Clinical trials: Physiological Responses
Type 2 Diabetes Mellitus (T2DM)
Long-Term Benefits of Eccentric Cycling Exercise in Patients With Type 2 Diabetes Mellitus
The goal of this interventional study is to evaluate the long-term benefits of eccentric (ECC) cycling exercise on physiological responses, exercise capacity, and quality of life (QoL) in patients with type 2 diabetes mellitus…
- Trial name
- NCT07109102
- Testing
- Moderate-intensity eccentric cycling, High-intensity eccentric cycling, Moderate-intensity concentric cycling
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Sains Malaysia
Neonatal Intensive Care, Music Therapy
The Effect of Lullaby Listened to Preterm Babies in Neonatal Intensive Care Units on Physiological Parameters and Pain
Preterms who enter a different environment after the intrauterine period experience an adaptation process and may need special care due to conditions such as developmental disabilities or neurological disorders.
- Conditions
- Neonatal Intensive Care, Music Therapy, Pain Responses
- Trial name
- NCT05253625
- Testing
- Listening to a recorded lullaby.
- Volunteers
- 93 people
- Sponsor
- Izmir Tinaztepe University
Cardiovascular Fitness
Physiological and Perceptual Responses During 4-Second Exercise
The purpose of this study is to investigate the acute effects of different intensities (i.e., 50, 75, and 100% of maximal anaerobic power) of 4-s sprint interval exercise on physiological responses.
- Trial name
- NCT06912932
- Testing
- Preventive
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Respiratory Insufficiency
Physiological Response to Heliox21 and Air O2
This is a non-commercial study to explore the use of Heliox21 in a new patient cohort. The fundamental aim is to assess the therapeutic benefits of Heliox21 and practicalities of gas delivery in patients who require non-invasive…
- Trial name
- NCT01498432
- Testing
- Heliox21, Air O2
- Where
- United Kingdom
- Volunteers
- 38 people
- Sponsor
- University College, London
Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome
The Study Seeks to Determine Potential Correlations Between Ventilation and Hematological Alterations, Contributing to a Better Understanding of Its Physiological Effects and Optimizing Patient Management in Critical Care Settings.
The study seeks to determine potential correlations between ventilation and hematological alterations, contributing to a better understanding of its physiological effects and optimizing patient management in critical care…
- Trial name
- NCT07030114
- Testing
- complete blood tests, mechanical ventilation (MV)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Congenital Heart Disease, Disorder of Fetus or Newborn
Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
Although cardiopulmonary bypass (heart-lung machine) is a necessary component of heart surgery, it is not without consequences. Cardiopulmonary bypass initiates a potent inflammatory response secondary to the body's recognition…
- Trial name
- NCT01579513
- Testing
- Methylprednisolone
- Where
- 2 sites in United States
- Volunteers
- 190 people
- Sponsor
- Medical University of South Carolina
Physiologic Changes, Exercise
Chrysin Exercise Performance Pilot Study
This single-arm pilot study evaluates within-subject changes in aerobic capacity, heart rate responses, cycling power output, and related physiological measures in healthy adults during and after 30 days of supplementation with a…
- Conditions
- Physiologic Changes, Exercise, Physiological Changes (Heart Rate)
- Trial name
- NCT07872111
- Testing
- Chrysin LipoMicel
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Isura
Obesity, Food Craving
The Role of Emotional Arousal in Food Preference and Taste
The purpose of this study is to examine the role of stress in food craving and food consumption in obesity. Using experimentally validated guided imagery procedure, the investigators propose to examine the stress response using…
- Conditions
- Obesity, Food Craving, Food Consumption
- Trial name
- NCT02402088
- Testing
- Stress Imagery, Food Cue Imagery, Neutral-Relaxing
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Yale University
Cystic Fibrosis
Interactive Video Game Responses in Cystic Fibrosis
Cystic fibrosis (CF) is a disease that affects multiple systems, however, the accumulation of secretion in the airways contributes to the fact that pulmonary complications are the main responsible for the high rates of morbidity…
- Trial name
- Igamecf (NCT03229213)
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Healthy
Pulse Revolution: Enhancing Metabolic Health Through the Power of Processed Chickpeas
The purpose of this research is to test how processing can affect how one's body uses the nutrients in that food. For this study the researchers are examining how making different food products out of chickpeas, such as hummus or…
- Trial name
- NCT06758869
- Testing
- Control, Whole Chickpeas, Puréed Chickpeas
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Children, Postoperative Pain
Maternal Voice Versus White Noise in Pediatric Surgery
This randomized controlled study will evaluate the effects of maternal voice and white noise on postoperative pain, comfort, and physiological parameters in children aged 1 month to 3 years during the early postoperative period.
