Clinical trials: Resistance
Obesity, Morbid, NASH - Nonalcoholic Steatohepatitis
Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity
This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin…
- Conditions
- Obesity, Morbid, NASH - Nonalcoholic Steatohepatitis, Chronic Inflammation
- Trial name
- NCT04232566
- Testing
- Bariatric surgery
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Insulin Resistance, Oxidative Stress
Microencapsulated Fish Oil or Conjugated Linoleic Acid in Metabolic Syndrome
Our aim was to assess the effects of a hypocaloric diet, including diet fruit jelly with microencapsulated fish oil or conjugated linoleic acid or placebo, on anthropometry, body composition, insulin resistance and lipid profile…
- Conditions
- Insulin Resistance, Oxidative Stress, Lipid Profile, Blood Pressure
- Trial name
- NCT02183922
- Testing
- microencapsulated conjugated linoleic acid, microencapsulated fish oil, light fruit jam
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Insulin Resistance
Basic Research Study to Examine the Relation Between Muscle Insulin Resistance and Lipid Production in the Liver.
The purpose of this study was to examine the pathophysiology of insulin resistance and the relation to the metabolic syndrome in humans.
- Trial name
- NCT02196051
- Testing
- one bout of 45 minutes exercise
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Yale University
Aging
The Effect of Velocity Training in Functionally Limited Elderly
We are exploring a unique weight-training program for men and women 65 years or older that emphasizes high speed training. We believe that the speed at which muscles move may be more important to the performance of functional…
- Trial name
- NCT01211496
- Testing
- High-speed power training, Slow-speed strength training
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Blood Glucose, Insulin Sensitivity
A Randomized, Crossover Study to Assess the Effects of Dietary Fiber-containing Bars on Glucose and Insulin Responses
This randomized, crossover study will include four clinic visits: one screening (day -7) and three test visits (days 0, 2, 4). The objective of this study is to assess the effects of dietary fiber-containing bars, at two doses of…
- Conditions
- Blood Glucose, Insulin Sensitivity, Dietary Fiber
- Trial name
- NCT03796286
- Testing
- Medium-fiber bar, High-fiber bar, Control bar (0 g fiber)
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Weakness, Muscle
Blood Flow Restriction Training for People With Disabilities
A large portion of the American population live with disabilities. People with disabilities can find it difficult to perform standard exercise routines. Regular exercise is necessary to be healthy, especially as people age.
- Trial name
- NCT06441422
- Testing
- Blood flow restriction training, No blood flow restriction training
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Falciparum Malaria, Antimalarials
The Impact of Artemether-Lumefantrine on Genes Associated With Antimalarial Resistance
The newly introduced antimalarial drug artemether-lumefantrine is currently recommended as second line antimalarial in Sudan. Recurrent infection after treatment with this drug has been associated with selection of certain genes…
- Trial name
- NCT00440752
- Where
- Sudan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tropical Medicine Research Institute
Bacterial Resistance to Antimicrobial
Prevalence of Digestive Carriage of Integrons
Bacterial resistance to antimicrobials is an increasing problem. Doctors occasionally face genuine therapeutic dead-ends, when attempting to cure nosocomial infections and, more and more frequently, community-acquired infections.
- Trial name
- APIHA (NCT01985217)
- Where
- France
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Metabolic Syndrome X
Effects of Dietary Proteins on Hepatic Lipid Metabolism
Individuals submitted to a high-fat or a high-fructose/sucrose diet develop, over a 6 day-period, several features of the metabolic syndrome, including increased plasma triglycerides, increased intrahepatic lipids, and decreased…
- Trial name
- NCT00558740
- Testing
- high protein intake
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Metabolic Syndrome
The Pick Two to Stick To Habit Development Intervention
Metabolic syndrome (MetS) is a leading risk factor for chronic disease among African American/Black populations. Fostering habit development offers a promising new approach to improving the effectiveness of lifestyle programs for…
- Trial name
- P2S2 (NCT03370419)
- Testing
- Treatment, Usual care
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Diabetes, Hypertension
FFA Hypertension and Inflammation in Lean and Obese Subjects
Although a large number of obese patients develop high blood pressure, the cause is unknown. The purpose of this study is to look at the effect of high fatty acids (a type of fat) in the development of high blood pressure in…
- Conditions
- Diabetes, Hypertension, Obesity
- Trial name
- FFAADA (NCT00721617)
- Testing
- Intralipid 20%, Normal Saline, Oral fat load
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Metabolic Syndrome
Determination Physical Activity Levels,Quality Life,Depression and Fatigue Severity Individuals With Metabolic Syndrome
The aim of the study was to determine the Physical Activity Levels, Quality of Life, Depression and Fatigue Severity of Individuals with Metabolic Syndrome.
- Trial name
- NCT05184634
- Testing
- PHYSICAL ACTIVITY LEVELS, DEPRESSION LEVELS, FATİGUE SEVERİTY
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Büşra Sarıkaya
Hypertrophy, Resistance Training
Quantification of Internal Training Load
The aim of this study is to determine whether the distribution of internal load predicts the distribution of muscle hypertrophy among hamstring heads after a 10-week resistance exercise program.
- Conditions
- Hypertrophy, Resistance Training, Muscle
- Trial name
- QUADRATURE (NCT06164249)
- Testing
- strength training
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Université de Nantes
Venous Thrombosis, Insulin Resistance
Oral Verses Patch Trial In Menopausal Women - Individualisation of Oestrogen Therapy
Ultra-low-dose oral E2/D will have more beneficial effects than trans-dermal HRT on lipids and insulin resistance in postmenopausal women, whilst adverse effects on coagulation will be avoided.
- Trial name
- OPTIMISE (NCT02264743)
- Testing
- Femoston Conti, EVOREL® CONTI
- Where
- 3 sites in United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Muscle Weakness
Effects of Simultaneous Balance and Resistance Training in Older Adults
Aging results in a gradual decline of physical abilities and consequently in functional impairments which increases the risk of falls in elderly people.
- Trial name
- NCT02555033
- Testing
- Resistance training, Instability resistance training
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Kassel
Metabolic Syndrome (MetS)
Preliminary Effect of a Health Information Literacy Enhancement Program for Individuals With Metabolic Syndrome
The purpose of this study is to evaluate the preliminary effect of a health-information literacy promotion program for individuals with Metabolic Syndrome (including its subtypes) based on the Health Empowerment Theory.
- Trial name
- NCT07051733
- Testing
- Health Information Literacy Enhancement
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meihua Ji
Obstructive Sleep Apnea, Insulin Resistance
Endothelial Damage and Atherosclerosis in Obstructive Sleep Apnea
The investigators hypothesize that obstructive sleep apnea (OSA) may lead to increased formation/accumulation of advanced glycation ends (AGEs), and that the increase in AGEs is contributed in part by increased insulin…
- Conditions
- Obstructive Sleep Apnea, Insulin Resistance, Endothelial Function, Oxidative Stress
- Trial name
- NCT00942643
- Testing
- CPAP machine
- Where
- Hong Kong
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Malaria
Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire
This study evaluates the benefit to use 1) insecticide residual sprayings, 2) larvicides, 3) Ivermectin for domestic animals and 4) behaviour change communication strategy to complement the universal coverage with LLINs through a…
- Trial name
- REACT (NCT03074435)
- Testing
- Indoor residual sprayings, Larvicide, BCC
- Where
- 2 sites in Burkina Faso, Côte d’Ivoire
- Volunteers
- 15,776 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement
Brain and Central Nervous System Tumors, Leukemia
Metabolic Syndrome in Childhood Cancer Survivors
RATIONALE: Gathering information about how often metabolic syndrome occurs in young survivors of childhood cancer may help doctors learn more about the disease.
- Conditions
- Brain and Central Nervous System Tumors, Leukemia, Lymphoma, Metabolic Syndrome
- Trial name
- NCT00920738
- Testing
- metabolic assessment, questionnaire administration
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Sarcopenia
High Intensity Resistance Training and Possible Sarcopenia
Studies conducted so far added the dietary supplements along with resistance training as an intervention, we could not determine whether the observed effects of the intervention were due to the training program and/or dietary…
- Trial name
- NCT05985616
- Testing
- High Intensity Resistance Training
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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