Clinical trials: Sciatic Nerve Block
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery
One technique for the nerve block involves injecting the numbing medicine where the nerve is together (higher up in the back of the thigh).
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot
- Trial name
- NCT01550094
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Popliteal Sciatic Nerve Block
Comparing Classical Approach and Crosswise Approach to Popliteal Sciatic Nerve Block
Sensory and motor innervation below the knee is provided mainly by the popliteal-sciatic nerve except for a variable area of the medial leg supplied by the saphenous nerve.
- Trial name
- NCT07134608
- Testing
- Popliteal Plexus Block with 20 ml
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Adult, Regional Anesthesia Morbidity
How Do We Ultrasound-Guided Popliteal Approach Sciatic Nerve Block?
The aim of this prospective, randomized, observer-blind study to compare subparaneural approach injection with interneural approach injection in popliteal sciatic nerve blocks.
- Conditions
- Adult, Regional Anesthesia Morbidity, Anesthesia Injection Site
- Trial name
- NCT06372691
- Testing
- Subparaneural Injection (Grup S), Block, Interneural Injection (Grup I), Block
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Anesthesia
Application of Combined Lumbar Plexus and Sciatic Nerve Block
The research is to study the effectiveness and safety of combined lumbar plexus and sciatic nerve block by the guide of peripheral nerve stimulator (PNS) in unilateral knee replacement.There have be some papers which supported…
- Trial name
- NCT02084368
- Testing
- Nerve block, Combined spinal and epidural anesthesia, Ropivacaine
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Anesthesia Local
Comparison of Combined Sciatic(Winnie's) Femoral Nerve Block, and Subarachnoid Block Anesthesia for Lower Limb Surgery
60 ASA grades- I, II or III patients, undergoing lower limb surgeries, will be randomly allocated in 2 groups of 30 patients each.
- Trial name
- NCT02713685
- Testing
- Subarachnoid block, combined Femoral and Sciatic nerve block
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Diabetes Type 2
Evaluation of Block Duration in Type 2 Diabetes Patients
Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after…
- Trial name
- Diabeteblock (NCT01704612)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pierre and Marie Curie University
Lower Extremity Surgery
Postoperative Quality of Recovery After Combined Lumbar Plexus-Sciatic Nerve Block (LPB-SNB)
The goal of this clinical trial is to evaluate the efficacy of lumbar plexus-sciatic nerve block (LPB-SNB) by comparing the postoperative quality of recovery as assessed by the Quality of Recovery-40 (QoR-40) questionnaire, in…
- Trial name
- NCT06301503
- Testing
- USG Guided Combined LPB-SNB with Isobaric Bupivacaine, Control
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Udayana University
Knee Injuries
Femoral/Sciatic Block for Knee Surgery
Knee arthroplasty has a high potential for postoperative pain. This study compares analgesia and postoperative bleeding from intrathecal morphine with the continuous femoral and a single-shot sciatic nerve blockades.
- Trial name
- NCT02882152
- Testing
- femoral nerve blockade, morphine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Foot Surgery, Ankle Surgery
Pre-post Spinal Popliteal Block
This is a retrospective chart review to determine the non-inferiority of performing lower extremity peripheral nerve block placement under spinal anesthesia compared to its pre-spinal counterpart.
- Trial name
- NCT05354791
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Healthy, Nerve Block
Phase I Study of Ropivacaine, Clonidine, and Betamethasone Combination for Sciatic Nerve Block in the Popliteal Region
This is a national, single-center, dose-escalation Phase I study to investigate the safety, pharmacokinetics, and efficacy of a combination containing Ropivacaine, Clonidine, and Betamethasone (Ropiclobet) in healty volunteers.
- Trial name
- RopiCloBet (NCT06781632)
- Testing
- ropivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- PHARMAFINA
Total Knee Arthroplasty
Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)
The purpose of this study is to find a better way to make patients comfortable after their knee surgery. The investigators compared three ways of providing pain relief, either by use of a nerve block at the femoral and sciatic…
- Trial name
- NCT02223364
- Testing
- Peripheral nerve blocks with Bupivacaine, Intra articular injection with Ropivacaine, Intra articular injection with liposomal bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Adverse Effect, Feasibility Study
Feasibility and Safety of Sciatic Nerve Paraneural Sheath Block Using a Mid-Femoral Lateral Approach
This study is designed as a randomized controlled trial aiming to evaluate the feasibility and safety of ultrasound-guided mid-femoral lateral approach sciatic nerve paraneural sheath block, in order to provide a new sciatic…
- Conditions
- Adverse Effect, Feasibility Study, Safety and Effectiveness
- Trial name
- iSNB-LF (NCT07366853)
- Testing
- Ultrasound-guided lateral mid-femoral sciatic nerve block, Ultrasound-guided popliteal sciatic nerve block
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Anterior Cruciate Ligament (ACL) Tear
Sciatic Technique Comparison of Nerve Blockade for Pain Control Following Hamstring Autograft Harvest in Adolescents
The purpose of this research is to compare the effect of single-injection sciatic PNB to continuous sciatic PNB on 1) postoperative pain control as measured by self-reported pain scores, pain medication use, and unplanned…
- Trial name
- NCT02947633
- Testing
- Single-injection sciatic PNB, Continuous sciatic PNB
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Post Operative Pain
Ketamine and Dexmedetomidine Comparative Study
In this study, the investigators will compare the effect of adding ketamine and dexmedetomidine to bupivacaine in US-guided combined sciatic and femoral nerve blocks as regards the onset and duration of the block, postoperative…
- Trial name
- NCT06032624
- Testing
- combined ultra-sound guided femoral and sciatic nerve block.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery
The purpose of this study is to compare injecting local anesthetic (numbing medication) in different patterns around a major nerve in the leg.
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot
- Trial name
- NCT01542840
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Postoperative Pain
Effect of Posterior Femoral Cutaneous Nerve Block on Postoperative Posterior Lateral Knee Analgesia in Patients With TKA
The aim of this study was to observe the effects of posterior femoral cutaneous nerve block combined with sciatic and saphenous nerve block compared with sciatic and saphenous nerve block alone on postoperative posterior side of…
- Trial name
- NCT06522620
- Testing
- Posterior Femoral Cutaneous Nerve Combined With Proximal Sciatic and Saphenous Nerve Block, Simple Sciatic and Saphenous Nerve Blocks
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Regional Anesthesia, Sciatic Nerve Block
Comparing Through-the-Needle With Suture-Method Catheter Designs for Popliteal Nerve Blocks
Following painful surgical procedures, postoperative analgesia is often provided with a single-injection peripheral nerve block.
- Trial name
- NCT03442036
- Testing
- Suture-Method Technique, Through-the-Needle Technique
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hallux Valgus, Surgery
Continuous Versus Automated Bolus Infusion in Sciatic Nerve Catheters
This study is developed to determine if the local anaesthetic dose can be reduced by the use of intermittent bolus technique compared to continuous infusion when the nerve catheter is placed underneath the paraneurium by…
- Trial name
- NCT02293330
- Testing
- continuous infusion of levobupivacaine, Intermittent bolus infusion of levobupivacaine
- Where
- Belgium
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Analgesia in Total Knee Arthroplasty
Continuous Femoral and Tibial Nerve Blocks in TKA Patients
The purpose of this study is to evaluate whether a new regional anesthesia technique would provide better pain control, patient satisfaction, less narcotic use and no symptoms of foot drop after knee replacement surgery.
- Trial name
- NCT01680692
- Testing
- Ropivicaine, Continuous Femoral Nerve Catheter, Continuous Tibial Nerve Catheter
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Postoperative Pain Management, Postoperative Pain
Comparative Efficacy of Sciatic and Femoral Blocks in Ankle Surgery
Comparison of Anesthetic and Postoperative Analgesic Efficacy of Femoral and Popliteal Sciatic Block vs Femoral and Anterior Sciatic Block in Ankle Surgery
- Conditions
- Postoperative Pain Management, Postoperative Pain, Analgesia, Nerve Blocks
- Trial name
- NCT06758245
- Testing
- femoral and anterior sciatic nerve block, femoral and popliteal sciatic nerve block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital