Clinical trials: Perioperative Monitoring
Perioperative Neurocognitive Disorders
The Reliability and Validity of Perioperative Cognitive Test Network Platform for Monitoring Neurocognitive Changes
This study aimed to analyze the reliability and validity of the results of the new designed perioperative cognitive test network platform, and to judge the reliability and scientific nature of the perioperative cognitive test.
- Trial name
- NCT06028568
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Regional Anesthesia, Pain
Nociception Index Level (NOL) Perioperative Monitoring During Regional Anesthesia
This prospective observational study was conducted to assess pain using NOL index under locoregional anesthesia for orthopedic surgery of the upper limb.
- Conditions
- Regional Anesthesia, Pain, Intraoperative Monitoring
- Trial name
- NOL and LRA (NCT06300606)
- Testing
- NOL monitoring
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- American Hospital of Paris
Polyneuropathies
Diagnostic Feasibility of 100 Hz Tetanic Stimulation
The goal of this observational study is to investigate the applicability of 100 Hz tetanic stimulation with an electromyography device in the exclusion of postoperative residual neuromuscular block.
- Trial name
- NCT06754995
- Where
- 2 sites in Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Debrecen
Diabetes Mellitus, Hypoglycemia
Perioperative Hypoglycemia in Diabetic Patients Undergoing Vitrectomy: a Masked CGM Prospective Observational Study
Patients with diabetes are at increased risk of perioperative glycemic disturbances due to preoperative fasting, the surgical stress response, and the use of insulin or oral hypoglycemic agents.
- Trial name
- NCT07696910
- Testing
- Masked continuous glucose monitoring (FreeStyle Libre 2®)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary)
Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy
This study will evaluate whether quantitative pupillometry measurements can be used to identify children at risk for postoperative opioid-induced respiratory depression (OIRD) following tonsillectomy.
- Conditions
- Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
- Trial name
- NCT07573150
- Testing
- Infrared Pupillometry
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- NeurOptics Inc
ADHD - Attention Deficit Disorder With Hyperactivity
Clinical Study of Non-invasive 40-Hz Audiovisual Stimulation Guided by Gamma EEG Monitoring for Promoting Perioperative Brain Function Recovery in Children
Exposure to general anesthesia during early brain development has emerged as an important risk factor for long-term attention-deficit/hyperactivity disorder (ADHD)-like behaviors and learning difficulties in school-aged children.
- Trial name
- NCT07719465
- Testing
- 40-Hz non-invasive synchronized audiovisual stimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Constipation, Perioperative Nursing
Effect of a Constipation Prevention Checklist in Hip Surgery Patients
Constipation is a common postoperative problem in patients undergoing hip surgery and may be associated with immobilization, opioid analgesic use, and inadequate fluid and fiber intake.
- Conditions
- Constipation, Perioperative Nursing, Checklist, Orthopedic Disorder
- Trial name
- NCT07895316
- Testing
- Constipation prevention and checklist monitoring in hip surgery patients
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Pain, Postoperative
Wearable Electrocardiogram Monitoring Device and Smartphone Application in Perioperative Pain Management
This study aims to develop a wearable electrocardiograph monitoring device and smartphone application in perioperative pain management, also to evaluate relationship between postoperative pain and heart rate variability.
- Trial name
- NCT04686526
- Where
- China
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Anesthesia, Neuromuscular Blockade
International Focus Group Discussion on Neuromuscular Monitoring.
Focus-Group based discussion designed to gain more in-depth information on factors that could lead to an increase in the adoption of neuromuscular monitoring taking into account different country-specific contexts.
- Conditions
- Anesthesia, Neuromuscular Blockade, Neuromuscular Block, Residual, Perioperative/Postoperative Complications
- Trial name
- NCT06945341
- Testing
- Focus-Group discussion
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Emergence Delirium in Pediatric Anesthesia, Perioperative Ketonemia and Its Association With Recovery Outcomes in Children
"KETOMED: Ketonemia and Risk of Emergence Delirium in Children Undergoing General Anesthesia - A Multicenter Observational Study"
The objective of this observational study is to evaluate the relationship between ketonemia and emergence delirium in children undergoing general anesthesia.
- Trial name
- KETOMED (NCT07249736)
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital Clínico Universitario de Valladolid
Surgical Site Infections, Stress Hyperglycemia
Perioperative Glucose Monitoring and Treatment to Reduce Risk of Surgical Site Infections and Complications
This study is to determine if glucose monitoring and treatment in surgical procedures over 2 hours help to decrease the surgical site infection risk and reduce postoperative complications.
