Clinical trials: Positive Affect, open to volunteers
Burnout, Professional, Negative Affect
Floatation Experience in Nurses and Physicians
The goal of this observational study is to monitor the floatation experience and continue the program as long as deemed important.
- Conditions
- Burnout, Professional, Negative Affect, Positive Affect, Wellbeing
- Trial name
- NCT05977894
- Testing
- Reduced Environmental Stimulation Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Depression
Mindfulness Training During Accelerated TMS for Depression
This NIH-funded single-arm pilot tests the feasibility, acceptability, and preliminary effects of embedding brief guided mindfulness practice (via the Waking Up smartphone app) into the inter-session intervals of clinically…
- Trial name
- NCT07369557
- Testing
- Guided Mindfulness Practice using a study created web app that links to the commercially available Waking Up app
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Technology Use, Positive Affect
Best Possible Self-Tech for Middle Schoolers
The goal of this pilot clinical trial is to learn if a single-session writing exercise (i.e., Best Possible Self-Tech) can improve positive affect and prosocial technology use in a community sample of eighth graders.
- Trial name
- NCT07540819
- Testing
- Best Possible Self-Tech
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Depression, Anxiety
Brightline: Advancing Mental Health on Campus
This observational study will employ a multi-modal observation methodology, integrating data from wearable devices and smartphones to establish comprehensive digital biomarkers for identifying symptoms of mental health conditions…
- Conditions
- Depression, Anxiety, Stress, Positive Affect
- Trial name
- NCT06770075
- Testing
- Observational
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Positive Affect, Depression
Training Reward Responsiveness Through Virtual Reality
The purpose of this study is to compare the effects of Virtual Reality-Reward Training (VR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect and other clinical symptoms.
- Trial name
- NCT07219875
- Testing
- Virtual Reality-Reward Training (VR-RT), Virtual Reality-Memory Training (VR-MT)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Left Rostromedial Prefrontal Cortex - Accelerated Intermittent Theta Burst, Left Dorsolateral Prefrontal Cortex - Accelerated Intermittent Theta Burst
Causal Role of Rostromedial Prefrontal Cortex for Positive Savoring in Depression
This is a non-invasive brain stimulation and neuroimaging study that will examine how activity in the medial prefrontal cortex influences reward processing, particularly positive savoring, in individuals with depression.
- Conditions
- Left Rostromedial Prefrontal Cortex - Accelerated Intermittent Theta Burst, Left Dorsolateral Prefrontal Cortex - Accelerated Intermittent Theta Burst, Left Primary Somatosensory Cortex - Accelerated Intermittent Theta Burst
- Trial name
- rmPFC-Savoring (NCT07467473)
- Testing
- Accelerated Intermittent Theta Burst Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Florida State University
Perceived Stress, Positive and Negative Affect
Efficacy of Interactive Audio-based Mindfulness ChatGPT-Powered Intervention on Well-being
Brief mindfulness intervention is a short form is a form of short-duration practice, typically delivered for around 30 minutes or less (Howarth et al., 2019).
- Conditions
- Perceived Stress, Positive and Negative Affect, State Anxiety, Self Control
- Trial name
- NCT07333365
- Testing
- Interactive Mindfulness Breathing ChatGPT-Powered Intervention, Interactive Mind Wandering ChatGPT-Powered Intervention, Mindfulness Breathing Audio-only
- Where
- Singapore
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Singapore Management University
Type 1 Diabetes Mellitus (T1DM), Anxiety
Drawing and Writing Activities in Adolescents With Type 1 Diabetes
This randomized controlled trial aims to evaluate the effects of drawing and writing activities on anxiety and positive and negative affect in adolescents with type 1 diabetes.
- Trial name
- NCT07830082
- Testing
- Drawing and Writing Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Gazi University
Preoperative Anxiety, Laparoscopic Cholecystectomy
Humor-Based Video Intervention on Preoperative Anxiety Veya Humor Video and Recovery in Cholecystectomy
This study aims to evaluate whether watching a short humor-based video before surgery can reduce anxiety and negative emotions and increase positive emotions in patients undergoing elective laparoscopic cholecystectomy…
- Trial name
- NCT07861438
- Testing
- Humor-Based Video Intervention, Routine Preoperative Care and Education
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Loneliness
Reducing Loneliness Among Older Adults Through Enhancing Positive Affect
This study aims to evaluate the effectiveness of two psychosocial interventions-Tele-Positive Affect (Tele-PA) and Tele-Behavioral Activation (Tele-BA)-compared to active control (telephone-delivered friendly visit, Tele-FV) in…
- Trial name
- NCT07021872
- Testing
- Tele-Positive Affect Intervention, Tele-Behavioral Activation Intervention, Tele-Friendly Visit
- Where
- Hong Kong
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Emotional Distress, Anhedonia
Promoting Positive Emotions in Adolescents Using Positive Events Training: An Indicated Approach
Research shows that high positive emotionality is an essential ingredient in building resilience in youngsters, especially those with a vulnerability to develop depressive symptomatology.
