Clinical trials: Physical Frailty
Sarcopenia, Muscle Atrophy
Vitamin D and Resistance Exercise Training; Effects on Musculoskeletal Health in Frail Older Men and Women
This study aims to determine whether vitamin D3 supplementation is any more effective in improving musculoskeletal function when combined with exercise training compared with exercise training alone.
- Conditions
- Sarcopenia, Muscle Atrophy, Osteoporosis
- Trial name
- EXVITD (NCT02467153)
- Testing
- RET, Vitamin D3
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Aging, Muscle Mass and Strength
One Year of Velocity-based Resistance Training in Older People Living in Nursing Homes
This study is an exercise intervention assessing the efficacy of a velocity-based resistance training (VBRT) in institutionalized older adults.
- Conditions
- Aging, Muscle Mass and Strength, Muscle Power, Frailty Syndrome
- Trial name
- NCT07027397
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Physical Inactivity, Frailty
The 'Outdoor Rehab-Fit' App-based Physical Activity Education Intervention for Frail Older Adults in Hong Kong
In recent years, research teams around the world have developed interventions to educate older adults to use outdoor exercise facilities (OEFs) to improve health outcomes like strength, balance, mobility, PA level, and weight.
- Trial name
- NCT06326710
- Testing
- mHealth, Health Talk
- Where
- Hong Kong
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Frail Elderly Syndrome, Fall
Relationship Between the Risk of Falls and Frailty, and the Effect of a Physical Exercise Program on These Conditions in the Elderly: a Randomized Crossover Clinical Trial.
The goal of this randomized crossover clinical trial is to examine the effectiveness of a new therapeutic exercise program in elderly patients with risk of falls and physical fragility.
- Trial name
- NCT05940779
- Testing
- Therapeutic exercise program
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Frailty, Disability Physical
Functional Decline and QoL in People Aging with HIV in Asia
This is a multi-center prospective cross-sectional study to determine the burden of decline in intrinsic capacity and functional ability, and the prevalence of geriatric syndromes, such as frailty, and disability in adult people…
- Conditions
- Frailty, Disability Physical, HIV/AIDS
- Trial name
- NCT04212884
- Where
- 2 sites in Hong Kong
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Frailty
Psychometric Properties of the Elderly Health Questionnaire Among Community-dwelling Older People
The aims of this study are to validate the reliability and validity of Elderly Health Questionnaire in assessing frailty risk of community-dwelling older adults.
- Trial name
- NCT04166123
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Frailty, Aging
Community-Based Multicomponent Exercise and Recreational Programme for Older Adults
This quasi-experimental, non-randomized controlled evaluation examined whether participation in ELDERPLAY, a community-based programme combining Vivifrail-based multicomponent exercise with adapted traditional games, was…
- Conditions
- Frailty, Aging, Physical Functional Performance, Postural Balance
- Trial name
- ELDERPLAY (NCT07864831)
- Testing
- ELDERPLAY multicomponent exercise and recreational programme
- Where
- Spain
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Physical Activity
Supervised Group-based Walking Intervention Among Inactive Older Adults in Saudi Arabia
The purpose of the proposed study is to compare the effects of supervised group-based walking and non-supervised individual-based walking interventions on frailty, cognitive function and quality of life among inactive older…
- Trial name
- NCT05151575
- Testing
- supervised group-based walking and non-supervised individual-based walking interventions
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Frailty
Exercise Program for Maintaining Physical Function and Frailty on Dwelling Older Adults
Older people living in their homes and receiving social assistance are at a high risk of suffering functional loss, hospitalization and/or developing disability. This condition is known as frailty.
- Trial name
- FragiCare (NCT05726214)
- Testing
- Exercise, Recommendations for active lifestyle
- Where
- Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Older Adults
The Effectiveness of Health Promotion Programs on the Pre-frail Individuals
This pilot study aimed to examine the efficacy of a home-based multicomponent exercise training program in older community- dwellers during to the Coronavirus Disease 2019.
- Trial name
- NCT05476471
- Testing
- multicomponent exercise training program
- Where
- Taiwan
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Shu-Hung Chang
Sarcopenic Obesity, Frailty
Multicomponent Analysis of phYsical Frailty BiomarkErs: Focus on Mitochondrial Health - MAYBE
The study will be conducted in a group of obese sarcopenic patients (Sarco-Ob) aged > 60 years on moderately hypocaloric diet therapy aimed at comparing the effect of a strength exercise protocol, combined or not with dietary…
- Conditions
- Sarcopenic Obesity, Frailty, Malnutrition; Protein
- Trial name
- MAYBE (NCT05938205)
- Testing
- AA-1, AA-2, Exe-H
- Where
- Italy
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Oral Health of Older Men
Talking Pen Audio-Interactive Program for Oral Frailty Delay in Community-Dwelling Elderly
This study aims to develop and evaluate the effectiveness of a talking pen audio-interactive technology integrated with an oral frailty delay care program for community-dwelling older adults in rural agricultural regions of…
- Trial name
- NCT07191600
- Testing
- Talking Pen Audio-Interactive Oral Frailty Care Program
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Fibromyalgia, Old Age; Debility
Frequency of Fibromyalgia Syndrome in Elderly Patients Aged 80 and Above and Its Relationship With Geriatric Parameters
The aim of this study was to determine the prevalence of fibromyalgia syndrome in patients aged 80 years and over and to examine the relationship between detailed geriatric assessment parameters and fibromyalgia syndrome.
- Trial name
- NCT06969716
- Testing
- Detailed geriatric assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Sultan 1. Murat State Hospital
Physical Activity, Elderly
Physical and Cognitive Exercises in Nursing Homes: Is Frailty Reversible?
Elderly in residential care spend 97% of their time sedentary. Moreover, exercise therapy often takes place in a poorly stimulating environment which is less motivational for the elderly to undertake regularly.
- Trial name
- NCT03526653
- Testing
- exercise without visual stimuli, excercise with National Geografics, Exercise with MemoRide
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Frailty Syndrome, Pre-frail Older Adults
Targeted Physical Function Exercises on Frailty and Falls Management in Pre-Frail Community-Dwelling Older Adults
The investigators will conduct a randomized controlled trial to assess the impact of targeted physical function exercises on frailty and falls in community-dwelling adults over 65 years of age.
- Trial name
- NCT06731712
- Testing
- Physical Function Exercises
- Where
- Greece
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Hellenic Mediterranean University
PROM, Satisfaction, Patient
Assessment of the Humanisation of Care in Hospitals in Andalusia-Spain
Observational assessment through patient interviews of relational, structural and organisational aspects related to the humanisation of health care.
- Conditions
- PROM, Satisfaction, Patient, Satisfaction, Personal, Stress
- Trial name
- HUMANCUIDA (NCT06174844)
- Testing
- No intervention applied
- Where
- Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Seville
Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults
The StayFitLonger Study: an Innovative Computerized Home-based Training to Foster Independent Life at Home
Multimodal training, including physical and cognitive activities, has been associated with a reduction in age-related physical and cognitive decline.
- Conditions
- Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults, Physical Decline Prevention in Robust Older Adults, Physical Decline Prevention in Pre-frail Older Adults
- Trial name
- SFL (NCT04237519)
- Testing
- SFL training, Active controlled training
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Sarcopenia
Multicomponent Intervention for Physical Frailty and Sarcopenia
The SPRINTT study will evaluate the efficacy of a multicomponent intervention programme (physical activity, nutritional counselling/dietary intervention, and information and communications technology intervention) compared with a…
- Trial name
- SPRINTT (NCT02582138)
- Testing
- Multicomponent intervention (MCI), Healthy Aging Lifestyle Education (HALE)
- Where
- Italy
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Sarcopenia, Aging
Effects of Polyphenol Supplementation and Exercise on Physical Performance in Older Adults
After approximately age 40 years, individuals experience a natural loss of muscle mass, strength, and physical function that is linked to higher risks of falls, disability, loss of independence, and mortality.
- Conditions
- Sarcopenia, Aging, Frailty
- Trial name
- NCT07441343
- Testing
- Polyphenol Rich-Extract, Resistance Band-Based & Aerobic Stationary Cycling Exercise
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. Chris McGlory, PhD
Frailty, Sarcopenia
Study of The Effects of Testosterone in Frail Elderly Men
The study aims to determine the effects of testosterone on muscle function, mobility, activities of daily living and overall quality of life
- Trial name
- NCT00190060
- Testing
- Transdermal testosterone gel (Testogel 1% )
- Where
- United Kingdom
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust