Clinical trials: Prescription
Inflammatory Bowel Diseases
A Development of Inflammatory Bowel Disease Pattern Identification Algorithm Using Case Series Data
This study aimed to identify inflammatory bowel disease (IBD) patterns based on presenting symptoms and to suggest algorithms for determining pattern and herbal prescriptions for corresponding patterns.
- Trial name
- NCT04296500
- Testing
- Decision tree modeling
- Where
- South Korea
- Volunteers
- 67 people
- Sponsor
- Hyangsook Lee, KMD, PhD
Ankle Osteoarthritis, Flat Foot or Pes Planus
Orthotic Dose Response Study
This study will investigate the effect of foot orthoses on two common conditions (ankle osteoarthritis and symptomatic adult onset flat feet) by using a custom biplane X-ray system the group has developed to very accurately and…
- Trial name
- ODRS (NCT02629731)
- Testing
- custom orthoses with varying degrees of hindfoot posting
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Baseline Epidemiologic Assessment
Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB)
The main objectives of this study are to provide surveillance/descriptive data to (a) assess utilization of MorphaBond ER and selected comparators overall and by age group and census regions using nationally-projected quarterly…
- Trial name
- BEAD-MB (NCT04033094)
- Testing
- MorphaBond ER, Comparator Drug
- Where
- United States
- Volunteers
- 17,566 people
- Sponsor
- Daiichi Sankyo
Heart Failure
Efficacy and Safety of ICD Remote Monitored Exercise Testing to Improve Heart Failure Outcomes: REMOTE HF-ACTION
This single center randomized controlled trial will involve 50 medically stable outpatients with HF, reduced ejection fraction, and previously implanted ICD or CRT-D devices followed longitudinally on the Abbott Medical Merlin…
- Trial name
- x (NCT04629066)
- Testing
- Remote Cardiac Rehabilitation (CR)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Duke University
Opioid Overdose
UnityPhilly Response App for Overdose Reversal
The goal of this clinical trial is to discover if an overdose prevention app (UnityPhilly) can encourage citizen responders to respond and prevent opioid overdoses using the UnityPhilly app.
- Trial name
- NCT06466005
- Testing
- UnityPhilly app
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Drexel University
Obesity
Evaluating the Efficacy of AI-Guided (GenAIS TM) vs. Standard Physician-Guided Dietary Supplement Prescriptions for Weight Loss in Obese Patients
Obesity, a chronic disease characterized by excessive fat accumulation, significantly impacts health. Genetic factors influence the development of obesity by affecting behavioral, dietary habits, and metabolic processes.
- Trial name
- NCT06458296
- Testing
- Control Group, AI-Guided Group
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- S.LAB (SOLOWAYS)
Loneliness
Testing a Nature-based Social Intervention on Loneliness: the RECETAS-BCN Trial
RECETAS (Re-imagining Environments for Connection and Engagement: Testing Actions for Social Prescribing in Natural Spaces) is an European project (H2020 No 945095) that aims to reduce loneliness by linking lonely people to…
- Trial name
- RECETAS-BCN (NCT05488496)
- Testing
- Nature-based social intervention (NBSI), referred as Friends in Nature (FiN), Usual care + menu with nature-based activities
- Where
- Spain
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Depression in Adolescence, Anxiety
Application for Arts-Based Social Prescribing
The goal of this clinical trial is to learn if a personalized arts-based social prescribing program, Art Pharmacy, delivered through a mobile app (SocialRx App) can improve mental health and social connectedness in adolescents…
- Conditions
- Depression in Adolescence, Anxiety, Loneliness, Social Connectedness
- Trial name
- NCT07593443
- Testing
- Art Pharmacy, Stable treatment
- Volunteers
- 230 people
- Sponsor
- SocialRx Inc
Cardiovascular-kidney-metabolic Syndrome, Diabete Type 2
SWitching to Appropriate Prescription in Cardiovascular-Kidney-Metabolic Syndrome
SWAP-CKM (SWitching to Appropriate Prescription in Cardiovascular-Kidney-Metabolic Syndrome) is a pragmatic, cluster-randomized clinical trial designed to evaluate whether electronic health record (EHR)-based alerts can improve…
- Conditions
- Cardiovascular-kidney-metabolic Syndrome, Diabete Type 2, Chronic Kidney Disease, Heart Failure
- Trial name
- SWAP-CKM (NCT07910968)
- Testing
- Real-Time EHR Prompts and Audit-and-Feedback Reports
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Kaiser Permanente
Opioid Use
Development of a Risk Prediction Screening Tool for Opioid-Prescription Injury (STOP Injury) in Older Adults Initiated on Opioids From the Emergency Department
The long-term goal of this project is to promote responsible opioid prescribing, immediately improving patient safety and ultimately decreasing healthcare costs by reducing older adult morbidity and mortality due to…
- Trial name
- STOP Injury (NCT03836235)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Florida
Narcotic Use
Narcotics Inpatient / Outpatient
Managing pain in postoperative patients presents challenges in striking a balance between achieving adequate pain control and over-prescribing opioids that have the potential to contribute to the opioid epidemic.
- Trial name
- NCT03728517
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Indiana University
Osteo Arthritis Knee, Osteoarthritis
The Technology, Exercise Programming, and Activity Prescription for Enhanced Mobility (TEAM) Study
Many individuals with osteoarthritis (OA) (up to 45%) are referred to an orthopaedic surgeon for a joint replacement prematurely or will not be candidates for surgery.
- Conditions
- Osteo Arthritis Knee, Osteoarthritis, Hip Arthritis
- Trial name
- TEAM (NCT04544904)
- Testing
- PAARx, JM
- Where
- Canada
- Volunteers
- 356 people
- Sponsor
- Western University, Canada
Knee Osteoarthritis
Heart Rate Variability Guided Physical Activity and Exercise Prescription in Individuals With Knee Osteoarthritis
The aim of this trial is to conduct a 12-week randomised controlled trial comparing an HRV-guided home exercise program with traditional home exercise program for individuals with knee osteoarthritis (KOA), followed by 24-week…
- Trial name
- HOPE-OA (NCT07391449)
- Testing
- HRV-guided home exercise prescription, Traditional Home Exercise
- Where
- Hong Kong
- Volunteers
- 240 people
- Sponsor
- The Hong Kong Polytechnic University
Antidepressive Agents, Aged
Association Between Prescription of Antidepressants and Delirium in the Elderly : Analysis From the World Health Organization Global Database
Delirium is a frequent reason for hospitalisation of the elderly. Associations between the prescription of some medicines and the risk of delirium have already been demonstrated.
- Conditions
- Antidepressive Agents, Aged, Delirium
- Trial name
- NCT05356078
- Testing
- Antidepressant
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- University Hospital, Caen
Low Back Pain, Opiate Addiction
Study of Opioid Use After Lumbar and Cervical Spine Surgery
The purpose of this project is to assess the impact of an educational video on the use of prescription opioid medication during a 6-month period following spine surgery.
- Conditions
- Low Back Pain, Opiate Addiction, Neck Pain
- Trial name
- SOULCS (NCT02674711)
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Physiological Post-Concussion Disorder, Post-Concussion Syndrome
Sub-maximal Exercise Prescription in Adolescents With Physiological Post-concussion Disorder
Although the vast majority of individuals sustaining a sport-related concussion (SRC) will receive medical clearance to return to sport within 7-10 days, approximately 30% of children and adolescents reporting to the emergency…
- Conditions
- Physiological Post-Concussion Disorder, Post-Concussion Syndrome, Traumatic Brain Injury, Rehabilitation
- Trial name
- NCT03367507
- Testing
- Sub-symptom aerobic exercise
- Where
- 2 sites in Canada
- Volunteers
- 136 people
- Sponsor
- Sport Injury Prevention Research Centre
Physician's Practice Patterns
Electronic Prescription Data to Improve Primary Care Prescribing
This is a randomised controlled study to evaluate the effect of providing prescribing feedback that includes individual patient data to General Practitioners (GP) in Scotland on high risk or low quality prescribing.
- Trial name
- EPIPP (NCT02512198)
- Testing
- Prescription Data Feedback to GP Practices
- Where
- United Kingdom
- Volunteers
- 236 people
- Sponsor
- University of Dundee
Complementary Investigations
Analysis of Complementary Exams Prescriptions From an Emergency Unit of a University Hospital
The objective of this study is to evaluate the appropriateness of prescribing additional tests in the emergency unit of the University Hospital of Monastir.
- Trial name
- CEinED (NCT04455087)
- Testing
- sensitization
- Where
- Tunisia
- Volunteers
- 2,000 people
- Sponsor
- University of Monastir
Respiratory Infection, Respiratory Infections in Children
Impact of the Use of CRP on the Prescription of Antibiotics in General Practitioners
Respiratory infections, including episodes of coughing with fever, are the main cause of outpatient antibiotic prescription, while a minority of them are linked to bacterial infections requiring antibiotic.
- Trial name
- VIP (NCT03540706)
- Testing
- Care with C-reactive protein assay in micro method
- Where
- 14 sites in France
- Volunteers
- 406 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Alzheimer Disease, Dementia Alzheimers
An Electronic Clinical Decision Support Tool to Reduce Low-value Antipsychotic Prescriptions
The goal of this study will be to design, implement and test the impact of a quality improvement (QI) intervention that uses an EHR CDS tool among physicians newly ordering an antipsychotic medication for older adults with ADRD.
- Conditions
- Alzheimer Disease, Dementia Alzheimers, Dementia of Alzheimer Type
- Trial name
- NCT04851691
- Testing
- EHR CDS, Usual Care
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of California, Los Angeles
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