- Trial name
- POGM (NCT06765655)
- Testing
- Insulin Lispro Injection, glucose testing
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- St. Peter's Hospital, Albany, NY
Coronary Artery Bypass Grafting, Cardiopulmonary Bypass
Relationship Between Perioperative Carotid Blood Flow Monitoring and Cerebral Function Protection in Cardiac Surgery
Postoperative cognitive dysfunction (POCD) is a common complication of cardiac surgery, mainly manifested as mental confusion, anxiety, personality change and memory impairment, which seriously affects the quality of life of…
- Trial name
- NCT05586347
- Testing
- Nicardipine, normal saline
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Pain Management, Postoperative Pain
Effects of S-ketamine on Perioperative Opioid Consumption
This study is a triple-blind randomized controlled trial conducted at a tertiary care hospital in Brussels. It investigates whether a single dose of S-ketamine can reduce opioid (morphine) consumption in the first 24 hours after…
- Conditions
- Pain Management, Postoperative Pain, Opioid Consumption, Postoperative, Opioid Analgesia
- Trial name
- NCT07528651
- Testing
- Esketamine at low dose, Saline (0.9% NaCl)
- Where
- Belgium
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Pancreatic Neoplasms, Adenocarcinoma
Perioperative Cancer Cell Dissemination and Systemic Immune Suppression in Resectable Ductal Pancreatic Adenocarcinoma
The purpose of this study is to determine whether early recurrence after curative resection of ductal pancreatic adenocarcinoma can be explained by either dissemination of cancer cells during intraoperative tumour manipulation…
- Conditions
- Pancreatic Neoplasms, Adenocarcinoma, Neoplasm Circulating Cells, Tumor Markers, Biological
- Trial name
- NCT00495924
- Testing
- Pancreatic resection (PD)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Endothelial Dysfunction
Clinical Monitoring of Endothelial Dysfunction for Pregnant Women and in the Perioperative Course
A single- center prospective observational study. This study evaluates different aspects of endothelial function. It investigates the endothelial leakage with the venous occlusion plethysmography and the flow-mediated…
- Trial name
- NCT01311297
- Where
- Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Claudia Spies
Pre-Eclampsia
Utilization of Somatic Tissue Oxygen Saturation Monitoring in Pregnant Women
The purpose of this study is to compare 3 methods of assessing endothelial function in healthy female volunteers and pregnant women with and without pregnancy induced hypertension.
- Trial name
- NCT03196141
- Testing
- StO2 and EndoPAT
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Perioperative Care, Fluid Therapy
Paired Comparison of SVV and PVI Accuracy
This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a…
- Conditions
- Perioperative Care, Fluid Therapy, Monitoring, Physiologic, Hemodynamics
- Trial name
- NCT07260890
- Testing
- Stroke Volume Variation (SVV) monitoring, Pleth Variability Index (PVI) monitoring
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Anesthesia, Pain
Association of Perioperative Electroencephalography Spectral Analysis With Postoperative Complications
Using data from electroencephalogram (EEG) obtained through intraoperative depth of anesthesia monitoring devices, combined with clinical symptoms such as postoperative pain and delirium, investigate their correlation and verify…
- Conditions
- Anesthesia, Pain, EEG
- Trial name
- NCT05818163
- Testing
- electroencephalography spectral analysis
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Neuromuscular Blockade Reversal Agent, Perioperative Complications
Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal
Study Objective: This study aims to evaluate the incidence, severity, and risk factors of sugammadex-induced mouth clenching during neuromuscular blockade (NMB) reversal in adult surgical patients.
- Conditions
- Neuromuscular Blockade Reversal Agent, Perioperative Complications, Anesthesia, General, Sugammadex
- Trial name
- NCT06962007
- Testing
- Sugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group
- Where
- South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Bleeding, Hemorrhage
The Effect of Non-invasive Hemoglobin Measurement in Hip Surgeries
Bleeding is one of the most important causes of mortality and morbidity in patients. Hb levels are the most prevalently utilized monitoring parameter in hemorrhagic patients in the hemodynamic sense.
- Conditions
- Bleeding, Hemorrhage, Hemodynamic Instability
- Trial name
- NCT04785274
- Testing
- non-invasive hemoglobin (SpHb)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University