- Conditions
- Children, Postoperative Pain, Physiological Parameters, Comfort
- Trial name
- NCT07785297
- Testing
- Maternal Voice Recording, White Noise Recording
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kocaeli University
Physiological Responses to High-Intensity Exercise
Effects of the Q-Collar During High-Intensity Cycling Exercise
This study examined the effects of wearing the Q-Collar during high-intensity cycling exercise. Eleven recreationally trained male participants completed two 5-kilometer cycling time trials: one while wearing the Q-Collar and one…
- Trial name
- NCT07808710
- Testing
- Q-Collar™
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Exercise Performance
U-LABA/ICS Effects on Exercise Performance, Vilanterol
The purpose of the project is to investigate exercise performance in humans following bronchodilation induced by acute inhalation of beta2-agonist vilanterol + fluticasone furoate
- Trial name
- NCT06066606
- Testing
- Vilanterol and Fluticasone Furoate (low dose), Vilanterol and Fluticasone Furoate (high dose)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Age Related Cataracts
Evaluation of Physiological Responses at the Anterior Surface of Two (Hydrophobic Acrylic) Intraocular Lens Models
On the day of surgery, the the eye with astigmatism of at least 0.75dpt receives a Vivinex XY1A , HOYA Surgical Optics GmbH and the second eye to be operated receives an XY1, HOYA Surgical Optics GmbH.
- Trial name
- NCT04230629
- Testing
- Vivinex XY1, Vivinex XY1A
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Stress
Stress and Clinical Reasoning in Medical Students
Solving a problem in ambulatory setting may contain peripheral stress due to socio-evaluative stressors (patient's expectations about explanations) and task contingent stress due to time pressure, the necessity to take into…
- Trial name
- NCT01061255
- Testing
- Evaluation of the stress
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Aging
Physiological Responses to a Prolonged Cycling Expedition in Older Men
The aim of this study was to test the physiological response to a 2800 km cycling expedition, from Copenhagen, Denmark to Nordkapp, Norway, in a group of older male recreational cyclists.
- Trial name
- NCT02353624
- Testing
- Cycling
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diabete Type 2, Pharmacogenomic Drug Interaction
PATHS-T2D: A Recall-by-Genotype Study of Physiologic and Pharmacologic Responses
This research study aims to learn about how the body responds to food through different genetic pathways and how these responses may change during a short course of orforglipron.
- Trial name
- PATHS-T2D (NCT07739537)
- Testing
- Orforglipron
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Infant Development
Measurements of Anemia and Physiologic Tissue Response to Blood Transfusions in VLBW Infants Using Quantitative NIRS
The study quantified functional measures of red blood cell mass and oxygen in neonatal tissues using a non-invasive optical technique: near infrared optical spectroscopy .
- Trial name
- NCT00544375
- Testing
- Optical measurement
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Irvine
Healthy, Athlete
Effects of Sodium Bicarbonate on Endurance Performance
This study is investigating whether taking sodium bicarbonate, a common supplement used by endurance athletes, can improve cycling performance during prolonged exercise and in a time trial.
- Conditions
- Healthy, Athlete, Well-trained Athletes, Performance
- Trial name
- SBEP (NCT07171047)
- Where
- Austria
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Salzburg
Bipolar Depression Depressed Phase, Obesity & Overweight
The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression
This research study examines how a medication called lumateperone may affect mood symptoms, and inflammation in adults with bipolar disorder over approximately 6 weeks.
- Trial name
- NCT07699445
- Testing
- Lumateperone 42 mg
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital