Clinical trials: Physical Frailty
Plasma Cell Myeloma
Telehealth Exercise Intervention to Improve Physical Function and Frailty in Multiple Myeloma Survivors
This clinical trial examines a telehealth exercise intervention in improving physical function and frailty in multiple myeloma survivors.
- Trial name
- NCT05142371
- Testing
- Best Practice, Exercise Intervention, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- City of Hope Medical Center
FRAILTY
FRED Exergame Including Biofeeback Supervision
A pilot six-week randomised controlled trial was carried out introducing biofeedback with physiological constants as follows: systolic blood pressure, diastolic blood pressure, heart rate and blood oxygen saturation in the…
- Trial name
- NCT03425227
- Testing
- FRED EXERGAME
- Where
- Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Begoña Garcia Zapirain
Frail Elderly Syndrome, Anesthesia Complication
Frailty, Anesthesia and Complications.
Objectives: To assess the prevalence of frailty in patients older than 70 y/o in nephrourologic surgery. To study if preoperative frailty is an independent predictor of immediate postoperative complications, after 30 days, 6…
- Conditions
- Frail Elderly Syndrome, Anesthesia Complication, Complication of Surgical Procedure, Postoperative Delirium
- Trial name
- FRAC (NCT04264351)
- Where
- Spain
- Volunteers
- 413 people
- Sponsor
- Fundacio Puigvert
GI Cancer
Effect of Geriatric Intervention in Frail Patients with Gastric, Biliary, and Pancreatic Cancer Receiving Palliative Chemotherapy
Gastric, biliary and pancreatic cancer are commonly malignancies from gastro- intestinal tract in Taiwan. Because lack of specific symptoms at presentation and effective screening methodology, majority of these patients are…
- Trial name
- NCT06040801
- Testing
- Frailty intervention measures
- Where
- Taiwan
- Volunteers
- 138 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Disease, Frailty
Association of Centre of Excellence Self-Administered Questionnaire (CESAM) Score and Frailty Levels
This study evaluates the association of the Self-Administered questionnaire (CESAM) score and its stratification of frailty in four levels with incident adverse health events in older community dwellers and to compare this…
- Conditions
- Chronic Disease, Frailty, Disability Physical
- Trial name
- NCT03962972
- Testing
- Frailty evaluation
- Where
- Canada
- Volunteers
- 1,741 people
- Sponsor
- Jewish General Hospital
Fraility, Anxiety, Preoperative
The Relationship Between Preoperative Anxiety Level and Frailty Score in Elderly Patients Scheduled for Elective Hip Arthroplasty: A Prospective Observational Study
Frailty is a state of vulnerability resulting from decreased physiological reserve across multiple organ systems, impairing an individual's ability to withstand stressors.
- Conditions
- Fraility, Anxiety, Preoperative, Hip Arthroplasty
- Trial name
- NCT07633483
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Aging, Cognitive Decline
Blood Flow Restriction and High-intense Resistance Training in Aging: Interactions Between Neuroplasticity and Muscle
BRAIN-M is a randomized controlled trial designed to examine the effects of a single bout or 12 weeks of blood-flow restriction training or high-intensity resistance training on cognitive function, brain health, muscular…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Frailty
- Trial name
- BRAIN-M (NCT05744167)
- Testing
- BFRT, MDRT
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Aging, Mortality
Longevity Metrics AI/ML Development Study
This study builds AI models that score diagnostic screening tests, and that predict screening results, clinical judgment, and life expectancy.
- Conditions
- Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome
- Trial name
- NCT07808619
- Testing
- AIML scored health screening battery
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Frailty
Effects of Low-Speed and High-Speed Resistance Training Programs on Frailty Status
The present study refers to a three-arm randomized controlled trial that investigated the effects of two types of RT on frailty status, physical performance, cognitive function, and blood pressure of prefrail and frail older…
- Trial name
- RTF (NCT04868071)
- Testing
- Physical Exercise
- Where
- 2 sites in Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Osteoporosis, Sarcopenia
Comprehensive Risk Assessment and Prevention Plan of Osteoporosis and Sarcopenia for the Elderly Participating in Community-based Long-term Care Services
The purpose of this project is: 1. Provide the epidemiological data of the prevalence, incidence, and risk factors of osteoporosis and sarcopenia among the elderly in rural areas. 2.