- Trial name
- iPET (NCT07288541)
- Testing
- Positive Events Training (PET)
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- KU Leuven
Depression, Parent-Child Relations
Parent Encouragement And Coaching of Happiness in Youth
The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response to reward. The main questions it aims to answer are: Aim 1.
- Trial name
- PEACHY (NCT06725160)
- Testing
- Parent Coaching, Active Control
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
High Arousing Positive Emotion, Low Arousing Positive Condition
Do Different Arousal Levels Affect Pressure Pain Thresholds?
This study examines whether emotional arousal level alone, while maintaining positive emotional valence, can influence pressure pain thresholds (PPTs) in healthy adults.
- Trial name
- DDEALAPPT (NCT07802444)
- Testing
- Emotional high arousing intervention, Low arousal intervention
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
HIV/AIDS, HPV Infection
ORCHID: An Online Intervention for Persons With HIV (Miami)
The purpose of this research is to test ORCHID (Optimizing Resilience \& Coping with HIV through Internet Delivery), a skills-building intervention that improves mental health status for persons with HIV, who are at-risk for…
- Trial name
- ORCHID-Miami (NCT05935644)
- Testing
- ORCHID
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Depression
Positive Affect Treatment for Adolescents With Early Life Adversity
Youth exposed to early life adversity (ELA) are known to be at greater risk for depression and suicidality and account for almost half of the youth suffering from psychiatric diseases today.
- Trial name
- PAT4ELA (NCT06273137)
- Testing
- Positive affect treatment, Supportive psychotherapy (SUP)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Healthy
A Study in Healthy People to Measure How Different Doses of Verducatib Affect the Heart
The main objective of this trial is to evaluate the effects of verducatib in the range of therapeutic to supra-therapeutic exposures on the QT/QTc-interval and other ECG parameters
- Trial name
- NCT07760246
- Testing
- Verducatib, Moxifloxacin
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Depression Symptoms
Email-Delivered Digital Positive Affect Intervention for Young Adults in Zimbabwe
This study evaluates the feasibility, acceptability, and preliminary efficacy of a brief email-delivered positive affect intervention for young adults in Zimbabwe.
- Trial name
- SPARK-Z (NCT07682779)
- Testing
- Email-Delivered Positive Affect Intervention, Psychoeducational Control
- Where
- Zimbabwe
- Volunteers
- 100 people
- Sponsor
- Vilnius University
Emotional Distress, Anhedonia
Positive Events Training to Enhance Positive Emotions in Adolescents With Elevated Depressive Symptoms: An N=1 Trial
Research shows that high positive emotionality is an essential ingredient in building resilience in youngsters, especially those with a vulnerability to develop depressive symptomatology.
- Trial name
- iPET N=1 (NCT07825285)
- Testing
- Positive Events Training (PET)
- Where
- Belgium
- Volunteers
- 1 people
- Sponsor
- KU Leuven
Mild to Moderate Anxiety and Depression
Digital Positive Affect Intervention Study
Anxiety and depression are highly prevalent mental health disorders that impose a significant burden on individuals and public health systems worldwide (GBD 2019 Mental Disorders Collaborators, 2022).
- Trial name
- NCT06978257
- Testing
- Digital positive affect intervention (PAI), Self-monitoring intervention
- Where
- Singapore
- Volunteers
- 2,400 people
- Sponsor
- National University of Singapore
Healthy Aging, Elderly (People Aged 65 or More)
Sandplay-Act. Older: Structured Sandplay Activity for Older Individuals
This research was planned to determine the effect of structured sandplay activities on positive and negative affect and levels of meaning in life in elderly individuals.
- Trial name
- NCT07735351
- Testing
- Sandplay-Act. Older: Structured Sandplay Activity for Older Individuals, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University