Clinical trials: Peripheral Nerve Disorder
Peripheral Neuropathy
Effects of Light Emitting Diode Irradiation on the Conduction Parameters of the Superficial Radial Nerve
The introduction of light emitting diode (LED) devices as a novel treatment for pain relief in place of low-level laser warrants fundamental research on the effect of LED devices on one of the potential explanatory mechanisms…
- Trial name
- NCT01513148
- Testing
- Superluminous light diode
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Shenandoah University
Carpal Tunnel Syndrome
Non-surgical Treatment of Carpal Tunnel Syndrome: Night Splint Versus Local Corticosteroid Infiltration
Carpal tunnel syndrome (CTS) is the most common neuropathic compression syndrome of the upper limbs, caused by compression of the median nerve in the wrist. There is no gold standard for establishing the diagnosis of STC.
- Trial name
- NCT03196817
- Testing
- betamethasone dipropionate, betamethasone disodium phosphate and lidocaine 2%, Wrist splinting
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital Alvorada
or Peripheral Nerve Injury (PNI), Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN)
Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch
The Summary of product characteristics (SmPC) for QUTENZA advises that topical anaesthetic is applied prior to the application of QUTENZA.
- Trial name
- LIFT (NCT01416116)
- Testing
- QUTENZA, Lidocaine, Tramadol
- Where
- 20 sites in Belgium, Czechia and 5 more
- Volunteers
- 122 people
- Sponsor
- Astellas Pharma Inc
Wrist Injuries, Carpal Tunnel Syndrome
Effects of Pain Neuroscience Education and Standard Rehabilitation Regime in Patients of Carpal Tunnel Syndrome
The aim of this study is to check the effects of Pain Neuroscience education and standard rehabilitation regime in patients of carpal tunnel syndrome.
- Trial name
- NCT06509633
- Testing
- Pain Neuroscience education and standard rehabilitation regime, standard Rehabilitation regime
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Diabetic Polyneuropathy
A Study of CGRP Monoclonal Antibody to Treat Diabetic Neuropathy
The main purpose of this study is to compare the change in pain intensity during treatment with a CGRP monoclonal antibody (eptinezumab) compared with placebo treatment in patients with painful diabetic polyneuropathy (DPN).
- Trial name
- NCT05937152
- Testing
- Eptinezumab
- Where
- 3 sites in United States, Denmark
- Sponsor
- Mayo Clinic
Chemotherapy-induced Peripheral Neuropathy, Nerve Pain
The Effect of Yoga on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy)
The purpose of this study is to test whether yoga can reduce nerve pain caused by cancer treatment (chemotherapy-induced peripheral neuropathy, or CIPN).
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Nerve Pain, Neuropathy, Neuropathy, Painful
- Trial name
- YCT (NCT05121558)
- Testing
- Yoga, Education control, Usual care
- Where
- 8 sites in United States
- Volunteers
- 227 people
- Sponsor
- Dana-Farber Cancer Institute
Cervical Radiculopathy
Effects of Thoracic Screw Manipulation in Patients With Cervical Radiculopathy
Cervical radiculopathy is a pain and/or sensorimotor deficit syndrome that is defined as being caused by compression of a cervical nerve root.
- Trial name
- NCT05749835
- Testing
- Thoracic Manipulation and Sustained Natural Apophyseal Glides and conventional therapy, Sustained Natural Apophyseal Glides and conventional therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Diabetic Polyneuropathy, Diabetes Mellitus, Type 2
Driving with Neuropathy
This study is a proof-of-concept randomised controlled trial (RCT). The goal of the study is to investigate the effectiveness of a feedback intervention to improve use of the accelerator pedal in patients driving with diabetes…
- Trial name
- NCT06739135
- Testing
- Visual feedback training
- Where
- United Kingdom
- Volunteers
- 115 people
- Sponsor
- Manchester Metropolitan University
Cancer Pain, Chronic Pain
Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain
This Registry study will prospectively evaluate the differences in treatment outcomes in terms of pain intensity, pain interference, concomitant medication use, health-related quality of life, opioid adverse effects, and…
- Conditions
- Cancer Pain, Chronic Pain, Cancer Associated Pain, Neuropathic Pain
- Trial name
- NCT05674240
- Testing
- Intrathecal Targeted Drug Delivery, Conservative medical management
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Guillain-Barré Syndrome, Miller Fisher Syndrome
International Guillain-Barré Syndrome Outcome Study
International GBS Outcome Study (IGOS) is a study conducted by the members of the Inflammatory Neuropathy Consortium (INC) and Peripheral Nerve Society (PNS) on disease course and outcome in Guillain-Barré syndrome (GBS).
