Clinical trials: Physical Frailty
Frailty, Morbidity, Multiple
Low-volume Cycling Training in Older People With Multimorbidity
INTRODUCTION: Physical exercise, when practiced regularly and in adequate doses, is a proven nonpharmacological measure that helps to prevent and reverse noncommunicable diseases, as well as reduce mortality rates from any cause.
- Trial name
- NCT04842396
- Testing
- Experimental:Motorized cycle ergometer
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidade da Coruña
Frail Elderly
Enhancing Physical Activity Levels of Frail Older People With a Wearable Activity Tracker-based Exercise Intervention
This study aims to investigate the feasibility, acceptability, and preliminary effects of a Wearable Activity Tracker (WAT)-based exercise intervention to increase physical activity levels in frail or pre-frail older people.
- Trial name
- NCT03538418
- Testing
- WAT
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Colon Cancer Patients Receiving Chemotherapy in the Adjuvant or Metastatic Setting, Aged 70 or Older
MOST: Mediterranean Oncology Senior Tests
MOST is a longitudinal study whose aim is to test the hypothesis that frailty markers are better at detecting vulnerable patients and that they are a better "Adverse Events" predictive tool than the CGA (Comprehensive Geriatric…
- Trial name
- MOST (NCT02148731)
- Testing
- Frailty markers
- Where
- 8 sites in France
- Volunteers
- 180 people
- Sponsor
- Association Sud pour la Recherche en Oncogériatrie
Aging, Muscle Mass and Strength
One Year of Velocity-based Resistance Training in Older People Living in Nursing Homes
This study is an exercise intervention assessing the efficacy of a velocity-based resistance training (VBRT) in institutionalized older adults.
- Conditions
- Aging, Muscle Mass and Strength, Muscle Power, Frailty Syndrome
- Trial name
- NCT07027397
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Sarcopenia, Physical Exercise
Physical Exercise, Nutrition Supplement and Frailty of Older Population
This study is aimed to explore the effect of physical exercise and nutrition supplement on improving frailty, depressive symptoms, and quality of life in community-dwelling older population.
- Conditions
- Sarcopenia, Physical Exercise, Nutrition Poor, Elderly
- Trial name
- NCT04777279
- Testing
- individual physical exercise group, individual Branched-Chain Amino Acids supplements group, combination of physical exercise and nutrition supplements group
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University
Sarcopenia, Muscle Atrophy
Vitamin D and Resistance Exercise Training; Effects on Musculoskeletal Health in Frail Older Men and Women
This study aims to determine whether vitamin D3 supplementation is any more effective in improving musculoskeletal function when combined with exercise training compared with exercise training alone.
- Conditions
- Sarcopenia, Muscle Atrophy, Osteoporosis
- Trial name
- EXVITD (NCT02467153)
- Testing
- RET, Vitamin D3
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Frailty, Weakness, Muscle
Precision Medicine and Physical Function
The investigators aim to conduct a 12-week, single-arm, pre/post-intervention of b-hydroxy-methylbutyrate in persons aged 65 to 85 years to assess feasibility and acceptability of the intervention and study procedures, secondary…
- Conditions
- Frailty, Weakness, Muscle, Multiple Chronic Conditions
- Trial name
- HMB (NCT05877846)
- Testing
- Beta-hydroxymethyl butyrate supplement, Vitamin D supplement, Matching Beta-hydroxymethyl butyrate supplement without Vitamin D
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Impaired Cognition, Quality of Life
The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery
The primary aim of this study is to establish if it is possible for patients who have undergone major body surgery to complete a home based exercise training program and complete the assessments required to measure physical and…
- Conditions
- Impaired Cognition, Quality of Life, Surgery, Delirium
- Trial name
- POETold (NCT03064308)
- Testing
- Exercise Programme
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- University of Nottingham
Frail Elderly Syndrome
Protocol of Geriatric Rehabilitation in Patients of 60 and Older Who Live in Moscow Boarding Houses or Nursing Homes
After screening complex geriatric assessment (CGA) the participants will undergo geriatric rehabilitation programs. After termination of 21-day program, CGA will be repeated and subjects will get a program of long-term…
- Trial name
- POSTSCRIPTUM (NCT05740436)
- Testing
- Geriatric rehabilitation program based on CGA
- Where
- Russia
- Volunteers
- 420 people
- Sponsor
- Pirogov Russian National Research Medical University
Old Age; Debility, Satisfaction
TIKeasy TAblet satisfaCtion (TikTac)
In the last ten years, gerontechnology is becoming an increasing topic in geriatric medicine. Nevertheless, there are still few studies assessing the usability of technologies in old patients, especially when they are…
- Trial name
- TikTac (NCT04091152)
- Testing
- usability assessment
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Frailty
SOLAR- Frailty Screening and Multidisciplinary Assessment of Older Adults in the Emergency Department
SOLAR is a randomised control trial exploring the role of Comprehensive Geriatric Assessment (CGA) in older adults who screen positive for frailty based on the Identification of Seniors at Risk (ISAR) tool the the Emergency…
- Trial name
- SOLAR (NCT04629690)
- Testing
- SOLAR
- Where
- Ireland
- Volunteers
- 229 people
- Sponsor
- University of Limerick
Frailty
An End-to-end System for Assessment and Intervention of Frailty
The study aims to evaluate the feasibility and effectiveness of using SAIF (an end-to-end System for Assessment and Intervention of Frailty) to reduce the risk and delay the progress of physical frailty.
