Clinical trials: Randomized-controlled Trial
Human Papilloma Virus
A Cohort Study of Hyperthermia and Imiquimod for the Treatment of Flat Warts
flat warts are a superficial viral skin disease, extremely common in childhood.Treatment of warts is often difficult and involves different destructive procedures.Although several pharmacological and physical topical treatments…
- Trial name
- NCT05146895
- Testing
- Imiquimod treatment, Local Hyperthermia at 44℃
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Young Adults
High-Intensity Interval Resistance Training and Low-to-Moderate-Intensity Resistance Training in Upper Extremity Muscles
High-intensity interval resistance training (HIIRT) has emerged as a time-efficient alternative to conventional resistance training; however, evidence regarding upper-extremity-focused HIIRT and its multidimensional effects…
- Trial name
- NCT07752901
- Testing
- High-Intensity Interval Resistance Training (HIIRT), Low-to-Moderate-Intensity Resistance Training (LMRT)
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy
A Study of JNJ-64281802 Against Dengue Serotype 1 Infection in a Dengue Human Challenge Model in Healthy Adult Participants
The purpose of this study is to assess the antiviral activity of JNJ-64281802 versus placebo in terms of reduction of dengue virus 1 (DENV-1) ribonucleic acid (RNA) viral load (VL).
- Trial name
- NCT04480736
- Testing
- JNJ-64281802 High dose, JNJ-64281802 Medium dose, JNJ-64281802 Low dose
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Pain Control in Heel Prick Procedure
Comparing 0.2 ml and 0.5 ml Oral 24% Sucrose Solution for Pain Relief During Heel Prick in Neonates With Historical Controls
The goal of this clinical trial is to determine whether a lower dose of oral 24% sucrose solution provides pain relief that is non-inferior to a higher dose during routine heel-prick procedures in term neonates.
- Trial name
- Sucrose (NCT07784322)
- Testing
- 24% oral sucrose
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kwong Wah Hospital
Patient With IV Cannula Induce Phlebitis
Comparison of Magnesium Sulphate Versus Cold Compress in IV Cannula Induces Phlebitis
The use of intravenous (IV) devices is an integral part of patient care in hospitals, clinics, maternity home etc. approximately 80% of hospitalized patients receive I.V therapies.
- Trial name
- NCT06072729
- Testing
- comparison of magnesium sulphate versus cold compression
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Ridge Preservation, Alveolar Bone Loss
Evaluation of Autogenous Demineralized Dentin Graft for Ridge Preservation With and Without Injectable Platelet Rich Fibrin
Ridge preservation should be considered whenever possible after tooth extraction. Whether implant placement would be performed or for aesthetic consideration at pontic sites when conventional bridge is planned.
- Conditions
- Ridge Preservation, Alveolar Bone Loss, Dentin Graft
- Trial name
- NCT05437172
- Testing
- injectable platelet rich fibrin with demineralized dentin graft, demineralized dentin graft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Implant Stability, Low Speed Drilling
Clinical Evaluation of Biological Drilling Osteotomy Protocol Versus Conventional Drilling Osteotomy Protocol
This study aims to evaluate the effect of biological drilling osteotomy protocol compared to conventional osteotomy protocol in delayed implant placement in the posterior mandible regarding implant stability Type of study design…
- Trial name
- NCT06992557
- Testing
- Biological drilling osteotomy protocol, Conventional drilling osteotomy protocol
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthognathic Relapse
Effect of Botox Injection in Anterior Belly of Digastric on Skeletal Relapse Following Mandibular Advancement Surgery
The purpose of this study is to test whether Botox injection in anterior belly of digastric muscle in BSSO for mandibular advancement surgery could reduce the tendency of postoperative relapse.
- Trial name
- NCT05573581
- Testing
- Botox
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immunity
the Efficacy and Safety of Curcuma Longa Extract Mixture on Immune Enhancement
This study was conducted to investigate the efficacy and safety of Curcuma longa extract mixture on immune enhancement
- Trial name
- NCT05324800
- Testing
- Curcuma Longa Extract Mixture
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Cesarean Section Rates
Reducing Cesarean Section Rates and Enhancing Vaginal Delivery in Greece: a Stepped-Wedge Randomized Controlled Trial
It is becoming increasingly apparent that there is an urgent need to systematically investigate the rising cesarean section (CS) rates in Greece and develop interventions to substantially reduce these rates.
- Trial name
- ENGAGE (NCT04504500)
- Testing
- HSOG guidelines application, Interactive workshops and courses, Feedback through follow-up meetings
- Where
- Greece
- Volunteers
- 6,029 people, healthy volunteers welcome
- Sponsor
- Hellenic Society of Obstetrics and Gynecology
Digital Privacy, Digital Literacy
Digital Privacy Awareness in Gifted Students
This randomized controlled trial aims to examine gifted and talented students' perceptions and concerns regarding digital privacy within the context of their digital literacy.
- Conditions
- Digital Privacy, Digital Literacy, Online Privacy Awareness
- Trial name
- NCT07433244
- Testing
- Digital Literacy and Digital Privacy Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Giresun University
Acute Respiratory Tract Infections, Respiratory Infection Prevention
Effectiveness of Education on Preventive Measures Against Acute Respiratory Tract Infections in School-Age Children
This study aimed to evaluate the effectiveness of an animation video-supported education program on preventive measures against acute respiratory tract infections among first-grade primary school children.
- Conditions
- Acute Respiratory Tract Infections, Respiratory Infection Prevention, Hand Hygiene, Respiratory Hygiene
- Trial name
- NCT07654712
- Testing
- Animation Video-Supported Education on Preventive Measures Against Acute Respiratory Tract Infections
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Delayed Onset Muscle Soreness, DOMS
COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS)
The study is designed as a proof of concept, single-center, randomized, double-blind, placebo controlled study to assess the safety and efficacy of Comboprofen (Ibuprofen + Magnesium + Vitamin C) compared to placebo, Ibuprofen…
- Trial name
- NCT03223519
- Testing
- Comboprofen, Ibuprofen, Magnesium
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Spherium Biomed
High Altitude Pulmonary Edema
Prevention of High Altitude Pulmonary Edema
A double-blind placebo controlled study To compare the effect of tadalafil and dexamethasone versus placebo on Ppa and pulmonary edema formation in subjects susceptible to HAPE.
- Trial name
- NCT00274430
- Testing
- dexamethasone 8 mg bid, tadalafil 10mg bid
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Injections
Effect of Training on IM Injection Practices
The aim of this study is to observe how many nurses perform the steps of creating an air lock, identifying the ventrogluteal site, and applying the Z-track technique in intramuscular injections after theoretical and practical…
- Trial name
- NCT05510492
- Testing
- EDUCATION, APPLIED EDUCATION
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Nazike Duruk
Hayfever
Lactobacillus Acidophilus L92 on Markers of Allergic Inflammation by Nasal Provocation With Grass Pollen
This is a placebo controlled double-blind single center study initiated and sponsored by CALPIS, Inc., Japan, and CALPIS U.S.A., Inc., Torrance, CA.
- Trial name
- NCT00554736
- Testing
- Lactobacillus acidophilus L-92
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Dental Caries
Cost-efficacy of Silver Diammine Fluoride in Erupting Molars
This study aims to evaluate the cost-effectiveness of 30% silver diammine fluoride in the treatment of clinically caries lesions in enamel, on occlusal surfaces in first permanent molars compared to a control group that performs…
- Trial name
- NCT01508611
- Testing
- 30% silver diammine fluoride, Oral hygiene
- Where
- Brazil
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Immediate Implantation of Two-piece Zirconia Dental Implants
Clinical Outcome of Two-piece Zirconia Implants in Immediate Implant Placement
The purpose of the study is to test whether a two-piece zirconia implant is as reliable in the indication of immediate implant placement as a standard titanium implant.
- Trial name
- NCT05369299
- Testing
- Implant Straumann® Pure Ceramic Two Piece Implant, two-piece titanium implant Neoss® ProActive Tapered Implant
- Where
- Austria
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Ebola Virus Disease
Safety and Immunogenicity of the rVSVΔG-ZEBOV-GP Ebola Virus Vaccine Candidate in Children Living in Lambaréné, Gabon
LA rVSVΔG-ZEBOV-GP -02-PED is a Phase 1/2, randomized, controlled open label trial. The LA rVSVΔG-ZEBOV-GP -02-PED trial aims primarily to assess the clinical significance of shedding of the rVSV RNA following vaccination with…
- Trial name
- EBOLAPED (NCT05130398)
- Testing
- rVSVΔG-ZEBOV-GP, V920, Fibre and equilibrate breakfast and lunch, Active detection and treatment of pathogens
- Where
- Gabon
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Dental Implant Placement
Buccal Soft Tissue Contour Changes After Immediate Implant Placement with or Without Connective Tissue Graft
Statement of the problem: Using customized contoured healing abutments at the time of immediate implant placement is a treatment modality to improve esthetics by maintain the soft tissue contour.
- Trial name
- NCT04309006
- Testing
- CTG and customized healing abutment, CTG and conventional healing abutment
- Where
- 2 sites in Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Misr International University
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