Clinical trials: Resuscitation
Cardiac Arrest With Successful Resuscitation
A Novel Patient Decision Aid for Surrogate Decision Makers of Comatose Survivors of Cardiac Arrest
This study will test the feasibility and acceptability of deploying a decision aid for surrogate decision makers of comatose survivors of cardiac arrest early during hospitalization.
- Trial name
- NCT03908346
- Testing
- Decision Aid for Surrogate Decision Makers of Comatose Survivors of Cardiac Arrest
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Colorado, Denver
Cardiopulmonary Resuscitation (CPR), Nursing Education Research
Virtual Reality Application in Basic Life Support Practices
Introduction: This study investigates the effect of virtual reality (VR)-based training methods on the acquisition of cardiopulmonary resuscitation (CPR) skills and user attitudes within the framework of Kolb's Experiential…
- Conditions
- Cardiopulmonary Resuscitation (CPR), Nursing Education Research, Virtual Reality, Randomized Controlled Trial
- Trial name
- NCT07167303
- Testing
- VR Training), Traditional Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Cardiopulmonary Arrest, Pediatric ALL
Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest
The International Liaison Committee on Resuscitation regularly publishes a Consensus on Science with Treatment Recommendations but guidelines can nevertheless differ when knowledge gaps persist.
- Conditions
- Cardiopulmonary Arrest, Pediatric ALL, Resuscitation
- Trial name
- NCT05474170
- Testing
- AHA resuscitation sequence, ERC resuscitation sequence
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Out of Hospital Cardiac Arrest, Cardiac Arrest (CA)
Predicting 28-Day Survival in OHCA Patients
This prospective study aimed to identify clinical and laboratory predictors of return of spontaneous circulation (ROSC), 28-day survival, and favorable neurological outcomes in adult patients experiencing out-of-hospital cardiac…
- Trial name
- OHCAstd (NCT07023159)
- Testing
- Demographics, Comorbidities, Prehospital Variables
- Where
- Turkey (Türkiye)
- Volunteers
- 327 people
- Sponsor
- Haseki Training and Research Hospital
Acute Pancreatitis (AP), Acute Pancreatic Fluid Collection
Dextran 40 Plus Ringer's Lactate Vs. Ringer's Lactate Alone for Fluid Resuscitation in Acute Pancreatitis
This clinical trial aims to learn if a combination of Dextran 40 and Ringer's lactate solution can improve fluid resuscitation in mild and moderate acute pancreatitis (AP) and prevent complications.
- Conditions
- Acute Pancreatitis (AP), Acute Pancreatic Fluid Collection, Fluid Resuscitation
- Trial name
- NCT06835023
- Testing
- Ringer lactate (RLS), Dextran+Ringer Lactat(D+RLS)
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Satu Mare County Emergency Hospital
Neonatal Resuscitation, Apnea Neonatal
Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates
Many extremely premature infants require immediate help with breathing after birth. Positive pressure ventilation (PPV) using a device called a T-piece resuscitator is a common method.
- Trial name
- MVP (NCT06849596)
- Testing
- Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR)
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 780 people
- Sponsor
- Michelle Baczynski
Ventilation Therapy; Complications, Technical Skills
Educational Strategies for Maintaining Technical Skills in Neonatal Resuscitation for the Nursing Team
Despite efforts for initial training in neonatal resuscitation, health professionals show a decline in post-training skills, requiring continuing training.
- Conditions
- Ventilation Therapy; Complications, Technical Skills, Nurse's Role
- Trial name
- Neo-VPP (NCT06882018)
- Testing
- Repeated practice guided by peers, Instructor-guided deliberate practice
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ahmed Moussa
Education, Medical
Study of Virtual Simulated Resuscitation in Junior Clinicians
The investigators seek to examine the impact of virtual patient simulation on junior clinicians' resuscitation skills in an academic emergency department.
- Trial name
- NCT05201950
- Testing
- Virtual simulation, Team based in situ simulation
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Opioid-Use Disorder (OUD)
SafetyNet Program for Opioid Use Disorder (OUD)
The principal aim of this study is to determine whether a novel biopsychosocial intervention following opioid overdose (OD) affects 1) the frequency of secondary opioid OD events and 2) the proportion of individuals who remain…
- Trial name
- NCT04253782
- Testing
- Team Intervention
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- Yale University
Cardiac Surgery
Double Blind Randomized Trial of Saline vs Pentaspan for Resuscitation After Cardiac Surgery
This is a randomized double blind trial of the use of the use of colloids vs crystalloid solutions for resuscitation of patients after cardiac surgery.
- Trial name
- NCT00337805
- Testing
- Pentaspan
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cardiac Arrest, Intubation, Endotracheal
Pediatric Endotracheal Intubation
We hypothesized that the McGrath MAC EMS is beneficial for intubation of pediatric manikins while performing CPR. In the current study, we compared effectiveness of the McGrath MAC EMS and MIL laryngoscopes in child resuscitation…
- Trial name
- EMS (NCT02291653)
- Testing
- McGrath, MIL
- Where
- Poland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Antioxidative Stress, End Stage Renal Disease on Dialysis
A Novel Role of Alpha Lipoic Acid in Comparison With Selenium in Mitochondrial Resuscitation and miRNA-126 Expression in Hemodialysis Patients
An Open labeled, Paralled, Randomized, Prospective, study was conducted on 60 patients who were randomized into 3 groups, 22, 20 and 18 patients in Control, Selenium and, Thiotacid groups respectively.
- Trial name
- NCT05266794
- Testing
- Alpha lipoic acid, Selenium
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Ain Shams University
Airway Aspiration, Cardiopulmonary Arrest
Benefit of the SALAD Technique on CPR Quality During Intubation in Contaminated Airway
Management of airways in contaminated environments can compromise the quality of cardiopulmonary resuscitation (CPR). This study examined the effectiveness of SALAD (Suction Assisted Laryngoscopy Airway Decontamination) compared…
- Trial name
- NCT06427655
- Testing
- SALAD intubation
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Shock
CRUISE System in Flight
This is a prospective, observational, blinded clinical study with the purpose of assessing the safety of a non-invasive decision support system for the identification and management of shock (the CRUISE system).
- Trial name
- CRUISE (NCT07637240)
- Testing
- Observation blinded group with the purpose of assessing the safety of a non-invasive decision support system for the identification and management of shock (the CRUISE system).
- Volunteers
- 60 people
- Sponsor
- Hernando Gomez
Sepsis, Severe Sepsis
Preemptive Resuscitation for Eradication of Septic Shock
The purpose of this study is to assess the ability of an empiric resuscitation strategy compared to standard care to decrease the incidence of organ failure in normotensive sepsis patients.
- Trial name
- NCT01449721
- Testing
- Intravenous fluid
- Where
- 5 sites in United States
- Volunteers
- 142 people
- Sponsor
- Christiana Care Health Services
Cardiac Arrest With Successful Resuscitation, Cardiac Arrest, Cause Unspecified
Optimization of Transport and Use of a Mobile ECMO Team in Patients With Sudden Cardiac Arrest in the Moravian-Silesian Region
This study evaluates the feasibility of implementing a mobile extracorporeal membrane oxygenation (ECMO) team and optimizing patient transport logistics.
- Trial name
- NCT07009652
- Testing
- Extracorporeal cardiopulmonary resuscitation (ECPR)
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Cardiac Arrest
Intraosseous Access During Pediatric Resuscitation
The purpose of this study was to compare the Jamshidi, the BIG, the Cook, the EZIO intraosseous devices to standard peripheral venous catheterization during pediatric resuscitation.
- Trial name
- IOCPR (NCT02305511)
- Testing
- Peripheral venous catheterization, Jamshidi, BIG
- Where
- Poland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Cardiac Arrest With Successful Resuscitation
Gasping Improves Long-term Survival After Out-of-hospital Cardiac Arrest
The aim of our retrospective clinical study was to examine the association between agonal breathing, return of spontaneous circulation (ROSC), and long-term survival.
- Trial name
- NCT02998749
- Volunteers
- 584 people
- Sponsor
- Charles University, Czech Republic
Fluid Resuscitation Monitoring Non-invasively
The Relation Between Common Carotid Artery Diameter and Central Venous Pressure for Assessment of Intravascular Fluid Status After Major Surgeries: An Observational Study
Recently, bedside ultrasound has become an important tool for the simple and non-invasive hemodynamic assessment of critically ill patients.
- Trial name
- NCT04018443
- Testing
- common carotid artery diameter measurement
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Traumatic Shock
AVERT Shock: Arginine Vasopressin During the Early Resuscitation of Traumatic Shock
Trauma patients, who are transfused with multiple blood products to treat shock due to blood loss, frequently develop inappropriately low vasopressin levels.
- Trial name
- AVERTShock (NCT01611935)
- Testing
- Vasopressin
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Pennsylvania