- Conditions
- Osteoporosis, Sarcopenia, Frailty
- Trial name
- NCT05104034
- Testing
- Osteoporosis screening and treatment as needed, Sarcopenia, Exercise
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Frailty Syndrome, Quality of Life
Feasibility and Effectiveness of an Additional Resistance and Balance Training in Cardiac Rehabilitation of Older Patients After Valve Surgery or Intervention
The aim of the study is to evaluate the short- and medium-term effectiveness of additional moderate dynamic resistance and balance training to the CR-program of old adults after valve surgery or intervention compared to usual…
- Conditions
- Frailty Syndrome, Quality of Life, Valve Heart Disease
- Trial name
- NCT04234087
- Testing
- Additional balance and resistance training
- Where
- Lithuania
- Volunteers
- 116 people
- Sponsor
- Lithuanian University of Health Sciences
Frail Elderly
High Intensity Interval Training Versus Moderate Intensity Continuous Training in Frail Elderly
The assessment and systematic integration of physical activity into the care pathway of frail elderly people is essential to prevent loss of independence and improve the quality of life of this population.
- Trial name
- EPAF (NCT07211334)
- Testing
- Exercise Training
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Grenoble
Critical Illness, Geriatric Assessment
Geriatric Assessment at Discharge From the Intensive Care Unit in Patients Aged 75 Years and Older: a Feasibility Study
The number of patients aged over 75 continues to grow, and, according to INSEE, will represent almost 10% of the French population in 2021, an increase of 2.4 points since 2000.
- Conditions
- Critical Illness, Geriatric Assessment, Older People, Frailty
- Trial name
- PreGEDI (NCT06513130)
- Testing
- Geriatric assessment in the 7 days following ICU discharge., No geriatric assessment in the 7 days following ICU discharge.
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Strasbourg, France
Solid Neoplasms, Solid Tumors
Integrating Geriatric 8 (G8) Screening and Cancer and Age Research Group (CARG) Toxicity Assessment Score Into Routine Care for Older Adults With Cancer
This study evaluates whether using specialized geriatric screening and toxicity prediction tools can help oncologists personalize chemotherapy dosing and reduce severe side effects in older adults with solid cancers.
- Conditions
- Solid Neoplasms, Solid Tumors, Chemotherapy-Induced Toxicity
- Trial name
- NCT07837505
- Volunteers
- 100 people
- Sponsor
- Assiut University
Sickle Cell Disease, Sickle Cell Trait
Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait
This is a cross-sectional, clinical research study comparing postmenopausal women of African Descent (AD) with different hemoglobin genotypes: normal and sickle cell trait (SCT). This research study has two purposes.
- Trial name
- NCT07083531
- Testing
- Healthy volunteers without SCT, Healthy volunteers with SCT
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- UConn Health
Frailty
SPOT-FRAILTY Assessment of Frailty in Patients Over the Age of 70 Undergoing a Cardiac Intervention
Rocha (2017), published a systematic review and meta-analysis highlighting the clinical utility of frailty scales for the prediction of post-operative complications.
- Trial name
- SPOT FRAILTY (NCT04061317)
- Testing
- Frailty Assessment
- Where
- United Kingdom
- Volunteers
- 82 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Solid Tumor, Metastatic Solid Tumor
Validation of the G8 Screening Tool for Prognostic Assessment of Frailty and Early Mortality in Elderly Individuals With Cancer: Prospective Cohort Study in Brazil
This is a prospective observational cohort study including 250 individuals aged 70 years or older newly diagnosed with solid tumors.
- Conditions
- Solid Tumor, Metastatic Solid Tumor, Recurrent Solid Tumor
- Trial name
- CORALINE (NCT07773285)
- Where
- Brazil
- Volunteers
- 250 people
- Sponsor
- Latin American Cooperative Oncology Group
Frailty at Older Adults, Health Promotion
Effects of HAPPY GO GO Game on Health of Rural Elderly
The goal of this quasi-experimental clinical trial is to evaluate the effects of the "HAPPY GO GO" somatosensory game on physical and mental health in community-dwelling older adults aged 65 years and above living in rural Chiayi…
- Trial name
- NCT07191613
- Testing
- HAPPY GO GO Somatosensory Game
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Breast Cancer, Frailty
VR for Surgical Prehabilitation and Rehabilitation
This randomized controlled trial aims to determine feasibility and acceptability of of VR-physical therapy modules for surgical patients undergoing breast or axilla surgery in order to prepare for and recover from surgery.
- Conditions
- Breast Cancer, Frailty, Surgery
- Trial name
- VR-PREP (NCT06334380)
- Testing
- Virtual Reality Modules Only, Virtual Reality Modules + Live Physical Therapist Support
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Frailty, Surgery
Cardiac Rehabilitation and Frailty Physical Training Program in Elderly Patients After Open Heart Surgery
The aim of the research - to evaluate the impact of interactive physical therapy tools for functional capacity, fear of falls, motivation and quality of life after open heart surgery due to ischemic heart disease and frailty in…
- Trial name
- NCT06385041
- Testing
- Multicomponent training group, Computer-based interactive training group
- Where
- Lithuania
- Volunteers
- 153 people
- Sponsor
- Vitalija Stonkuvienė