Clinical trials: Risk Behavior
Colorectal Cancer, Early Onset Colorectal Cancer
Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
An increase in early-onset colorectal cancers (eoCRC), defined as a CRC before 50 years, is confirmed globally. CRC pathogenesis has been associated with several risk factors (family history, germline pathogenic variants…
- Conditions
- Colorectal Cancer, Early Onset Colorectal Cancer, Diet Habit, Risk Reduction
- Trial name
- DEMETRA (NCT05732623)
- Testing
- Semi Quantitative Food Frequency Questionnaire (SQFFQ)
- Where
- 8 sites in United States, Finland and 4 more
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- San Raffaele University
COVID-19 Infection
Evaluation of an Interactive Risk Information Tool to Increase COVID-19 Vaccination Incidence in Vaccine-hesitant People
Coronavirus (COVID-19) vaccines have saved millions of lives since release and remain a key tool in the fight against the pandemic.
- Trial name
- iWILL (NCT05193903)
- Testing
- Simulation, Text
- Where
- Germany
- Volunteers
- 1,188 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Sexual Assault, Substance Use
Nexus of Risk: Sexual Assault, Alcohol Use, and Risky Sex Among College Women
Sexual assault on college campuses has reached epidemic proportions, yet the etiological variables responsible for violence against women in these contexts remain unclear.
- Conditions
- Sexual Assault, Substance Use, Risky Health Behavior, Ema
- Trial name
- NCT05892692
- Testing
- Ecological Momentary Intervention
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Colorectal Cancer
Colorectal Cancer Screening Based on Predicted Risk
The primary objective is to study the effect of communicating individual CRC risk score and screening recommendations on appropriate screening uptake at six months in individuals at low, moderate and high risk of developing CRC.
- Trial name
- PRESENT (NCT05357508)
- Testing
- Intervention brochure, Control brochure
- Where
- Switzerland
- Volunteers
- 515 people, healthy volunteers welcome
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Substance Use
Neurocognitive Predictors of Health Risk Behaviors
This study proposes to extend the ongoing longitudinal study of health risk behaviors and obtain new data from former adolescents (followed previously from ages 13-22; Times 1-8) now from ages 23 to 28 (Times 9-11).
- Trial name
- NCT06941181
- Testing
- neurocognitive tasks
- Where
- 2 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Smoking Cessation, Smoking, Cigarette
Pictorial Warning Labels and Memory for Relative and Absolute Cigarette Health-risk Information Over Time in Teens
Pictorial cigarette warning labels (PWLs) are thought to increase risk knowledge, but experimental research has not examined PWLs' longer term effects on memory for health risks.
- Trial name
- NCT03500965
- Testing
- text-only PWL, graphic PWL, absolute risk
- Volunteers
- 422 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Smoking, Tobacco Use
Linking Brain Network Dynamics to Imminent Smoking Lapse Risk and Behavior
Most attempts to quit smoking end in relapse, or a return to regular smoking. One of the biggest threats to cessation is a lapse (i.e., any cigarette use during a quit attempt).
- Trial name
- NCT05572671
- Testing
- Laboratory task modeling smoking lapse behavior
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Penn State University
Stimulant Abuse, Criminal Behavior
Neurocognitive Abnormalities in Stimulant Abuse Among High-Risk Women
Substance use disorders and psychopathy are serious and costly mental health issues. Psychopathy is known to be associated with aberrant moral decision making and there is considerable interest in determining whether substance…
- Trial name
- NCT05845333
- Testing
- Decision task
- Where
- United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Anxiety Disorders, Oral Disease
Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior
Trait anxiety is the tendency of an individual to perceive environmental stimuli such as different events and situations as threatening; it's stable and reflects how an individual generally feels.
- Conditions
- Anxiety Disorders, Oral Disease, Periodontal Diseases, Periodontal Attachment Loss
- Trial name
- NCT04274855
- Where
- Egypt
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obesity, Metabolic; Complications
Effect of Carbonated Soft Drinks on the Body Weight
Compared to solid foods, the nutritional energy of drinks may bypass the appetite regulation leading to obesity development. Although drinks sweetened with aspartame are available the anticipated positive effect of these drinks…
- Conditions
- Obesity, Metabolic; Complications, Dietary Habits
- Trial name
- NCT00777647
- Testing
- Sugar-sweetened soft drink, Aspartame-sweetened soft drink, Semi-skimmed milk
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Smoking, Body Weight
Treating Adults at Risk for Weight Gain With Interactive Technology
Obesity represents a chronic disease associated with significant cardiovascular disease (CVD) morbidity and mortality. Weight gain in young adults adversely impacts the development of CVD risk factors.
