Clinical trials: Periorbital
Laser, Periorbital
Efficacy of Periorbital Rejuvenation With a 1927 nm Diode Laser Treatment
The purpose of this research project is to investigate the treatment design, therapeutic effects and safety of the 1927 nm laser for the rejuvenation of the skin around the eyes.
- Trial name
- NCT05811026
- Testing
- Periorbital rejuvenation with a 1927 nm diode laser treatment (2-week interval), Periorbital rejuvenation with a 1927 nm diode laser treatment (4-week interval)
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Nausea, Vomiting
Periorbital Massage for Nausea and Vomiting After Laparoscopic Surgery
Laparoscopic cholecystectomy is one of the commonly used surgical treatment methods for gallbladder diseases. However, many patients experience significant nausea and vomiting after laparoscopic cholecystectomy.
- Conditions
- Nausea, Vomiting, Laparoscopic Cholecystectomy
- Trial name
- NCT06954935
- Testing
- periorbital massage
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Atlas University
Wrinkles
Argireline in Treatment of Periorbital Wrinkles
The purpose of this study is to determine whether La Jolie gel is effective in the treatment of periorbital wrinkles.
- Trial name
- NCT01381484
- Testing
- 10% Argireline
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Wrinkle
A Prospective, Single Center, Single-Arm Clinical Study of 20 Participants to Reduce the Appearance of the Peri-orbital Wrinkles. Participants Will Receive up to Four Treatments With Tixel Every 4 Weeks. Follow-up Will Occur 1 Month and 3 Months Following Last Treatment.
A Prospective, Single center, Single-Arm Clinical Study of 13-20 study participants who are seeking a procedure to reduce the appearance of the peri-orbital wrinkles.
- Trial name
- NCT05282979
- Testing
- Tixel 2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Physicians Laser and Dermatology Institute
Glabellar Lines, Midface Volume Deficiency
Prospective, Non-interventional Study Assessing Periorbital Rejuvenation Procedure
The goal of this observation is to assess the time course of holistic extended periorbital rejuvenation using botulinum toxin A, cross-linked hyaluronic acid and polynucleotides corresponding to the application in routine…
- Conditions
- Glabellar Lines, Midface Volume Deficiency, Periorbital Wrinkling
- Trial name
- NCT07398755
- Testing
- Letybo®, Philart® Eye, Saypha® Volume Plus Lidocaine
- Where
- Austria
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yuvell
Periorbital Hyperpigmentation
Physiopathologic Aspects and Quality of Life in Participants With Eye Dark Circles
This study will evaluate the physiopathologic characteristics of dark circles in participants with various ethnicities and Fitzpatrick Skin Types and the impact of the dark circles on the quality of life.
- Trial name
- NCT03400202
- Testing
- Skin imaging, Facial cleanser
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Allergan
Periorbital Area
A Clinical Trial to Evaluate the Effects of an Eye Serum on Improving the Appearance of the Periorbital Area
This study will evaluate the efficacy of the DIME Beauty Luminosity Eye Serum in improving the appearance of skin in the periorbital eye area. This study will last for 60 days.
- Trial name
- NCT06143033
- Testing
- DIME Beauty Luminosity Eye Serum
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dime Beauty Co.
Investigating the Effects of Periocular Acupressure on Ocular Biological Indicators
Effects of Acupoint Massage Around Eyes on Ocular Biological Indexes
This study aims to investigate whether the acupoint eye exercise could impact the biological parameters of the eye.
- Trial name
- NCT06293196
- Testing
- acupressure
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Wrinkle
A Safety and Effectiveness Study of the Tixel Device, (Fractional Peri-orbital Wrinkles Treatment ) Compared With Laser
This study is designed to explore the safety and the effectiveness of the Tixel device. This device performs fractional treatment of the skin by applying thermal (heat) energy to the skin.
- Trial name
- NCT03454672
- Testing
- Tixel, Laser
- Where
- 2 sites in United States, Israel
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Novoxel Ltd.
Wrinkles
Fractional Laser vs. Ultrasound for Periorbital Wrinkles
The primary objective of this study is to compare the efficacy of intense focused ultrasound and carbon dioxide-fractionated laser for treatment of periorbital wrinkles.
- Trial name
- NCT01529983
- Testing
- Laser treatment, High-intensity focused ultrasound
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Wrinkles
Silk'n HST for Wrinkle Reduction - Clinical Study Protocol
The objective of the study is to evaluate the safety, efficacy and usage compliance of the home-use device Silk'n HST for self-treatment of periorbital wrinkles and skin laxity and improvement of skin appearance.
- Trial name
- NCT02913547
- Testing
- Silk'n HST
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Periorbital Wrinkles
Evaluation of the Safety and Performance of Epicare for the Treatment of Periorbital Wrinkles
This is a prospective, interventional, evaluator-blinded, multi-center clinical study designed to assess the safety and performance of the Epicare fractional nano-thulium (Tm:YAP 1938 nm) laser system for the treatment of…
- Trial name
- NCT07114562
- Testing
- Epicare
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laser team Ltd
Periorbital Hyperpigmentation, Periorbital Edema
A 12 Week Study to Evaluate the Efficacy of an Eye Cream
This single center, open-label clinical study was conducted to assess the efficacy and tolerance of a topical eye cream when used over the course of 12 weeks by healthy women with moderate to severe under-eye dark circles…
- Conditions
- Periorbital Hyperpigmentation, Periorbital Edema, Fine Lines, Wrinkle
- Trial name
- NCT05807620
- Testing
- Gentle Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 30
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Wrinkled Structure
A Confirmatory Study for Evaluation of the Treatment by the Celluma3 of Periorbital Wrinkles
The primary objective of this study is to confirm the safe and effective use of the Celluma3 for the reduction in the appearance of periorbital wrinkles.
- Trial name
- NCT02543970
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- BioPhotas
Wrinkle
Confirmatory Study: Assessing the Efficacy and Safety of the AcusMu Microneedle Patch in Treating Periorbital Wrinkles
The core objective of this study is to validate the safe and efficacious application of the AcusMu microneedle patch (FMD WK) to enhance the appearance of periorbital wrinkle
- Trial name
- NCT06158867
- Testing
- FMD WK
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AcusMu Medtech Co., Ltd.
Periorbital Wrinkles, Periorbital Area
Non-invasive Rejuvenation of the Periorbital Area and Lower Eyelid
The goal of this clinical trial is to determine the BTL-785-7-11 applicator effectiveness for an under-eye appearance improvement by evaluation of the periorbital area in healthy adult volunteers.
- Conditions
- Periorbital Wrinkles, Periorbital Area, Under-eyes Dark Circles, Crows Feet
- Trial name
- NCT07028203
- Testing
- Treatment with BTL-785 with the applicator BTL-785-7-11
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Mild to Moderate Temporal Atrophy, Moderate to Severe Glabellar Rhytids
Upper Facial Remodeling With Perlane-L and Dysport
The purpose of this study is to provide data to support combination treatment of the upper face with Perlane-L® and Dysport™. This study will assess the outcome of upper face rejuvenation in the temporal fossa; outcome of…
- Conditions
- Mild to Moderate Temporal Atrophy, Moderate to Severe Glabellar Rhytids, Moderate to Severe Periorbital Rhytids
- Trial name
- DPL-2010 (NCT01354743)
- Testing
- Dysport, Perlane L
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beer, Kenneth R., M.D., PA
Dark Eye Circles (Periorbital Hyperpigmentation)
Vitamin K2 (35) (MK-7) Reduces Dark Eye Circles: a Mechanistic and Human Efficacy Study
The goal of this clinical trial is to learn if an eye cream containing 0.05% Vitamin K2 (35) (MK-7) works to reduce vascular-type dark eye circles in women aged 20-60 years.
- Trial name
- NCT07881367
- Testing
- MK-7 Eye Cream
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nanjing Ascend Biotech Technology Co., Ltd.
Skin Laxity
Post-Market Lower Eyelid Treatment With Renuvion in Greece
This is a prospective, multi-center, non-randomized, single-arm study of up to 15 subjects treated with the Renuvion APR System.
- Trial name
- NCT05605691
- Testing
- Renuvion APR System
- Where
- Greece
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Apyx Medical
Facial Skin, Motion Capture
Research on the Evolution, Geometry, and Alterations of the Periorbital Region Based on Age and Deformations
The periorbital region of the face is a critical area affected by aging. Motion Capture (MoCap) allows the precise measurement of the mechanical properties of skin in this region.
- Conditions
- Facial Skin, Motion Capture, Aging, Periorbital Region
- Trial name
- REGARD (NCT07080320)
- Testing
- MoCap
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens