Clinical trials: Sciatica Pain
Osteoarthritis, Pain Intensity Assessment
A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic Pain
The purpose of this study is to evaluate the safety of CG5503 base Immediate Release(IR) 50 mg or 100 mg taken every 4 to 6 hours as needed over the long-term exposure of 90 days in patients who have chronic pain.
- Conditions
- Osteoarthritis, Pain Intensity Assessment, Arthralgia, Sciatica
- Trial name
- NCT00364546
- Testing
- CG 5503;tapentadol
- Volunteers
- 877 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Venous Thromboembolism
Dalteparin vs Unfractionated Heparin For The Prevention Of Venous Thromboembolism (VTE) In Hospitalized Acutely Ill Medical Patients
The purpose of this study is to compare the efficacy and safety of dalteparin vs unfractionated heparin for the prevention of VTE (Venous Thromboembolism) in hospitalized acutely ill medical patients.
- Trial name
- NCT00445328
- Testing
- Dalteparin (Fragmin), Unfractionated heparin
- Where
- 7 sites in India
- Volunteers
- 84 people
- Sponsor
- Pfizer
Disc Herniation With Radiculopathy
A Randomized Trial Comparing SpineJet® Hydrodiscectomy to Open Lumbar Microdiscectomy for Treatment of Lumbar Radiculopathy Due to Disc Herniation
The purpose of this study is to compare a standard surgical procedure, open surgical microdiscectomy, used primarily to relieve leg pain and repair disc herniation to a newer surgical procedure, hydrodiscectomy with Spinejet®.
- Trial name
- NCT00384007
- Testing
- Hydrodiscectomy with Spinejet
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Pinnacle Pain Medicine
Sciatica, Low Back Pain
Artificial Intelligence (AI)-Based Prediction of Treatment Response in Sciatica Patients Receiving Transforaminal Epidural Steroid Injection
This prospective observational study aims to develop artificial intelligence (AI)-based predictive models to estimate treatment response in patients with sciatica undergoing transforaminal epidural steroid injection (TFESI).
- Conditions
- Sciatica, Low Back Pain, Lumbar Spinal Stenosis, Radiculopathy
- Trial name
- NCT07080307
- Where
- Turkey (Türkiye)
- Volunteers
- 1,500 people
- Sponsor
- Marmara University
Chronic Sciatica
Efficacy and Mechanism of Acupuncture for Chronic Sciatica Using fMRI
This research is planned to build a basis about the efficacy and mechanism of acupuncture on pain and emotional disorder in patients with chronic sciatica using fMRI.
- Trial name
- NCT03350789
- Testing
- Real acupuncture
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Kyung Hee University Hospital at Gangdong
Sciatica, Low Back Pain
Effect of Muscle Energy Techniques on Functional Abilities in Patients With Discogenic Unilateral Sciatica
The purpose of the study to investigate the effect of muscle energy techniques on functional abilities of patients with chronic discogenic unilateral sciatica and to explain it from a physiological and functional point of view
- Trial name
- NCT04918238
- Testing
- Conventional program, Muscle energy technique
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Horus University
Sciatica
A Study to Evaluate the Safety and Efficacy of Subcutaneously Administered REGN475(SAR164877) in Patients With Sciatic Pain
This is a phase 2, randomized, double-blind, parallel-group, single dose study to evaluate the safety and efficacy of 2 dose levels of REGN475 compared with placebo in patients with sciatic pain.
- Trial name
- NCT00991172
- Testing
- REGN475
- Where
- 30 sites in United States
- Volunteers
- 159 people
- Sponsor
- Regeneron Pharmaceuticals
Sciatica
Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Sciatica
The purpose of this study is to determine whether anti-inflammatory drugs or glucocorticoids are effective in the treatment of acute sciatica
- Trial name
- TéAGS (NCT01816334)
- Testing
- methylprednisolone, Ketoprofen, Sodium Chloride
- Where
- 2 sites in France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Sciatica
Ultrasound-guided Caudal or Interlaminar Corticosteroid Epidural Injection for Sciatica
An open-label randomized trial to compare the efficacy of ultrasound-guided caudal and interlaminar corticosteroid injections for the treatment of lumbar disk herniation-related sciatica.
- Trial name
- HiatUS (NCT02897336)
- Testing
- ultrasound-guided, interlaminar
- Where
- France
- Sponsor
- University Hospital, Caen
Therapy, Acupuncture, MRI, Functional
Acupuncture Treatment for Chronic Sciatica: the Neuroimaging Pain-network Study
Sciatica is a common pain disorder in the neurological clinic that typically present as low back or gluteal pain and may radiate to one leg with motor or sensory complaint.