- Trial name
- TARGIT (NCT01199185)
- Testing
- Smoking Cessation, Smoking Cessation plus Weight Loss
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Human Immunodeficiency Virus, Sexually Transmitted Infections
Project PRIDE (Promoting Resilience In Discriminatory Environments)
The specific aims are to: 1. Pilot test a randomized controlled trial of Project PRIDE for feasibility for subsequent research projects.
- Conditions
- Human Immunodeficiency Virus, Sexually Transmitted Infections, Anxiety, Depression
- Trial name
- NCT03528135
- Testing
- Project PRIDE
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Houston
Suicide
Suicide Ideation Intervention in Nigeria
The research will use the Social Ecologic Model of behavior and WHO mhGAP framework to design a comprehensive intervention across three levels (individual, interpersonal, and social) of influence.
- Trial name
- NCT05103540
- Testing
- Comprehensive SEM-Based Program
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Babcock University
Cardiovascular Diseases, Cardiovascular Risk Factor
Using Big Data to Conduct Innovative Cardiovascular Clinical Trials
Traditional randomized clinical trials (RCTs) have provided extremely valuable information on medical therapies and procedures that have changed the way heart diseases are treated.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Dyslipidemias
- Trial name
- NCT04067297
- Testing
- Lipid management toolbox
- Where
- Canada
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical Evaluative Sciences
Metabolic Disorders, Physical Inactivity
Interactive Roles of Cardiorespiratory Fitness and Adiposity on Glucose and Vascular Control After Physical Inactivity
The far-reaching negative health effects of the reduced physical activity (RPA) epidemic are often overlooked by the general population and health professionals.
- Conditions
- Metabolic Disorders, Physical Inactivity, Vascular Disease Risk
- Trial name
- NCT06842225
- Testing
- reduced physical activity
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Miami University
Non-alcoholic Fatty Liver Disease, Obesity
Effect of Exercise on Hepatic Fat in Overweight Children
The objective of the present study is to evaluate the effect of 6 months exercise intervention program on hepatic fat fraction in overweight children.
- Conditions
- Non-alcoholic Fatty Liver Disease, Obesity, Metabolic Syndrome
- Trial name
- EFIGRO (NCT02258126)
- Testing
- Multidisciplinary intervention program
- Where
- Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Dementia
Mediterranean Diet, Exercise and Dementia Risk in UK Adults
In cohort studies, a Mediterranean Dietary Pattern (MDP) has been consistently associated with reduced dementia incidence. The efficacy of a MDP to prevent dementia has never been directly demonstrated by RCTs, with existing…
- Trial name
- MedEx-UK (NCT03673722)
- Testing
- Foods consistent with a MDP, Physical Activity, Control
- Where
- 3 sites in United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Tobacco Use Disorder
Tobacco Use Among Arab American Youth
Michigan has the 10th highest smoking rate in the nation. Smoking rates are also very high in the Middle East and in Arab American families.
- Trial name
- NCT00059514
- Testing
- Modified Project Toward No Tobacco Use
- Where
- United States
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Alcohol Risk Behaviors
Mitigating the Disinhibiting Effects of Alcohol With Transcranial Magnetic Stimulation
The goal of this clinical trial is to learn how a specific type of brain stimulation affects alcohol-related decision-making and self-control in adults who drink alcohol.
- Trial name
- NCT07188376
- Testing
- Intermittent Theta Burst Stimulation, Continuous Theta Burst Stimulation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Michael J. Wesley, PhD
Adolescent Sexual Risk Behaviors
Effects of a Worksite Parenting Program
Many adolescents in the U.S., even very young adolescents, are engaging in sexual risk behaviors that put them at risk for sexually transmitted diseases (STDs) and unintended pregnancy.
- Trial name
- NCT00465010
- Testing
- Talking Parents, Healthy Teens
- Where
- United States
- Volunteers
- 1,252 people, healthy volunteers welcome
- Sponsor
- RAND
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