GT) found in residual periodontal pockets at the time of surgical intervention, after completion of the first two steps of…
- Trial name
- GTRP (NCT07587606)
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- University of Roma La Sapienza
Periodontitis, Periodontal Pocket
Comparing Different Timings for Periodontal Re-evaluation After Non-surgical Periodontal Therapy (NSPT)
This is a prospective cohort study that aims to describe the difference in terms of percentage of closed pockets (PPD <5 mm and no BOP) when performing the periodontal re-evaluation at 3-4, 6-8 and 12 months.
- Trial name
- NCT05088746
- Testing
- Non-surgical periodontal therapy
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Parma
Infra-bony Periodontal Defect
Effect of Gingival Mesenchymal Stem Cell-Derived Small Extracellular Vesicles in Management of Infra-bony Periodontal Defect
The goal of the study to evaluate whether the adjunctive use of gingival mesenchymal stem cell-derived extracellular vesicles (GMSC-derived EVs) combined with β-tricalcium phosphate (β-TCP) and a collagen membrane results in…
- Trial name
- NCT07867067
- Testing
- Gingival mesenchymal stem cell derived small extracellular vesicles, β-calcium triphosphate (β-TCP) + collagen membrane
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Ain Shams University
Periodontal Diseases, Periodontal Pocket
Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization
This study is being performed to compare different methods of visualization during routine gum surgery. The gum surgery is standard of care.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Periodontal Inflammation
- Trial name
- NCT05932017
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Bone Loss, Pocket, Periodontal
Influence of Acetal Resin Versus Nylon Elastic Cap on Crestal Bone Loss in Mandibular Implant-Supported Overdenture
Objective: To evaluate and compare the effect of two different attachment housing materials-Acetal Resin (Polyoxymethylene) versus conventional Nylon elastic caps-on marginal crestal bone loss around dental implants supporting a…
- Trial name
- AcetalResin (NCT07666763)
- Testing
- Acetal Resin, nylon
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Periodontal Diseases, Gingival Diseases
Novel Dental Gel as an Adjunct to Scaling and Root Planing
This study will evaluate the use of Livionex Dental Gel (LDG) as a home care product in reducing probing pocket depth (PD) beyond the effect achieved by the current standard of care with SRP in periodontitis patients.
- Conditions
- Periodontal Diseases, Gingival Diseases, Gingival Pocket, Gum Bleed
- Trial name
- NCT05384132
- Testing
- SRP + Livfresh Dental Gel, SRP + standard flouride dentifrice
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Periodontitis
Diode Laser 635 nm and 810 nm Photodynamic Therapy as Adjuncts to Non-Surgical Periodontal Treatment
This study aims to evaluate and compare the clinical effectiveness of antimicrobial photodynamic therapy (aPDT) using toluidine blue O (TBO) activated by two different diode laser wavelengths as an adjunct to non-surgical…
- Trial name
- NCT07849647
- Testing
- 635 nm Diode Laser-Mediated aPDT + Non-Surgical Periodontal Treatment, 810 nm Diode Laser-Mediated aPDT + Non-Surgical Periodontal Treatment, Non-Surgical Periodontal Treatment Alone (Control)
- Where
- Syria
- Volunteers
- 12 people
- Sponsor
- Damascus University
Periodontal Pocket
The Proposed Study Aims to Investigate the Efficacy of Quercetin as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis
the proposed study aims to investigate the effect of Quercetin in treatment of periodontitis patients
- Trial name
- NCT06982248
- Testing
- NSP and chitosan nanoparticles gel loaded by quercetin, NSP and chitosan nanoparticles gel, scaling and root planning
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Periodontology, Periodontal Disease
Evaluation of Hyaluronic Acid and Chlorhexidine Gel as an Adjunct to Minimally Invasive Non-surgical Therapy in the Treatment of Stage III and IV Periodontitis
Stage III and IV periodontitis are advanced forms of periodontal disease characterized by significant attachment loss, deep periodontal pockets, and progressive destruction of supporting periodontal tissues.
- Conditions
- Periodontology, Periodontal Disease, Periodontal Diseases, Periodontitis (Stage 3)
- Trial name
- NCT07731113
- Testing
- MINST + CHX+HA gel, MINST
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Periodontal Diseases, Periodontal Attachment Loss
Clinical Effectiveness of Biologic Agents as an Adjunct to Non-surgical Periodontal Therapy of Intrabony Defects
The aim of the present study is to clinically and radiographically compare the efficacy of recombinant human platelet-derived growth factor (rhPDGF), Leukocyte-Platelet Rich Fibrin (L-PRF) and Enamel Matrix Derivatives (EMD) in…
- Conditions
- Periodontal Diseases, Periodontal Attachment Loss, Pocket, Periodontal, Intrabony Periodontal Defect
- Trial name
- NCT05858411
- Testing
- SRP+rhPDGF, SRP+L-PRF, MINST alone
- Where
- Albania
- Volunteers
- 88 people
- Sponsor
- G. d'Annunzio University
Gingival Health, Metal Ceramic Restorations
The Effect of Fixed Dentures on Periodontal Tissues in Long-term.
The goal of this observational study is to to evaluate the periodontal condition around metal-ceramic crown. The main question to be answered is: whether the metal-ceramic crown is the cause of gum changes? The study offers to…
- Trial name
- NCT07611461
- Where
- Latvia
- Volunteers
- 75 people
- Sponsor
- Riga Stradins University
Periodontal Disease, Periodontal Pockets
Adjunctive Diode Laser Therapy in Non-Surgical Periodontal Therapy
The goal of this clinical trial is to evaluate the efficacy of adjunctive application of diode laser to mechanical, non-surgical root surface debridement in patients attending periodontal office.
- Conditions
- Periodontal Disease, Periodontal Pockets, Periodontal Attachment Loss
- Trial name
- NCT07446127
- Testing
- LASER assisted SRP, RsD
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Tel Aviv University