- Trial name
- IGOS (NCT01582763)
- Where
- 138 sites in United States, Argentina and 19 more
- Volunteers
- 2,000 people
- Sponsor
- Erasmus Medical Center
Charcot-Marie-Tooth Disease
A Study to Assess the Safety and Effectiveness of FLX-787 in Subjects With Charcot-Marie-Tooth Disease Experiencing Muscle Cramps.
The COMMIT Study will assess the safety and effectiveness of FLX-787 in men and women with Charcot-Marie-Tooth disease (CMT) experiencing muscle cramps.
- Trial name
- COMMIT (NCT03254199)
- Testing
- FLX-787-ODT (orally disintegrating tablet)
- Where
- 20 sites in United States
- Volunteers
- 27 people
- Sponsor
- Flex Pharma, Inc.
Sleep Disorders, Sciatica
Intravascular Laser and Electroacupuncture for Sciatica With Insomnia: A Pilot Trial
Sciatica is a common condition worldwide, with prevalence rates ranging from 1.2% to 43%. Chronic sciatica is often associated with sleep disturbances, forming a bidirectional loop where persistent nociceptive input disrupts…
- Trial name
- NCT06755593
- Testing
- Electroacupuncture, Intravascular Low-Level Laser Therapy (ILIB)
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Le Hoang Minh Quan
Lumbar Radiculopathy
PNE With Therapeutic Exercises on Pain Intensity in Lumbar Radiculopathy
There is lack of structured pain neuroscience education in patients with lumber radiculopathy. Previously researches were done on pain neuroscience education before surgery of lumber radiculopathy.
- Trial name
- NCT05356468
- Testing
- Structured pain neuroscience education, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Peripheral Arterial Occlusive Disease
Interest of a Bi-truncal Nerve Block (Femoral + Sciatic) Extended, Systematically Associated With General Anesthesia, in the Femoropopliteal Bypass: Study of Post-operative Analgesia and Peripheral Circulation Downstream
The aim of this study is to assess, in patients scheduled for femoropopliteal bypass, the benefit of a double peripheral nerve block (femoral + sciatic) with levobupivacaine and clonidine in a single dose, performed before…
- Trial name
- BLOC-FEMPOP (NCT01785693)
- Testing
- levobupivacaine, clonidine
- Where
- France
- Volunteers
- 47 people
- Sponsor
- University Hospital, Clermont-Ferrand
Scapula Alata, Scapular Winging
High Resolution Ultrasound of Scapulae Alatae - a Prospective Case Control Study
Scapula alata, caused by disturbance in the scapulothoracic stabilizer muscles due to nerve injury, is a relatively rare but also underreported disease.
- Trial name
- NCT03556449
- Testing
- High resolution ultrasound
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Sándor Beniczky
Sciatica
Effects of Pilates Exercises and Neural Dynamic Mobilization in Sciatica Patients
The main purpose of the study is to find the effects of Pilates exercises and neural mobilization techniques on pain, flexibility and quality of life in sciatica patients.
- Trial name
- NCT05959317
- Testing
- Pilates Exercises, Neural dynamic mobilization
- Where
- 2 sites in Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Stroke
Clinical Efficacy of Luna EMG Robot Therapy for Patients After Stroke
A lot of studies prove that rehabilitation with the use of modern devices accelerates the recovery of function in patients after stroke.
- Trial name
- NCT03888118
- Testing
- Luna EMG
- Volunteers
- 60 people
- Sponsor
- Rehamed Center
Carpal Tunnel Syndrome
Hydrodissection Between Normal Saline and a Combination of Triamcinolone Acetonide, Normal Saline, and Lidocaine in CTS
The goal of this randomized clinical trial is to compare the functional outcome of hydrodissection of the median nerve by normal saline only and a combination of triamcinolone acetonide, lidocaine, and normal saline.
- Trial name
- NCT05577676
- Testing
- Ultrasound-guided Hydrodissection of the Median Nerve
- Where
- Bangladesh
- Volunteers
- 62 people
- Sponsor
- Bangladesh College Of Physicians And Surgeons (BCPS)
Carpal Tunnel Syndrome, Hand Cyst Ganglion
Effectiveness of Audiovisual Versus Written Postoperative Instructions for Patients Undergoing Minor Hand Procedures
The utility and effectiveness of video-based instructions (VBI) versus standard written instructions was not previously investigated in hand surgery; thus, the objective of this study is to evaluate the effectiveness of…
- Conditions
- Carpal Tunnel Syndrome, Hand Cyst Ganglion, Trigger Finger
- Trial name
- NCT06582550
- Testing
- Minor Hand Procedure
- Volunteers
- 120 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Sciatica, Sciatica Due to Intervertebral Disc Disorder
Transforaminal Epidural Injection in Acute Sciatica
Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery.
- Conditions
- Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy
- Trial name
- TEIAS (NCT03924791)
- Testing
- Lidocaine, Methylprednisolone Acetate, Dexamethasone
- Where
- 2 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- C.L.A.Vleggeert-Lankamp
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.