- Trial name
- NCT03489681
- Testing
- acupuncture
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Sciatica, Intervertebral Disc Disorder
Alternative and Integrative Therapy for Lumbar Disk Herniation
The investigators report management of lumbar disc herniation with severe sciatic pain using an integrative complementary and alternative medicine approach with a 5 year follow-up.
- Trial name
- NCT01989403
- Testing
- herbal medicine, acupuncture, bee-venom acupuncture, and Chuna manipulation
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Sciatica
Effectiveness of Combined Neural Mobilization With Manual Myofascial Release for Sciatic Pain Relief
This study will address to evaluate and compare both Neural mobilization and Manual Myofascial Release of piriformis and Lumbar muscles in sciatic pain with the aim of evaluating and identifying the most effective intervention…
- Trial name
- NCT06947785
- Testing
- Combined Neural Mobilization with Manual myofascial Release, Neural Mobilization, Manual Myofascial Release
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Low Back Pain, Sciatica
Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain
The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to…
- Conditions
- Low Back Pain, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06275750
- Testing
- Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.)
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital Civil de Guadalajara
Herniated Disc, Lower Back Pain
Chiropractic Prone Distraction for Lower Back Pain
Back pain is a major cause of disability in the United States. The lifetime prevalence of low back pain is estimated at 60-90%. Back pain has conservatively been estimated to involve total direct and indirect costs of over $25…
- Conditions
- Herniated Disc, Lower Back Pain, Sciatica
- Trial name
- NCT00269503
- Testing
- Prone Distraction, Side-Posture Manipulation, Side-Posture Manipulation & Prone Distraction
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Samueli Institute for Information Biology
Intervertebral Disc Displacement, Sciatica
The Effectiveness of Doin (Conduction Exercise) of the Pelvic Joint for HLD With Radiating Leg Pain
A prospective pilot study will be conducted to investigate the effectiveness and safety in herniated lumbar disc (HLD) patients receiving integrative Korean medicine treatment including Doin (conduction exercise) at a Korean…
- Conditions
- Intervertebral Disc Displacement, Sciatica, Sciatic Radiculopathy
- Trial name
- NCT03571503
- Testing
- Doin (conduction exercise), Herbal medicine, Chuna manual therapy
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jaseng Medical Foundation
Lumbar Radiculopathy
Comparative Effects of Dynamic Stretching Versus Slider Neurodynamic Technique In Patients With Lumbar Radiculopathy
This study will be a randomised clinical trial conducted at the University of Lahore Teaching Hospital, Lahore, Pakistan. A total of 72 participants will be selected and randomly allocated into two treatment groups (36…
- Trial name
- NCT07384832
- Testing
- Dynamic stretching, slider neurodynamic mobilization, Routine physiotherapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Low Back Pain, Radiculopathy Lumbar
The Effect of Accelerometer Guided App Feedback on Change in Activity in Patients With Low Back
In a cross-over, open-label, randomized, controlled trial, the investigators aim to determine if the daily activity level in patients with LBP can be increased via feedback from an app, connected to a wearable sensor of physical…
- Conditions
- Low Back Pain, Radiculopathy Lumbar, Sciatica
- Trial name
- NCT04695912
- Testing
- The SENS motion® sensor
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Spinal Deformity
Sagittal Balance Through Ages
The parameters of the sagittal balance of the cervical, thoracic and lumbar spine vary according to the types of spino-pelvic organization (types 1-4 according to Roussouly).
- Trial name
- ESTA (NCT04467775)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Strasbourg, France
Sciatica, Electroacupuncture
Effectiveness of Electro-acupuncture and Manual Therapy on Pain and Fucntion in Patients With Sciatica
The aims of the study are: To study the pain efficacy of an electroacupuncture and manual therapy protocol versus the use of manual therapy in patients with sciatica.
- Conditions
- Sciatica, Electroacupuncture, Manual Therapy
- Trial name
- NCT04764890
- Testing
- Electroacupuncture, Manual therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- CEU San Pablo University
Herniated Disc, Sciatica
Intradiscal Discogel® in Resistant Sciatica
Sciatica due to herniated disc is a major cause of disability in young adults. Surgery is the gold-standard and the only controlled treatment in case of failure of conservative treatment.
- Conditions
- Herniated Disc, Sciatica, Persistent Pain, Leg
- Trial name
- EDIS (NCT02313350)
- Testing
- Chemonucleolysis with Discogel, open discectomy
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris