Clinical trials: Peripheral Blood Flow
Electromyographic Response to Blood Flow Restriction Exercise in Healthy Adults
Electromyographic Response to Blood Flow Restriction Exercise in Healthy Adults
This pilot randomized contralateral within-participant study evaluated the immediate neuromuscular response to low-load knee extension exercise performed with and without blood flow restriction in healthy young adults.
- Trial name
- NCT07654608
- Testing
- Bilateral low-load knee extension exercise protocol, Pneumatic blood flow restriction cuff
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Healthy Aortic Blood Flow
Quantifying Blood Flow in the Aorta
This study aims to gain insights into aortic blood flow in healthy volunteers using PC 4D-flow MRI
- Trial name
- AF-4DMRI-P2 (NCT07577752)
- Testing
- 4D-flow Magnetic Resonance Imaging, Questionnaires
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Twente
Sexual Dysfunction, Stress Incontinence
A Study to Measure the Degree and Effectiveness of the Various vSculpt Operating Modes
A pilot study to determine the degree and effectiveness of the various modes of vSculpt, an over-the-counter "OTC" medical device, on enhanced genital blood flow and improvement in quality of life in menopausal women who suffer…
- Trial name
- NCT02856490
- Testing
- vSculpt, InTone
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Joylux, Inc.
Kidney Diseases
The Effects of Glucagon on Renal Regional Blood Flow in Humans Measured by Magnetic Resonance.
This study will investigating the effects of glucagon on renal blood flow in humans using MRI technology. Glucagon, a hormone produced by the pancreas, plays a key role in regulating blood sugar levels.
- Trial name
- NCT06872060
- Testing
- Glucagon, Glucagon+Exendin9-39, Sodium chloride
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Pregnancy, Polycystic Ovary Syndrome
Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women
A more recent prospective nonrandomized placebo-controlled double-blind clinical study demonstrated that metformin exerts a slight but significant deleterious effect on serum homocysteine (Hcy) levels in patients with PCOS, and…
- Trial name
- NCT01115140
- Testing
- Metformin plus folic acid
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Cerebrovascular Circulation, Magnetic Resonance Imaging
Brain Blood Flow Responses During Exercise
Brain blood flow will be measured during exercise using magnetic resonance imaging.
- Trial name
- NCT05864950
- Testing
- MRI
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Aerobic Exercise, Blood Flow Restriction Therapy
Effects of Aerobic Blood Flow Restriction
The aim is to evaluate the effects of aerobic blood flow restriction on academy football players. Randomized clinical trial, with two intervention groups: Experimental group I will carry out training based on running on the…
- Trial name
- NCT06105697
- Testing
- Blood flow restriction Running on Treadmill, Running on Treadmill
- Where
- 2 sites in Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Normal, EEG
Exploratory Study on Artifact Denoising of Cerebral Blood Flow and EEG Data in Ambulance Settings
The purpose is to assess the extent of digital noise occurring during the measurement of cerebral blood flow and EEG in healthy adults within an ambulance setting and to explore the possibility of identifying and correcting…
- Conditions
- Normal, EEG, FNIRS
- Trial name
- NCT06701708
- Testing
- Participants are not assigned to interventions based on a protocol.
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Athletic Performance
Effects of Blood Flow Restriction and Small-Sided Games on Soccer Passing and Dribbling Stability Under Fatigue
This study aims to investigate whether applying blood flow restriction (BFR) during small-sided soccer games (SSG) can help soccer players maintain their passing and dribbling stability when they are fatigued.
- Trial name
- BFR-SSG (NCT07496944)
- Testing
- Blood Flow Restriction + Small-Sided Games (BFR-SSG), Small-Sided Games (SSG) Control
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Activity, Motor
Acute High Intensity Interval Training and Blood Flow Restriction
The study aims to look at the blood flow restriction (BFR) + high intensity interval training (HIIT) variables to induce an optimal acute training stimulus (i.e., acute responses in main outcome measures of muscular activation…
- Trial name
- NCT05835544
- Testing
- Active Comparator: HIIT Control, Experimental: HIIT + BFR between cycling sets, Experimental: HIIT + BFR moderate occlusion during cycling
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Osteoarthritis, Knee
Effects of Low Intensity Blood Flow Restriction on Clinical Outcomes in Women With Knee Osteoarthritis
Objective is to compare the effects of routine physical therapy with and without low intensity blood flow restriction on pain and quadriceps muscle strength in women with knee osteoarthritis.
- Trial name
- BFR (NCT04865692)
- Testing
- BFRT, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Hemodynamics of Cranial Arteries, Headache
The Hemodynamics Effect of Glibenclamide on Levcromakalim Assessed by High Resolution Magnetic Resonance Angiography (MRA) Technique in a Randomized Double-blind Cross-over Placebo-controlled Study With Healthy Volunteers
To investigate the effect of levcromakalim/placebo infusion on cranial arteries after glibenclamide administration.
- Conditions
- Hemodynamics of Cranial Arteries, Headache, Cerebral Blood Flow
- Trial name
- NCT03886922
- Testing
- Levcromakalim, Saline
- Where
- 2 sites in Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Postural Tachycardia Syndrome
Local Vasoconstriction in Postural Tachycardia Syndrome
The investigators study will determine how often blood flow regulation abnormalities and abnormalities of sympathetic regulation produced by nitric oxide, angiotensin-II, and oxidative stress occur in POTS and the mechanism(s) of…
- Trial name
- NCT01210430
- Testing
- Losartan, Ascorbic Acid (Vitamin C), Normal Saline
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- New York Medical College
Ocular Physiology, Retina
Is There a Difference in Flicker Induced Vasodilatation Between Smokers and Non-Smokers?
Habitual smoking is associated with an increased risk of coronary artery disease, cerebral and peripheral vascular disease, including ocular diseases like age-related macular degeneration or diabetic retinopathy.
- Conditions
- Ocular Physiology, Retina, Blood Flow Velocity
- Trial name
- NCT00431730
- Testing
- flicker light stimulation
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Multiple Sclerosis
Transcranial Electrical Stimulation in Multiple Sclerosis
First the investigators will examine if the blood flow in the brain is different in patients with Multiple Sclerosis compared to healthy volunteers. HOW? The blood flow of the subjects is imaged by use of a special MRI-technique.
- Trial name
- TEMS (NCT06966128)
- Testing
- transcranial Direct Current Stimulation
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Healthy
Effect of Smoking and Time of Day on Eosinophils
The study investigates the effect of acute smoking and time of day on blood eosinophils in chronic smokers. Chronic cigarette smokers without chronic respiratory diseases smoking at least 8 cigarettes per day and never-smoking…
- Trial name
- NCT07625111
- Testing
- Smoking for 4 hours
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marek Lommatzsch
Healthy
Effects of Miconazole on Blood Flow
This study will investigate the effect of the drug miconazole on blood vessel dilation. Miconazole stops production of EDHF, a substance that causes arteries to dilate. EDHF is produced by the cells that line blood vessels.
- Trial name
- NCT00004575
- Testing
- Miconazole, L-NMMA, Bradykinin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthy
Regulation of Optic Nerve Head Blood Flow During Combined Changes in Intraocular Pressure and Arterial Blood Pressure
Autoregulation is the ability of a vascular bed to maintain blood flow despite changes in perfusion pressure. The existence of an effective autoregulation in the optic nerve head (ONH) circulation has been shown in animals and…
- Trial name
- NCT00914992
- Testing
- Suction cup application, Squatting
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Blood Flow
Effect of AVACEN 100 on Brachial Artery Blood Flow
Determine effect of AVACEN 100 on brachial artery blood flow
- Trial name
- NCT04232111
- Testing
- Heat, Vacuum
- Volunteers
- healthy volunteers welcome
- Sponsor
- San Diego State University
Plyometric Exercise, Blood Flow Restriction Training
Effects of Ballistic Six Exercises With and Without Blood Flow Restriction in Cricket Players
Cricket is not only a widely played team sport, but it also involves intricate skills that are honed over time, especially in bowling.
- Trial name
- NCT06536777
- Testing
- Plyometric Exercises, Blood Flow Restriction Training
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University