- Trial name
- SAIF (NCT05371210)
- Testing
- SAIF
- Where
- Singapore
- Volunteers
- 105 people
- Sponsor
- Tan Tock Seng Hospital
Frailty, Ventral Hernia
Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair
The purpose of this study is to assess the physical fitness of patients undergoing hernia repair and correlate the postoperative outcomes and recovery as well as assess the impact of a targeted physical exercise program…
- Trial name
- NCT06874413
- Testing
- Prehabilitation, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Prisma Health-Upstate
Emergencies, Aging
Comprehensive Geriatric Assessment in an Emergency Department
Purpose Frailty and multi-morbidity have been associated with increased pressure on Emergency Departments (ED), higher hospital admissions and more risks for patients arising from the ED stay.
- Conditions
- Emergencies, Aging, Geriatric Assessment, Patient Discharge
- Trial name
- CGA_ED (NCT03786250)
- Testing
- Geriatric Assessment
- Where
- Spain
- Volunteers
- 450 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Frail Elderly Syndrome, Frailty
Seated Physical Activity in Ageing
This trial will take the form of a feasibility study; designed to assess the feasibility of a proposed future clinical trial in this setting.
- Conditions
- Frail Elderly Syndrome, Frailty, Physical Activity
- Trial name
- SPAA (NCT03141866)
- Testing
- Exercise Intervention 1: Move It Or Lose It (MIOLI), Exercise Intervention 2: Machine-based resistance training intervention
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Birmingham
Malnutrition Elderly, Primary Care
Brief Training Program for General Practitioners on Malnutrition and Adapted Physical Activity
This randomized, parallel-group interventional study evaluated the impact of brief targeted training on general practitioners' knowledge and professional practices regarding malnutrition and adapted physical activity (APA).
- Conditions
- Malnutrition Elderly, Primary Care, General Practitioner Education, Older Adults (65 Years and Older)
- Trial name
- NCT07794657
- Testing
- Malnutrition training, Adapted physical activity training
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Nantes University Hospital
Breast Cancer, Colorectal Cancer
Geriatric Assessment and Promotores (GAP) Pilot Feasibility Study
The goal of this clinical trial is to test a new way to help older adults who have had cancer. The researchers want to see if a program that assesses participants health and aging is achievable and makes a difference.
- Conditions
- Breast Cancer, Colorectal Cancer, Prostate Cancer
- Trial name
- GAP (NCT06125145)
- Testing
- Geriatric Assessment and Promotora Coaching
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Sarcopenia, Frailty
Effectiveness of Individual Physical Activity Programs to Prevent Sarcopenia and Frailty Among Older Adults
Sarcopenia and frailty could be prevented and rehabilitated through individual physical activities in the form of combined exercise that could be practiced at home in daily life.
- Trial name
- NCT06149871
- Testing
- Physical activity
- Where
- Thailand
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Thailand
Type 2 Diabetes Mellitus, Hypoglycemia
Hypoglycemia Risk Assessment in Elderly and Senile Female Patients With Type 2 Diabetes Mellitus
Hypoglycemia poses a particular danger for elderly patients with type 2 diabetes mellitus (T2DM). According to data, more than 30% of patients aged 60-69 years experience hypoglycemic episodes, and among persons over 85 years…
- Conditions
- Type 2 Diabetes Mellitus, Hypoglycemia, Frailty, Sarcopenia
- Trial name
- HYPOGLYCEMIA16 (NCT07887334)
- Testing
- Comprehensive Geriatric Assessment, Sarcopenia assessment, Laboratory assessment
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Samara State Medical University
Frailty Syndrome, Geriatric Health
Longitudinal Assessment of Maximal Inspiratory Pressure and Functional Capacity Following Inspiratory Muscle Training in Frail Older Adults (IMT-2)
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on maximal inspiratory pressure and functional capacity in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Geriatric Health, Respiratory Muscle Weakness, Age-Related Frailty
- Trial name
- NCT07328334
- Testing
- Inspiratory Muscle Training
- Volunteers
- 30 people
- Sponsor
- Universidad Francisco de Vitoria